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Rheumatology

The Rheumatology Research Group (GRR) is focused on translational research in immunity-mediated inflammatory diseases (IMIDA), mainly in the area of rheumatology. The GRR is a multidisciplinary group made up of clinical specialists, biologists, bioinformaticians and laboratory technicians. The different research lines of the GRR emphasize the use of high-performance technologies for the study at the cellular and molecular level of the immununopathology of IMIDA, mainly chronic inflammatory arthritis and autoimmune systemic diseases.

At the clinical level, we have developed lines of research in very diverse areas of rheumatology, including chronic inflammatory arthritis (rheumatoid arthritis, spondyloarthropathies), systemic autoimmune diseases (lupus, myositis, Sjögren's syndrome), the study of musculoskeletal imaging, pediatric rheumatology (juvenile idiopathic arthritis, autoimmune systemic diseases, autoinflammatory syndromes), central sensitization syndromes and the study of bone metabolism. One of the main objectives of the GRR is the coordination of basic and clinical research to accelerate the transfer of knowledge to clinical practice and thus improve the quality of life of patients.

Team

Miriam Almirall Bernabé

Miriam Almirall Bernabé

Rheumatology
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Montse Sender Beleta

Montse Sender Beleta

Research technician
Rheumatology
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Nuria Palau Balaña

Nuria Palau Balaña

Research technician
Rheumatology
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Rafael Touriño García

Rafael Touriño García

Predoctoral researcher
Rheumatology
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Alcaraz Lopez, Carlos Jorge

Alcaraz Lopez, Carlos Jorge

Rheumatology
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Mariona Colom Saborit

Mariona Colom Saborit

Research technician
Rheumatology
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Miriam Almirall Bernabé

Miriam Almirall Bernabé

Rheumatology
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Montse Sender Beleta

Montse Sender Beleta

Research technician
Rheumatology
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Nuria Palau Balaña

Nuria Palau Balaña

Research technician
Rheumatology
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Rafael Touriño García

Rafael Touriño García

Predoctoral researcher
Rheumatology
Read more
Alcaraz Lopez, Carlos Jorge

Alcaraz Lopez, Carlos Jorge

Rheumatology
Read more
Mariona Colom Saborit

Mariona Colom Saborit

Research technician
Rheumatology
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Publications

Personalized Management of Fatigue in Individuals With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Long COVID Using a Smart Digital mHealth Solution: Protocol for a Participatory Design Approach.

PMID: 38608263
Journal:
Year: 2024
Reference: JMIR Res Protoc. 2024 Apr 12;13:e50157. doi: 10.2196/50157.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre-Martin, Jose; Bejar Prado, Luis; Castro-Marrero, Jesus; Dolores Hernandez, Maria; Dorronzoro-Zubiete, Enrique; Lacalle-Remigio, Juan R; Launois-Obregon, Patricia; Luque Budia, Asuncion; Martin-Garrido, Isabel; Rivera Romero, Octavio et al.
DOI: 10.2196/50157

Precise Targeting of Autoantigen-Specific B Cells in Lupus Nephritis with Chimeric Autoantibody Receptor T Cells.

PMID: 38673811
Journal:
Year: 2024
Reference: Int J Mol Sci. 2024 Apr 11;25(8):4226. doi: 10.3390/ijms25084226.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, Josefina; Gabaldon, Alejandra; Moline, Teresa; Royo, Maria; Sandoval, Sebastian; Sole, Cristina et al.
DOI: 10.3390/ijms25084226

A Narrative Review on Gut Microbiome Disturbances and Microbial Preparations in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Implications for Long COVID.

PMID: 38892479
Journal: Nutrients
Year: 2024
Reference: Nutrients. 2024 May 21;16(11):1545. doi: 10.3390/nu16111545.
Impact factor:
Publication type: Paper in international publication
Authors: Castro-Marrero, Jesus; Jurek, Joanna Michalina et al.
DOI: 10.3390/nu16111545

Pathological autoantibody internalisation in myositis.

PMID: 38902010
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2024
Reference: Ann Rheum Dis. 2024 Jun 20:ard-2024-225773. doi: 10.1136/ard-2024-225773.
Impact factor:
Publication type: Paper in international publication
Authors: Aldecoa, Iban; Cano, Maria Dolores; Casal-Dominguez, Maria; Christopher-Stine, Lisa; Dell'Orso, Stefania; Espinosa, Gerard; Garrabou, Gloria; Gil-Vila, Albert; Grau, Josep Maria; Greenberg, Steven A et al.
DOI: 10.1136/ard-2024-225773

Reply.

