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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

PAI-1 4G/5G polymorphism is associated with brain vessel reocclusion after successful fibrinolytic therapy in ischemic stroke patients.

PMID: 20374070
Journal: INTERNATIONAL JOURNAL OF NEUROSCIENCE
Year: 2010
Reference: Int J Neurosci. 2010 Apr;120(4):245-51.
Impact factor: 0.855
Publication type: Paper in international publication
Authors: Molina, C A, Fernandez-Cadenas, I, Del Rio-Espinola, A, Rubiera, M, Mendioroz, M, Domingues-Montanari, S, Cuadrado, E, Hernandez-Guillamon, M, Rosell, A, Ribo, M et al.
DOI: 10.3109/00207451003597169

[Pandemic influenza A (H1N1)v in the intensive care unit: what have we learned?]

PMID: 20353856
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2010
Reference: Arch Bronconeumol. 2010;46S2:24-31.
Impact factor: 2.166
Publication type: Paper in national publication
Authors: , , et al.
DOI: 10.1016/S0300-2896(10)70017-X

[Pandemic influenza A in the ICU: experience in Spain and Latin America. GETGAG/SEMICYUC/(Spanish Working Group on Severe Pandemic Influenza A/SEMICYUC)].

PMID: 20061066
Journal: Medicina Intensiva
Year: 2010
Reference: Med Intensiva. 2010 Mar;34(2):87-94. Epub 2010 Jan 12.
Impact factor:
Publication type: Letter or abstract
Authors: Rello, J, Rodriguez, A, Socias, L, Guerrero, J E, Figueira, J C, Gonzalez, N, Maravi-Poma, E, Lorente, L, Martin, M, Albaya-Moreno, A et al.
DOI: 10.1016/j.medin.2009.12.005

Panitumumab - an effective long-term treatment for patients with metastatic colorectal cancer and wild-type KRAS status.

PMID: 20189055
Journal: CANCER TREATMENT REVIEWS
Year: 2010
Reference: Cancer Treat Rev. 2010 Feb;36 Suppl 1:S15-6.
Impact factor: 5.295
Publication type: Editorail in international publication
Authors: Elez, Elena, Alsina, Maria, Tabernero, Josep et al.
DOI: 10.1016/S0305-7372(10)70003-7

Parity and the risk of breast and ovarian cancer in BRCA1 and BRCA2 mutation carriers.

PMID: 19370414
Journal: BREAST CANCER RESEARCH AND TREATMENT
Year: 2010
Reference: Breast Cancer Res Treat. 2010 Jan;119(1):221-32. Epub 2009 Apr 16.
Impact factor: 4.696
Publication type: Paper in international publication
Authors: Milne, Roger L, Osorio, Ana, Ramon y Cajal, Teresa, Baiget, Montserrat, Lasa, Adriana, Diaz-Rubio, Eduardo, de la Hoya, Miguel, Caldes, Trinidad, Teule, Alex, Lazaro, Conxi et al.
DOI: 10.1007/s10549-009-0394-1

Paroxysmal exercise-induced dyskinesia, writer's cramp, migraine with aura and absence epilepsy in twin brothers with a novel SLC2A1 missense mutation.

PMID: 20621801
Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES
Year: 2010
Reference: J Neurol Sci. 2010 Aug 15;295(1-2):110-3. Epub 2010 Jun 8.
Impact factor: 2.324
Publication type: Paper in international publication
Authors: Urbizu, Aintzane, Cuenca-Leon, Ester, Raspall-Chaure, Miquel, Gratacos, Margarida, Conill, Joan, Redecillas, Susana, Roig-Quilis, Manuel, Macaya, Alfons et al.
DOI: 10.1016/j.jns.2010.05.017

Partial 7q11.23 deletions further implicate GTF2I and GTF2IRD1 as the main genes responsible for the Williams-Beuren syndrome neurocognitive profile.

PMID: 19897463
Journal: JOURNAL OF MEDICAL GENETICS
Year: 2010
Reference: J Med Genet. 2010 May;47(5):312-20. Epub 2009 Nov 5.
Impact factor: 5.751
Publication type: Paper in international publication
Authors: Antonell, A, Del Campo, M, Magano, L F, Kaufmann, L, de la Iglesia, J Martinez, Gallastegui, F, Flores, R, Schweigmann, U, Fauth, C, Kotzot, D et al.
DOI: 10.1136/jmg.2009.071712

Pathogenic lysosomal depletion in Parkinson's disease.

