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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Randomized phase II trial of FOLFIRI-panitumumab compared with FOLFIRI alone in patients with RAS wild-type circulating tumor DNA metastatic colorectal cancer beyond progression to first-line FOLFOX-panitumumab: the BEYOND study (GEMCAD 17-01).

PMID: 35761123
Journal: Clinical & Translational Oncology
Year: 2022
Reference: Clin Transl Oncol. 2022 Jun 27. pii: 10.1007/s12094-022-02868-x. doi: 10.1007/s12094-022-02868-x.
Impact factor: 3.405
Publication type: Paper in international publication
Authors: Vera, Ruth; Hernandez-Yague, Xavier; Gallego, Rafael Alvarez; Riesco-Martinez, M Carmen; Garcia de Albeniz, Xavier; Maurel, Joan; Serrano, Sara; Hernando, Jorge; Oliveres, Helena; Paez, David et al.
DOI: 10.1007/s12094-022-02868-x

Rapid and accurate method for quantifying busulfan in plasma samples by isocratic liquid chromatography-tandem mass spectrometry (LC-MS/MS)

PMID: NOPMID0100
Journal: Advances in Laboratory Medicine
Year: 2022
Reference: Adv Lab Med / Av en Med Lab. 2022;3(3):263-271. doi:10.1515/almed-2022-0016
Impact factor:
Publication type: Paper in national publication
Authors: Barquin Del Pino , Raquel ; Benitez Carabante, Maria Isabel ; Casis Saenz, Ernesto; Castellote Bellés, Laura; Ferrer Costa, Roser; López Hellin, Joan; Martinez Sánchez, Luisa; Miarons Font , Marta; Paciucci Barzanti, Rosanna; Rodríguez Frias, Francisco et al.
DOI: 10.1515/almed-2022-0016

Rapid and sustained B-cell depletion with subcutaneous ofatumumab in relapsing multiple sclerosis: APLIOS, a randomized phase-2 study.

PMID: 34605319
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 May;28(6):910-924. doi: 10.1177/13524585211044479. Epub 2021 Oct 4.
Impact factor: 6.312
Publication type: Paper in international publication
Authors: Bar-Or, Amit, Wiendl, Heinz, Montalban, Xavier, Alvarez, Enrique, Davydovskaya, Maria, Delgado, Silvia R, Evdoshenko, Evgeniy P, Giedraitiene, Natasa, Gross-Paju, Katrin, Haldre, Sulev et al.
DOI: 10.1177/13524585211044479

Rapidity of clinical response to adalimumab and improvement of quality of life in luminal Crohn’s disease: RAPIDA study

PMID: 34051313
Journal: Gastroenterologia y Hepatologia
Year: 2022
Reference: Gastroenterol Hepatol. 2022 Mar;45(3):165-176. doi: 10.1016/j.gastrohep.2021.04.010. Epub 2021 May 27.
Impact factor: 2.102
Publication type: Paper in national publication
Authors: Marin-Jimenez, Ignacio, de Acosta, Manuel Barreiro, Esteve, Maria, Castro-Laria, Luisa, Garcia-Lopez, Santiago, Ceballos, Daniel, Echarri, Ana, Martin-Arranz, Maria Dolores, Busquets, David, Llao, Jordina et al.
DOI: 10.1016/j.gastrohep.2021.04.010

Rates of Response to Atogepant for Migraine Prophylaxis Among Adults: A Secondary Analysis of a Randomized Clinical Trial.

PMID: 35675076
Journal: JAMA Network Open
Year: 2022
Reference: JAMA Netw Open. 2022 Jun 1;5(6):e2215499. doi: 10.1001/jamanetworkopen.2022.15499.
Impact factor: 8.485
Publication type: Paper in international publication
Authors: Li, Ye, Lu, Kaifeng, Lipton, Richard B, Pozo-Rosich, Patricia, Blumenfeld, Andrew M, Dodick, David W, McAllister, Peter, Miceli, Rosa, Trugman, Joel M, Finnegan, Michelle et al.
DOI: 10.1001/jamanetworkopen.2022.15499

Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery.

PMID: 35101083
Journal: Trials
Year: 2022
Reference: Trials. 2022 Jan 31;23(1):101. doi: 10.1186/s13063-021-05992-1.
Impact factor: 2.279
Publication type: Paper in international publication
Authors: Ofori, Sandra N, Marcucci, Maura, Painter, Thomas W, Conen, David, Leslie, Kate, Lomivorotov, Vladimir V, Sessler, Daniel, Chan, Matthew T V, Borges, Flavia K, Martinez Zapata, Maria J et al.
DOI: 10.1186/s13063-021-05992-1

Rationale and design of the pragmatic clinical trial tREatment with Beta-blockers after myOcardial infarction withOut reduced ejection fracTion (REBOOT).

