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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Treatment of refractory poor aPL-related obstetric outcomes with TNF-alpha blockers: Maternal-fetal outcomes in a series of 18 cases.

PMID: 30824278
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2019
Reference: Semin Arthritis Rheum. 2019 Oct;49(2):314-318. doi: 10.1016/j.semarthrit.2019.02.006. Epub 2019 Feb 11.
Impact factor: 5.072
Publication type: Paper in international publication
Authors: Alijotas-Reig, Jaume, Esteve-Valverde, Enrique, Llurba, Elisa, Gris, Josep M feminine et al.
DOI: 10.1016/j.semarthrit.2019.02.006

Treatment of refractory poor aPL-related obstetric outcomes with TNF-alpha blockers: Maternal-fetal outcomes in a series of 18 cases.

PMID: 30824278
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2019
Reference: Semin Arthritis Rheum. 2019 Oct;49(2):314-318. doi: 10.1016/j.semarthrit.2019.02.006. Epub 2019 Feb 11.
Impact factor:
Publication type: Paper in international publication
Authors: Alijotas-Reig, Jaume; Esteve-Valverde, Enrique; Gris, Josep M feminine; Llurba, Elisa et al.
DOI: 10.1016/j.semarthrit.2019.02.006

Treatment outcome in dually HIV-1 and HIV-2 coinfected patients living in Spain.

PMID: 31373918
Journal: AIDS
Year: 2019
Reference: AIDS. 2019 Nov 15;33(14):2167-2172. doi: 10.1097/QAD.0000000000002338.
Impact factor: 4.499
Publication type: Paper in international publication
Authors: Rios-Villegas, Maria Jose, Requena, Silvia, Caballero, Estrella, Lozano, Ana Belen, Cabezas, Teresa, Macia, Maria Dolores, Nieto, Maria Del Carmen, Soriano, Vicente, de Mendoza, Carmen, Rojo, Silvia et al.
DOI: 10.1097/QAD.0000000000002338

Treatment outcome in dually HIV-1 and HIV-2 coinfected patients living in Spain.

PMID: 31373918
Journal: AIDS
Year: 2019
Reference: AIDS. 2019 Nov 15;33(14):2167-2172. doi: 10.1097/QAD.0000000000002338.
Impact factor:
Publication type: Paper in international publication
Authors: Benito, Rafael; Caballero, Estrella; Cabezas, Teresa; de Mendoza, Carmen; Lozano, Ana Belen; Macia, Maria Dolores; Nieto, Maria Del Carmen; Requena, Silvia; Rios-Villegas, Maria Jose; Rojo, Silvia et al.
DOI: 10.1097/QAD.0000000000002338

Treatment Outcomes and Adverse Events from a Standardized Multidrug-Resistant Tuberculosis Regimen in a Rural Setting in Angola.

PMID: 31333153
Journal: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
Year: 2019
Reference: Am J Trop Med Hyg. 2019 Sep;101(3):502-509. doi: 10.4269/ajtmh.19-0175.
Impact factor: 2.315
Publication type: Paper in international publication
Authors: Bocanegra, Cristina, Olivas, Eva Gil, Eugenio, Arlete Nindia, Zacarias, Adriano, Katimba, Domingos, Gabriel, Estevao, Mendioroz, Jacobo, Lopez Garcia, Maria Teresa, Sune, Tomas Pumarola, Tortola Fernandez, Maria Teresa et al.
DOI: 10.4269/ajtmh.19-0175

Treatment Outcomes and Adverse Events from a Standardized Multidrug-Resistant Tuberculosis Regimen in a Rural Setting in Angola.

PMID: 31333153
Journal: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
Year: 2019
Reference: Am J Trop Med Hyg. 2019 Sep;101(3):502-509. doi: 10.4269/ajtmh.19-0175.
Impact factor:
Publication type: Paper in international publication
Authors: Aznar, Maria Luisa; Bocanegra, Cristina; Eugenio, Arlete Nindia; Gabriel, Estevao; Igual, Elena Sulleiro; Katimba, Domingos; Lopez Garcia, Maria Teresa; Mendioroz, Jacobo; Moreno, Maria Milagros; Olivas, Eva Gil et al.
DOI: 10.4269/ajtmh.19-0175

Treatment Patterns and Use of Resources in Patients With Tuberous Sclerosis Complex: Insights From the TOSCA Registry.

