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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Additional mechanisms conferring genetic susceptibility to Alzheimer's disease.

PMID: 25914626
Journal: Frontiers in Cellular Neuroscience
Year: 2015
Reference: Front Cell Neurosci. 2015 Apr 9;9:138. doi: 10.3389/fncel.2015.00138. eCollection 2015.
Impact factor: 4.609
Publication type: Review in national publication
Authors: Calero, Miguel, Gomez-Ramos, Alberto, Calero, Olga, Soriano, Eduardo, Avila, Jesus, Medina, Miguel et al.
DOI: 10.3389/fncel.2015.00138

Adherence to prophylaxis and quality of life in children and adolescents with severe haemophilia A.

PMID: 25649244
Journal: HAEMOPHILIA
Year: 2015
Reference: Haemophilia. 2015 Jul;21(4):458-64. doi: 10.1111/hae.12618. Epub 2015 Feb 4.
Impact factor: 2.603
Publication type: Paper in international publication
Authors: Garcia-Dasi, M, Aznar, J A, Jimenez-Yuste, V, Altisent, C, Bonanad, S, Mingot, E, Lucia, F, Gimenez, F, Lopez, M Fernanda, Marco, P et al.
DOI: 10.1111/hae.12618

Adjuvant Fluorouracil, Leucovorin, and Oxaliplatin in Stage II to III Colon Cancer: Updated 10-Year Survival and Outcomes According to BRAF Mutation and Mismatch Repair Status of the MOSAIC Study.

PMID: 26527776
Journal: JOURNAL OF CLINICAL ONCOLOGY
Year: 2015
Reference: J Clin Oncol. 2015 Dec 10;33(35):4176-87. doi: 10.1200/JCO.2015.63.4238. Epub 2015 Nov 2.
Impact factor: 18.428
Publication type: Paper in international publication
Authors: Duval, Alex, de Gramont, Armand, Vernerey, Dewi, Chibaudel, Benoist, Bonnetain, Franck, Tijeras-Raballand, Annemilai, Scriva, Aurelie, Hickish, Tamas, Tabernero, Josep, Van Laethem, Jean Luc et al.
DOI: 10.1200/JCO.2015.63.4238

Adjuvant Ovarian Suppression in Premenopausal Breast Cancer.

PMID: 25495490
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2015
Reference: N Engl J Med. 2015 Jan 29;372(5):436-46. doi: 10.1056/NEJMoa1412379. Epub 2014 Dec 11.
Impact factor: 55.873
Publication type: Paper in international publication
Authors: Price, Karen N, Colleoni, Marco, Viale, Giuseppe, Coates, Alan S, Goldhirsch, Aron, Gelber, Richard D, Giobbie-Hurder, Anita, Ruepp, Barbara, Rabaglio-Poretti, Manuela, Francis, Prudence A et al.
DOI: 10.1056/NEJMoa1412379

Adult ADHD Screening in Alcohol-Dependent Patients Using the Wender-Utah Rating Scale and the Adult ADHD Self-Report Scale.

PMID: 24743975
Journal: Journal of Attention Disorders
Year: 2015
Reference: J Atten Disord. 2015 Apr;19(4):328-34. doi: 10.1177/1087054714529819. Epub 2014 Apr 17.
Impact factor: 3.779
Publication type: Paper in international publication
Authors: Roncero, Carlos, Rodriguez-Cintas, Laia, Ortega, Lluisa, Lligona, Anna, Fuentes, Sonia, Perez-Pazos, Jesus, Martinez-Luna, Nieves, Casas, Miguel, Daigre, Constanza et al.
DOI: 10.1177/1087054714529819

Advanced neuroprotection for brain ischemia: an alternative approach to minimize stroke damage.