PMID: 36777496
Journal: MEDICINA CLINICA
Year: 2023
Reference: Med Clin (Engl Ed). 2023 Feb 10;160(3):140-141. doi: 10.1016/j.medcle.2022.10.008. Epub 2023 Feb 4.
Impact factor:
Publication type: Letter or abstract
Authors: Canas-Ruano, Esperanza; Fernandez-Codina, Andreu; Sempere-Gonzalez, Abiu et al.
DOI: 10.1016/j.medcle.2022.10.008

Transcriptomic profiling reveals distinct subsets of immune checkpoint inhibitor induced myositis.

PMID: 36801811
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2023
Reference: Ann Rheum Dis. 2023 Jun;82(6):829-836. doi: 10.1136/ard-2022-223792. Epub 2023 Feb 17.
Impact factor:
Publication type: Paper in international publication
Authors: Casal-Dominguez, Maria; Christopher-Stine, Lisa; Dell'Orso, Stefania; Derfoul, Assia; Duque-Jaimez, Yaiza; Garrabou, Gloria; Grau-Junyent, Josep Maria; Gutierrez-Cruz, Gustavo; Liewluck, Teerin; Lloyd, Thomas E et al.
DOI: 10.1136/ard-2022-223792

Expected impact of immunomodulatory agents during pregnancy: A newborn's perspective.

PMID: 36825745
Journal: PEDIATRIC ALLERGY AND IMMUNOLOGY
Year: 2023
Reference: Pediatr Allergy Immunol. 2023 Feb;34(2):e13911. doi: 10.1111/pai.13911.
Impact factor:
Publication type: Review in international publication
Authors: Acevedo, Daniel; Alsina, Laia; Anton, Jordi; Banos, Nuria; Casellas, Manel; Castellanos-Moreira, Raul; Deya-Martinez, Angela; Esteve-Sole, Ana; Garcia-Garcia, Ana; Grados, Dolors et al.
DOI: 10.1111/pai.13911

Transcriptional derepression of CHD4/NuRD-regulated genes in the muscle of patients with dermatomyositis and anti-Mi2 autoantibodies.

PMID: 37130727
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2023
Reference: Ann Rheum Dis. 2023 May 2:ard-2023-223873. doi: 10.1136/ard-2023-223873.
Impact factor:
Publication type: Paper in international publication
Authors: Albayda, Jemima; Casal-Dominguez, Maria; Christopher-Stine, Lisa; Dell'Orso, Stefania; Duque-Jaimez, Yaiza; Garcia-Garcia, Francesc J; Garrabou, Gloria; Grau-Junyent, Josep Maria; Guitart-Mampel, Mariona; Gutierrez-Cruz, Gustavo et al.
DOI: 10.1136/ard-2023-223873

Effectiveness and safety of bisphosphonates therapy in secondary osteoporosis in children.

PMID: 35915035
Journal: ANALES DE PEDIATRIA
Year: 2022
Reference: An Pediatr (Engl Ed). 2022 Sep;97(3):190-198. doi: 10.1016/j.anpede.2022.07.001. Epub 2022 Jul 29.
Impact factor:
Publication type: Paper in international publication
Authors: Bou-Torrent, Rosa; Galindo Zavala, Rocio; Lopez-Corbeto, Mireia; Magallares-Lopez, Berta; Martinez Regueira, Soledad; Mir-Perello, Concepcion et al.
DOI: 10.1016/j.anpede.2022.07.001

Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjogren's syndrome: an OMERACT reliability exercise.

PMID: 34849616
Journal: RHEUMATOLOGY
Year: 2022
Reference: Rheumatology (Oxford). 2022 Aug 3;61(8):3341-3350. doi: 10.1093/rheumatology/keab876.
Impact factor:
Publication type: Paper in international publication
Authors: Bruyn, George A; Chary-Valckenaere, Isabelle; Chrysidis, Stavros; Collado, Paz; D'Agostino, Maria-Antonietta; De Agustin, Juan Jose; Dejaco, Christian; Fana, Viktoria; Filippou, Gerogios; Finzel, Stephanie et al.
DOI: 10.1093/rheumatology/keab876

Exposing and Overcoming Limitations of Clinical Laboratory Tests in COVID-19 by Adding Immunological Parameters; A Retrospective Cohort Analysis and Pilot Study.

PMID: 35844497
Journal: Frontiers in Immunology
Year: 2022
Reference: Front Immunol. 2022 Jun 29;13:902837. doi: 10.3389/fimmu.2022.902837. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez, Antonio; Alvarez, Antonio; Alvarez-Sierra, Daniel; Anton, Andres; Arrese-Munoz, Iria; Bas-Minguet, Jordi; Blanco-Grau, Albert; Blanco-Grau, Albert; Bosch-Nicolau, Pau; Buzon, Maria Jose et al.
DOI: 10.3389/fimmu.2022.902837

Detailed stratified GWAS analysis for severe COVID-19 in four European populations.

