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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Effects of Polyphenols on Thermogenesis and Mitochondrial Biogenesis.

PMID: 30217101
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2018
Reference: Int J Mol Sci. 2018 Sep 13;19(9). pii: ijms19092757. doi: 10.3390/ijms19092757.
Impact factor:
Publication type: Review in international publication
Authors: A Villena, Josep; Cristina Pereira, Quelita; Gambero, Alessandra; Lima Ribeiro, Marcelo; Teixeira, Lucimara; Wood Dos Santos, Tanila et al.
DOI: 10.3390/ijms19092757

Effects of Prebiotics vs a Diet Low in Fodmaps in Patients with Functional Gut Disorder.

PMID: 29964041
Journal: GASTROENTEROLOGY
Year: 2018
Reference: Gastroenterology. 2018 Oct;155(4):1004-1007. doi: 10.1053/j.gastro.2018.06.045. Epub 2018 Jun 30.
Impact factor: 20.773
Publication type: Paper in international publication
Authors: Huaman, Jose-Walter, Mego, Marianela, Manichanh, Chaysavanh, Canellas, Nicolau, Canueto, Daniel, Segurola, Hegoi, Jansana, Marta, Malagelada, Carolina, Accarino, Anna, Vulevic, Jelena et al.
DOI: 10.1053/j.gastro.2018.06.045

Effects of Prebiotics vs a Diet Low in Fodmaps in Patients with Functional Gut Disorder.

PMID: 29964041
Journal: GASTROENTEROLOGY
Year: 2018
Reference: Gastroenterology. 2018 Oct;155(4):1004-1007. doi: 10.1053/j.gastro.2018.06.045. Epub 2018 Jun 30.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Canellas, Nicolau; Canueto, Daniel; Gibson, Glenn; Guarner, Francisco; Huaman, Jose-Walter; Jansana, Marta; Malagelada, Carolina; Manichanh, Chaysavanh et al.
DOI: 10.1053/j.gastro.2018.06.045

Effects of systematic variation in size and surface coating of silver nanoparticles on their in vitro toxicity to macrophage RAW 264.7 cells.

PMID: 29106689
Journal: TOXICOLOGICAL SCIENCES
Year: 2018
Reference: Toxicol Sci. 2018 Mar 1;162(1):79-88. doi: 10.1093/toxsci/kfx228.
Impact factor: 4.181
Publication type: Paper in international publication
Authors: Makama, Sunday, Kloet, Samantha K, Piella, Jordi, van den Berg, Hans, de Ruijter, Norbert C A, Puntes, Victor F, Rietjens, Ivonne M C M, van den Brink, Nico W et al.
DOI: 10.1093/toxsci/kfx228

Effects of systematic variation in size and surface coating of silver nanoparticles on their in vitro toxicity to macrophage RAW 264.7 cells.

PMID: 29106689
Journal: TOXICOLOGICAL SCIENCES
Year: 2018
Reference: Toxicol Sci. 2018 Mar 1;162(1):79-88. doi: 10.1093/toxsci/kfx228.
Impact factor:
Publication type: Paper in international publication
Authors: de Ruijter, Norbert C A; Kloet, Samantha K; Makama, Sunday; Piella, Jordi; Puntes, Victor F; Rietjens, Ivonne M C M; van den Berg, Hans; van den Brink, Nico W et al.
DOI: 10.1093/toxsci/kfx228

Efficacy and Safety of an Aflibercept Treat-and-Extend Regimen in Treatment-Naive Patients with Macular Oedema Secondary to Central Retinal Vein Occlusion (CRVO): A Prospective 12-Month, Single-Arm, Multicentre Trial.

PMID: 30405907
Journal: Journal of Ophthalmology
Year: 2018
Reference: J Ophthalmol. 2018 Oct 14;2018:8310350. doi: 10.1155/2018/8310350. eCollection 2018.
Impact factor: 1.68
Publication type: Paper in international publication
Authors: Manzanas, Lucia, Garcia-Arumi, Jose, Gomez-Ulla, Francisco, Amparo, Navea, Cervera, Enrique, Fonollosa, Alex, Arias, Luis, Araiz, Javier, Donate, Juan, de Figueroa, Marta Suarez et al.
DOI: 10.1155/2018/8310350

Efficacy and Safety of an Aflibercept Treat-and-Extend Regimen in Treatment-Naive Patients with Macular Oedema Secondary to Central Retinal Vein Occlusion (CRVO): A Prospective 12-Month, Single-Arm, Multicentre Trial.

