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The science produced by our scientists is very important. In 2024, 1,501 papers were published in scientific journals with an average impact factor of over 7.13 points.

Safety and effectiveness of low-dose amikacin in nontuberculous mycobacterial pulmonary disease treated in Toronto, Canada.

PMID: 31159865
Journal: BMC Pharmacology & Toxicology
Year: 2019
Reference: BMC Pharmacol Toxicol. 2019 Jun 3;20(1):37. doi: 10.1186/s40360-019-0302-1.
Impact factor:
Publication type: Paper in international publication
Authors: Aznar, Maria Luisa; Brode, Sarah K; Elshal, Ahmed Said; Marras, Theodore K; Mehrabi, Mahtab et al.
DOI: 10.1186/s40360-019-0302-1

Safety and effectiveness of sodium colistimethate-loaded nanostructured lipid carriers (SCM-NLC) against P. aeruginosa: in vitro and in vivo studies following pulmonary and intramuscular administration.

PMID: 30849549
Journal: Nanomedicine-Nanotechnology Biology and Medicine
Year: 2019
Reference: Nanomedicine. 2019 Jun;18:101-111. doi: 10.1016/j.nano.2019.02.014. Epub 2019 Mar 6.
Impact factor: 5.57
Publication type: Paper in international publication
Authors: Aguirre, J J, Esquisabel, A, Igartua, M, Gainza, E, Hernandez, R M, Gavalda, J, Pedraz, J L, Gutierrez, F B, Bachiller, D, Fleischer, A et al.
DOI: 10.1016/j.nano.2019.02.014

Safety and effectiveness of sodium colistimethate-loaded nanostructured lipid carriers (SCM-NLC) against P. aeruginosa: in vitro and in vivo studies following pulmonary and intramuscular administration.

PMID: 30849549
Journal: Nanomedicine-Nanotechnology Biology and Medicine
Year: 2019
Reference: Nanomedicine. 2019 Jun;18:101-111. doi: 10.1016/j.nano.2019.02.014. Epub 2019 Mar 6.
Impact factor:
Publication type: Paper in international publication
Authors: Aguirre, J J; Bachiller, D; Basas, J; Esquisabel, A; Fleischer, A; Gainza, E; Gainza, G; Gavalda, J; Gomis, X; Gutierrez, F B et al.
DOI: 10.1016/j.nano.2019.02.014

Safety and efficacy of bosutinib in fourth-line therapy of chronic myeloid leukemia patients.

PMID: 30446802
Journal: ANNALS OF HEMATOLOGY
Year: 2019
Reference: Ann Hematol. 2019 Feb;98(2):321-330. doi: 10.1007/s00277-018-3507-2. Epub 2018 Nov 16.
Impact factor: 2.85
Publication type: Paper in international publication
Authors: Claudiani, Simone, Garcia-Gutierrez, Valentin, Milojkovic, Dragana, Hernandez-Boluda, Juan Carlos, Ramirez, Maria Jose, Romero, Esperanza, Romo, Andres, Rosell, Ana, Saavedra, Silvanna Saavedra, Sebrango, Ana et al.
DOI: 10.1007/s00277-018-3507-2

Safety and efficacy of bosutinib in fourth-line therapy of chronic myeloid leukemia patients.

PMID: 30446802
Journal: ANNALS OF HEMATOLOGY
Year: 2019
Reference: Ann Hematol. 2019 Feb;98(2):321-330. doi: 10.1007/s00277-018-3507-2. Epub 2018 Nov 16.
Impact factor:
Publication type: Paper in international publication
Authors: Amustio Diez, Elena; Boque, Concepcion; Carrascosa, Guiomar Bautista; Casado-Montero, Luis Felipe; Claudiani, Simone; De Las Heras Rodriguez, Natalia; Del Carmen Garcia Garay, Maria; Fernandez, Maria Angeles; Garcia, Abelardo Barez; Garcia-Gutierrez, Valentin et al.
DOI: 10.1007/s00277-018-3507-2

Safety and efficacy of crizotinib in patients with advanced or metastatic ROS1-rearranged lung cancer (EUCROSS): A European phase 2 clinical trial.

