About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Research Group on Status Epilepticus and Acute Seizures is a young and emerging team, consolidated in national and international clinical research and in the comprehensive and multidisciplinary approach to epilepsy. The scientific challenge of the group is based on understanding, improving and strengthening knowledge about the different fields of epilepsy and how to help solve problems related to epileptic seizures and their consequences.
Among the different projects of the group, it is worth mentioning the search for new biomarkers related to the mechanisms of epileptogenesis, obtaining tools and biomarkers to help diagnose status epilepticus and predict its prognosis, the acquisition of neuroimaging parameters and their relationship with the cognitive status of patients, and other studies to accelerate the diagnostic processes and optimize the therapeutic management of patients with drug-resistant epilepsy.
PMID: 37589724 Journal: ACTA NEUROCHIRURGICA Year: 2023 Reference: Acta Neurochir (Wien). 2023 Aug 17. doi: 10.1007/s00701-023-05739-8. Impact factor: Publication type: Paper in international publication Authors: Arikan, Fuat; Coscojuela, Pilar; De Barros, Andrea; Dinia, Lavinia; Gandara, Dario; Gramegna, Laura Ludovica; Hernandez, David; Luzi, Michele; Martinez-Saez, Elena; Quintana, Manuel et al. DOI: 10.1007/s00701-023-05739-8
PMID: 37684497 Journal: CNS DRUGS Year: 2023 Reference: CNS Drugs. 2023 Sep 9. doi: 10.1007/s40263-023-01033-4. Impact factor: Publication type: Paper in international publication Authors: Besson, Herve; Chinn, Chris; D'Souza, Wendyl; Daniels, Tony; Faught, Edward; Floricel, Florin; Friesen, David; Insuga, Victor Soto; Klein, Pavel; Laloyaux, Cedric et al. DOI: 10.1007/s40263-023-01033-4
PMID: 37804071 Journal: EPILEPSIA Year: 2023 Reference: Epilepsia. 2023 Oct 7. doi: 10.1111/epi.17790. Impact factor: Publication type: Letter or abstract Authors: Abraira, Laura; Abraira, Laura; Campos-Fernandez, Daniel; Campos-Fernandez, Daniel; Fonseca, Elena; Fonseca, Elena; Gomez-Dabo, Laura; Lallana, Sofia; Quintana, Manuel; Quintana, Manuel et al. DOI: 10.1111/epi.17790
PMID: 37858895 Journal: Neurologia Year: 2023 Reference: Neurologia (Engl Ed). 2023 Oct 17:S2173-5808(23)00054-8. doi: 10.1016/j.nrleng.2021.02.010. Impact factor: Publication type: Paper in international publication Authors: Abraira, L; Ballve, A; Campos, D; Costa E Silva, Matheus; Dienstmann, Rodrigo; Fonseca, E; Gil Ferreira, Carlos; Llaurado, A; Lopes David, Bruna Bianca; Nazareth Aguiar Junior, Pedro et al. DOI: 10.1016/j.nrleng.2021.02.010
PMID: 34813673 Journal: EPILEPSIA Year: 2022 Reference: Epilepsia. 2022 Jan;63(1):139-149. doi: 10.1111/epi.17134. Epub 2021 Nov 23. Impact factor: Publication type: Paper in international publication Authors: Biton, Victor; Halford, Jonathan J; Rosenfeld, William E; Sander, Josemir W; Steinhoff, Bernhard J; Toledo, Manuel et al. DOI: 10.1111/epi.17134
