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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Bleeding before prophylaxis in severe hemophilia: paradigm shift over two decades.

PMID: 25527565
Journal: HAEMATOLOGICA
Year: 2015
Reference: Haematologica. 2015 Mar;100(3):e84-6. doi: 10.3324/haematol.2014.115709. Epub 2014 Dec 19.
Impact factor: 5.814
Publication type: Letter whit IF
Authors: Nijdam, Annelies, Altisent, Carmen, Carcao, Manuel D, Cid, Ana R, Claeyssens-Donadel, Segolene, Kurnik, Karin, Ljung, Rolf, Nolan, Beatrice, Petrini, Pia, Platokouki, Helen et al.
DOI: 10.3324/haematol.2014.115709

Blockade of the SNARE protein syntaxin 1 inhibits glioblastoma tumor growth.

PMID: 25803850
Journal: PLoS One
Year: 2015
Reference: PLoS One. 2015 Mar 24;10(3):e0119707. doi: 10.1371/journal.pone.0119707. eCollection 2015.
Impact factor: 3.234
Publication type: Paper in international publication
Authors: Ulloa, Fausto, Gonzalez-Junca, Alba, Meffre, Delphine, Barrecheguren, Pablo Jose, Martinez-Marmol, Ramon, Pazos, Irene, Olive, Nuria, Cotrufo, Tiziana, Seoane, Joan, Soriano, Eduardo et al.
DOI: 10.1371/journal.pone.0119707

Blood PGC-1alpha Concentration Predicts Myocardial Salvage and Ventricular Remodeling After ST-segment Elevation Acute Myocardial Infarction.

PMID: 25440044
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2015
Reference: Rev Esp Cardiol (Engl Ed). 2015 May;68(5):408-16. doi: 10.1016/j.rec.2014.05.020. Epub 2014 Nov 5.
Impact factor: 3.342
Publication type: Paper in national publication
Authors: Monsalve, Maria, Mata, Manuel, Barrabes, Jose A, Berenguer-Jofresa, Alberto, Valle-Munoz, Alfonso, Fabregat-Andres, Oscar, Ridocci-Soriano, Francisco, Estornell-Erill, Jordi, Corbi-Pascual, Miguel et al.
DOI: 10.1016/j.rec.2014.05.020

[Body plethysmography (I): Standardisation and quality criteria].

PMID: 25797588
Journal: ANALES DE PEDIATRIA
Year: 2015
Reference: An Pediatr (Barc). 2015 Aug;83(2):136.e1-7. doi: 10.1016/j.anpedi.2014.10.029. Epub 2015 Mar 18.
Impact factor: 0.833
Publication type: Clinical guide
Authors: de Mir Messa, I, Sardon Prado, O, Larramona, H, Salcedo Posadas, A, Villa Asensi, J R et al.
DOI: 10.1016/j.anpedi.2014.10.029

Bosutinib shows low cross intolerance, in chronic myeloid leukemia patients treated in fourth line. Results of the Spanish compassionate use program.

PMID: 25683327
Journal: AMERICAN JOURNAL OF HEMATOLOGY
Year: 2015
Reference: Am J Hematol. 2015 May;90(5):429-33. doi: 10.1002/ajh.23973. Epub 2015 Mar 30.
Impact factor: 3.798
Publication type: Paper in international publication
Authors: Romero, Esperanza, Ortega, Fernando, Mata, Isabel, Tallon, Jose, Garcia Garay, Maria Del Carmen, Ramirez Sanchez, Maria Jose, de Las Heras, Natalia, Giraldo, Pilar, Bobillo, Sabela, Guinea, Jose Maria et al.
DOI: 10.1002/ajh.23973

BRAF mutation analysis in circulating free tumor DNA of melanoma patients treated with BRAF inhibitors.

