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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT).

PMID: 30137196
Journal: ANNALS OF ONCOLOGY
Year: 2018
Reference: Ann Oncol. 2018 Sep 1;29(9):1895-1902. doi: 10.1093/annonc/mdy263.
Impact factor:
Publication type: Paper in international publication
Authors: Andre, F; Bedard, P L; Chakravarty, D; Dienstmann, R; Douillard, J-Y; Gonzalez-Perez, A; Jezdic, S; Lopez-Bigas, N; Mateo, J; Ng, C K Y et al.
DOI: 10.1093/annonc/mdy263

A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder.

PMID: 29325848
Journal: BIOLOGICAL PSYCHIATRY
Year: 2018
Reference: Biol Psychiatry. 2018 Jun 15;83(12):1044-1053. doi: 10.1016/j.biopsych.2017.11.026. Epub 2017 Dec 2.
Impact factor: 11.982
Publication type: Paper in international publication
Authors: Hervas, Amaia, Mors, Ole, Nordentoft, Merete, Hougaard, David M, Bybjerg-Grauholm, Jonas, Wray, Naomi R, Franke, Barbara, Faraone, Stephen V, O'Donovan, Michael C, Thapar, Anita et al.
DOI: 10.1016/j.biopsych.2017.11.026

A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder.

PMID: 29325848
Journal: BIOLOGICAL PSYCHIATRY
Year: 2018
Reference: Biol Psychiatry. 2018 Jun 15;83(12):1044-1053. doi: 10.1016/j.biopsych.2017.11.026. Epub 2017 Dec 2.
Impact factor:
Publication type: Paper in international publication
Authors: Agee, Michelle; Agerbo, Esben; Albayrak, Ozgur; Alipanahi, Babak; Als, Thomas Damm; Anney, Richard J L; Arranz, Maria Jesus; Asherson, Philip; Auton, Adam; Baekved-Hansen, Marie et al.
DOI: 10.1016/j.biopsych.2017.11.026

A homozygous loss-of-function mutation in PDE2A associated to early-onset hereditary chorea.

PMID: 29392776
Journal: MOVEMENT DISORDERS
Year: 2018
Reference: Mov Disord. 2018 Mar;33(3):482-488. doi: 10.1002/mds.27286. Epub 2018 Feb 2.
Impact factor: 8.324
Publication type: Paper in international publication
Authors: Bettencourt, Conceicao, Mencacci, Niccolo E, Klein, Christine, Kelly, Michy P, Davies, Ceri H, Kimura, Haruhide, Macaya, Alfons, Houlden, Henry, Vandrovcova, Jana, Efthymiou, Stephanie et al.
DOI: 10.1002/mds.27286

A homozygous loss-of-function mutation in PDE2A associated to early-onset hereditary chorea.

PMID: 29392776
Journal: MOVEMENT DISORDERS
Year: 2018
Reference: Mov Disord. 2018 Mar;33(3):482-488. doi: 10.1002/mds.27286. Epub 2018 Feb 2.
Impact factor:
Publication type: Paper in international publication
Authors: Bettencourt, Conceicao; Davies, Ceri H; Efthymiou, Stephanie; Houlden, Henry; Kelly, Michy P; Kimura, Haruhide; Klein, Christine; Macaya, Alfons; Manole, Andreea; Mencacci, Niccolo E et al.
DOI: 10.1002/mds.27286

A kidney-disease gene panel allows a comprehensive genetic diagnosis of cystic and glomerular inherited kidney diseases.

PMID: 29801666
Journal: KIDNEY INTERNATIONAL
Year: 2018
Reference: Kidney Int. 2018 Aug;94(2):363-371. doi: 10.1016/j.kint.2018.02.027. Epub 2018 May 22.
Impact factor: 8.429
Publication type: Paper in international publication
Authors: Bullich, Gemma, Domingo-Gallego, Andrea, Vargas, Ivan, Ruiz, Patricia, Lorente-Grandoso, Laura, Furlano, Monica, Fraga, Gloria, Madrid, Alvaro, Ariceta, Gema, Borregan, Mar et al.
DOI: 10.1016/j.kint.2018.02.027

A kidney-disease gene panel allows a comprehensive genetic diagnosis of cystic and glomerular inherited kidney diseases.