PMID: 31708865
Journal: Frontiers in Neurology
Year: 2019
Reference: Front Neurol. 2019 Oct 25;10:1144. doi: 10.3389/fneur.2019.01144. eCollection 2019.
Impact factor: 2.635
Publication type: Paper in international publication
Authors: Takahashi, Yukitoshi, Touraine, Renaud, Youroukos, Sotiris, Zonnenberg, Bernard, Kingswood, John C, Jansen, Anna C, Shah, Seema, Sauter, Matthias, Sander, Valentin, Qin, Jiong et al.
DOI: 10.3389/fneur.2019.01144

Treatment Patterns and Use of Resources in Patients With Tuberous Sclerosis Complex: Insights From the TOSCA Registry.

PMID: 31708865
Journal: Frontiers in Neurology
Year: 2019
Reference: Front Neurol. 2019 Oct 25;10:1144. doi: 10.3389/fneur.2019.01144. eCollection 2019.
Impact factor:
Publication type: Paper in international publication
Authors: Beaure d'Augeres, Guillaume; Belousova, Elena; Benedik, Mirjana P; Carter, Tom; Cottin, Vincent; Curatolo, Paolo; D'Amato, Lisa; Dahlin, Maria; de Vries, Petrus J; Ferreira, Jose C et al.
DOI: 10.3389/fneur.2019.01144

Treatment with inhaled alpha1-antitrypsin: a square peg in a round hole?

PMID: 31754075
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2019
Reference: Eur Respir J. 2019 Nov 21;54(5). pii: 54/5/1901894. doi: 10.1183/13993003.01894-2019. Print 2019 Nov.
Impact factor: 11.807
Publication type: Editorail in international publication
Authors: Barrecheguren, Miriam, Miravitlles, Marc et al.
DOI: 10.1183/13993003.01894-2019

Treatment with inhaled alpha1-antitrypsin: a square peg in a round hole?

PMID: 31754075
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2019
Reference: Eur Respir J. 2019 Nov 21;54(5). pii: 54/5/1901894. doi: 10.1183/13993003.01894-2019. Print 2019 Nov.
Impact factor:
Publication type: Editorail in international publication
Authors: Barrecheguren, Miriam; Miravitlles, Marc et al.
DOI: 10.1183/13993003.01894-2019

Trebananib or placebo plus carboplatin and paclitaxel as first-line treatment for advanced ovarian cancer (TRINOVA-3/ENGOT-ov2/GOG-3001): a randomised, double-blind, phase 3 trial.

PMID: 31076365
Journal: LANCET ONCOLOGY
Year: 2019
Reference: Lancet Oncol. 2019 Jun;20(6):862-876. doi: 10.1016/S1470-2045(19)30178-0. Epub 2019 May 7.
Impact factor: 35.386
Publication type: Paper in international publication
Authors: Meier, Werner, Vergote, Ignace, Scambia, Giovanni, O'Malley, David M, Van Calster, Ben, Park, Sang-Yoon, Del Campo, Josep M, Colombo, Nicoletta, Lisyanskaya, Alla, Benzaquen, Ana Oaknin et al.
DOI: 10.1016/S1470-2045(19)30178-0

Trebananib or placebo plus carboplatin and paclitaxel as first-line treatment for advanced ovarian cancer (TRINOVA-3/ENGOT-ov2/GOG-3001): a randomised, double-blind, phase 3 trial.

PMID: 31076365
Journal: LANCET ONCOLOGY
Year: 2019
Reference: Lancet Oncol. 2019 Jun;20(6):862-876. doi: 10.1016/S1470-2045(19)30178-0. Epub 2019 May 7.
Impact factor:
Publication type: Paper in international publication
Authors: Alabiso, Oscar; Alavez, Alejandro Molina; Alia, Eva Guerra; Anderson, Daniel; Anderson, Jeanne; Andrews, Stephen; Aoki, Daisuke; Arango, Hector; Aravantinos, Gerasimos; Arija, Jose Angel Arranz et al.
DOI: 10.1016/S1470-2045(19)30178-0

Trends and Bibliometric Impact of Research Grants of the Spanish Society of Cardiology/Spanish Heart Foundation (2007-2012).