PMID: 35848942
Journal: HUMAN MOLECULAR GENETICS
Year: 2022
Reference: Hum Mol Genet. 2022 Nov 28;31(23):3945-3966. doi: 10.1093/hmg/ddac158.
Impact factor:
Publication type: Paper in international publication
Authors: Acosta-Herrera, Marialbert; Afset, Jan Egil; Aghemo, Alessio; Albano, Giovanni; Albillos, Agustin; Albrecht, Wolfgang; Aliberti, Stefano; Altmuller, Janine; Ampuero, Javier; Andrade, Victor et al.
DOI: 10.1093/hmg/ddac158

Pharmacologic Treatment of Anti-MDA5 Rapidly Progressive Interstitial Lung Disease.

PMID: 34603940
Journal: Current treatment options in rheumatology
Year: 2021
Reference: Curr Treatm Opt Rheumatol. 2021;7(4):319-333. doi: 10.1007/s40674-021-00186-x. Epub 2021 Sep 28.
Impact factor:
Publication type: Review in international publication
Authors: Gil-Vila, A; Pinal-Fernandez, I; Romero-Bueno, F; Ruiz-Rodriguez, J C; Sanchez-Pernaute, O; Selva-O'Callaghan, A; Trallero-Araguas, E et al.
DOI: 10.1007/s40674-021-00186-x

Complement Component C1q as a Potential Diagnostic Tool for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Subtyping.

PMID: 34575280
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Sep 15;10(18). pii: jcm10184171. doi: 10.3390/jcm10184171.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre-Martin, Jose; Almenar-Perez, Eloy; Castro-Marrero, Jesus; Oltra, Elisa; Zacares, Mario et al.
DOI: 10.3390/jcm10184171

Effectiveness of a Multicomponent Treatment Based on Pain Neuroscience Education, Therapeutic Exercise, Cognitive Behavioral Therapy, and Mindfulness in Patients with Fibromyalgia (FIBROWALK Study): A Randomized Controlled Trial.

PMID: 34499174
Journal: Physical Therapy & Rehabilitation Journal
Year: 2021
Reference: Phys Ther. 2021 Dec 1;101(12). pii: 6362860. doi: 10.1093/ptj/pzab200.
Impact factor:
Publication type: Paper in international publication
Authors: Almirall, Miriam; Feliu-Soler, Albert; Luciano, Juan V; Mendez-Ulrich, Jorge L; Muste, Marta; Sanabria-Mazo, Juan P; Sanz, Antoni; Serrat, Mayte et al.
DOI: 10.1093/ptj/pzab200

MAX mutant small-cell lung cancers exhibit impaired activities of MGA-dependent noncanonical polycomb repressive complex.

PMID: 34493659
Journal: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Year: 2021
Reference: Proc Natl Acad Sci U S A. 2021 Sep 14;118(37). pii: 2024824118. doi: 10.1073/pnas.2024824118.
Impact factor:
Publication type: Paper in international publication
Authors: Esteller, Manel; Gomez, Antonio; Grego-Bessa, Joaquim; Javierre, Biola M; Llabata, Paula; Llinas-Arias, Pere; Romero, Octavio A; Sanchez-Cespedes, Montse; Tomas-Daza, Laureano; Torres-Diz, Manuel et al.
DOI: 10.1073/pnas.2024824118

Real-World Effectiveness of Belimumab in the Treatment of Systemic Lupus Erythematosus: Pooled Analysis of Multi-Country Data from the OBSErve Studies.

PMID: 33206344
Journal: Rheumatology and Therapy
Year: 2020
Reference: Rheumatol Ther. 2020 Dec;7(4):949-965. doi: 10.1007/s40744-020-00243-2. Epub 2020 Nov 18.
Impact factor:
Publication type: Paper in international publication
Authors: Collins, Christopher E; Cortes-Hernandez, Josefina; Gairy, Kerry; Garcia, Mercedes A; Kurtinecz, Milena; Schwarting, Andreas; Touma, Zahi; von Kempis, Johannes et al.
DOI: 10.1007/s40744-020-00243-2

Effectiveness of a Multicomponent Treatment for Fibromyalgia Based on Pain Neuroscience Education, Exercise Therapy, Psychological Support, and Nature Exposure (NAT-FM): A Pragmatic Randomized Controlled Trial.