PMID: 34988947 Journal: ACTA NEUROLOGICA BELGICA Year: 2022 Reference: Acta Neurol Belg. 2022 Jun;122(3):823-825. doi: 10.1007/s13760-021-01864-2. Epub 2022 Jan 6. Impact factor: Publication type: Letter or abstract Authors: Auger, Cristina; Callejo, Ana; Cobo-Calvo, Alvaro; Lallana, Sofia; Rio, Jordi; Sanchez-Tejerina, Daniel et al. DOI: 10.1007/s13760-021-01864-2
PMID: 34687043 Journal: ACTA NEUROLOGICA SCANDINAVICA Year: 2022 Reference: Acta Neurol Scand. 2022 Feb;145(2):239-248. doi: 10.1111/ane.13543. Epub 2021 Oct 22. Impact factor: Publication type: Paper in international publication Authors: Abraira, Laura; Alvarez-Sabin, Jose; Fonseca, Elena; Ortiz de Zarate, Zurine; Quintana, Manuel; Santamarina, Estevo; Seijo-Raposo, Ivan; Toledo, Manuel et al. DOI: 10.1111/ane.13543
PMID: 34390102 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2022 Reference: Eur J Neurol. 2022 Jan;29(1):3-11. doi: 10.1111/ene.15065. Epub 2021 Sep 3. Impact factor: Publication type: Paper in international publication Authors: Auger, C; Pareto, D; Quintana, M; Rovira, A; Santamarina, E; Sarria-Estrada, S; Sueiras, M; Toledo, M et al. DOI: 10.1111/ene.15065
PMID: 34509033 Journal: EPILEPSY & BEHAVIOR Year: 2021 Reference: Epilepsy Behav. 2021 Oct;123:108270. doi: 10.1016/j.yebeh.2021.108270. Epub 2021 Sep 8. Impact factor: Publication type: Paper in international publication Authors: Brandt, Christian; Klein, Pavel; Krauss, Gregory L; Rosenfeld, William E; Serratosa, Jose M; Steinhoff, Bernhard J; Toledo, Manuel et al. DOI: 10.1016/j.yebeh.2021.108270
PMID: 34505305 Journal: ANNALS OF NEUROLOGY Year: 2021 Reference: Ann Neurol. 2021 Nov;90(5):808-820. doi: 10.1002/ana.26212. Epub 2021 Sep 30. Impact factor: Publication type: Paper in international publication Authors: Abraira, Laura; Alvarez-Sabin, Jose; Bentes, Carla; Bicciato, Giulio; Brigo, Francesco; Conrad, Julian; Dohler, Nico; Duncan, John S; Erdelyi-Canavese, Barbara; Evers, Stefan et al. DOI: 10.1002/ana.26212
PMID: 34375799 Journal: EPILEPSY & BEHAVIOR Year: 2021 Reference: Epilepsy Behav. 2021 Oct;123:108238. doi: 10.1016/j.yebeh.2021.108238. Epub 2021 Aug 7. Impact factor: Publication type: Paper in international publication Authors: Abraira, Laura; Alvarez-Sabin, Jose; Delgado, Pilar; Fonseca, Elena; Jimenez-Balado, Joan; Maisterra, Olga; Quintana, Manuel; Salas-Puig, Xavier; Santamarina, Estevo; Toledo, Manuel et al. DOI: 10.1016/j.yebeh.2021.108238
PMID: 34371462 Journal: EPILEPSY & BEHAVIOR Year: 2021 Reference: Epilepsy Behav. 2021 Sep;122:108222. doi: 10.1016/j.yebeh.2021.108222. Epub 2021 Aug 6. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Baron, Elena; Carreno, Mar; Gil, Alicia; Gil-Nagel, Antonio; Serrano-Castro, Pedro Jesus; Serratosa, Jose Maria; Subias-Labazuy, Silvia; Toledo, Manuel; Villanueva, Vicente et al. DOI: 10.1016/j.yebeh.2021.108222