PMID: 30978502
Journal: Journal of Thoracic Oncology
Year: 2019
Reference: J Thorac Oncol. 2019 Jul;14(7):1266-1276. doi: 10.1016/j.jtho.2019.03.020. Epub 2019 Apr 9.
Impact factor: 12.46
Publication type: Paper in international publication
Authors: Schildhaus, Hans-Ulrich, Franklin, Jeremy, Sebastian, Martin, Felip, Enriqueta, Grohe, Christian, Rodriguez-Abreu, Delvys, Abdulla, Diana S Y, Bischoff, Helge, Brandts, Christian, Carcereny, Enric et al.
DOI: 10.1016/j.jtho.2019.03.020

Safety and efficacy of crizotinib in patients with advanced or metastatic ROS1-rearranged lung cancer (EUCROSS): A European phase 2 clinical trial.

PMID: 30978502
Journal: Journal of Thoracic Oncology
Year: 2019
Reference: J Thorac Oncol. 2019 Jul;14(7):1266-1276. doi: 10.1016/j.jtho.2019.03.020. Epub 2019 Apr 9.
Impact factor:
Publication type: Paper in international publication
Authors: Abdulla, Diana S Y; Bischoff, Helge; Brandts, Christian; Buttner, Reinhard; Carcereny, Enric; Corral, Jesus; Dingemans, Anne-Marie C; Fassunke, Jana; Felip, Enriqueta; Fischer, Rieke N et al.
DOI: 10.1016/j.jtho.2019.03.020

Safety and Efficacy of Durvalumab With or Without Tremelimumab in Patients With PD-L1-Low/Negative Recurrent or Metastatic HNSCC: The Phase 2 CONDOR Randomized Clinical Trial.

PMID: 30383184
Journal: JAMA Oncology
Year: 2019
Reference: JAMA Oncol. 2019 Feb 1;5(2):195-203. doi: 10.1001/jamaoncol.2018.4628.
Impact factor: 22.416
Publication type: Paper in international publication
Authors: Mesia, Ricard, Siu, Lillian L, Even, Caroline, Delord, Jean-Pierre, Krauss, Jurgen, Saba, Nabil F, Nabell, Lisle, Ready, Neal E, Brana, Irene, Kotecki, Nuria et al.
DOI: 10.1001/jamaoncol.2018.4628

Safety and Efficacy of Durvalumab With or Without Tremelimumab in Patients With PD-L1-Low/Negative Recurrent or Metastatic HNSCC: The Phase 2 CONDOR Randomized Clinical Trial.

PMID: 30383184
Journal: JAMA Oncology
Year: 2019
Reference: JAMA Oncol. 2019 Feb 1;5(2):195-203. doi: 10.1001/jamaoncol.2018.4628.
Impact factor:
Publication type: Paper in international publication
Authors: Armstrong, Jon M; Bonomi, Marcelo; Brana, Irene; Daste, Amaury; Delord, Jean-Pierre; Even, Caroline; Fayette, Jerome; Gilbert, Jill; Jarkowski, Anthony; Kotecki, Nuria et al.
DOI: 10.1001/jamaoncol.2018.4628

Safety and efficacy of nivolumab in challenging subgroups with advanced melanoma who progressed on or after ipilimumab treatment: A single-arm, open-label, phase II study (CheckMate 172).