PMID: 33081069
Journal: Journal of Clinical Medicine
Year: 2020
Reference: J Clin Med. 2020 Oct 18;9(10). pii: jcm9103348. doi: 10.3390/jcm9103348.
Impact factor:
Publication type: Paper in international publication
Authors: Almirall, Miriam; Feliu-Soler, Albert; Luciano, Juan V; Mendez-Ulrich, Jorge L; Muste, Marta; Sanabria-Mazo, Juan P; Sanz, Antoni; Serrat, Mayte et al.
DOI: 10.3390/jcm9103348

Abatacept in interstitial lung disease associated with rheumatoid arthritis: national multicenter study of 263 patients.

PMID: 33068439
Journal: RHEUMATOLOGY
Year: 2020
Reference: Rheumatology (Oxford). 2020 Dec 1;59(12):3906-3916. doi: 10.1093/rheumatology/keaa621.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera-Cros, Clara; Almodovar-Gonzalez, Raquel; Alvarez-Rivas, Maria N; Andreu, Jose L; Arboleya-Rodriguez, Luis; Bernal-Vidal, Jose A; Blanco, Ricardo; Blanco-Madrigal, Juan; Bonilla Hernan, Maria Gema; Cabezas-Rodriguez, Ivan et al.
DOI: 10.1093/rheumatology/keaa621

Cytokine profiling of extracellular vesicles isolated from plasma in myalgic encephalomyelitis/chronic fatigue syndrome: a pilot study.

PMID: 33046133
Journal: Journal of Translational Medicine
Year: 2020
Reference: J Transl Med. 2020 Oct 12;18(1):387. doi: 10.1186/s12967-020-02560-0.
Impact factor:
Publication type: Paper in international publication
Authors: Castro-Marrero, Jesus; Giloteaux, Ludovic; Hanson, Maureen R; Levine, Susan M; O'Neal, Adam et al.
DOI: 10.1186/s12967-020-02560-0

Incidence of first cardiovascular event in Spanish patients with inflammatory rheumatic diseases: prospective data from the CARMA project.

PMID: 30620291
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2019
Reference: Clin Exp Rheumatol. 2019 Sep-Oct;37(5):731-739. Epub 2019 Jan 3.
Impact factor:
Publication type: Paper in international publication
Authors: Avila Pedretti, Maria Gabriela; Babio-Herraiz, Jesus; Castaneda, Santos; Fabregas-Canales, Dolores; Garcia-Gomez, Carmen; Gonzalez-Gay, Miguel A; Gonzalez-Juanatey, Carlos; Juan-Mas, Antonio; Llorca, Javier; Lopez-Gonzalez, Ruth et al.
DOI:

Hyperlipoproteinaemia(a) in patients with spondyloarthritis: results of the Cardiovascular in Rheumatology (CARMA) project.

PMID: 30789151
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2019
Reference: Clin Exp Rheumatol. 2019 Sep-Oct;37(5):774-782. Epub 2019 Feb 15.
Impact factor:
Publication type: Paper in international publication
Authors: Avila Pedretti, Maria Gabriela; Castaneda, Santos; Erra-Duran, Alba; Fernandez-Carballido, Cristina; Fernandez-Gutierrez, Benjamin; Garcia-Arias, Miriam; Garcia-Gomez, Carmen; Garcia-Vadillo, Jesus A; Gonzalez-Fernandez, Maria J; Gonzalez-Gay, Miguel A et al.
DOI:

Urinary Neuropilin-1: A Predictive Biomarker for Renal Outcome in Lupus Nephritis.

PMID: 31533337
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2019
Reference: Int J Mol Sci. 2019 Sep 17;20(18). pii: ijms20184601. doi: 10.3390/ijms20184601.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, Josefina; Hotter, Georgina; Moline, Teresa; Ordi-Ros, Josep; Sanchis, Mireia; Sola, Anna; Sole, Cristina; Torres-Salido, Maria Teresa; Vidal, Marta; Vidal, Xavier et al.
DOI: 10.3390/ijms20184601

Biosimilar and interchangeable: Inseparable scientific concepts?

PMID: 31486117
Journal: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2019
Reference: Br J Clin Pharmacol. 2019 Nov;85(11):2460-2463. doi: 10.1111/bcp.14089. Epub 2019 Sep 4.
Impact factor:
Publication type: Paper in international publication
Authors: Abad, Miguel-Angel; Balsa, Alejandro; Carrascosa, Jose-Manuel; Cornide-Santos, Maria; de Mora, Fernando; F Duarte, Rafael; Marsal, Sara; Martinez, Rafael; P Gisbert, Javier; Wiechmann, Michael et al.
DOI: 10.1111/bcp.14089

The diagnostic work-up of cancer-associated myositis.