PMID: 32614067 Journal: ACTA NEUROLOGICA SCANDINAVICA Year: 2020 Reference: Acta Neurol Scand. 2020 Dec;142(6):555-562. doi: 10.1111/ane.13302. Epub 2020 Jul 29. Impact factor: Publication type: Paper in international publication Authors: Caronna, Edoardo; Gracia Gozalo, Rosa Maria; Guzman, Lorena; Quintana, Manuel; Sanchez Corral, Anna; Santafe, Manel; Santamarina, Estevo; Sueiras, Maria; Toledo-Argany, Manuel; Vilaseca, Andreu et al. DOI: 10.1111/ane.13302
PMID: 32540769 Journal: EPILEPSY & BEHAVIOR Year: 2020 Reference: Epilepsy Behav. 2020 Jun 5;111:107211. doi: 10.1016/j.yebeh.2020.107211. Impact factor: Publication type: Paper in international publication Authors: Betran, Olga; Carreno, Mar; Centeno, Maria; Conde-Blanco, Estefania; Donaire, Antonio; Garcia-Penas, Juan Jose; Jimenez, Angeles Perez; Manzanares, Isabel; Muriana, Desiree; Nagel, Antonio Gil et al. DOI: 10.1016/j.yebeh.2020.107211
PMID: 32511754 Journal: EPILEPSIA Year: 2020 Reference: Epilepsia. 2020 Jun;61(6):1109-1119. doi: 10.1111/epi.16548. Epub 2020 Jun 8. Impact factor: Publication type: Paper in international publication Authors: Aguilar-Amat Prior, Maria Jose; Ayuga Loro, Fernando; Campos, Dulce; Castro-Vilanova, Maria Dolores; Estevez Maria, Jose Carlos; Garcia-Barragan, Nuria; Garcia-Morales, Irene; Gil-Nagel, Antonio; Giner, Pau; Gomez-Ibanez, Asier et al. DOI: 10.1111/epi.16548
PMID: 32155575 Journal: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY Year: 2020 Reference: Seizure. 2020 May;78:31-37. doi: 10.1016/j.seizure.2020.02.018. Epub 2020 Mar 5. Impact factor: Publication type: Review in international publication Authors: Akamatsu, Naoki; Bast, Thomas; Bauer, Sebastian; Baumgartner, Christoph; Benbadis, Selim; Bermeo-Ovalle, Adriana; Beyenburg, Stefan; Bleasel, Andrew; Bozorgi, Alireza; Brazdil, Milan et al. DOI: 10.1016/j.seizure.2020.02.018
PMID: 31079028 Journal: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY Year: 2019 Reference: Seizure. 2019 Jul;69:198-203. doi: 10.1016/j.seizure.2019.04.021. Epub 2019 May 1. Impact factor: Publication type: Paper in international publication Authors: Abraira, Laura; Cazorla, Sonia; Mazuela, Gonzalo; Quintana, Manuel; Santamarina, Estevo; Toledo, Manuel et al. DOI: 10.1016/j.seizure.2019.04.021
PMID: 31072248 Journal: INTERVENTIONAL NEURORADIOLOGY Year: 2019 Reference: Interv Neuroradiol. 2019 Oct;25(5):491-496. doi: 10.1177/1591019919847623. Epub 2019 May 9. Impact factor: Publication type: Paper in international publication Authors: Aixut, Sonia; Coscojuela, Pilar; Dinia, Lavinia; Gramegna, Laura Ludovica; Hernandez, David; Lopez-Rueda, Antonio; Luttich, Alexandre; Melendez, Fernando; Moreu, Manuel; Quintana, Manuel et al. DOI: 10.1177/1591019919847623