PMID: 29801666
Journal: KIDNEY INTERNATIONAL
Year: 2018
Reference: Kidney Int. 2018 Aug;94(2):363-371. doi: 10.1016/j.kint.2018.02.027. Epub 2018 May 22.
Impact factor:
Publication type: Paper in international publication
Authors: Ariceta, Gema; Ars, Elisabet; Ballarin, Jose; Ballesta-Martinez, Maria Juliana; Borregan, Mar; Bullich, Gemma; Domingo-Gallego, Andrea; Fraga, Gloria; Furlano, Monica; Llano-Rivas, Isabel et al.
DOI: 10.1016/j.kint.2018.02.027

A Kinematic Sensor and Algorithm to Detect Motor Fluctuations in Parkinson Disease: Validation Study Under Real Conditions of Use.

PMID: 29695377
Journal: JMIR rehabilitation and assistive technologies
Year: 2018
Reference: JMIR Rehabil Assist Technol. 2018 Apr 25;5(1):e8. doi: 10.2196/rehab.8335.
Impact factor: 0
Publication type: Paper in international publication
Authors: Rodriguez-Molinero, Alejandro, Sama, Albert, de Mingo, Eva, Rodriguez-Martin, Daniel, Hernandez-Vara, Jorge, Bayes, Angels, Moral, Alfons, Alvarez, Ramiro, Perez-Martinez, David A, Catala, Andreu et al.
DOI: 10.2196/rehab.8335

A Kinematic Sensor and Algorithm to Detect Motor Fluctuations in Parkinson Disease: Validation Study Under Real Conditions of Use.

PMID: 29695377
Journal: JMIR rehabilitation and assistive technologies
Year: 2018
Reference: JMIR Rehabil Assist Technol. 2018 Apr 25;5(1):e8. doi: 10.2196/rehab.8335.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez, Ramiro; Bayes, Angels; Catala, Andreu; de Mingo, Eva; Hernandez-Vara, Jorge; Moral, Alfons; Perez-Lopez, Carlos; Perez-Martinez, David A; Rodriguez-Martin, Daniel; Rodriguez-Molinero, Alejandro et al.
DOI: 10.2196/rehab.8335

A mouse model of disseminated mantle cell lymphoma highlights a lack of activity of estrogen receptor beta agonists toward tumor burden.

PMID: 29164964
Journal: LEUKEMIA & LYMPHOMA
Year: 2018
Reference: Leuk Lymphoma. 2018 Jul;59(7):1726-1729. doi: 10.1080/10428194.2017.1399313. Epub 2017 Nov 22.
Impact factor: 2.644
Publication type: Letter whit IF
Authors: Body, Simon, Esteve-Arenys, Anna, Recasens-Zorzo, Clara, Troussard, Xavier, Roue, Gael, Sola, Brigitte et al.
DOI: 10.1080/10428194.2017.1399313

A mouse model of disseminated mantle cell lymphoma highlights a lack of activity of estrogen receptor beta agonists toward tumor burden.

PMID: 29164964
Journal: LEUKEMIA & LYMPHOMA
Year: 2018
Reference: Leuk Lymphoma. 2018 Jul;59(7):1726-1729. doi: 10.1080/10428194.2017.1399313. Epub 2017 Nov 22.
Impact factor:
Publication type: Letter whit IF
Authors: Body, Simon; Esteve-Arenys, Anna; Recasens-Zorzo, Clara; Roue, Gael; Sola, Brigitte; Troussard, Xavier et al.
DOI: 10.1080/10428194.2017.1399313

A new approach to obtain pure and active proteins from Lactococcus lactis protein aggregates.

PMID: 30224788
Journal: Scientific Reports
Year: 2018
Reference: Sci Rep. 2018 Sep 17;8(1):13917. doi: 10.1038/s41598-018-32213-8.
Impact factor: 4.122
Publication type: Paper in international publication
Authors: Gifre-Renom, L, Cano-Garrido, O, Fabregas, F, Roca-Pinilla, R, Seras-Franzoso, J, Ferrer-Miralles, N, Villaverde, A, Bach, A, Devant, M, Aris, A et al.
DOI: 10.1038/s41598-018-32213-8

A new approach to obtain pure and active proteins from Lactococcus lactis protein aggregates.