PMID: 29965856
Journal: CURRENT OPINION IN RHEUMATOLOGY
Year: 2018
Reference: Curr Opin Rheumatol. 2018 Nov;30(6):630-636. doi: 10.1097/BOR.0000000000000535.
Impact factor:
Publication type: Paper in international publication
Authors: Martinez-Gomez, Xavier; Pinal-Fernandez, Iago; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto et al.
DOI: 10.1097/BOR.0000000000000535

Update in ethiopathogeny, diagnosis and treatment of the IgG4 related disease.

PMID: 29241876
Journal: MEDICINA CLINICA
Year: 2018
Reference: Med Clin (Barc). 2018 Jul 13;151(1):18-25. doi: 10.1016/j.medcli.2017.10.034. Epub 2017 Dec 11.
Impact factor:
Publication type: Review in national publication
Authors: Fernandez-Codina, Andreu; Martinez-Valle, Fernando; Orozco-Galvez, Olimpia et al.
DOI: 10.1016/j.medcli.2017.10.034

Circadian rhythm abnormalities and autonomic dysfunction in patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis.

PMID: 29874259
Journal: PLoS One
Year: 2018
Reference: PLoS One. 2018 Jun 6;13(6):e0198106. doi: 10.1371/journal.pone.0198106. eCollection 2018.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Cambras, Trinitat; Castro-Marrero, Jesus; Diez-Noguera, Antoni; Zaragoza, Maria Cleofe et al.
DOI: 10.1371/journal.pone.0198106

Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus.

PMID: 29848360
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2018
Reference: Arthritis Res Ther. 2018 May 30;20(1):100. doi: 10.1186/s13075-018-1604-1.
Impact factor:
Publication type: Paper in international publication
Authors: Absher, Devin; Aguirre-Zamorano, M feminine Angeles; Andreu, Jose Luis; Blanco, Ricardo; Bonas-Guarch, Silvia; Carreira, Patricia; Corbeto, Mireia Lopez; de la Fuente, Jose Luis Marenco; Diez, Elvira; Fernandez-Nebro, Antonio et al.
DOI: 10.1186/s13075-018-1604-1

Enteric-coated mycophenolate sodium versus azathioprine in patients with active systemic lupus erythematosus: a randomised clinical trial.

PMID: 28450313
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2017
Reference: Ann Rheum Dis. 2017 Sep;76(9):1575-1582. doi: 10.1136/annrheumdis-2016-210882. Epub 2017 Apr 27.
Impact factor:
Publication type: Paper in international publication
Authors: Castro Salomo, Antoni; Cortes-Hernandez, Josefina; Cuquet Pedragosa, Jordi; Mauri Plana, Montserrat; Mitjavila, Francesca; Ordi-Ros, Josep; Ortiz-Santamaria, Vera; Perez-Conesa, Mercedes; Saez-Comet, Luis; Vidal, Xavier et al.
DOI: 10.1136/annrheumdis-2016-210882

Leveraging Molecular Data Analysis to Understand Drug Response in Systemic Sclerosis.

PMID: 28411830
Journal: JOURNAL OF INVESTIGATIVE DERMATOLOGY
Year: 2017
Reference: J Invest Dermatol. 2017 May;137(5):1000-1002. doi: 10.1016/j.jid.2017.01.009.
Impact factor:
Publication type: Paper in international publication
Authors: Julia, Antonio et al.
DOI: 10.1016/j.jid.2017.01.009

Successful treatment of constrictive chronic pericarditis with mycophenolate sodium in a patient with systemic sclerosis.

PMID: 28283274
Journal: MEDICINA CLINICA
Year: 2017
Reference: Med Clin (Barc). 2017 Jun 21;148(12):574-575. doi: 10.1016/j.medcli.2017.01.027. Epub 2017 Mar 7.
Impact factor:
Publication type: Paper in national publication
Authors: Fernandez-Codina, Andreu; Fonollosa-Pla, Vicent; Francisco-Pascual, Jaume et al.
DOI: 10.1016/j.medcli.2017.01.027

Autoantibodies to types I and IV collagen and heart valve disease in systemic lupus erythematosus/antiphospholipid syndrome.

PMID: 28283766
Journal: CLINICAL RHEUMATOLOGY
Year: 2017
Reference: Clin Rheumatol. 2017 Jun;36(6):1401-1406. doi: 10.1007/s10067-017-3594-9. Epub 2017 Mar 10.
Impact factor:
Publication type: Paper in international publication
Authors: Balada, Eva; Castro-Marrero, Jesus; Cortes-Hernandez, Josefina; Ordi-Ros, Jose; Pardos-Gea, Jose et al.
DOI: 10.1007/s10067-017-3594-9

Genome-Wide Association Study Identifies IRX1 as a Risk Locus for Rheumatoid Factor Positivity in Rheumatoid Arthritis.

