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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Opportunistic testing of BRCA1, BRCA2 and mismatch repair genes improves the yield of phenotype driven hereditary cancer gene panels.

PMID: 30927264
Journal: INTERNATIONAL JOURNAL OF CANCER
Year: 2019
Reference: Int J Cancer. 2019 Nov 15;145(10):2682-2691. doi: 10.1002/ijc.32304. Epub 2019 Apr 15.
Impact factor: 4.982
Publication type: Paper in international publication
Authors: Feliubadalo, Lidia, Lopez-Fernandez, Adria, Pineda, Marta, Diez, Orland, Del Valle, Jesus, Gutierrez-Enriquez, Sara, Teule, Alex, Gonzalez, Sara, Stjepanovic, Neda, Salinas, Monica et al.
DOI: 10.1002/ijc.32304

Opportunistic testing of BRCA1, BRCA2 and mismatch repair genes improves the yield of phenotype driven hereditary cancer gene panels.

PMID: 30927264
Journal: INTERNATIONAL JOURNAL OF CANCER
Year: 2019
Reference: Int J Cancer. 2019 Nov 15;145(10):2682-2691. doi: 10.1002/ijc.32304. Epub 2019 Apr 15.
Impact factor:
Publication type: Paper in international publication
Authors: Balmana, Judith; Brunet, Joan; Capella, Gabriel; Del Valle, Jesus; Diez, Orland; Feliubadalo, Lidia; Gonzalez, Sara; Gutierrez-Enriquez, Sara; Lazaro, Conxi; Lopez-Fernandez, Adria et al.
DOI: 10.1002/ijc.32304

Opposite Effects of Moderate and Extreme Cx43 Deficiency in Conditional Cx43-Deficient Mice on Angiotensin II-Induced Cardiac Fibrosis.

PMID: 31652649
Journal: Cells
Year: 2019
Reference: Cells. 2019 Oct 22;8(10). pii: cells8101299. doi: 10.3390/cells8101299.
Impact factor: 5.656
Publication type: Paper in international publication
Authors: Valls-Lacalle, Laura, Negre-Pujol, Corall, Rodriguez, Cristina, Varona, Saray, Valera-Canellas, Antoni, Consegal, Marta, Martinez-Gonzalez, Jose, Rodriguez-Sinovas, Antonio et al.
DOI: 10.3390/cells8101299

Opposite Effects of Moderate and Extreme Cx43 Deficiency in Conditional Cx43-Deficient Mice on Angiotensin II-Induced Cardiac Fibrosis.

PMID: 31652649
Journal: Cells
Year: 2019
Reference: Cells. 2019 Oct 22;8(10). pii: cells8101299. doi: 10.3390/cells8101299.
Impact factor:
Publication type: Paper in international publication
Authors: Consegal, Marta; Martinez-Gonzalez, Jose; Negre-Pujol, Corall; Rodriguez, Cristina; Rodriguez-Sinovas, Antonio; Valera-Canellas, Antoni; Valls-Lacalle, Laura; Varona, Saray et al.
DOI: 10.3390/cells8101299

Optimal duration of treatment with eculizumab in atypical hemolytic uremic syndrome (aHUS)-a question to be addressed in a scientific way.

PMID: 30693384
Journal: PEDIATRIC NEPHROLOGY
Year: 2019
Reference: Pediatr Nephrol. 2019 May;34(5):943-949. doi: 10.1007/s00467-019-4192-7. Epub 2019 Jan 28.
Impact factor: 2.816
Publication type: Editorail in international publication
Authors: Ariceta, Gema et al.
DOI: 10.1007/s00467-019-4192-7

Optimal duration of treatment with eculizumab in atypical hemolytic uremic syndrome (aHUS)-a question to be addressed in a scientific way.

PMID: 30693384
Journal: PEDIATRIC NEPHROLOGY
Year: 2019
Reference: Pediatr Nephrol. 2019 May;34(5):943-949. doi: 10.1007/s00467-019-4192-7. Epub 2019 Jan 28.
Impact factor:
Publication type: Editorail in international publication
Authors: Ariceta, Gema et al.
DOI: 10.1007/s00467-019-4192-7

Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery.