PMID: 34351426
Journal: European Heart Journal-Cardiovascular Pharmacotherapy
Year: 2022
Reference: Eur Heart J Cardiovasc Pharmacother. 2022 May 5;8(3):291-301. doi: 10.1093/ehjcvp/pvab060.
Impact factor: 6.617
Publication type: Letter or abstract
Authors: Rossello, Xavier, Dominguez-Rodriguez, Alberto, Barrabes, Jose A, Sanchez, Pedro L, Anguita, Manuel, Fernandez-Vazquez, Felipe, Pascual-Figal, Domingo, De la Torre Hernandez, Jose M, Ferraro, Stefano, Vetrano, Alfredo et al.
DOI: 10.1093/ehjcvp/pvab060

Re: Magdalena Gortz, Jan Philipp Radtke, Gencay Hatiboglu, et al. The Value of Prostate-specific Antigen Density for Prostate Imaging-Reporting and Data System 3 Lesions on Multiparametric Magnetic Resonance Imaging: A Strategy to Avoid Unnecessary Prostate Biopsies. Eur Urol Focus 2021;7:325-31.

PMID: 34992001
Journal: European Urology Focus
Year: 2022
Reference: Eur Urol Focus. 2022 Jan 3. pii: S2405-4569(21)00318-7. doi: 10.1016/j.euf.2021.12.007.
Impact factor: 5.996
Publication type: Letter or abstract
Authors: Morote, Juan, Planas, Jacques, Trilla, Enrique et al.
DOI: 10.1016/j.euf.2021.12.007

Reaching a consensus on the definition of "difficult" cholecystectomy among Spanish experts. A Delphi project. A qualitative study.

PMID: 35525412
Journal: International Journal of Surgery
Year: 2022
Reference: Int J Surg. 2022 Jun;102:106649. doi: 10.1016/j.ijsu.2022.106649. Epub 2022 May 4.
Impact factor: 6.071
Publication type: Paper in international publication
Authors: Latorre-Fragua, Raquel, Alcazar, Candido, Requena, Paola Melgar, de la Plaza, Roberto, Blanco Fernandez, Gerardo, Serradilla-Martin, Mario, Ramia, J M, Cudrado, Martin Bailon, Blas Laina, Juan Luis, Suescun, Federico Castillo et al.
DOI: 10.1016/j.ijsu.2022.106649

REACT Aspiration Catheters: Clinical Experience and Technical Considerations.

PMID: 35718472
Journal: Neurointervention
Year: 2022
Reference: Neurointervention. 2022 Jul;17(2):70-77. doi: 10.5469/neuroint.2022.00255. Epub 2022 Jun 20.
Impact factor: 0
Publication type: Review in international publication
Authors: Li, Jiahui; Ribo, Marc et al.
DOI: 10.5469/neuroint.2022.00255

Real-Life Use of Ceftolozane/Tazobactam for the Treatment of Bloodstream Infection Due to Pseudomonas aeruginosa in Neutropenic Hematologic Patients: a Matched Control Study (ZENITH Study).

PMID: 35475683
Journal: Microbiology Spectrum
Year: 2022
Reference: Microbiol Spectr. 2022 Jun 29;10(3):e0229221. doi: 10.1128/spectrum.02292-21. Epub 2022 Apr 27.
Impact factor: 7.171
Publication type: Paper in international publication
Authors: Ruiz-Camps, Isabel, Bergas, Alba, Albasanz-Puig, Adaia, Fernandez-Cruz, Ana, Machado, Marina, Novo, Andres, van Duin, David, Garcia-Vidal, Carolina, Hakki, Morgan, Gudiol, Carlota et al.
DOI: 10.1128/spectrum.02292-21

Real-world analysis of main clinical outcomes in patients with polycythemia vera treated with ruxolitinib or best available therapy after developing resistance/intolerance to hydroxyurea.

PMID: 35417564
Journal: CANCER
Year: 2022
Reference: Cancer. 2022 Jul 1;128(13):2441-2448. doi: 10.1002/cncr.34195. Epub 2022 Apr 13.
Impact factor: 6.86
Publication type: Paper in international publication
Authors: Gasior, Mercedes, Alvarez-Larran, Alberto, Garrote, Marta, Ferrer-Marin, Francisca, Perez-Encinas, Manuel, Mata-Vazquez, M Isabel, Bellosillo, Beatriz, Arellano-Rodrigo, Eduardo, Gomez, Montse, Garcia, Regina et al.
DOI: 10.1002/cncr.34195

Real-world evidence of brexucabtagene autoleucel for the treatment of relapsed or refractory mantle cell lymphoma.