PMID: 26815016
Journal: Ophthalmic Surgery Lasers & Imaging Retina
Year: 2016
Reference: Arthritis Rheumatol. 2016 Jun;68(6):1384-91. doi: 10.1002/art.39591.
Impact factor:
Publication type: Paper in international publication
Authors: Absher, Devin; Alonso, Arnald; Alperi-Lopez, Mercedes; Bertranpetit, Jaume; Blanco, Francisco; Canete, Juan D; Codo, Laia; Corominas, Hector; Erra, Alba; Fernandez-Gutierrez, Benjamin et al.
DOI: 10.1002/art.39591

Pharmacogenomics of anti-TNF response in psoriasis, where are we?

PMID: 26871199
Journal: PHARMACOGENOMICS
Year: 2016
Reference: Pharmacogenomics. 2016 Mar;17(4):323-6. doi: 10.2217/pgs.15.168. Epub 2016 Feb 12.
Impact factor:
Publication type: Review in international publication
Authors: Julia, Antonio; Marsal, Sara et al.
DOI:

Comprehensive description of clinical characteristics of a large systemic lupus erythematosus cohort from the Spanish Rheumatology Society Lupus Registry (RELESSER) with emphasis on complete versus incomplete lupus differences.

PMID: 25569641
Journal: MEDICINE
Year: 2015
Reference: Medicine (Baltimore). 2015 Jan;94(1):e267. doi: 10.1097/MD.0000000000000267.
Impact factor:
Publication type: Paper in international publication
Authors: Aguirre, Angeles; Alegre, Juan; Blanco, Ricardo; Bonilla, Gema; Calvo-Alen, Jaime; Carreira, Patricia; Castellvi, Ivan; de Castro, Monica Fernandez; de la Pena, Paloma Garcia; Diez-Alvarez, Elvira et al.
DOI: 10.1097/MD.0000000000000267

Identification of risk loci for Crohn's disease phenotypes using a genome-wide association study.

PMID: 25557950
Journal: GASTROENTEROLOGY
Year: 2015
Reference: Gastroenterology. 2015 Apr;148(4):794-805. doi: 10.1053/j.gastro.2014.12.030. Epub 2014 Dec 31.
Impact factor:
Publication type: Paper in international publication
Authors: Absher, Devin; Alonso, Arnald; Andreu, Montserrat; Barreiro-de Acosta, Manuel; Bertranpetit, Jaume; Cabre, Eduard; Chaparro, Maria; Domenech, Eugeni; Esteve, Maria; Garcia-Montero, Andres C et al.
DOI: 10.1053/j.gastro.2014.12.030

Etanercept in refractory lupus arthritis: An observational study.

PMID: 25712812
Journal: SEMIN ARTHRITIS RHEU
Year: 2015
Reference: Semin Arthritis Rheum. 2015 Jun;44(6):672-9. doi: 10.1016/j.semarthrit.2015.01.006. Epub 2015 Jan 23.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, Josefina; Egri, Natalia; Ordi-Ros, Josep; Vilardell-Tarres, Miquel et al.
DOI: 10.1016/j.semarthrit.2015.01.006

Comorbid personality disorders in chronic fatigue syndrome patients: a marker of psychopathological severity.

PMID: 25812543
Journal: ACTAS ESP PSIQUIATRI
Year: 2015
Reference: Actas Esp Psiquiatr. 2015 Mar-Apr;43(2):58-65. Epub 2015 Mar 1.
Impact factor:
Publication type: Paper in national publication
Authors: Alegre, Jose; Calvo, Natalia; Casas, Miguel; Saez-Francas, Naia; Valero, Sergi et al.
DOI:

Good outcome of interstitial lung disease in patients with scleroderma associated to anti-PM/Scl antibody.

PMID: 25110305
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2014
Reference: Semin Arthritis Rheum. 2014 Dec;44(3):331-7. doi: 10.1016/j.semarthrit.2014.07.002. Epub 2014 Jul 15.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Vila, Serafin; Fernandez-Codina, Andreu; Fonollosa-Pla, Vicent; Guillen-Del Castillo, Alfredo; Munoz, Xavier; Pallisa, Esther; Pilar Simeon-Aznar, Carmen; Reverte-Vinaixa, Maria M; Selva-OCallaghan, Albert; Vilardell-Tarres, Miquel et al.
DOI: 10.1016/j.semarthrit.2014.07.002

Neutrophil gelatinase-associated lipocalin as a biomarker for lupus nephritis.