PMID: 30647034
Journal: BMJ Open
Year: 2019
Reference: BMJ Open. 2019 Jan 15;9(1):e023455. doi: 10.1136/bmjopen-2018-023455.
Impact factor: 2.376
Publication type: Paper in international publication
Authors: Raj, Ashok, Pearse, Rupert M, Macdonald, Neil, Abbott, Tom, Martin, Tim, Januszewska, Marta, Niebrzegowska, Edyta, Bekele, Solana, Pates, Katherine, Haines, Ryan et al.
DOI: 10.1136/bmjopen-2018-023455

Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery.

PMID: 30647034
Journal: BMJ Open
Year: 2019
Reference: BMJ Open. 2019 Jan 15;9(1):e023455. doi: 10.1136/bmjopen-2018-023455.
Impact factor:
Publication type: Paper in international publication
Authors: Abad-Gurumeta, Alfredo; Abad-Motos, Ane; Abbott, Tom; Abdel-Nabi, Helen; Abukhudair, Hussein; Agarwal, Nipun; Ahmad, Nadeem; Alarcon, Maria Mercader; Aldecoa, Cesar; Aldecoa, Cesar et al.
DOI: 10.1136/bmjopen-2018-023455

Optimisation of the use of APRI and FIB-4 to rule out cirrhosis in patients with chronic hepatitis B: results from the SONIC-B study.

PMID: 30975477
Journal: Lancet Gastroenterology & Hepatology
Year: 2019
Reference: Lancet Gastroenterol Hepatol. 2019 Jul;4(7):538-544. doi: 10.1016/S2468-1253(19)30087-1. Epub 2019 Apr 9.
Impact factor: 12.856
Publication type: Paper in international publication
Authors: Chan, Henry L-Y, Sonneveld, Milan J, Brouwer, Willem P, Zeuzem, Stefan, Liaw, Yun-Fan, Hansen, Bettina E, Choi, Hannah, Wat, Cynthia, Pavlovic, Vedran, Gaggar, Anuj et al.
DOI: 10.1016/S2468-1253(19)30087-1

Optimisation of the use of APRI and FIB-4 to rule out cirrhosis in patients with chronic hepatitis B: results from the SONIC-B study.

PMID: 30975477
Journal: Lancet Gastroenterology & Hepatology
Year: 2019
Reference: Lancet Gastroenterol Hepatol. 2019 Jul;4(7):538-544. doi: 10.1016/S2468-1253(19)30087-1. Epub 2019 Apr 9.
Impact factor:
Publication type: Paper in international publication
Authors: Brouwer, Willem P; Buti, Maria; Chan, Henry L-Y; Choi, Hannah; de Knegt, Robert J; Gaggar, Anuj; Hansen, Bettina E; Janssen, Harry L A; Jia, Ji-Dong; Liaw, Yun-Fan et al.
DOI: 10.1016/S2468-1253(19)30087-1

Optimization of surgical treatment of advanced ovarian cancer: a Spanish expert perspective.

PMID: 30377941
Journal: Clinical & Translational Oncology
Year: 2019
Reference: Clin Transl Oncol. 2019 May;21(5):656-664. doi: 10.1007/s12094-018-1967-4. Epub 2018 Oct 30.
Impact factor: 2.441
Publication type: Paper in international publication
Authors: Chiva, L, Rodriguez-Garzotto, A, Gil-Moreno, A, Minig, L, de Santiago, J, Domingo, S, Martinez, S et al.
DOI: 10.1007/s12094-018-1967-4

Optimization of surgical treatment of advanced ovarian cancer: a Spanish expert perspective.

PMID: 30377941
Journal: Clinical & Translational Oncology
Year: 2019
Reference: Clin Transl Oncol. 2019 May;21(5):656-664. doi: 10.1007/s12094-018-1967-4. Epub 2018 Oct 30.
Impact factor:
Publication type: Paper in international publication
Authors: Chiva, L; de Santiago, J; Domingo, S; Gil-Moreno, A; Martinez, S; Minig, L; Rodriguez-Garzotto, A et al.
DOI: 10.1007/s12094-018-1967-4

Optimization of the neurosurgical patient in Intensive Care.