PMID: 26366702
Journal: MELANOMA RESEARCH
Year: 2015
Reference: Melanoma Res. 2015 Dec;25(6):486-95. doi: 10.1097/CMR.0000000000000187.
Impact factor: 2.282
Publication type: Paper in international publication
Authors: Gonzalez-Cao, Maria, Mayo-de-Las-Casas, Clara, Molina-Vila, Miguel A, De Mattos-Arruda, Leticia, Munoz-Couselo, Eva, Manzano, Jose L, Cortes, Javier, Berros, Jose P, Drozdowskyj, Ana, Sanmamed, Miguel et al.
DOI: 10.1097/CMR.0000000000000187

Brain atrophy in natalizumab-treated patients: A 3-year follow-up.

PMID: 25392330
Journal: Multiple Sclerosis Journal
Year: 2015
Reference: Mult Scler. 2015 May;21(6):749-56. doi: 10.1177/1352458514556300. Epub 2014 Nov 12.
Impact factor: 4.863
Publication type: Paper in international publication
Authors: Rovira, A, Sastre-Garriga, J, Tur, C, Pareto, D, Vidal-Jordana, A, Auger, C, Rio, J, Huerga, E, Tintore, M, Montalban, X et al.
DOI: 10.1177/1352458514556300

Brain death organ donation potential and life support therapy limitation in neurocritical patients.

PMID: 25443330
Journal: Medicina Intensiva
Year: 2015
Reference: Med Intensiva. 2015 Aug-Sep;39(6):337-44. doi: 10.1016/j.medin.2014.07.010. Epub 2014 Oct 23.
Impact factor: 1.24
Publication type: Paper in national publication
Authors: Bodi, M A, Pont, T, Sandiumenge, A, Oliver, E, Gener, J, Badia, M, Mestre, J, Munoz, E, Esquirol, X, Llaurado, M et al.
DOI: 10.1016/j.medin.2014.07.010

Brain metabolite differences in one-year-old infants born small at term and association with neurodevelopmental outcome.

PMID: 25891998
Journal: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
Year: 2015
Reference: Am J Obstet Gynecol. 2015 Aug;213(2):210.e1-210.e11. doi: 10.1016/j.ajog.2015.04.011. Epub 2015 Apr 16.
Impact factor: 4.704
Publication type: Paper in international publication
Authors: Simoes, Rui V, Cruz-Lemini, Monica, Bargallo, Nuria, Gratacos, Eduard, Sanz-Cortes, Magdalena et al.
DOI: 10.1016/j.ajog.2015.04.011

Brain Microdialysis as a Tool To Explore the Ionic Profile of the Brain Extracellular Space in Neurocritical Patients: A Methodological Approach and Feasibility Study.

PMID: 25019674
Journal: JOURNAL OF NEUROTRAUMA
Year: 2015
Reference: J Neurotrauma. 2015 Jan 1;32(1):7-16. doi: 10.1089/neu.2014.3473.
Impact factor: 3.714
Publication type: Paper in international publication
Authors: Martinez-Valverde, Tamara, Vidal-Jorge, Marian, Montoya, Noelia, Sanchez-Guerrero, Angela, Manrique, Susana, Munar, Francisca, Pellegri, Maria-Dolors, Poca, Maria-Antonia, Sahuquillo, Juan et al.
DOI: 10.1089/neu.2014.3473

Brain perfusion and permeability in patients with advanced, refractory glioblastoma treated with lomustine and the transforming growth factor-beta receptor I kinase inhibitor LY2157299 monohydrate.

PMID: 26137087
Journal: Oncology Letters
Year: 2015
Reference: Oncol Lett. 2015 Jun;9(6):2442-2448. Epub 2015 Apr 8.
Impact factor: 1.554
Publication type: Paper in international publication
Authors: Sepulveda-Sanchez, Juan, Ramos, Ana, Hilario, Amaya, DE Velasco, Guillermo, Castellano, Daniel, Garcia DE LA Torre, Marta, Rodon, Jordi, Lahn, Michael F et al.
DOI: 10.3892/ol.2015.3106

Brainstem Auditory and Somatosensory Evoked Potentials in Relation to Clinical and Neuroimaging Findings in Chiari Type 1 Malformation.