PMID: 20844148
Journal: JOURNAL OF NEUROSCIENCE
Year: 2010
Reference: J Neurosci. 2010 Sep 15;30(37):12535-44.
Impact factor: 7.178
Publication type: Paper in international publication
Authors: Dehay, Benjamin, Bove, Jordi, Rodriguez-Muela, Natalia, Perier, Celine, Recasens, Ariadna, Boya, Patricia, Vila, Miquel et al.
DOI: 10.1523/JNEUROSCI.1920-10.2010

Pathology of the thoracic wall: congenital and acquired.

PMID: 20432004
Journal: PEDIATRIC RADIOLOGY
Year: 2010
Reference: Pediatr Radiol. 2010 Jun;40(6):859-68. doi: 10.1007/s00247-010-1604-z. Epub 2010 Apr 30.
Impact factor: 1.186
Publication type: Review in international publication
Authors: Garcia-Pena, Pilar, Barber, Ignasi et al.
DOI: 10.1007/s00247-010-1604-z

[Pathophysiology of CADASIL disease]

PMID: 20036399
Journal: MEDICINA CLINICA
Year: 2010
Reference: Med Clin (Barc). 2010 Jul 10;135(5):222-30. Epub 2009 Dec 29.
Impact factor: 1.231
Publication type: Review in national publication
Authors: Del Rio Espinola, Alberto, Sole, Esther, Montaner, Joan et al.
DOI: 10.1016/j.medcli.2009.10.034

Patients with spina bifida and bladder cancer. Our experience

PMID: NOPMID038
Journal: Cerebrospinal Fluid Research
Year: 2010
Reference: Patients with spina bifida and bladder cancer. Our experience. Cerebrospinal Fluid Res. 2010; 7(s1):s54
Impact factor: 0
Publication type: Paper in international publication
Authors: Pages Bolibar, Esther, Montesinos Magraner, Lluisa, Melendez Plumed, Mar, Rodriguez Gonzalez, Susana, Cuxart Fina, Maria Amparo et al.
DOI: 10.1186/1743-8454-7-S1-S54

Pattern of Response of National Institutes of Health Stroke Scale Components to Early Recanalization in the CLOTBUST Trial.

PMID: 20133918
Journal: STROKE
Year: 2010
Reference: Stroke. 2010 Mar;41(3):466-70. Epub 2010 Feb 4.
Impact factor: 7.041
Publication type: Paper in international publication
Authors: , , , , , , , et al.
DOI: 10.1161/STROKEAHA.109.567263

Pharmacogenomic and Pharmacoproteomic Studies of Cetuximab in Metastatic Colorectal Cancer: Biomarker Analysis of a Phase I Dose-Escalation Study.

PMID: 20100964
Journal: JOURNAL OF CLINICAL ONCOLOGY
Year: 2010
Reference: J Clin Oncol. 2010 Mar 1;28(7):1181-9. Epub 2010 Jan 25.
Impact factor: 17.793
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1200/JCO.2009.22.6043

Phase I safety, pharmacokinetics, and inhibition of SRC activity study of saracatinib in patients with solid tumors.

PMID: 20805299
Journal: CLINICAL CANCER RESEARCH
Year: 2010
Reference: Clin Cancer Res. 2010 Oct 1;16(19):4876-83. Epub 2010 Aug 30.
Impact factor: 6.747
Publication type: Paper in international publication
Authors: Baselga, Jose, Cervantes, Andres, Martinelli, Erika, Chirivella, Isabel, Hoekman, Klaas, Hurwitz, Herbert I, Jodrell, Duncan I, Hamberg, Paul, Casado, Esther, Elvin, Paul et al.
DOI: 10.1158/1078-0432.CCR-10-0748

Phase I study of the selective Aurora A kinase inhibitor MLN8054 in patients with advanced solid tumors: safety, pharmacokinetics, and pharmacodynamics.

PMID: 20724522
Journal: MOLECULAR CANCER THERAPEUTICS
Year: 2010
Reference: Mol Cancer Ther. 2010 Oct;9(10):2844-52. Epub 2010 Aug 19.
Impact factor: 4.953
Publication type: Paper in international publication
Authors: Eton, Omar, Fingert, Howard, Tabernero, Josep, Liu, Hua, Bowman, Douglas, Chakravarty, Arijit, Shinde, Vaishali, Cervantes, Andres, Elez, Elena, Rodriguez-Braun, Edith et al.
DOI: 10.1158/1535-7163.MCT-10-0299

Phase II Proof-of-Concept Study of Pazopanib Monotherapy in Treatment-Naive Patients With Stage I/II Resectable Non-Small-Cell Lung Cancer.

PMID: 20516450
Journal: JOURNAL OF CLINICAL ONCOLOGY
Year: 2010
Reference: J Clin Oncol. 2010 Jul 1;28(19):3131-7. Epub 2010 Jun 1.
Impact factor: 17.793
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1200/JCO.2009.23.9749

Phase II study of oral fingolimod (FTY720) in multiple sclerosis: 3-year results.