PMID: 30405907
Journal: Journal of Ophthalmology
Year: 2018
Reference: J Ophthalmol. 2018 Oct 14;2018:8310350. doi: 10.1155/2018/8310350. eCollection 2018.
Impact factor:
Publication type: Paper in international publication
Authors: Amparo, Navea; Araiz, Javier; Arias, Luis; Cervera, Enrique; Crespi, Jaume; de Figueroa, Marta Suarez; Donate, Juan; Fonollosa, Alex; Gallego, Roberto; Garcia-Arumi, Jose et al.
DOI: 10.1155/2018/8310350

Efficacy and safety of fluocinolone acetonide 0.025% otic solution in patients with otic eczema: a randomized, double-blind, placebo-controlled clinical trial.

PMID: 30141364
Journal: JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
Year: 2018
Reference: J Int Med Res. 2018 Oct;46(10):4050-4060. doi: 10.1177/0300060518765333. Epub 2018 Aug 24.
Impact factor: 1.023
Publication type: Clinical Trials
Authors: Montoro, Victoria, Asensio, Carlos, Martinez, Angel, Lorente, Juan, Rodriguez, Francisco J, Montojo, Jose, Gavilanes, Javier, Sarria, Pedro, Langdon, Cristobal, Prades, Eduard et al.
DOI: 10.1177/0300060518765333

Efficacy and safety of fluocinolone acetonide 0.025% otic solution in patients with otic eczema: a randomized, double-blind, placebo-controlled clinical trial.

PMID: 30141364
Journal: JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
Year: 2018
Reference: J Int Med Res. 2018 Oct;46(10):4050-4060. doi: 10.1177/0300060518765333. Epub 2018 Aug 24.
Impact factor:
Publication type: Clinical Trials
Authors: Asensio, Carlos; Gavilanes, Javier; Langdon, Cristobal; Lorente, Juan; Martinez, Angel; Montojo, Jose; Montoro, Victoria; Prades, Eduard; Rodriguez, Francisco J; Sarria, Pedro et al.
DOI: 10.1177/0300060518765333

Efficacy and safety of native versus pegylated Escherichia coli asparaginase for treatment of adults with high-risk, Philadelphia chromosome-negative acute lymphoblastic leukemia.

PMID: 29165013
Journal: LEUKEMIA & LYMPHOMA
Year: 2018
Reference: Leuk Lymphoma. 2018 Jul;59(7):1634-1643. doi: 10.1080/10428194.2017.1397661. Epub 2017 Nov 22.
Impact factor: 2.644
Publication type: Paper in international publication
Authors: Martino, Rodrigo, Barba, Pere, Soria, Beatriz, Bermudez, Arancha, Moreno, Maria-Jose, Gonzalez-Campos, Jose, Vives, Susana, Gil, Cristina, Abella, Eugenia, Guardia, Ramon et al.
DOI: 10.1080/10428194.2017.1397661

Efficacy and safety of native versus pegylated Escherichia coli asparaginase for treatment of adults with high-risk, Philadelphia chromosome-negative acute lymphoblastic leukemia.

PMID: 29165013
Journal: LEUKEMIA & LYMPHOMA
Year: 2018
Reference: Leuk Lymphoma. 2018 Jul;59(7):1634-1643. doi: 10.1080/10428194.2017.1397661. Epub 2017 Nov 22.
Impact factor:
Publication type: Paper in international publication
Authors: Abella, Eugenia; Amigo, Maria-Luz; Barba, Pere; Bergua, Juan; Bermudez, Arancha; Calbacho, Maria; Ciudad, Juana; Cladera, Antonia; Feliu, Evarist; Garcia-Belmonte, Daniel et al.
DOI: 10.1080/10428194.2017.1397661

Efficacy and Safety of Ticagrelor in Relation to Aspirin Use Within the Week Before Randomization in the SOCRATES Trial.

PMID: 29915123
Journal: STROKE
Year: 2018
Reference: Stroke. 2018 Jul;49(7):1678-1685. doi: 10.1161/STROKEAHA.118.020553. Epub 2018 Jun 18.
Impact factor: 6.239
Publication type: Clinical Trials
Authors: Ladenvall, Per, Minematsu, Kazuo, Molina, Carlos A, Wang, Yongjun, Johnston, S Claiborne, Knutsson, Mikael, Kasner, Scott E, Held, Peter, Wong, K S Lawrence, Amarenco, Pierre et al.
DOI: 10.1161/STROKEAHA.118.020553

Efficacy and Safety of Ticagrelor in Relation to Aspirin Use Within the Week Before Randomization in the SOCRATES Trial.