PMID: 30224788
Journal: Scientific Reports
Year: 2018
Reference: Sci Rep. 2018 Sep 17;8(1):13917. doi: 10.1038/s41598-018-32213-8.
Impact factor:
Publication type: Paper in international publication
Authors: Aris, A; Bach, A; Cano-Garrido, O; Devant, M; Fabregas, F; Ferrer-Miralles, N; Garcia-Fruitos, E; Gifre-Renom, L; Roca-Pinilla, R; Seras-Franzoso, J et al.
DOI: 10.1038/s41598-018-32213-8

A novel EPM2A mutation yields a slow progression form of Lafora disease.

PMID: 30041081
Journal: EPILEPSY RESEARCH
Year: 2018
Reference: Epilepsy Res. 2018 Sep;145:169-177. doi: 10.1016/j.eplepsyres.2018.07.003. Epub 2018 Jul 21.
Impact factor: 2.491
Publication type: Paper in international publication
Authors: Garcia-Gimeno, Maria Adelaida, Rodilla-Ramirez, Pilar Natalia, Viana, Rosa, Salas-Puig, Xavier, Brewer, M Kathryn, Gentry, Matthew S, Sanz, Pascual et al.
DOI: 10.1016/j.eplepsyres.2018.07.003

A novel EPM2A mutation yields a slow progression form of Lafora disease.

PMID: 30041081
Journal: EPILEPSY RESEARCH
Year: 2018
Reference: Epilepsy Res. 2018 Sep;145:169-177. doi: 10.1016/j.eplepsyres.2018.07.003. Epub 2018 Jul 21.
Impact factor:
Publication type: Paper in international publication
Authors: Brewer, M Kathryn; Garcia-Gimeno, Maria Adelaida; Gentry, Matthew S; Rodilla-Ramirez, Pilar Natalia; Salas-Puig, Xavier; Sanz, Pascual; Viana, Rosa et al.
DOI: 10.1016/j.eplepsyres.2018.07.003

A Novel Heterozygous Intronic Mutation in the FBN1 Gene Contributes to FBN1 RNA Missplicing Events in the Marfan Syndrome.

PMID: 30003093
Journal: Biomed Research International
Year: 2018
Reference: Biomed Res Int. 2018 May 29;2018:3536495. doi: 10.1155/2018/3536495. eCollection 2018.
Impact factor: 2.583
Publication type: Paper in international publication
Authors: Torrado, Mario, Maneiro, Emilia, Trujillo-Quintero, Juan Pablo, Evangelista, Arturo, Mikhailov, Alexander T, Monserrat, Lorenzo et al.
DOI: 10.1155/2018/3536495

A Novel Heterozygous Intronic Mutation in the FBN1 Gene Contributes to FBN1 RNA Missplicing Events in the Marfan Syndrome.

PMID: 30003093
Journal: Biomed Research International
Year: 2018
Reference: Biomed Res Int. 2018 May 29;2018:3536495. doi: 10.1155/2018/3536495. eCollection 2018.
Impact factor:
Publication type: Paper in international publication
Authors: Evangelista, Arturo; Maneiro, Emilia; Mikhailov, Alexander T; Monserrat, Lorenzo; Torrado, Mario; Trujillo-Quintero, Juan Pablo et al.
DOI: 10.1155/2018/3536495

A novel marker for identifying and studying the membranes, barriers, and compartments surrounding peripheral nerves microscopically.

PMID: 30113091
Journal: CLINICAL ANATOMY
Year: 2018
Reference: Clin Anat. 2018 Oct;31(7):1050-1057. doi: 10.1002/ca.23253. Epub 2018 Oct 26.
Impact factor: 1.908
Publication type: Paper in international publication
Authors: Reina, Miguel A, Boezaart, Andre P, Sala-Blanch, Xavier, Monzo, Enrique, Shane Tubbs, R, Server, Anna, Bigeleisen, Paul et al.
DOI: 10.1002/ca.23253

A novel marker for identifying and studying the membranes, barriers, and compartments surrounding peripheral nerves microscopically.