PMID: 24711435
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2014
Reference: Nephrol Dial Transplant. 2014 Sep;29(9):1740-9. doi: 10.1093/ndt/gfu062. Epub 2014 Apr 7.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, Josefina; Ordi-Ros, Josep; Pedrosa Anna; Torres-Salido, Maria Teresa; Vidal, Xavier; Vilardell-Tarres, Miquel et al.
DOI: 10.1093/ndt/gfu062

Rheumatology assistance care in Catalonia (Spain): Year 2012.

PMID: 24252627
Journal: Reumatología clinica
Year: 2014
Reference: Reumatol Clin. 2014 Mar-Apr;10(2):85-8. doi: 10.1016/j.reuma.2013.05.012. Epub 2013 Nov 17.
Impact factor:
Publication type: Letter or abstract
Authors: Grados, Dolors; Marsal, Sara; Olive, Alejandro et al.
DOI: 10.1016/j.reuma.2013.05.012

Chronic fatigue syndrome and personality: A case-control study using the alternative five factor model.

PMID: 24630915
Journal: PSYCHIATRY RESEARCH
Year: 2014
Reference: Psychiatry Res. 2014 May 30;216(3):373-8. doi: 10.1016/j.psychres.2014.02.031. Epub 2014 Mar 3.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Calvo, Natalia; Casas, Miquel; de Sevilla, Tomas Fernandez; Goma-I-Freixanet, Montserrat; Saez-Francas, Naia; Valero, Sergi et al.
DOI: 10.1016/j.psychres.2014.02.031

Could mitochondrial dysfunction be a differentiating marker between Chronic Fatigue Syndrome and Fibromyalgia?

PMID: 23600892
Journal: ANTIOXIDANTS & REDOX SIGNALING
Year: 2013
Reference: Antioxid Redox Signal. 2013 Nov 20;19(15):1855-60. doi: 10.1089/ars.2013.5346. Epub 2013 May 29.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar-Montilla, Francisco J; Alegre-Martin, Jose; Aliste, Luisa; Castro-Marrero, Jesus; Cordero, Mario D; Jimenez-Gutierrez, Conxita; Saez-Francas, Naia et al.
DOI: 10.1089/ars.2013.5346

Calcineurin inhibitors in a cohort of patients with antisynthetase-associated interstitial lung disease.

PMID: 23465087
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2013
Reference: Clin Exp Rheumatol. 2013 May-Jun;31(3):436-9. Epub 2013 Mar 7.
Impact factor:
Publication type: Paper in international publication
Authors: Labirua-Iturburu, Ane; Labrador-Horrillo, Moises; Martinez-Gomez, Xavier; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto; Vilardell-Tarres, Miquel et al.
DOI:

[Absence of xenotropic murine leukaemia virus-related virus sequences in healthy blood donors and chronic fatigue syndrome patients in Catalonia, Spain.]

PMID: 23332972
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2013
Reference: Enferm Infecc Microbiol Clin. 2013 Aug-Sep;31(7):491-2. doi: 10.1016/j.eimc.2012.11.016. Epub 2013 Jan 17.
Impact factor:
Publication type: Letter whit IF
Authors: Alegre, Jose; Piron, Maria; Ribera, Esteban; Sauleda, Silvia et al.
DOI: 10.1016/j.eimc.2012.11.016

Three-dimensional Volumetric Ultrasound: A Valid Method for Blinded Assessment of Response to Therapy in Rheumatoid Arthritis.

PMID: 23322469
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2013
Reference: J Rheumatol. 2013 Mar;40(3):253-60. doi: 10.3899/jrheum.121103. Epub 2013 Jan 15.
Impact factor:
Publication type: Paper in international publication
Authors: Acebes, Carlos; Brito, Elia; de Agustin, Juan Jose; de Miguel, Eugenio; Garrido, Jesus; Martinez-Hernandez, David; Mayordomo, Lucia; Moller, Ingrid; Moragues, Carmen; Naredo, Esperanza et al.
DOI: 10.3899/jrheum.121103

Usefulness of anti-p155 autoantibody for diagnosing cancer-associated dermatomyositis: A systematic review and meta-analysis.

PMID: 21953614
Journal: ARTHRITIS AND RHEUMATISM
Year: 2012
Reference: Arthritis Rheum. 2012 Feb;64(2):523-32. doi: 10.1002/art.33379.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; et al.
DOI: 10.1002/art.33379

Psycho-physiological impact on women with chronic fatigue syndrome in the context of their couple relationship.

PMID: 21745025
Journal: Psychology Health & Medicine
Year: 2012
Reference: Psychol Health Med. 2012 Mar;17(2):150-63. Epub 2011 Jul 11.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; et al.
DOI: 10.1080/13548506.2011.582124

Anti-TIF1gamma antibodies (anti-p155) in adult patients with dermatomyositis: comparison of different diagnostic assays.