PMID: 30982626
Journal: Medicina Intensiva
Year: 2019
Reference: Med Intensiva. 2019 Nov;43(8):489-496. doi: 10.1016/j.medin.2019.02.011. Epub 2019 Apr 11.
Impact factor: 1.982
Publication type: Paper in national publication
Authors: Arikan Abello, F, Sanchez Corral, A, Ferrer Roca, R, Santafe Colomina, M et al.
DOI: 10.1016/j.medin.2019.02.011

Optimization of the neurosurgical patient in Intensive Care.

PMID: 30982626
Journal: Medicina Intensiva
Year: 2019
Reference: Med Intensiva. 2019 Nov;43(8):489-496. doi: 10.1016/j.medin.2019.02.011. Epub 2019 Apr 11.
Impact factor:
Publication type: Paper in national publication
Authors: Arikan Abello, F; Ferrer Roca, R; Sanchez Corral, A; Santafe Colomina, M et al.
DOI: 10.1016/j.medin.2019.02.011

Optimization of the Therapeutic Approach to Patients with Sarcoma: Delphi Consensus.

PMID: 31975783
Journal: Sarcoma
Year: 2019
Reference: Sarcoma. 2019 Dec 26;2019:4351308. doi: 10.1155/2019/4351308. eCollection 2019.
Impact factor: 0
Publication type: Review in international publication
Authors: Lopez Pousa, Antonio, Martin-Broto, Javier, Valverde, Claudia Maria, Giner, Javier Lavernia, Del Muro Solans, Xavier Garcia, Cruz Jurado, Josefina, Alvarez Alvarez, Rosa et al.
DOI: 10.1155/2019/4351308

Optimization of the Therapeutic Approach to Patients with Sarcoma: Delphi Consensus.

PMID: 31975783
Journal: Sarcoma
Year: 2019
Reference: Sarcoma. 2019 Dec 26;2019:4351308. doi: 10.1155/2019/4351308. eCollection 2019.
Impact factor:
Publication type: Review in international publication
Authors: Alvarez Alvarez, Rosa; Cruz Jurado, Josefina; Del Muro Solans, Xavier Garcia; Giner, Javier Lavernia; Lopez Pousa, Antonio; Martin-Broto, Javier; Valverde, Claudia Maria et al.
DOI: 10.1155/2019/4351308

Optimization of Transbronchial Cryobiopsy in Lung Transplant Recipients.

PMID: 31229481
Journal: ANNALS OF THORACIC SURGERY
Year: 2019
Reference: Ann Thorac Surg. 2019 Oct;108(4):1052-1058. doi: 10.1016/j.athoracsur.2019.04.096. Epub 2019 Jun 21.
Impact factor: 3.919
Publication type: Paper in international publication
Authors: Loor, Karina, Culebras, Mario, Sansano, Irene, Alvarez, Antonio, Berastegui, Cristina, de Gracia, Javier et al.
DOI: 10.1016/j.athoracsur.2019.04.096

Optimization of Transbronchial Cryobiopsy in Lung Transplant Recipients.

PMID: 31229481
Journal: ANNALS OF THORACIC SURGERY
Year: 2019
Reference: Ann Thorac Surg. 2019 Oct;108(4):1052-1058. doi: 10.1016/j.athoracsur.2019.04.096. Epub 2019 Jun 21.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez, Antonio; Berastegui, Cristina; Culebras, Mario; de Gracia, Javier; Loor, Karina; Loor, Karina; Sansano, Irene et al.
DOI: 10.1016/j.athoracsur.2019.04.096

Optimizing the management of locally advanced pancreatic cancer with a focus on induction chemotherapy: Expert opinion based on a review of current evidence.