PMID: 25275579
Journal: JOURNAL OF CLINICAL NEUROPHYSIOLOGY
Year: 2015
Reference: J Clin Neurophysiol. 2015 Apr;32(2):130-8. doi: 10.1097/WNP.0000000000000141.
Impact factor: 1.595
Publication type: Paper in international publication
Authors: Poca, Maria-Antonia, Minoves, Teresa, Ferre, Alejandro, Rahnama, Kimia, Sahuquillo, Juan, Moncho, Dulce et al.
DOI: 10.1097/WNP.0000000000000141

BRCA1 and BRCA2 mutations in males with familial breast and ovarian cancer syndrome. Results of a Spanish multicenter study.

PMID: 26026974
Journal: Familial Cancer
Year: 2015
Reference: Fam Cancer. 2015 Dec;14(4):505-13. doi: 10.1007/s10689-015-9814-z.
Impact factor: 1.977
Publication type: Paper in international publication
Authors: Diez, Orland, de Juan, Inmaculada, Palanca, Sarai, Domenech, Asuncion, Feliubadalo, Lidia, Segura, Angel, Osorio, Ana, Chirivella, Isabel, de la Hoya, Miguel, Sanchez, Ana Beatriz et al.
DOI: 10.1007/s10689-015-9814-z

Breast regression protein-39 is not required for experimental autoimmune encephalomyelitis induction.

PMID: 26079949
Journal: CLINICAL IMMUNOLOGY
Year: 2015
Reference: Clin Immunol. 2015 Oct;160(2):133-41. doi: 10.1016/j.clim.2015.06.004. Epub 2015 Jun 12.
Impact factor: 3.672
Publication type: Paper in international publication
Authors: Canto, Ester, Espejo, Carmen, Costa, Carme, Montalban, Xavier, Comabella, Manuel et al.
DOI: 10.1016/j.clim.2015.06.004

BRIP1 as an ovarian cancer susceptibility gene: ready for the clinic?

PMID: 26315355
Journal: JNCI-Journal of the National Cancer Institute
Year: 2015
Reference: J Natl Cancer Inst. 2015 Aug 27;107(11). pii: djv262. doi: 10.1093/jnci/djv262. Print 2015 Nov.
Impact factor: 12.583
Publication type: Editorail in international publication
Authors: Balmana, Judith, Domchek, Susan M et al.
DOI: 10.1093/jnci/djv262

Bronchiectasis: A retrospective study of clinical and aetiological investigation in a general respiratory department.

PMID: 25854129
Journal: Archives of Clinical Psychiatry
Year: 2015
Reference: Rev Port Pneumol (2006). 2015 Jan-Feb;21(1):5-10. doi: 10.1016/j.rppnen.2014.06.009. Epub 2015 Jan 22.
Impact factor: 1.167
Publication type: Paper in international publication
Authors: Amorim, A, Bento, J, Vaz, A P, Gomes, I, de Gracia, J, Hespanhol, V, Marques, A et al.
DOI: 10.1016/j.rppnen.2014.06.009

Brucellosis as a Primary Cause of Flexor Tenosynovitis on the Hand: Case Report and Literature Review.

PMID: 26078527
Journal: Journal of hand and microsurgery
Year: 2015
Reference: J Hand Microsurg. 2015 Jun;7(1):140-2. doi: 10.1007/s12593-014-0122-x. Epub 2014 Feb 20.
Impact factor: 0
Publication type: Paper in international publication
Authors: Lluch, Alex, Barrera-Ochoa, Sergi, Cortina, Josep, Mir-Bullo, Xavier et al.
DOI: 10.1007/s12593-014-0122-x

B-type natriuretic peptides help in cardioembolic stroke diagnosis: pooled data meta-analysis.

PMID: 25765726
Journal: STROKE
Year: 2015
Reference: Stroke. 2015 May;46(5):1187-95. doi: 10.1161/STROKEAHA.114.008311. Epub 2015 Mar 12.
Impact factor: 5.723
Publication type: Review in international publication
Authors: Etgen, Thorleif, Llombart, Victor, Antolin-Fontes, Albert, Bustamante, Alejandro, Giralt, Dolors, Rost, Natalia S, Furie, Karen, Shibazaki, Kensaku, Biteker, Murat, Castillo, Jose et al.
DOI: 10.1161/STROKEAHA.114.008311

Budgetary impact analysis on funding smoking-cessation drugs in patients with COPD in Spain.