PMID: 30905664
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Dec;72(12):1012-1019. doi: 10.1016/j.rec.2018.08.029. Epub 2019 Mar 22.
Impact factor: 5.078
Publication type: Paper in national publication
Authors: Rodriguez-Padial, Luis, Fernandez Lozano, Ignacio, Hidalgo Urbano, Rafael, Silva Melchor, Lorenzo, Evangelista Massip, Arturo, Anguita Sanchez, Manuel, Iniguez Romo, Andres et al.
DOI: 10.1016/j.rec.2018.08.029

Trends and Bibliometric Impact of Research Grants of the Spanish Society of Cardiology/Spanish Heart Foundation (2007-2012).

PMID: 30905664
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Dec;72(12):1012-1019. doi: 10.1016/j.rec.2018.08.029. Epub 2019 Mar 22.
Impact factor:
Publication type: Paper in national publication
Authors: Anguita Sanchez, Manuel; Evangelista Massip, Arturo; Fernandez Lozano, Ignacio; Hidalgo Urbano, Rafael; Iniguez Romo, Andres; Rodriguez-Padial, Luis; Silva Melchor, Lorenzo et al.
DOI: 10.1016/j.rec.2018.08.029

Trends in endpoint selection and result interpretation in advanced non-small cell lung cancer clinical trials published between 2000 and 2012: A retrospective cohort study.

PMID: 30868737
Journal: Thoracic Cancer
Year: 2019
Reference: Thorac Cancer. 2019 Apr;10(4):904-908. doi: 10.1111/1759-7714.13024. Epub 2019 Mar 13.
Impact factor: 2.524
Publication type: Paper in international publication
Authors: Calleja-Hernandez, Miguel Angel, Balbino, Jaime Espin, Cabeza-Barrera, Jose, Exposito-Hernandez, Jose, Fernandez-Lopez, Cristina et al.
DOI: 10.1111/1759-7714.13024

Trends in endpoint selection and result interpretation in advanced non-small cell lung cancer clinical trials published between 2000 and 2012: A retrospective cohort study.

PMID: 30868737
Journal: Thoracic Cancer
Year: 2019
Reference: Thorac Cancer. 2019 Apr;10(4):904-908. doi: 10.1111/1759-7714.13024. Epub 2019 Mar 13.
Impact factor:
Publication type: Paper in international publication
Authors: Balbino, Jaime Espin; Cabeza-Barrera, Jose; Calleja-Hernandez, Miguel Angel; Exposito-Hernandez, Jose; Fernandez-Lopez, Cristina et al.
DOI: 10.1111/1759-7714.13024

Trends in healthcare resource use and expenditure before and after ischaemic stroke. A population-based study.

PMID: 30902459
Journal: Neurologia (Barcelona, Spain)
Year: 2019
Reference: Neurologia (Engl Ed). 2019 Mar 19. pii: S0213-4853(19)30005-2. doi: 10.1016/j.nrl.2018.11.002.
Impact factor: 0
Publication type: Paper in national publication
Authors: Ribera, A, Vela, E, Garcia-Altes, A, Cleries, M, Abilleira, S et al.
DOI: 10.1016/j.nrl.2018.11.002

Trends in healthcare resource use and expenditure before and after ischaemic stroke. A population-based study.

PMID: 30902459
Journal: Neurologia (Barcelona, Spain)
Year: 2019
Reference: Neurologia (Engl Ed). 2019 Mar 19. pii: S0213-4853(19)30005-2. doi: 10.1016/j.nrl.2018.11.002.
Impact factor:
Publication type: Paper in national publication
Authors: Abilleira, S; Cleries, M; Garcia-Altes, A; Ribera, A; Vela, E et al.
DOI: 10.1016/j.nrl.2018.11.002

Trial protocol for the validation of the 'Toronto Aortic Stenosis Quality of Life (TASQ) Questionnaire' in patients undergoing surgical aortic valve replacement (SAVR) or transfemoral (TF) transcatheter aortic valve implantation (TAVI): the TASQ registry.