PMID: 22294626
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2012
Reference: Ann Rheum Dis. 2012 Jun;71(6):993-6. doi: 10.1136/annrheumdis-2011-200871. Epub 2012 Jan 30.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1136/annrheumdis-2011-200871

Central nervous system gene expression changes in a transgenic mouse model for bovine spongiform encephalopathy.

PMID: 22035425
Journal: VETERINARY RESEARCH
Year: 2011
Reference: Vet Res. 2011 Oct 28;42(1):109. doi: 10.1186/1297-9716-42-109.
Impact factor:
Publication type: Paper in international publication
Authors: Arino, Joaquin; Barcelo, Anna; Castells, Xavier; Costa, Carme; Pumarola, Marti; Ruiz de Villa, Maria del Carmen; Sanchez, Alex; Torres, Juan Maria; Tortosa, Raul; Vidal, Enric et al.
DOI: 10.1186/1297-9716-42-109

Deletion of the late cornified envelope genes, LCE3C and LCE3B, is associated with rheumatoid arthritis.

PMID: 20213803
Journal: ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
Year: 2010
Reference: Arthritis Rheum. 2010 May;62(5):1246-51.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1002/art.27381

Echocardiography at diagnosis of antiphospholipid syndrome provides prognostic information on valvular disease evolution and identifies two subtypes of patients.

PMID: 20068017
Journal: LUPUS
Year: 2010
Reference: Lupus. 2010;19(5):575-82. Epub 2010 Jan 12.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1177/0961203309353772

Cancer-associated myositis and anti-p155 autoantibody in a series of 85 patients with idiopathic inflammatory myopathy.

PMID: 20075704
Journal: MEDICINE
Year: 2010
Reference: Medicine (Baltimore). 2010 Jan;89(1):47-52.
Impact factor:
Publication type: Paper in international publication
Authors: Labrador-Horrillo, Moises; Martinez, Maria Angeles; Martinez-Gomez, Xavier; Palou, Eduard; Rodriguez-Sanchez, Jose Luis; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto; Vilardell-Tarres, Miquel et al.
DOI: 10.1097/MD.0b013e3181ca14ff

An eight-gene blood expression profile predicts the response to infliximab in rheumatoid arthritis.

PMID: 19847310
Journal: PLoS One
Year: 2009
Reference: PLoS One. 2009 Oct 22;4(10):e7556.
Impact factor:
Publication type: Letter or abstract
Authors: Barcelo, Pere; Erra, Alba; Julia, Antonio; Marsal, Sara; Palacio, Carles; Sans, Xavier; Tomas, Carlos et al.
DOI: 10.1371/journal.pone.0007556

Identification of candidate genes for rituximab response in rheumatoid arthritis patients by microarray expression profiling in blood cells.

PMID: 19842941
Journal: PHARMACOGENOMICS
Year: 2009
Reference: Pharmacogenomics. 2009 Oct;10(10):1697-708.
Impact factor:
Publication type: Paper in international publication
Authors: Barcelo, Mireia; Erra, Alba; Julia, Antonio; Marsal, Sara; Palacio, Carles et al.
DOI: 10.2217/pgs.09.99

Genetic risk factors of thrombosis in the antiphospholipid syndrome.

PMID: 19659549
Journal: BRITISH JOURNAL OF HAEMATOLOGY
Year: 2009
Reference: Br J Haematol. 2009 Nov;147(3):289-96.
Impact factor:
Publication type: Review in international publication
Authors: ; ; ; et al.
DOI: 10.1111/j.1365-2141.2009.07831.x

DAS-28-based EULAR response and HAQ improvement in rheumatoid arthritis patients switching between TNF antagonists.

PMID: 19627609
Journal: BMC MUSCULOSKELETAL DISORDERS
Year: 2009
Reference: BMC Musculoskelet Disord. 2009 Jul 23;10:91.
Impact factor:
Publication type: Paper in international publication
Authors: Barcelo, Mireia; Gomez-Reino, Juan J; Hernandez, Blanca; Marsal, Sara; Navarro-Compan, Victoria; Navarro-Sarabia, Federico; Perez-Pampin, Eva; Ruiz-Montesinos, Dolores et al.
DOI: 10.1186/1471-2474-10-91

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Funded by the European Union, this project coordinated by the Vall d'Hebron Research Institute (VHIR) seeks to develop more effective therapies by creating new combinations of existing drugs

The head of the Rheumatology Service at Vall d'Hebron University Hospital and of the Rheumatology research group at VHIR is a highly accomplished rheumatologist with a distinguished career in the field.

It is the first international multi-centre clinical trial to analyse the safety and effect of this treatment for an autoimmune disease.