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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

TG4010 immunotherapy and first-line chemotherapy for advanced non-small-cell lung cancer (TIME): results from the phase 2b part of a randomised, double-blind, placebo-controlled, phase 2b/3 trial.

PMID: 26727163
Journal: LANCET ONCOLOGY
Year: 2016
Reference: Lancet Oncol. 2016 Feb;17(2):212-223. doi: 10.1016/S1470-2045(15)00483-0. Epub 2015 Dec 23.
Impact factor: 26.509
Publication type: Paper in international publication
Authors: Palanche, Tania, Quoix, Elisabeth, Lena, Herve, Losonczy, Gyorgy, Forget, Frederic, Chouaid, Christos, Papai, Zsolt, Gervais, Radj, Ottensmeier, Christian, Szczesna, Aleksandra et al.
DOI: 10.1016/S1470-2045(15)00483-0

The 11-year long-term follow-up study from the randomized BENEFIT CIS trial.

PMID: 27511182
Journal: NEUROLOGY
Year: 2016
Reference: Neurology. 2016 Sep 6;87(10):978-87. doi: 10.1212/WNL.0000000000003078. Epub 2016 Aug 10.
Impact factor: 8.166
Publication type: Paper in international publication
Authors: Rice, G, Montalban, Xavier, Hartung, Hans-Peter, Hemmer, Bernhard, Fox, Edward J, Barkhof, Frederik, Schippling, Sven, Schulze, Andrea, Pleimes, Dirk, Pohl, Christoph et al.
DOI: 10.1212/WNL.0000000000003078

The 2015 International Society for Heart and Lung Transplantation Guidelines for the management of fungal infections in mechanical circulatory support and cardiothoracic organ transplant recipients: Executive summary.

PMID: 26970469
Journal: JOURNAL OF HEART AND LUNG TRANSPLANTATION
Year: 2016
Reference: J Heart Lung Transplant. 2016 Mar;35(3):261-82. doi: 10.1016/j.healun.2016.01.007. Epub 2016 Jan 19.
Impact factor: 7.509
Publication type: Editorail in international publication
Authors: Husain, Shahid, Sole, Amparo, Alexander, Barbara D, Aslam, Saima, Morrissey, Orla, Avery, Robin, Benden, Christian, Billaud, Eliane M, Chambers, Daniel, Danziger-Isakov, Lara et al.
DOI: 10.1016/j.healun.2016.01.007

The addition of ofatumumab to the conditioning regimen does not improve the outcome of patients with high-risk CLL undergoing reduced intensity allogeneic haematopoietic cell transplantation: a pilot trial from the GETH and GELLC (CLL4 trial).

PMID: 27214073
Journal: BONE MARROW TRANSPLANTATION
Year: 2016
Reference: Bone Marrow Transplant. 2016 Oct;51(10):1404-1407. doi: 10.1038/bmt.2016.145. Epub 2016 May 23.
Impact factor: 3.636
Publication type: Paper in international publication
Authors: Montesinos, P, Cabrero, M, Valcarcel, D, Rovira, M, Garcia-Marco, J A, Loscertales, J, Moreno, C, Duarte, R, Terol, M J, Villamor, N et al.
DOI: 10.1038/bmt.2016.145

The cancer stem-cell signaling network and resistance to therapy.

PMID: 27434881
Journal: CANCER TREATMENT REVIEWS
Year: 2016
Reference: Cancer Treat Rev. 2016 Sep;49:25-36. doi: 10.1016/j.ctrv.2016.07.001. Epub 2016 Jul 9.
Impact factor: 7.983
Publication type: Review in international publication
Authors: Carnero, A, Garcia-Mayea, Y, Mir, C, Lorente, J, Rubio, I T, LLeonart, M E et al.
DOI: 10.1016/j.ctrv.2016.07.001

The challenge of diagnosing a mixed asthma-COPD phenotype (ACOS) in clinical practice.