PMID: 31218003
Journal: Open heart
Year: 2019
Reference: Open Heart. 2019 May 21;6(1):e001008. doi: 10.1136/openhrt-2019-001008. eCollection 2019.
Impact factor: 0
Publication type: Paper in international publication
Authors: Frank, Derk, Kennon, Simon, Bonaros, Nikolaos, Romano, Mauro, Lefevre, Thierry, Di Mario, Carlo, Stefano, Pierluigi, Ribichini, Flavio Luciano, Himbert, Dominique, Urena-Alcazar, Marina et al.
DOI: 10.1136/openhrt-2019-001008

Trial protocol for the validation of the 'Toronto Aortic Stenosis Quality of Life (TASQ) Questionnaire' in patients undergoing surgical aortic valve replacement (SAVR) or transfemoral (TF) transcatheter aortic valve implantation (TAVI): the TASQ registry.

PMID: 31218003
Journal: Open heart
Year: 2019
Reference: Open Heart. 2019 May 21;6(1):e001008. doi: 10.1136/openhrt-2019-001008. eCollection 2019.
Impact factor:
Publication type: Paper in international publication
Authors: Bonaros, Nikolaos; Bramlage, Peter; Cuenca Castillo, Jose Joaquin; Di Mario, Carlo; Frank, Derk; Garcia, Bruno; Himbert, Dominique; Kennon, Simon; Kurucova, Jana; Lefevre, Thierry et al.
DOI: 10.1136/openhrt-2019-001008

Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages.

PMID: 31028084
Journal: EMBO JOURNAL
Year: 2019
Reference: EMBO J. 2019 Jun 3;38(11). pii: embj.2018100299. doi: 10.15252/embj.2018100299. Epub 2019 Apr 26.
Impact factor: 11.227
Publication type: Paper in international publication
Authors: Guo, Manman, Hartlova, Anetta, Gierlinski, Marek, Prescott, Alan, Castellvi, Josep, Losa, Javier Hernandez, Petersen, Sine K, Wenzel, Ulf A, Dill, Brian D, Emmerich, Christoph H et al.
DOI: 10.15252/embj.2018100299

Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages.

PMID: 31028084
Journal: EMBO JOURNAL
Year: 2019
Reference: EMBO J. 2019 Jun 3;38(11). pii: embj.2018100299. doi: 10.15252/embj.2018100299. Epub 2019 Apr 26.
Impact factor:
Publication type: Paper in international publication
Authors: Castellvi, Josep; Dill, Brian D; Emmerich, Christoph H; Gierlinski, Marek; Guo, Manman; Hartlova, Anetta; Losa, Javier Hernandez; Petersen, Sine K; Prescott, Alan; Ramon Y Cajal, Santiago et al.
DOI: 10.15252/embj.2018100299

Triple blockade of EGFR, MEK and PD-L1 has antitumor activity in colorectal cancer models with constitutive activation of MAPK signaling and PD-L1 overexpression.

PMID: 31842958
Journal: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Year: 2019
Reference: J Exp Clin Cancer Res. 2019 Dec 16;38(1):492. doi: 10.1186/s13046-019-1497-0.
Impact factor: 5.646
Publication type: Paper in international publication
Authors: Troiani, T, Morgillo, F, Napolitano, S, Matrone, N, Muddassir, A L, Martini, G, Sorokin, A, De Falco, V, Giunta, E F, Ciardiello, D et al.
DOI: 10.1186/s13046-019-1497-0

Triple blockade of EGFR, MEK and PD-L1 has antitumor activity in colorectal cancer models with constitutive activation of MAPK signaling and PD-L1 overexpression.

PMID: 31842958
Journal: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Year: 2019
Reference: J Exp Clin Cancer Res. 2019 Dec 16;38(1):492. doi: 10.1186/s13046-019-1497-0.
Impact factor:
Publication type: Paper in international publication
Authors: Belli, V; Ciardiello, D; Ciardiello, F; De Falco, V; Furia, M; Giunta, E F; Kopetz, S; Martinelli, E; Martini, G; Matrone, N et al.
DOI: 10.1186/s13046-019-1497-0