PMID: 20028707
Journal: MULTIPLE SCLEROSIS
Year: 2010
Reference: Mult Scler. 2010 Feb;16(2):197-207. Epub 2009 Dec 22.
Impact factor: 3.279
Publication type: Paper in international publication
Authors: Kappos, L, Comi, G, O'Connor, P, Montalban, X, Antel, J, Radue, E-W, Karlsson, G, Pohlmann, H, Aradhye, S, Kappos, L et al.
DOI: 10.1177/1352458509357065

Phase II study of the halichondrin B analog eribulin mesylate in patients with locally advanced or metastatic breast cancer previously treated with an anthracycline, a taxane, and capecitabine.

PMID: 20679609
Journal: JOURNAL OF CLINICAL ONCOLOGY
Year: 2010
Reference: J Clin Oncol. 2010 Sep 1;28(25):3922-8. Epub 2010 Aug 2.
Impact factor: 17.793
Publication type: Paper in international publication
Authors: Cortes, Javier, Vahdat, Linda, Blum, Joanne L, Twelves, Chris, Campone, Mario, Roche, Henri, Bachelot, Thomas, Awada, Ahmad, Paridaens, Robert, Goncalves, Anthony et al.
DOI: 10.1200/JCO.2009.25.8467

Phase II study of vinorelbine and estramustine in combination with conformational radiotherapy for patients with high-risk prostate cancer.

PMID: 19577864
Journal: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Year: 2010
Reference: Int J Radiat Oncol Biol Phys. 2010 Mar 15;76(4):1085-91. doi: 10.1016/j.ijrobp.2009.03.024. Epub 2009 Jul 4.
Impact factor: 4.592
Publication type: Paper in international publication
Authors: Carles, Joan, Nogue, Miguel, Sole, Josep M, Foro, Palmira, Domenech, Montserrat, Suarez, Marta, Gallardo, Enrique, Garcia, Dario, Ferrer, Ferran, Gelabert-Mas, Antoni et al.
DOI: 10.1016/j.ijrobp.2009.03.024

Phase II Trial of Pertuzumab and Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer That Progressed During Prior Trastuzumab Therapy.

PMID: 20124182
Journal: JOURNAL OF CLINICAL ONCOLOGY
Year: 2010
Reference: J Clin Oncol. 2010 Mar 1;28(7):1138-44. Epub 2010 Feb 1.
Impact factor: 17.793
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1200/JCO.2009.24.2024

Phase IIB/III trial of tenecteplase in acute ischemic stroke: results of a prematurely terminated randomized clinical trial.

PMID: 20185783
Journal: STROKE
Year: 2010
Reference: Stroke. 2010 Apr;41(4):707-11. Epub 2010 Feb 25.
Impact factor: 7.041
Publication type: Paper in international publication
Authors: Buda, M, Levine, Steven R, Johnston, Karen C, Buchsbaum, Richard, Levy, Gilberto, Levin, Bruce, Lyden, P, Hemmen, T, Meyer, B, Chacon, M et al.
DOI: 10.1161/STROKEAHA.109.572040

Phase III Study of Bevacizumab Plus Docetaxel Compared With Placebo Plus Docetaxel for the First-Line Treatment of Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer.

PMID: 20498403
Journal: JOURNAL OF CLINICAL ONCOLOGY
Year: 2010
Reference: J Clin Oncol. 2010 Jul 10;28(20):3239-47. Epub 2010 May 24.
Impact factor: 17.793
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1200/JCO.2008.21.6457

Phase III Trials of Eribulin Mesylate (E7389) in Extensively Pretreated Patients With Locally Recurrent or Metastatic Breast Cancer.

PMID: 20299316
Journal: Clinical Breast Cancer
Year: 2010
Reference: Clin Breast Cancer. 2010 Apr;10(2):160-3.
Impact factor: 2.065
Publication type: Paper in international publication
Authors: , , , , , et al.
DOI: 10.3816/CBC.2010.n.023

Phosphatidyl-inositol-3-kinase alpha catalytic subunit mutation and response to neoadjuvant endocrine therapy for estrogen receptor positive breast cancer.

PMID: 19844788
Journal: BREAST CANCER RESEARCH AND TREATMENT
Year: 2010
Reference: Breast Cancer Res Treat. 2010 Jan;119(2):379-90.
Impact factor: 4.696
Publication type: Paper in international publication
Authors: Bandaru, Raj, Liu, WeiHua, Gardner, Humphrey, Semiglazov, Vladimir, Watson, Mark, Hunt, Kelly, Olson, John, Baselga, Jose, Steinseifer, Jutta, Evans, Dean B et al.
DOI: 10.1007/s10549-009-0575-y