PMID: 26968234
Journal: Therapeutic Advances in Respiratory Disease
Year: 2016
Reference: Ther Adv Respir Dis. 2016 Apr;10(2):175-8. doi: 10.1177/1753465816630209.
Impact factor: 2.286
Publication type: Paper in international publication
Authors: Garcia-Garcia, Maria Del Carmen, Hernandez-Borge, Jacinto, Barrecheguren, Miriam, Miravitlles, Marc et al.
DOI: 10.1177/1753465816630209

The changing landscape in drug resistant-tuberculosis: an analysis of recent advances.

PMID: 26954921
Journal: Expert Review of Respiratory Medicine
Year: 2016
Reference: Expert Rev Respir Med. 2016 Jun;10(6):603-6. doi: 10.1586/17476348.2016.1164042. Epub 2016 Mar 28.
Impact factor: 2.176
Publication type: Editorail in international publication
Authors: Sanchez-Montalva, Adrian, Bhavaraju, Rajita, Monedero, Ignacio, Caminero, Jose A et al.
DOI: 10.1586/17476348.2016.1164042

The clinical perspective: How to personalise treatment in MS and how may biomarkers including imaging contribute to this?

PMID: 27465613
Journal: Multiple Sclerosis Journal
Year: 2016
Reference: Mult Scler. 2016 Aug;22(2 Suppl):18-33. doi: 10.1177/1352458516650739.
Impact factor: 4.671
Publication type: Paper in international publication
Authors: Trojano, Maria, Palace, Jacqueline, Comabella, Manuel, Vermersch, Patrick, Berger, Thomas, Gold, Ralf, Lukas, Carsten, Rovira, Alex, Meesen, Bianca, Chard, Declan et al.
DOI: 10.1177/1352458516650739

The Complementarity Between Protein-Specific and General Pathogenicity Predictors for Amino Acid Substitutions.

PMID: 27397615
Journal: HUMAN MUTATION
Year: 2016
Reference: Hum Mutat. 2016 Oct;37(10):1013-24. doi: 10.1002/humu.23048. Epub 2016 Aug 8.
Impact factor: 5.089
Publication type: Paper in international publication
Authors: Riera, Casandra, Padilla, Natalia, de la Cruz, Xavier et al.
DOI: 10.1002/humu.23048

The Core Outcome Measures Index (COMI) is a responsive instrument for assessing the outcome of treatment for adult spinal deformity.

PMID: 26519374
Journal: EUROPEAN SPINE JOURNAL
Year: 2016
Reference: Eur Spine J. 2016 Aug;25(8):2638-48. doi: 10.1007/s00586-015-4292-4. Epub 2015 Oct 30.
Impact factor: 2.066
Publication type: Paper in international publication
Authors: Mannion, A F, Vila-Casademunt, A, Domingo-Sabat, M, Wunderlin, S, Pellise, F, Bago, J, Acaroglu, E, Perez-Grueso, F S, Obeid, I, Kleinstuck, F S et al.
DOI: 10.1007/s00586-015-4292-4

The DESCARTES-Nantes survey of kidney transplant recipients displaying clinical operational tolerance identifies 35 new tolerant patients and 34 almost tolerant patients.

PMID: 26763669
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2016
Reference: Nephrol Dial Transplant. 2016 Jun;31(6):1002-13. doi: 10.1093/ndt/gfv437. Epub 2016 Jan 12.
Impact factor: 4.085
Publication type: Paper in international publication
Authors: Sever, Mehmet Sukru, Massart, Annick, Pallier, Annaick, Pascual, Julio, Viklicky, Ondrej, Budde, Klemens, Spasovski, Goce, Klinger, Marian, Colak, Hulya, Courtney, Aisling et al.
DOI: 10.1093/ndt/gfv437

The effect of individual isometric muscle loading on the alignment of the base of the thumb metacarpal: a cadaveric study.