PMID: 30953593 Journal: ACTA NEUROLOGICA SCANDINAVICA Year: 2019 Reference: Acta Neurol Scand. 2019 Jul;140(1):48-55. doi: 10.1111/ane.13099. Epub 2019 May 9. Impact factor: Publication type: Paper in international publication Authors: Castro-Vilanova, Dolores; Gomez-Eguilaz, Maria; Mauri, Jose Angel; Mazuela, Gonzalo; Rodriguez-Osorio, Xiana; Rodriguez-Uranga, Juan; Santamarina, Estevo; Toledo, Manuel et al. DOI: 10.1111/ane.13099
PMID: 30834194 Journal: Epilepsy & behavior case reports Year: 2019 Reference: Epilepsy Behav Case Rep. 2019 Feb 7;11:92-95. doi: 10.1016/j.ebcr.2019.01.008. eCollection 2019. Impact factor: Publication type: Paper in international publication Authors: Abraira, Laura; Alpuente, Alicia; Guzman, Lorena; Maisterra, Olga; Salas-Puig, Javier; Santamarina, Estevo; Sarria, Silvana; Sueiras, Maria; Toledo, Manuel et al. DOI: 10.1016/j.ebcr.2019.01.008
PMID: 30047129 Journal: EPILEPSIA Year: 2018 Reference: Epilepsia. 2018 Sep;59(9):1727-1739. doi: 10.1111/epi.14520. Epub 2018 Jul 25. Impact factor: Publication type: Paper in international publication Authors: Ben-Menachem, Elinor; Bertol-Alegre, Vicente; Brodie, Martin J; Carpenter, Katherine J; Di Gennaro, Giancarlo; Garamendi, Inigo; Garcia-Morales, Irene; Lopez-Gonzalez, Francisco Javier; Maurousset, Aude; Menzler, Katja et al. DOI: 10.1111/epi.14520
PMID: 30041081 Journal: EPILEPSY RESEARCH Year: 2018 Reference: Epilepsy Res. 2018 Sep;145:169-177. doi: 10.1016/j.eplepsyres.2018.07.003. Epub 2018 Jul 21. Impact factor: Publication type: Paper in international publication Authors: Brewer, M Kathryn; Garcia-Gimeno, Maria Adelaida; Gentry, Matthew S; Rodilla-Ramirez, Pilar Natalia; Salas-Puig, Xavier; Sanz, Pascual; Viana, Rosa et al. DOI: 10.1016/j.eplepsyres.2018.07.003
PMID: 30015150 Journal: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY Year: 2018 Reference: Seizure. 2018 Aug;60:172-177. doi: 10.1016/j.seizure.2018.07.006. Epub 2018 Jul 9. Impact factor: Publication type: Paper in international publication Authors: Abraira, Laura; Gonzalez-Cuevas, Montserrat; Guzman, Lorena; Maisterra, Olga; Quintana, Manuel; Sabin, Jose Alvarez; Salas-Puig, Javier; Santamarina, Estevo; Sueiras, Maria; Toledo, Manuel et al. DOI: 10.1016/j.seizure.2018.07.006
PMID: 29790568 Journal: REVISTA DE NEUROLOGIA Year: 2018 Reference: Rev Neurol. 2018 Jun 1;66(11):361-367. Impact factor: Publication type: Paper in national publication Authors: Abraira, L; Ortega, G; Quintana, M; Salas-Puig, J; Sanabria, A; Santamarina, E; Toledo, M et al. DOI:
PMID: 26541696 Journal: NEUROLOGIA Year: 2017 Reference: Neurologia. 2017 Apr;32(3):152-157. doi: 10.1016/j.nrl.2015.08.001. Epub 2015 Nov 2. Impact factor: Publication type: Paper in national publication Authors: Aller-Alvarez, J S; Alvarez-Sabin, J; Quintana, M; Santamarina, E et al. DOI: 10.1016/j.nrl.2015.08.001
PMID: 28301586 Journal: PLoS One Year: 2017 Reference: PLoS One. 2017 Mar 16;12(3):e0174092. doi: 10.1371/journal.pone.0174092. eCollection 2017. Impact factor: Publication type: Paper in international publication Authors: Canela, Merce; Carmona, Francesc; Deu, Maria; Gamez, Josep; Laborda, Cesar; Martinez-de La Ossa, Alejandro; Nadal, Miriam; Raguer, Nuria; Rochera, Isabel; Roman, Antonio et al. DOI: 10.1371/journal.pone.0174092