PMID: 31163334
Journal: CANCER TREATMENT REVIEWS
Year: 2019
Reference: Cancer Treat Rev. 2019 Jul;77:1-10. doi: 10.1016/j.ctrv.2019.05.007. Epub 2019 May 29.
Impact factor: 8.332
Publication type: Review in international publication
Authors: Seufferlein, Thomas, Hammel, Pascal, Delpero, Jean Robert, Macarulla, Teresa, Pfeiffer, Per, Prager, Gerald W, Reni, Michele, Falconi, Massimo, Philip, Philip A, Van Cutsem, Eric et al.
DOI: 10.1016/j.ctrv.2019.05.007

Optimizing the management of locally advanced pancreatic cancer with a focus on induction chemotherapy: Expert opinion based on a review of current evidence.

PMID: 31163334
Journal: CANCER TREATMENT REVIEWS
Year: 2019
Reference: Cancer Treat Rev. 2019 Jul;77:1-10. doi: 10.1016/j.ctrv.2019.05.007. Epub 2019 May 29.
Impact factor:
Publication type: Review in international publication
Authors: Delpero, Jean Robert; Falconi, Massimo; Hammel, Pascal; Macarulla, Teresa; Pfeiffer, Per; Philip, Philip A; Prager, Gerald W; Reni, Michele; Seufferlein, Thomas; Van Cutsem, Eric et al.
DOI: 10.1016/j.ctrv.2019.05.007

Oral metronomic vinorelbine combined with endocrine therapy in hormone receptor-positive HER2-negative breast cancer: SOLTI-1501 VENTANA window of opportunity trial.

PMID: 31533777
Journal: BREAST CANCER RESEARCH
Year: 2019
Reference: Breast Cancer Res. 2019 Sep 18;21(1):108. doi: 10.1186/s13058-019-1195-z.
Impact factor: 5.676
Publication type: Paper in international publication
Authors: Amillano, Kepa, Adamo, Barbara, Bellet, Meritxell, Pare, Laia, Pascual, Tomas, Vidal, Maria, Perez Fidalgo, Jose A, Blanch, Salvador, Martinez, Noelia, Murillo, Laura et al.
DOI: 10.1186/s13058-019-1195-z

Oral metronomic vinorelbine combined with endocrine therapy in hormone receptor-positive HER2-negative breast cancer: SOLTI-1501 VENTANA window of opportunity trial.

PMID: 31533777
Journal: BREAST CANCER RESEARCH
Year: 2019
Reference: Breast Cancer Res. 2019 Sep 18;21(1):108. doi: 10.1186/s13058-019-1195-z.
Impact factor:
Publication type: Paper in international publication
Authors: Adamo, Barbara; Amillano, Kepa; Bellet, Meritxell; Blanch, Salvador; Canes, Jordi; Ciruelos, Eva; Galvan, Patricia; Gomez-Pardo, Patricia; Gonzalez, Xavier; Gonzalez-Farre, Blanca et al.
DOI: 10.1186/s13058-019-1195-z

Origins of DNA methylation defects in Wilms tumors.

PMID: 31103718
Journal: CANCER LETTERS
Year: 2019
Reference: Cancer Lett. 2019 Aug 10;457:119-128. doi: 10.1016/j.canlet.2019.05.013. Epub 2019 May 16.
Impact factor: 6.508
Publication type: Paper in international publication
Authors: Anvar, Zahra, Acurzio, Basilia, Roma, Josep, Cerrato, Flavia, Verde, Gaetano et al.
DOI: 10.1016/j.canlet.2019.05.013

Origins of DNA methylation defects in Wilms tumors.

PMID: 31103718
Journal: CANCER LETTERS
Year: 2019
Reference: Cancer Lett. 2019 Aug 10;457:119-128. doi: 10.1016/j.canlet.2019.05.013. Epub 2019 May 16.
Impact factor:
Publication type: Paper in international publication
Authors: Acurzio, Basilia; Anvar, Zahra; Cerrato, Flavia; Roma, Josep; Verde, Gaetano et al.
DOI: 10.1016/j.canlet.2019.05.013