PMID: 26253421
Journal: Journal of Hand Surgery-European Volume
Year: 2016
Reference: J Hand Surg Eur Vol. 2016 May;41(4):374-9. doi: 10.1177/1753193415597114. Epub 2015 Aug 6.
Impact factor: 1.868
Publication type: Paper in international publication
Authors: Hagert, E, Megerle, K, Mobargha, N, Esplugas, M, Garcia-Elias, M, Lluch, A et al.
DOI: 10.1177/1753193415597114

The Effect of Supplemental Oxygen in Obesity Hypoventilation Syndrome.

PMID: 27568890
Journal: Journal of Clinical Sleep Medicine
Year: 2016
Reference: J Clin Sleep Med. 2016 Oct 15;12(10):1379-1388.
Impact factor: 2.71
Publication type: Paper in international publication
Authors: Masa, Juan F, Corral, Jaime, Romero, Auxiliadora, Caballero, Candela, Teran-Santos, Joaquin, Alonso-Alvarez, Maria L, Gomez-Garcia, Teresa, Gonzalez, Monica, Lopez-Martinez, Soledad, De Lucas, Pilar et al.
DOI: 10.5664/jcsm.6194

The effectiveness of electrocautery ablation for the treatment of high-grade anal intraepithelial neoplasia in HIV-infected men who have sex with men.

PMID: 26688291
Journal: HIV MEDICINE
Year: 2016
Reference: HIV Med. 2016 Aug;17(7):524-31. doi: 10.1111/hiv.12352. Epub 2015 Dec 21.
Impact factor: 3.988
Publication type: Paper in international publication
Authors: Tallada, N, Guelar, A, Crespo, M, Ocana, I, Ribera, E, Falco, V, Navarro, J, Landolfi, S, Burgos, J, Curran, A et al.
DOI: 10.1111/hiv.12352

The efficacy of aclidinium/formoterol on lung function and symptoms in patients with COPD categorized by symptom status: a pooled analysis.

PMID: 27621610
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2016
Reference: Int J Chron Obstruct Pulmon Dis. 2016 Aug 29;11:2041-53. doi: 10.2147/COPD.S114566. eCollection 2016.
Impact factor: 3.046
Publication type: Paper in international publication
Authors: Miravitlles, Marc, Chapman, Kenneth R, Chuecos, Ferran, Ribera, Anna, Gil, Esther Garcia et al.
DOI: 10.2147/COPD.S114566

The ERS-endorsed official ATS/CDC/IDSA clinical practice guidelines on treatment of drug-susceptible tuberculosis.

PMID: 27587550
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2016
Reference: Eur Respir J. 2016 Oct;48(4):963-971. doi: 10.1183/13993003.01356-2016. Epub 2016 Sep 1.
Impact factor: 8.332
Publication type: Clinical guide
Authors: Sotgiu, Giovanni, Nahid, Payam, Loddenkemper, Robert, Abubakar, Ibrahim, Miravitlles, Marc, Migliori, Giovanni Battista et al.
DOI: 10.1183/13993003.01356-2016

The European Cancer Patient's Bill of Rights, update and implementation 2016.

PMID: 28848664
Journal: ESMO open
Year: 2016
Reference: ESMO Open. 2017 Jan 6;1(6):e000127. doi: 10.1136/esmoopen-2016-000127. eCollection 2016.
Impact factor: 0
Publication type: Editorail in international publication
Authors: Hojgaard, Liselotte, Lowenberg, Bob, Selby, Peter, Lawler, Mark, Banks, Ian, Law, Kate, Albreht, Tit, Armand, Jean-Pierre, Barbacid, Mariano, Barzach, Michele et al.
DOI: 10.1136/esmoopen-2016-000127

The ever-expanding ERS fellowship programmes: achievements over the past 3 years.