PMID: 27889312 Journal: LANCET NEUROLOGY Year: 2017 Reference: Lancet Neurol. 2017 Jan;16(1):43-54. doi: 10.1016/S1474-4422(16)30292-7. Epub 2016 Nov 24. Impact factor: Publication type: Clinical Trials Authors: Baulac, Michel; Brock, Melissa; De Backer, Marc; Li, Ting; Rosenow, Felix; Terada, Kiyohito; Toledo, Manuel; Werhahn, Konrad J et al. DOI: 10.1016/S1474-4422(16)30292-7
PMID: 28074997 Journal: REVISTA DE NEUROLOGIA Year: 2017 Reference: Rev Neurol. 2017 Jan 16;64(2):49-54. Impact factor: Publication type: Paper in national publication Authors: Gonzalez-Cuevas, M; Quintana, M; Raspall-Chaure, M; Sala-Padro, J; Salas-Puig, J; Santamarina, E; Sueiras-Gil, M; Toledo, M et al. DOI: 10.33588/rn.6402.2016219
PMID: 27521586 Journal: EPILEPSY RESEARCH Year: 2016 Reference: Epilepsy Res. 2016 Oct;126:201-10. doi: 10.1016/j.eplepsyres.2016.08.001. Epub 2016 Aug 4. Impact factor: Publication type: Paper in international publication Authors: Baiges, J J; Camacho, J L; Campos, D; Carreno, M; Castillo, A; Esteve, P; Flores, J; Garces, M; Giner, P; Gomez, J B et al. DOI: 10.1016/j.eplepsyres.2016.08.001
PMID: 26944271 Journal: NEUROLOGY Year: 2016 Reference: Neurology. 2016 Mar 29;86(13):1250-9. doi: 10.1212/WNL.0000000000002526. Epub 2016 Mar 4. Impact factor: Publication type: Paper in international publication Authors: Ambrosetto, Giovanni; Barba, Carmen; Bartolini, Emanuele; Cosottini, Mirco; Falchi, Melania; Ferrari, Anna Rita; Grisotto, Laura; Guerrini, Renzo; Parmeggiani, Antonia; Parrini, Elena et al. DOI: 10.1212/WNL.0000000000002526
PMID: 26419969 Journal: STROKE Year: 2015 Reference: Stroke. 2015 Nov;46(11):3149-53. doi: 10.1161/STROKEAHA.115.010608. Epub 2015 Sep 29. Impact factor: Publication type: Paper in international publication Authors: Boned, Sandra; Carcamo, Daniel; Coscojuela, Pilar; Flores, Alan; Lemus, Miguel; Meler, Pilar; Molina, Carlos A; Muchada, Marian; Pagola, Jorge; Ribo, Marc et al. DOI: 10.1161/STROKEAHA.115.010608
PMID: 26286206 Journal: EPILEPSY BEHAV Year: 2015 Reference: Epilepsy Behav Case Rep. 2015 Aug 8;4:56-9. doi: 10.1016/j.ebcr.2015.06.007. eCollection 2015. Impact factor: Publication type: Paper in international publication Authors: Baneras, Jordi; Gonzalez, Montserrat; Guzman, Lorena; Lidon, Rosa M; Salas-Puig, Xavier; Santamarina, Estevo; Sueiras, Maria; Toledo, Manuel et al. DOI: 10.1016/j.ebcr.2015.06.007
PMID: 26071995 Journal: EPILEPSY BEHAV Year: 2015 Reference: Epilepsy Behav. 2015 Aug;49:280-5. doi: 10.1016/j.yebeh.2015.04.032. Epub 2015 Jun 10. Impact factor: Publication type: Paper in international publication Authors: Becerra, J L; Carreno, M; Escofet, C; Falip, M; Fossas, P; Gaig, C; Ley, M; Miro, J; Molins, A; Muriana, D et al. DOI: 10.1016/j.yebeh.2015.04.032