PMID: 26451100
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2015
Reference: Int J Chron Obstruct Pulmon Dis. 2015 Sep 24;10:2027-36. doi: 10.2147/COPD.S87597. eCollection 2015.
Impact factor: 3.141
Publication type: Paper in international publication
Authors: Rejas, Javier, Oyaguez, Itziar, Jimenez-Ruiz, Carlos A, Solano-Reina, Segismundo, Signes-Costa, Jaime, de Higes-Martinez, Eva, Granda-Orive, Jose I, Lorza-Blasco, Jose J, Riesco-Miranda, Juan A, Altet-Gomez, Neus et al.
DOI: 10.2147/COPD.S87597

Buprenorphine-naloxone treatment in physicians and nurses with opioid dependence.

PMID: 25738533
Journal: Substance Abuse
Year: 2015
Reference: Subst Abus. 2015;36(2):138-40. doi: 10.1080/08897077.2014.996698.
Impact factor: 2.097
Publication type: Paper in international publication
Authors: Braquehais, Maria Dolores, Fadeuilhe, Christian, Hakansson, Anders, Bel, Miquel Jordi, Navarro, Maria Cecilia, Roncero, Carlos, Bruguera, Eugeni, Casas, Miquel et al.
DOI: 10.1080/08897077.2014.996698

Burden of serious fungal infections in Spain.

PMID: 25658565
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2015
Reference: Clin Microbiol Infect. 2015 Feb;21(2):183-9. doi: 10.1016/j.cmi.2014.07.013. Epub 2014 Oct 29.
Impact factor: 5.768
Publication type: Paper in international publication
Authors: Rodriguez-Tudela, J L, Alastruey-Izquierdo, A, Gago, S, Cuenca-Estrella, M, Leon, C, Miro, J M, Nunez Boluda, A, Ruiz Camps, I, Sole, A, Denning, D W et al.
DOI: 10.1016/j.cmi.2014.07.013

[Burnout and teamwork in primary care teams].

PMID: 24908347
Journal: Atencion Primaria
Year: 2015
Reference: Aten Primaria. 2015 Jan;47(1):25-31. doi: 10.1016/j.aprim.2014.01.008. Epub 2014 Jun 6.
Impact factor: 0.953
Publication type: Paper in national publication
Authors: Vila Falgueras, Maite, Cruzate Munoz, Carlota, Orfila Pernas, Francesc, Davins Miralles, Josep, Gonzalez Lopez, Maria Pilar, Creixell Sureda, Joan et al.
DOI: 10.1016/j.aprim.2014.01.008

Cabazitaxel Versus Topotecan in Patients with Small-Cell Lung Cancer with Progressive Disease During or After First-Line Platinum-Based Chemotherapy.

PMID: 26200278
Journal: Journal of Thoracic Oncology
Year: 2015
Reference: J Thorac Oncol. 2015 Aug;10(8):1221-8. doi: 10.1097/JTO.0000000000000588.
Impact factor: 5.282
Publication type: Paper in international publication
Authors: Evans, Tracey L, Cho, Byoung Chul, Udud, Katalin, Fischer, Juergen R, Shepherd, Frances A, Martinez, Pablo, Ramlau, Rodryg, Syrigos, Konstantinos N, Shen, Liji, Chadjaa, Mustapha et al.
DOI: 10.1097/JTO.0000000000000588

Candida infective endocarditis: an observational cohort study with a focus on therapy.

PMID: 25645855
Journal: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Year: 2015
Reference: Antimicrob Agents Chemother. 2015 Apr;59(4):2365-73. doi: 10.1128/AAC.04867-14. Epub 2015 Feb 2.
Impact factor: 4.476
Publication type: Paper in international publication
Authors: Arnold, Christopher J, Johnson, Melissa, Bayer, Arnold S, Bradley, Suzanne, Giannitsioti, Efthymia, Miro, Jose M, Tornos, Pilar, Tattevin, Pierre, Strahilevitz, Jacob, Spelman, Denis et al.
DOI: 10.1128/AAC.04867-14