PMID: 35271707
Journal: Blood Advances
Year: 2022
Reference: Blood Adv. 2022 Jun 28;6(12):3606-3610. doi: 10.1182/bloodadvances.2021006922.
Impact factor: 6.799
Publication type: Letter whit IF
Authors: Reguera-Ortega, Juan Luis, Camacho-Arteaga, Lina, Schmidt, Christian, Marin-Niebla, Ana, Kersten, Marie Jose, Martin Garcia-Sancho, Alejandro, Zinzani, Pier Luigi, Corradini, Paolo, van Meerten, Tom, Subklewe, Marion et al.
DOI: 10.1182/bloodadvances.2021006922

Real-World Evidence of Daratumumab Monotherapy in Relapsed/Refractory Multiple Myeloma Patients and Efficacy on Soft-Tissue Plasmacytomas.

PMID: 35610120
Journal: Clinical Lymphoma Myeloma & Leukemia
Year: 2022
Reference: Clin Lymphoma Myeloma Leuk. 2022 Apr 17. pii: S2152-2650(22)00126-4. doi: 10.1016/j.clml.2022.04.014.
Impact factor: 3.231
Publication type: Paper in international publication
Authors: Granell, Miquel, Abella, Eugenia, Garcia-Pintos, Marta, Garcia-Guinon, Antoni, Cabezudo, Elena, Blade, Joan, Rosinol, Laura, Motllo, Cristina, Gironella, Mercedes, Soler, Juan Alfons et al.
DOI: 10.1016/j.clml.2022.04.014

Recent concepts in fungal involvement in skin and soft tissue infections.

PMID: 34861654
Journal: CURRENT OPINION IN INFECTIOUS DISEASES
Year: 2022
Reference: Curr Opin Infect Dis. 2022 Apr 1;35(2):103-111. doi: 10.1097/QCO.0000000000000806.
Impact factor: 4.915
Publication type: Review in international publication
Authors: Peghin, Maddalena, Ruiz-Camps, Isabel et al.
DOI: 10.1097/QCO.0000000000000806

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia.

PMID: 35708626
Journal: JOURNAL OF EXPERIMENTAL MEDICINE
Year: 2022
Reference: J Exp Med. 2022 Aug 1;219(8). pii: 213287. doi: 10.1084/jem.20220131. Epub 2022 Jun 16.
Impact factor: 14.307
Publication type: Paper in international publication
Authors: El Baghdadi, Jamila, Bohlen, Jonathan, Liu, Zhiyong, Moncada-Velez, Marcela, Kendir-Demirkol, Yasemin, Jing, Huie, Bizien, Lucy, Marchal, Astrid, Abolhassani, Hassan, Delafontaine, Selket et al.
DOI: 10.1084/jem.20220131

Recommendations by the Spanish Society of Rheumatology on Fibromyalgia. Part 1: Diagnosis and treatment.

PMID: 34649820
Journal: Reumatologia clinica
Year: 2022
Reference: Reumatol Clin. 2022 Mar;18(3):131-140. doi: 10.1016/j.reumae.2021.02.002. Epub 2021 Oct 11.
Impact factor: 0
Publication type: Paper in international publication
Authors: Rivera Redondo, Javier, Diaz Del Campo Fontecha, Petra, Alegre de Miquel, Cayetano, Almirall Bernabe, Miriam, Casanueva Fernandez, Benigno, Castillo Ojeda, Cristina, Collado Cruz, Antonio, Monteso-Curto, Pilar, Palao Tarrero, Angela, Trillo Calvo, Eva et al.
DOI: 10.1016/j.reuma.2021.02.004

Recommendations by the Spanish Society of Rheumatology on the management of patients with fibromyalgia. Part II.

PMID: 34538611
Journal: Reumatologia clinica
Year: 2022
Reference: Reumatol Clin. 2022 May;18(5):260-265. doi: 10.1016/j.reumae.2021.01.005. Epub 2021 Sep 15.
Impact factor: 0
Publication type: Paper in national publication
Authors: Trillo Calvo, Eva, Rivera Redondo, Javier, Diaz Del Campo Fontecha, Petra, Alegre de Miquel, Cayetano, Almirall Bernabe, Miriam, Casanueva Fernandez, Benigno, Castillo Ojeda, Cristina, Collado Cruz, Antonio, Monteso-Curto, Pilar, Palao Tarrero, Angela et al.
DOI: 10.1016/j.reuma.2021.01.006

Recommendations for the diagnosis and treatment of patients with thrombotic thrombocytopenic purpura.