PMID: 29915123
Journal: STROKE
Year: 2018
Reference: Stroke. 2018 Jul;49(7):1678-1685. doi: 10.1161/STROKEAHA.118.020553. Epub 2018 Jun 18.
Impact factor:
Publication type: Clinical Trials
Authors: Albers, Gregory W; Amarenco, Pierre; Denison, Hans; Easton, J Donald; Evans, Scott R; Held, Peter; Himmelmann, Anders; Johnston, S Claiborne; Kasner, Scott E; Knutsson, Mikael et al.
DOI: 10.1161/STROKEAHA.118.020553

Efficacy and safety of topical application of 15% and 10% potassium hydroxide for the treatment of Molluscum contagiosum.

PMID: 29479727
Journal: PEDIATRIC DERMATOLOGY
Year: 2018
Reference: Pediatr Dermatol. 2018 May;35(3):336-342. doi: 10.1111/pde.13438. Epub 2018 Feb 26.
Impact factor: 1.041
Publication type: Paper in international publication
Authors: Diez, Olga, Marsal, Josep R, Giner-Soriano, Maria, Pera, Helena, Martinez, Mireia, Galindo-Ortego, Gisela, Schoenenberger, Joan A, Real, Jordi, Cruz, Ines, Morros, Rosa et al.
DOI: 10.1111/pde.13438

Efficacy and safety of topical application of 15% and 10% potassium hydroxide for the treatment of Molluscum contagiosum.

PMID: 29479727
Journal: PEDIATRIC DERMATOLOGY
Year: 2018
Reference: Pediatr Dermatol. 2018 May;35(3):336-342. doi: 10.1111/pde.13438. Epub 2018 Feb 26.
Impact factor:
Publication type: Paper in international publication
Authors: Cruz, Ines; Diez, Olga; Galindo-Ortego, Gisela; Giner-Soriano, Maria; Marsal, Josep R; Martinez, Mireia; Morros, Rosa; Pera, Helena; Real, Jordi; Schoenenberger, Joan A et al.
DOI: 10.1111/pde.13438

Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study).

PMID: 29632995
Journal: INTENSIVE CARE MEDICINE
Year: 2018
Reference: Intensive Care Med. 2018 Apr;44(4):438-448. doi: 10.1007/s00134-018-5143-7. Epub 2018 Apr 9.
Impact factor: 15.008
Publication type: Paper in international publication
Authors: Welte, Tobias, Dellinger, R Phillip, Ebelt, Henning, Ferrer, Miguel, Opal, Steven M, Singer, Mervyn, Vincent, Jean-Louis, Werdan, Karl, Martin-Loeches, Ignacio, Almirall, Jordi et al.
DOI: 10.1007/s00134-018-5143-7

Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study).

PMID: 29632995
Journal: INTENSIVE CARE MEDICINE
Year: 2018
Reference: Intensive Care Med. 2018 Apr;44(4):438-448. doi: 10.1007/s00134-018-5143-7. Epub 2018 Apr 9.
Impact factor:
Publication type: Paper in international publication
Authors: Achtzehn, Ute; Almirall, Jordi; Alvarez-Lerma, Francisco; Artigas, Antonio; Belohradsky, Bernd H; Bobenhausen, Iris; Bonastre Mora, Juan; Brealey, David; Brederlau, Jorg; Dalken, Benjamin et al.
DOI: 10.1007/s00134-018-5143-7

Efficacy of a Gluten-Free Diet in the Gilles de la Tourette Syndrome: A Pilot Study.

PMID: 29735930
Journal: Nutrients
Year: 2018
Reference: Nutrients. 2018 May 7;10(5). pii: nu10050573. doi: 10.3390/nu10050573.
Impact factor: 4.196
Publication type: Paper in international publication
Authors: Rodrigo, Luis, Alvarez, Nuria, Fernandez-Bustillo, Enrique, Salas-Puig, Javier, Huerta, Marcos, Hernandez-Lahoz, Carlos et al.
DOI: 10.3390/nu10050573

Efficacy of a Gluten-Free Diet in the Gilles de la Tourette Syndrome: A Pilot Study.