PMID: 27581399
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2016
Reference: Eur Respir J. 2016 Sep;48(3):595-9. doi: 10.1183/13993003.01146-2016.
Impact factor: 8.332
Publication type: Editorail in international publication
Authors: Holgate, Stephen T, Brusselle, Guy G, Pannetier, Carine, Tonia, Thomy, Belvisi, Maria G, Morty, Rory E, Rohde, Gernot, Miravitlles, Marc, Forrest, Kathryn A, Genton, Celine et al.
DOI: 10.1183/13993003.01146-2016

The Evolving Role of Nivolumab in Non-Small-Cell Lung Cancer for Second-Line Treatment: A New Cornerstone for Our Treatment Algorithms. Results From an International Experts Panel Meeting of the Italian Association of Thoracic Oncology.

PMID: 26908078
Journal: Clinical Lung Cancer
Year: 2016
Reference: Clin Lung Cancer. 2016 May;17(3):161-8. doi: 10.1016/j.cllc.2016.01.004. Epub 2016 Jan 28.
Impact factor: 3.03
Publication type: Review in international publication
Authors: Gridelli, Cesare, Besse, Benjamin, Brahmer, Julie Renee, Crino, Lucio, Felip, Enriqueta, de Marinis, Filippo et al.
DOI: 10.1016/j.cllc.2016.01.004

The Fenix II study: A longitudinal study of psychopathology among burn patients.

PMID: 27233675
Journal: BURNS
Year: 2016
Reference: Burns. 2016 Sep;42(6):1201-11. doi: 10.1016/j.burns.2016.01.026. Epub 2016 May 24.
Impact factor: 1.904
Publication type: Paper in international publication
Authors: Arguello, Jose Maria, Casas, Miguel, Tasque-Cebrian, Ruth, Giannoni-Pastor, Anna, Fidel-Kinori, Sara Guila, Eiroa-Orosa, Francisco Jose et al.
DOI: 10.1016/j.burns.2016.01.026

The first volume of MSJ-ETC.

PMID: 28607713
Journal: Multiple sclerosis journal - experimental, transla
Year: 2016
Reference: Mult Scler J Exp Transl Clin. 2016 Jan 22;2:2055217315626042. doi: 10.1177/2055217315626042. eCollection 2016 Jan-Dec.
Impact factor: 0
Publication type: Editorail in international publication
Authors: Cohen, Jeffrey A, Kim, Ho Jin, Tintore, Mar et al.
DOI: 10.1177/2055217315626042

The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells.

PMID: 27541004
Journal: PLoS Pathogens
Year: 2016
Reference: PLoS Pathog. 2016 Aug 19;12(8):e1005829. doi: 10.1371/journal.ppat.1005829. eCollection 2016 Aug.
Impact factor: 7.003
Publication type: Paper in international publication
Authors: Torres-Torronteras, Javier, Marti, Ramon, Clotet, Bonaventura, Ampudia, Rosa M, Vives-Pi, Marta, Este, Jose A, Ballana, Ester, Puig, Teresa, Riveira-Munoz, Eva, Badia, Roger et al.
DOI: 10.1371/journal.ppat.1005829

The hypoxic microenvironment: A determinant of cancer stem cell evolution.

PMID: 27417124
Journal: BIOESSAYS
Year: 2016
Reference: Bioessays. 2016 Jul;38 Suppl 1:S65-74. doi: 10.1002/bies.201670911.
Impact factor: 4.725
Publication type: Review in national publication
Authors: Carnero, Amancio, Lleonart, Matilde et al.
DOI: 10.1002/bies.201670911

The IASLC Mesothelioma Staging Project: Proposals for Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Pleural Mesothelioma.

PMID: 27687963
Journal: Journal of Thoracic Oncology
Year: 2016
Reference: J Thorac Oncol. 2016 Dec;11(12):2089-2099. doi: 10.1016/j.jtho.2016.08.147. Epub 2016 Sep 26.
Impact factor: 5.04
Publication type: Paper in international publication
Authors: Friedberg, Joseph, Nowak, Anna K, Chansky, Kari, Rice, David C, Pass, Harvey I, Kindler, Hedy L, Shemanski, Lynn, Bille, Andrea, Rintoul, Robert C, Batirel, Hasan F et al.
DOI: 10.1016/j.jtho.2016.08.147