PMID: 26138255
Journal: EXPERT OPINION ON INVESTIGATIONAL DRUGS
Year: 2015
Reference: Expert Opin Investig Drugs. 2015 Sep;24(9):1137-42. doi: 10.1517/13543784.2015.1065040. Epub 2015 Jul 3.
Impact factor: 5.528
Publication type: Paper in international publication
Authors: Ayuso, Maria Irene, Montaner, Joan et al.
DOI: 10.1517/13543784.2015.1065040

Advances in the management of multiple sclerosis symptoms: pathophysiology and assessment of spasticity in multiple sclerosis.

PMID: 26611266
Journal: Neurodegenerative disease management
Year: 2015
Reference: Neurodegener Dis Manag. 2015;5(6 Suppl):15-7. doi: 10.2217/nmt.15.56.
Impact factor: 0
Publication type: Paper in international publication
Authors: Tintore, Mar et al.
DOI: 10.2217/nmt.15.56

Afatinib versus erlotinib as second-line treatment of patients with advanced squamous cell carcinoma of the lung (LUX-Lung 8): an open-label randomised controlled phase 3 trial.

PMID: 26156651
Journal: LANCET ONCOLOGY
Year: 2015
Reference: Lancet Oncol. 2015 Aug;16(8):897-907. doi: 10.1016/S1470-2045(15)00006-6. Epub 2015 Jul 5.
Impact factor: 24.69
Publication type: Paper in international publication
Authors: Syrigos, Konstantinos, Soria, Jean-Charles, Felip, Enriqueta, Cobo, Manuel, Lu, Shun, Georgoulias, Vassilis, Li, Wei, Isla, Dolores, Guclu, Salih Z, Morabito, Alessandro et al.
DOI: 10.1016/S1470-2045(15)00006-6

Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trial.

PMID: 25892145
Journal: LANCET ONCOLOGY
Year: 2015
Reference: Lancet Oncol. 2015 May;16(5):583-94. doi: 10.1016/S1470-2045(15)70124-5. Epub 2015 Apr 16.
Impact factor: 24.69
Publication type: Paper in international publication
Authors: Rottey, Sylvie, Caponigro, Francesco, Castro, Gilberto Jr, Clement, Paul, del Campo, Joseph M, Cupissol, Didier, Degardin, Marian, Dietz, Andreas, Dreosti, Lydia Mary, Even, Caroline et al.
DOI: 10.1016/S1470-2045(15)70124-5

Aggressive Angiomyxoma: Imaging Findings in 3 Cases With Clinicopathological Correlation and Review of the Literature.

PMID: 26529675
Journal: JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY
Year: 2015
Reference: J Comput Assist Tomogr. 2015 Nov-Dec;39(6):914-21. doi: 10.1097/RCT.0000000000000305.
Impact factor: 1.411
Publication type: Review in international publication
Authors: Miguez Gonzalez, Javier, Dominguez Oronoz, Rosa, Lozano Arranz, Pilar, Calaf Forn, Francesc, Barrios Sanchez, Pedro, Garcia Jimenez, Angel et al.
DOI: 10.1097/RCT.0000000000000305

Alirocumab as Add-On to Atorvastatin Versus Other Lipid Treatment Strategies: ODYSSEY OPTIONS I Randomized Trial.

PMID: 26030325
Journal: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Year: 2015
Reference: J Clin Endocrinol Metab. 2015 Aug;100(8):3140-8. doi: 10.1210/jc.2015-1520. Epub 2015 Jun 1.
Impact factor: 6.209
Publication type: Paper in international publication
Authors: Bays, Harold, Gaudet, Daniel, Weiss, Robert, Ruiz, Juan Lima, Watts, Gerald F, Gouni-Berthold, Ioanna, Robinson, Jennifer, Zhao, Jian, Hanotin, Corinne, Donahue, Stephen et al.
DOI: 10.1210/jc.2015-1520

Alisporivir with peginterferon/ribavirin in patients with chronic hepatitis C genotype 1 infection who failed to respond to or relapsed after prior interferon-based therapy: FUNDAMENTAL, a Phase II trial.