PMID: 31581055
Journal: EUROPEAN JOURNAL OF CANCER
Year: 2019
Reference: Eur J Cancer. 2019 Nov;121:144-153. doi: 10.1016/j.ejca.2019.08.014. Epub 2019 Sep 30.
Impact factor: 6.68
Publication type: Paper in international publication
Authors: Hoeller, Christoph, Schadendorf, Dirk, Ascierto, Paolo A, Haanen, John, Espinosa, Enrique, Demidov, Lev, Garbe, Claus, Guida, Michele, Lorigan, Paul, Chiarion-Sileni, Vanna et al.
DOI: 10.1016/j.ejca.2019.08.014

Safety and efficacy of nivolumab in challenging subgroups with advanced melanoma who progressed on or after ipilimumab treatment: A single-arm, open-label, phase II study (CheckMate 172).

PMID: 31581055
Journal: EUROPEAN JOURNAL OF CANCER
Year: 2019
Reference: Eur J Cancer. 2019 Nov;121:144-153. doi: 10.1016/j.ejca.2019.08.014. Epub 2019 Sep 30.
Impact factor:
Publication type: Paper in international publication
Authors: Ascierto, Paolo A; Bafaloukos, Dimitrios; Chiarion-Sileni, Vanna; Demidov, Lev; Dummer, Reinhard; Espinosa, Enrique; Fierro, Maria Teresa; Garbe, Claus; Gogas, Helen; Grigoryeva, Elena et al.
DOI: 10.1016/j.ejca.2019.08.014

Safety and efficacy of nivolumab in patients with rare melanoma subtypes who progressed on or after ipilimumab treatment: a single-arm, open-label, phase II study (CheckMate 172).

PMID: 31445199
Journal: EUROPEAN JOURNAL OF CANCER
Year: 2019
Reference: Eur J Cancer. 2019 Sep;119:168-178. doi: 10.1016/j.ejca.2019.07.010. Epub 2019 Aug 21.
Impact factor: 6.68
Publication type: Paper in international publication
Authors: Gutzmer, Ralf, Nathan, Paul, Ascierto, Paolo A, Haanen, John, Espinosa, Enrique, Demidov, Lev, Garbe, Claus, Guida, Michele, Lorigan, Paul, Chiarion-Sileni, Vanna et al.
DOI: 10.1016/j.ejca.2019.07.010

Safety and efficacy of nivolumab in patients with rare melanoma subtypes who progressed on or after ipilimumab treatment: a single-arm, open-label, phase II study (CheckMate 172).

PMID: 31445199
Journal: EUROPEAN JOURNAL OF CANCER
Year: 2019
Reference: Eur J Cancer. 2019 Sep;119:168-178. doi: 10.1016/j.ejca.2019.07.010. Epub 2019 Aug 21.
Impact factor:
Publication type: Paper in international publication
Authors: Ascierto, Paolo A; Bafaloukos, Dimitrios; Chiarion-Sileni, Vanna; Demidov, Lev; Dummer, Reinhard; Espinosa, Enrique; Fierro, Maria Teresa; Garbe, Claus; Gogas, Helen; Grigoryeva, Elena et al.
DOI: 10.1016/j.ejca.2019.07.010

Safety and Efficacy of Nivolumab Monotherapy in Recurrent or Metastatic Cervical, Vaginal, or Vulvar Carcinoma: Results From the Phase I/II CheckMate 358 Trial.

PMID: 31487218
Journal: JOURNAL OF CLINICAL ONCOLOGY
Year: 2019
Reference: J Clin Oncol. 2019 Nov 1;37(31):2825-2834. doi: 10.1200/JCO.19.00739. Epub 2019 Sep 5.
Impact factor: 28.245
Publication type: Paper in international publication
Authors: Naumann, R Wendel, Hollebecque, Antoine, Meyer, Tim, Devlin, Michael-John, Oaknin, Ana, Kerger, Joseph, Lopez-Picazo, Jose M, Machiels, Jean-Pascal, Delord, Jean-Pierre, Evans, Thomas R J et al.
DOI: 10.1200/JCO.19.00739

Safety and Efficacy of Nivolumab Monotherapy in Recurrent or Metastatic Cervical, Vaginal, or Vulvar Carcinoma: Results From the Phase I/II CheckMate 358 Trial.