PMID: 29735930
Journal: Nutrients
Year: 2018
Reference: Nutrients. 2018 May 7;10(5). pii: nu10050573. doi: 10.3390/nu10050573.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez, Nuria; Fernandez-Bustillo, Enrique; Hernandez-Lahoz, Carlos; Huerta, Marcos; Rodrigo, Luis; Salas-Puig, Javier et al.
DOI: 10.3390/nu10050573

Efficacy of Idursulfase therapy in patients with Mucopolysaccharidosis type II who initiated enzyme replacement therapy in adult age. A systematic review of the literature.

PMID: 29801985
Journal: MOLECULAR GENETICS AND METABOLISM
Year: 2018
Reference: Mol Genet Metab. 2018 Jul;124(3):216-227. doi: 10.1016/j.ymgme.2018.04.013. Epub 2018 Apr 30.
Impact factor: 3.774
Publication type: Paper in international publication
Authors: Del Toro, M, Ceberio-Hualde, L, Munoz-Delgado, C, Perez-Lopez, J, Molto-Abad, M, Morales-Conejo, M et al.
DOI: 10.1016/j.ymgme.2018.04.013

Efficacy of Idursulfase therapy in patients with Mucopolysaccharidosis type II who initiated enzyme replacement therapy in adult age. A systematic review of the literature.

PMID: 29801985
Journal: MOLECULAR GENETICS AND METABOLISM
Year: 2018
Reference: Mol Genet Metab. 2018 Jul;124(3):216-227. doi: 10.1016/j.ymgme.2018.04.013. Epub 2018 Apr 30.
Impact factor:
Publication type: Paper in international publication
Authors: Ceberio-Hualde, L; Del Toro, M; Molto-Abad, M; Morales-Conejo, M; Munoz-Delgado, C; Perez-Lopez, J et al.
DOI: 10.1016/j.ymgme.2018.04.013

Efficacy of Sofosbuvir and Velpatasvir, With and Without Ribavirin, in Patients With HCV genotype 3 Infection and Cirrhosis.

PMID: 29958855
Journal: GASTROENTEROLOGY
Year: 2018
Reference: Gastroenterology. 2018 Oct;155(4):1120-1127.e4. doi: 10.1053/j.gastro.2018.06.042. Epub 2018 Jun 27.
Impact factor: 20.773
Publication type: Paper in international publication
Authors: Morano Amado, Luis Enrique, Morillas, Rosa Maria, Forns, Xavier, Pascasio Acevedo, Juan Manuel, Andrade, Raul J, Rivero, Antonio, Carrion, Jose Antonio, Lens, Sabela, Riveiro-Barciela, Mar, McNabb, Brian et al.
DOI: 10.1053/j.gastro.2018.06.042

Efficacy of Sofosbuvir and Velpatasvir, With and Without Ribavirin, in Patients With HCV genotype 3 Infection and Cirrhosis.

PMID: 29958855
Journal: GASTROENTEROLOGY
Year: 2018
Reference: Gastroenterology. 2018 Oct;155(4):1120-1127.e4. doi: 10.1053/j.gastro.2018.06.042. Epub 2018 Jun 27.
Impact factor:
Publication type: Paper in international publication
Authors: Andrade, Raul J; Brainard, Diana M; Buti, Maria; Calleja, Jose Luis; Camus, Gregory; Carrion, Jose Antonio; Casado, Marta; Esteban, Rafael; Forns, Xavier; Lens, Sabela et al.
DOI: 10.1053/j.gastro.2018.06.042

Efficacy of Sym004 in Patients With Metastatic Colorectal Cancer With Acquired Resistance to Anti-EGFR Therapy and Molecularly Selected by Circulating Tumor DNA Analyses: A Phase 2 Randomized Clinical Trial.

PMID: 29423521
Journal: JAMA Oncology
Year: 2018
Reference: JAMA Oncol. 2018 Apr 12;4(4):e175245. doi: 10.1001/jamaoncol.2017.5245. Epub 2018 Apr 12.
Impact factor: 20.871
Publication type: Paper in international publication
Authors: Desseigne, Francoise, Montagut, Clara, Argiles, Guillem, Ciardiello, Fortunato, Poulsen, Thomas T, Dienstmann, Rodrigo, Kragh, Michael, Kopetz, Scott, Lindsted, Trine, Ding, Cliff et al.
DOI: 10.1001/jamaoncol.2017.5245