PMID: 25412795
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2015
Reference: J Viral Hepat. 2015 Jul;22(7):596-606. doi: 10.1111/jvh.12360. Epub 2014 Nov 21.
Impact factor: 3.307
Publication type: Paper in international publication
Authors: Mazzella, G, Pol, S, Orsenigo, R, Brass, C, Alberti, A, Davis, G L, Rasenack, J, Buti, M, Flisiak, R, Kao, J-H et al.
DOI: 10.1111/jvh.12360

[Allergic asthma.]

PMID: 25433783
Journal: MEDICINA CLINICA
Year: 2015
Reference: Med Clin (Barc). 2015 Mar 9;144(5):216-22. doi: 10.1016/j.medcli.2014.08.009. Epub 2014 Nov 26.
Impact factor: 1.417
Publication type: Paper in national publication
Authors: Cardona, Victoria, Garriga, Teresa et al.
DOI: 10.1016/j.medcli.2014.08.009

Allogeneic haematopoietic stem cell transplantation for mitochondrial neurogastrointestinal encephalomyopathy.

PMID: 26264513
Journal: BRAIN
Year: 2015
Reference: Brain. 2015 Oct;138(Pt 10):2847-58. doi: 10.1093/brain/awv226. Epub 2015 Aug 10.
Impact factor: 9.196
Publication type: Paper in international publication
Authors: Accarino, Anna, Ferra, Christelle, Illa, Isabel, Beguin, Yves, Bakker, Jaap A, Boelens, Jaap J, de Coo, Irenaeus F M, Fay, Keith, Sue, Carolyn M, Nachbaur, David et al.
DOI: 10.1093/brain/awv226

Alpha1-antitrypsin deficiency: the contribution of national registries to the understanding of the disorder. A journal Supplement in memory of Professor Maurizio Luisetti.

PMID: 25654654
Journal: COPD-Journal of Chronic Obstructive Pulmonary Disease
Year: 2015
Reference: COPD. 2015 Feb;12(1):1-2. doi: 10.3109/15412555.2015.1003463.
Impact factor: 2.673
Publication type: Paper in international publication
Authors: Brusasco, Vito, Miravitlles, Marc et al.
DOI: 10.3109/15412555.2015.1003463

ALSUntangled: Introducing The Table of Evidence.

PMID: 25544643
Journal: ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
Year: 2015
Reference: Amyotroph Lateral Scler Frontotemporal Degener. 2015 Mar;16(1-2):142-5. doi: 10.3109/21678421.2014.987476. Epub 2014 Dec 27.
Impact factor: 2.405
Publication type: Paper in international publication
Authors: Gamez Carbonell, Josep et al.
DOI: 10.3109/21678421.2014.987476

ALSUntangled No. 27: Precision Stem Cell.

PMID: 25807846
Journal: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Year: 2015
Reference: Amyotroph Lateral Scler Frontotemporal Degener. 2015 Jun;16(3-4):282-5. doi: 10.3109/21678421.2015.1024571. Epub 2015 Mar 26.
Impact factor: 2.405
Publication type: Paper in international publication
Authors: Forshew, Dallas, Carter, Gregory, Kabashi, Edor, Bertorini, Tulio, Mozaffar, Tahseen, Andersen, Peter, Dietz, Jeff, Gamez, Josep, Dimachkie, Mazen, Wang, Yunxia et al.
DOI: 10.3109/21678421.2015.1024571

ALSUntangled No. 28: Acupuncture.

PMID: 25960084
Journal: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Year: 2015
Reference: Amyotroph Lateral Scler Frontotemporal Degener. 2015 Jun;16(3-4):286-9. doi: 10.3109/21678421.2015.1039240. Epub 2015 May 11.
Impact factor: 2.405
Publication type: Paper in international publication
Authors: Phillips, Larry, Dimachkie, Mazen, Wang, Yunxia, Wicks, Paul, Heywood, James, Novella, Steven, Rowland, L P, Pioro, Erik, Kinsley, Lisa, Mitchell, Kathy et al.
DOI: 10.3109/21678421.2015.1039240

ALSUntangled No. 29: MitoQ.