PMID: 31487218
Journal: JOURNAL OF CLINICAL ONCOLOGY
Year: 2019
Reference: J Clin Oncol. 2019 Nov 1;37(31):2825-2834. doi: 10.1200/JCO.19.00739. Epub 2019 Sep 5.
Impact factor:
Publication type: Paper in international publication
Authors: Boni, Valentina; Calvo, Emiliano; Chen, Tian; Delord, Jean-Pierre; Devlin, Michael-John; Evans, Thomas R J; Gu, Junchen; Hollebecque, Antoine; Kerger, Joseph; Li, Bin et al.
DOI: 10.1200/JCO.19.00739

Safety and efficacy of opicinumab in patients with relapsing multiple sclerosis (SYNERGY): a randomised, placebo-controlled, phase 2 trial.

PMID: 31285147
Journal: LANCET NEUROLOGY
Year: 2019
Reference: Lancet Neurol. 2019 Sep;18(9):845-856. doi: 10.1016/S1474-4422(19)30137-1. Epub 2019 Jul 5.
Impact factor: 28.755
Publication type: Paper in international publication
Authors: Rudick, Richard, Cadavid, Diego, Mellion, Michelle, Hupperts, Raymond, Edwards, Keith R, Calabresi, Peter A, Drulovic, Jelena, Giovannoni, Gavin, Hartung, Hans-Peter, Arnold, Douglas L et al.
DOI: 10.1016/S1474-4422(19)30137-1

Safety and efficacy of opicinumab in patients with relapsing multiple sclerosis (SYNERGY): a randomised, placebo-controlled, phase 2 trial.

PMID: 31285147
Journal: LANCET NEUROLOGY
Year: 2019
Reference: Lancet Neurol. 2019 Sep;18(9):845-856. doi: 10.1016/S1474-4422(19)30137-1. Epub 2019 Jul 5.
Impact factor:
Publication type: Paper in international publication
Authors: Aguera Morales, Eduardo; Al Khedr, Abdullatif; Ampapa, Radek; Arnold, Douglas L; Arroyo, Rafael; Belkin, Martin; Bonek, Robert; Boyko, Alexey; Cadavid, Diego; Calabresi, Peter A et al.
DOI: 10.1016/S1474-4422(19)30137-1

Safety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (RADIANCE): a multicentre, randomised, 24-month, phase 3 trial.

PMID: 31492652
Journal: LANCET NEUROLOGY
Year: 2019
Reference: Lancet Neurol. 2019 Nov;18(11):1021-1033. doi: 10.1016/S1474-4422(19)30238-8. Epub 2019 Sep 3.
Impact factor: 28.755
Publication type: Paper in international publication
Authors: Cohen, Jeffrey A, Comi, Giancarlo, Selmaj, Krzysztof W, Bar-Or, Amit, Arnold, Douglas L, Steinman, Lawrence, Hartung, Hans-Peter, Montalban, Xavier, Kubala Havrdova, Eva, Cree, Bruce A C et al.
DOI: 10.1016/S1474-4422(19)30238-8

Safety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (RADIANCE): a multicentre, randomised, 24-month, phase 3 trial.

PMID: 31492652
Journal: LANCET NEUROLOGY
Year: 2019
Reference: Lancet Neurol. 2019 Nov;18(11):1021-1033. doi: 10.1016/S1474-4422(19)30238-8. Epub 2019 Sep 3.
Impact factor:
Publication type: Paper in international publication
Authors: Arnold, Douglas L; Bar-Or, Amit; Cohen, Jeffrey A; Comi, Giancarlo; Cree, Bruce A C; Hartung, Hans-Peter; Huang, Vivian; Kappos, Ludwig; Kubala Havrdova, Eva; Minton, Neil et al.
DOI: 10.1016/S1474-4422(19)30238-8

Safety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (SUNBEAM): a multicentre, randomised, minimum 12-month, phase 3 trial.