PMID: 34266669
Journal: MEDICINA CLINICA
Year: 2022
Reference: Med Clin (Barc). 2022 Jun 24;158(12):630.e1-630.e14. doi: 10.1016/j.medcli.2021.03.040. Epub 2021 Jul 12.
Impact factor: 1.725
Publication type: Paper in national publication
Authors: Mingot Castellano, Maria Eva, Pascual Izquierdo, Cristina, Gonzalez, Ataulfo, Viejo Llorente, Aurora, Valcarcel Ferreiras, David, Sebastian, Elena, Gomez Segui, Ines, de la Rubia, Javier, Cid, Joan, Martinez Nieto, Jorge et al.
DOI: 10.1016/j.medcli.2021.03.040

[Recommendations for the management of critically ill patients with COVID-19 in Intensive Care Units].

PMID: 34545260
Journal: Medicina Intensiva
Year: 2022
Reference: Med Intensiva. 2022 Feb;46(2):81-89. doi: 10.1016/j.medin.2021.08.011. Epub 2021 Sep 16.
Impact factor: 2.491
Publication type: Paper in national publication
Authors: Carlos Igeno Cano, Jose, Posadilla, David Iglesias, Rivera, Juan Jose Jimenez, Jorge, Celina Llanos, Llompart-Pou, Juan Antonio, Camps, Vicent Lopez, Cardenas, Carol Lorencio, Neira, Pilar Marcos, Delgado, Maria Cruz Martin, Gonzalez, Mercedes Martin-Macho et al.
DOI: 10.1016/j.medin.2021.08.011

Recommendations for the management of critically ill patients with COVID-19 in Intensive Care Units.

PMID: 34903475
Journal: Medicina Intensiva
Year: 2022
Reference: Med Intensiva (Engl Ed). 2022 Feb;46(2):81-89. doi: 10.1016/j.medine.2021.11.019. Epub 2021 Dec 10.
Impact factor: 2.491
Publication type: Paper in international publication
Authors: Estella, A; Vidal-Cortes, P; Diaz Santos, E; Aguilar Alonso, E; Amezaga Menendez, R; Ballesteros, M A; Bodi, M A; Bordeje Laguna, M L; Garnacho Montero, J; Garcia Sanchez, M et al.
DOI: 10.1016/j.medine.2021.11.019

Recommendations for the use of biomarkers for head and neck cancer, including salivary gland tumours: a consensus of the Spanish Society of Medical Oncology and the Spanish Society of Pathology.

PMID: 35739348
Journal: Clinical & Translational Oncology
Year: 2022
Reference: Clin Transl Oncol. 2022 Jun 23. pii: 10.1007/s12094-022-02856-1. doi: 10.1007/s12094-022-02856-1.
Impact factor: 3.405
Publication type: Paper in international publication
Authors: Garcia-Castano, Almudena; Goma, Montserrat; Mesia-Nin, Ricard; Ruiz-Bravo, Elena; Soria-Rivas, Ainara; Castillo, Paola; Brana-Garcia, Irene; Alberola-Ferranti, Margarita; Garcia-Cosio, Monica; Trigo, Jose et al.
DOI: 10.1007/s12094-022-02856-1

Recommendations of high-quality clinical practice guidelines related to the process of starting dialysis: A systematic review.

PMID: 35696388
Journal: PLoS One
Year: 2022
Reference: PLoS One. 2022 Jun 13;17(6):e0266202. doi: 10.1371/journal.pone.0266202. eCollection 2022.
Impact factor: 3.24
Publication type: Review in international publication
Authors: Heneghan, Carl J, Coronado Daza, Jorge, Salas-Gama, Karla, Onakpoya, Igho J, Perera, Rafael et al.
DOI: 10.1371/journal.pone.0266202

Recommendations of the Society of Thoracic Surgery and the Section of Cardiothoracic and Vascular Surgery of the Spanish Society of Anesthesia, Resuscitation and Pain Therapy, for patients undergoing lung surgery included in an intensified recovery program.

PMID: 35585017
Journal: Revista espanola de anestesiologia y reanimacion
Year: 2022
Reference: Rev Esp Anestesiol Reanim (Engl Ed). 2022 Apr;69(4):208-241. doi: 10.1016/j.redare.2021.02.011. Epub 2022 May 15.
Impact factor: 0
Publication type: Review in international publication
Authors: Pineiro, P, Cruz, P, de la Gala, F, Quero, F, Huerta, L J, Rodriguez, M, Jimenez, E, Puente-Maestu, L, Aragon, S, Osorio-Salazar, E et al.
DOI: 10.1016/j.redare.2021.02.011