PMID: 26090901
Journal: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Year: 2015
Reference: Amyotroph Lateral Scler Frontotemporal Degener. 2015;16(5-6):427-9. doi: 10.3109/21678421.2015.1050897. Epub 2015 Jun 19.
Impact factor: 2.405
Publication type: Paper in international publication
Authors: Nash, Steven, Rowland, L P, Pioro, Erik, Kinsley, Lisa, Mitchell, Kathy, Glass, Jonathan, Sathornsumetee, Sith, Kwiecinski, Hubert, Baker, Jon, Atassi, Nazem et al.
DOI: 10.3109/21678421.2015.1050897

ALSUntangled No. 30: methylcobalamin.

PMID: 26203660
Journal: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Year: 2015
Reference: Amyotroph Lateral Scler Frontotemporal Degener. 2015;16(7-8):536-9. doi: 10.3109/21678421.2015.1070574. Epub 2015 Jul 23.
Impact factor: 2.405
Publication type: Paper in international publication
Authors: Dietz, Jeff, Gamez, Josep, Dimachkie, Mazen, Wang, Yunxia, Wicks, Paul, Heywood, James, Novella, Steven, Rowland, L P, Pioro, Erik, Kinsley, Lisa et al.
DOI: 10.3109/21678421.2015.1070574

ALSUntangled No. 31: Protandim.

PMID: 26414415
Journal: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Year: 2015
Reference: Amyotroph Lateral Scler Frontotemporal Degener. 2015;17(1-2):154-6. doi: 10.3109/21678421.2015.1088707. Epub 2015 Sep 28.
Impact factor: 2.405
Publication type: Review in national publication
Authors: et al.
DOI: 10.3109/21678421.2015.1088707

Alterations in cerebral white matter and neuropsychology in patients with cirrhosis and falls.

PMID: 25793766
Journal: PLoS One
Year: 2015
Reference: PLoS One. 2015 Mar 20;10(3):e0118930. doi: 10.1371/journal.pone.0118930. eCollection 2015.
Impact factor: 3.234
Publication type: Paper in international publication
Authors: Nunez, Fidel, Gomez-Anson, Beatriz, Roman, Eva, Fernandez de Bobadilla, Ramon, Pires-Encuentra, Patricia, Diaz-Manera, Jordi, Pagonabarraga, Javier, Kulisevsky, Jaume, Cordoba, Juan, Guarner, Carlos et al.
DOI: 10.1371/journal.pone.0118930

Altered FoF1 ATP synthase and susceptibility to mitochondrial permeability transition pore during ischaemia and reperfusion in aging cardiomyocytes.

PMID: 25631625
Journal: THROMBOSIS AND HAEMOSTASIS
Year: 2015
Reference: Thromb Haemost. 2015 Mar;113(3):441-51. doi: 10.1160/TH14-10-0901. Epub 2015 Jan 29.
Impact factor: 4.984
Publication type: Paper in international publication
Authors: Castellano, Jose, Fernandez-Sanz, Celia, Ruiz-Meana, Marisol, Inserte, Javier, Vazquez, Jesus, Garcia-Dorado, David, Nunez, Estefania, Miro-Casas, Elisabet et al.
DOI: 10.1160/TH14-10-0901

Amyloid-beta reduces the expression of neuronal FAIM-L, thereby shifting the inflammatory response mediated by TNFalpha from neuronal protection to death.

PMID: 25675299
Journal: Cell Death & Disease
Year: 2015
Reference: Cell Death Dis. 2015 Feb 12;6:e1639. doi: 10.1038/cddis.2015.6.
Impact factor: 5.014
Publication type: Paper in international publication
Authors: Lopez-Soriano, J, Gutierrez, A, Vitorica, J, Comella, J X, Moubarak, R S, Barneda-Zahonero, B, Navarro, V, Carriba, P, Jimenez, S, Moreno-Gonzalez, I et al.
DOI: 10.1038/cddis.2015.6

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