PMID: 31492651
Journal: LANCET NEUROLOGY
Year: 2019
Reference: Lancet Neurol. 2019 Nov;18(11):1009-1020. doi: 10.1016/S1474-4422(19)30239-X. Epub 2019 Sep 3.
Impact factor: 28.755
Publication type: Paper in international publication
Authors: Cree, Bruce A C, Sheffield, James K, Minton, Neil, Raghupathi, Kartik, Ding, Ning, Cohen, Jeffrey A, Kubala Havrdova, Eva, Montalban, Xavier, Steinman, Lawrence, Comi, Giancarlo et al.
DOI: 10.1016/S1474-4422(19)30239-X

Safety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (SUNBEAM): a multicentre, randomised, minimum 12-month, phase 3 trial.

PMID: 31492651
Journal: LANCET NEUROLOGY
Year: 2019
Reference: Lancet Neurol. 2019 Nov;18(11):1009-1020. doi: 10.1016/S1474-4422(19)30239-X. Epub 2019 Sep 3.
Impact factor:
Publication type: Paper in international publication
Authors: Arnold, Douglas L; Bar-Or, Amit; Cohen, Jeffrey A; Comi, Giancarlo; Cree, Bruce A C; Ding, Ning; Hartung, Hans-Peter; Kappos, Ludwig; Kubala Havrdova, Eva; Minton, Neil et al.
DOI: 10.1016/S1474-4422(19)30239-X

Safety and efficacy of pembrolizumab monotherapy in elderly patients with PD-L1-positive advanced non-small-cell lung cancer: Pooled analysis from the KEYNOTE-010, KEYNOTE-024, and KEYNOTE-042 studies.

PMID: 31446994
Journal: LUNG CANCER
Year: 2019
Reference: Lung Cancer. 2019 Sep;135:188-195. doi: 10.1016/j.lungcan.2019.07.004. Epub 2019 Jul 8.
Impact factor: 4.599
Publication type: Paper in international publication
Authors: Nosaki, Kaname, Saka, Hideo, Hosomi, Yukio, Baas, Paul, de Castro, Gilberto Jr, Reck, Martin, Wu, Yi-Long, Brahmer, Julie R, Felip, Enriqueta, Sawada, Takeshi et al.
DOI: 10.1016/j.lungcan.2019.07.004

Safety and efficacy of pembrolizumab monotherapy in elderly patients with PD-L1-positive advanced non-small-cell lung cancer: Pooled analysis from the KEYNOTE-010, KEYNOTE-024, and KEYNOTE-042 studies.

PMID: 31446994
Journal: LUNG CANCER
Year: 2019
Reference: Lung Cancer. 2019 Sep;135:188-195. doi: 10.1016/j.lungcan.2019.07.004. Epub 2019 Jul 8.
Impact factor:
Publication type: Paper in international publication
Authors: Baas, Paul; Brahmer, Julie R; de Castro, Gilberto Jr; Felip, Enriqueta; Han, Shi Rong; Hosomi, Yukio; Kush, Debra A; Lopes, Gilberto; Noguchi, Kazuo; Nosaki, Kaname et al.
DOI: 10.1016/j.lungcan.2019.07.004

Safety and efficacy of prolonged use of dalbavancin in bone and joint infections.

PMID: 30858217
Journal: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Year: 2019
Reference: Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: AAC.02280-18. doi: 10.1128/AAC.02280-18. Print 2019 May.
Impact factor: 4.715
Publication type: Paper in international publication
Authors: Arroyo, A, Barbero, J M, Cuadra, F, Del Arco, A, Del Toro, M D, Guio, L, Jimenez-Beatty, D, Lois, N, Martin, O, Martinez Alvarez, R M et al.
DOI: 10.1128/AAC.02280-18