PMID: 30113091
Journal: CLINICAL ANATOMY
Year: 2018
Reference: Clin Anat. 2018 Oct;31(7):1050-1057. doi: 10.1002/ca.23253. Epub 2018 Oct 26.
Impact factor:
Publication type: Paper in international publication
Authors: Bigeleisen, Paul; Boezaart, Andre P; Monzo, Enrique; Reina, Miguel A; Sala-Blanch, Xavier; Server, Anna; Shane Tubbs, R et al.
DOI: 10.1002/ca.23253

A pan-cancer landscape of interactions between solid tumors and infiltrating immune cell populations.

PMID: 29666300
Journal: CLINICAL CANCER RESEARCH
Year: 2018
Reference: Clin Cancer Res. 2018 Aug 1;24(15):3717-3728. doi: 10.1158/1078-0432.CCR-17-3509. Epub 2018 Apr 17.
Impact factor: 10.199
Publication type: Paper in international publication
Authors: Tamborero, David, Rubio-Perez, Carlota, Muinos, Ferran, Sabarinathan, Radhakrishnan, Piulats, Josep Maria, Muntasell, Aura, Dienstmann, Rodrigo, Lopez-Bigas, Nuria, Gonzalez-Perez, Abel et al.
DOI: 10.1158/1078-0432.CCR-17-3509

A pan-cancer landscape of interactions between solid tumors and infiltrating immune cell populations.

PMID: 29666300
Journal: CLINICAL CANCER RESEARCH
Year: 2018
Reference: Clin Cancer Res. 2018 Aug 1;24(15):3717-3728. doi: 10.1158/1078-0432.CCR-17-3509. Epub 2018 Apr 17.
Impact factor:
Publication type: Paper in international publication
Authors: Dienstmann, Rodrigo; Gonzalez-Perez, Abel; Lopez-Bigas, Nuria; Muinos, Ferran; Muntasell, Aura; Piulats, Josep Maria; Rubio-Perez, Carlota; Sabarinathan, Radhakrishnan; Tamborero, David et al.
DOI: 10.1158/1078-0432.CCR-17-3509

A Phase 2 multicenter study of the anti-CD19 antibody drug conjugate coltuximab ravtansine (SAR3419) in patients with relapsed or refractory diffuse large B-cell lymphoma previously treated with rituximab-based immunotherapy.

PMID: 29748443
Journal: HAEMATOLOGICA
Year: 2018
Reference: Haematologica. 2018 Aug;103(8):1351-1358. doi: 10.3324/haematol.2017.168401. Epub 2018 May 10.
Impact factor: 9.09
Publication type: Paper in international publication
Authors: Verhoef, Gregor, Dyer, Martin Js, Yehuda, Dina Ben, Patti, Caterina, Canales, Miguel, Lopez, Andres, Awan, Farrukh T, Montgomery, Paul G, Janikova, Andrea, Barbui, Anna M et al.
DOI: 10.3324/haematol.2017.168401

A Phase 2 multicenter study of the anti-CD19 antibody drug conjugate coltuximab ravtansine (SAR3419) in patients with relapsed or refractory diffuse large B-cell lymphoma previously treated with rituximab-based immunotherapy.

PMID: 29748443
Journal: HAEMATOLOGICA
Year: 2018
Reference: Haematologica. 2018 Aug;103(8):1351-1358. doi: 10.3324/haematol.2017.168401. Epub 2018 May 10.
Impact factor:
Publication type: Paper in international publication
Authors: Awan, Farrukh T; Barbui, Anna M; Canales, Miguel; Di Nicola, Massimo; Dyer, Martin Js; Gianni, Alessandro M; Guidetti, Anna; Hatteville, Laurence; Janikova, Andrea; Lopez, Andres et al.
DOI: 10.3324/haematol.2017.168401

A Phase Ib, open-label, dose-finding study of alpelisib in combination with paclitaxel in patients with advanced solid tumors.

PMID: 30167089
Journal: Oncotarget
Year: 2018
Reference: Oncotarget. 2018 Aug 3;9(60):31709-31718. doi: 10.18632/oncotarget.25854. eCollection 2018 Aug 3.
Impact factor: 0
Publication type: Clinical Trials
Authors: Han, Yu, Rodon, Jordi, Curigliano, Giuseppe, Delord, Jean-Pierre, Harb, Wael, Azaro, Analia, Sellami, Dalila, Beck, Thaddeus, Donnet, Valerie, Wilke, Celine et al.
DOI: 10.18632/oncotarget.25854