About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Rheumatology Research Group (GRR) is focused on translational research in immunity-mediated inflammatory diseases (IMIDA), mainly in the area of rheumatology. The GRR is a multidisciplinary group made up of clinical specialists, biologists, bioinformaticians and laboratory technicians. The different research lines of the GRR emphasize the use of high-performance technologies for the study at the cellular and molecular level of the immununopathology of IMIDA, mainly chronic inflammatory arthritis and autoimmune systemic diseases.
At the clinical level, we have developed lines of research in very diverse areas of rheumatology, including chronic inflammatory arthritis (rheumatoid arthritis, spondyloarthropathies), systemic autoimmune diseases (lupus, myositis, Sjögren's syndrome), the study of musculoskeletal imaging, pediatric rheumatology (juvenile idiopathic arthritis, autoimmune systemic diseases, autoinflammatory syndromes), central sensitization syndromes and the study of bone metabolism. One of the main objectives of the GRR is the coordination of basic and clinical research to accelerate the transfer of knowledge to clinical practice and thus improve the quality of life of patients.
PMID: 37884354 Journal: GUT Year: 2023 Reference: Gut. 2023 Oct 26:gutjnl-2023-329923. doi: 10.1136/gutjnl-2023-329923. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan G; Agueras, Cajal; Agueras, Cajal; Alessandria, Carlo; Allegretti, Andrew S; Alonso, Sonia; Asrani, Sumeet K; Beuers, Ulrich; Campion, Daniela; Caraceni, Paolo et al. DOI: 10.1136/gutjnl-2023-329923
PMID: 37893239 Journal: Biomedicines Year: 2023 Reference: Biomedicines. 2023 Oct 23;11(10):2867. doi: 10.3390/biomedicines11102867. Impact factor: Publication type: Paper in international publication Authors: Aban, M; Abraldes, Juan G; Alegre-Martin, Jose; Alessandria, Carlo; Allegretti, Andrew S; Alonso, Sonia; Andrade, R; Angeli, P; Asrani, Sumeet K; Avitabile, E et al. DOI: 10.3390/biomedicines11102867
PMID: 37935561 Journal: Year: 2023 Reference: Open Heart. 2023 Nov;10(2):e002431. doi: 10.1136/openhrt-2023-002431. Impact factor: Publication type: Paper in international publication Authors: Aguade-Bruix, Santiago; Aterido, A; Carrascosa-Carrillo, J M; Ferreira Gonzalez, Ignacio; Guillen, Y; Julia, A; Li, T; Marsal, S; Martinez, S; Romero-Farina, Guillermo et al. DOI: 10.1136/openhrt-2023-002431
PMID: 37960157 Journal: Nutrients Year: 2023 Reference: Nutrients. 2023 Oct 24;15(21):4504. doi: 10.3390/nu15214504. Impact factor: Publication type: Paper in international publication Authors: Alegre-Martin, Jose; Awad, Mark M; Castro-Marrero, Jesus; Cheema, Parneet K; Csoszi, Tibor; Gottfried, Maya; Gumus, Mahmut; Jurek, Joanna; Kalemkerian, Gregory P; Kato, Terufumi et al. DOI: 10.3390/nu15214504
PMID: 35396580 Journal: NATURE Year: 2022 Reference: Nature. 2022 Apr;604(7906):502-508. doi: 10.1038/s41586-022-04434-5. Epub 2022 Apr 8. Impact factor: Publication type: Paper in international publication Authors: Abyzov, Alexej; Achsel, Tilmann; Adams, Mark; Adolfsson, Rolf; Agartz, Ingrid; Agerbo, Esben; Agiananda, Feranindhya; Akbarian, Schahram; Al Eissa, Mariam; Albus, Margot et al. DOI: 10.1038/s41586-022-04434-5
PMID: 35377229 Journal: Microbiology Spectrum Year: 2022 Reference: Microbiol Spectr. 2022 Apr 27;10(2):e0214921. doi: 10.1128/spectrum.02149-21. Epub 2022 Apr 4. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Casillas, Rosario; Cortese, Maria Francesca; Esteban, Rafael; Ferrer-Costa, Roser; Garcia-Garcia, Selene; Kuchta, Alison; Pacin, Beatriz; Palom, Adriana; Pumarola, Tomas et al. DOI: 10.1128/spectrum.02149-21
PMID: 35349419 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2022 Reference: Clin Exp Rheumatol. 2022 May;40 Suppl 134(5):3-11. doi: 10.55563/clinexprheumatol/d2qz38. Epub 2022 Mar 29. Impact factor: Publication type: Review in international publication Authors: Aguilera, Silvia; Alexander, Tobias; Amoura, Zahir; Andersen, Janette; Arnaud, Laurent; Avcin, Tadej; Beretta, Lorenzo; Bombardieri, Stefano; Bortoluzzi, Alessandra; Bouillot, Coralie et al. DOI:
PMID: 35293988 Journal: RHEUMATOLOGY Year: 2022 Reference: Rheumatology (Oxford). 2022 Nov 28;61(12):4863-4874. doi: 10.1093/rheumatology/keac162. Impact factor: Publication type: Paper in international publication Authors: Airoldi, Carla; Aydin, Sibel Zehra; Becciolini, Andrea; Bonfiglioli, Karina; Bruns, Alessandra; Carrara, Greta; Cazenave, Tomas; Ciapetti, Alessandro; Cipolletta, Edoardo; Cosatti, Micaela Ana et al. DOI: 10.1093/rheumatology/keac162
PMID: 34075090 Journal: Scientific Reports Year: 2021 Reference: Sci Rep. 2021 Jun 1;11(1):11462. doi: 10.1038/s41598-021-90797-0. Impact factor: Publication type: Paper in international publication Authors: Bonafonte-Pardas, Irene; Gomez, Antonio; Julia, Antonio; Llados, Jordi; Lopez-Corbeto, Mireia; Lopez-Lasanta, Maria; Marsal, Sara; Martinez-Mateu, Sergio H; Myers, Richard M; Rodriguez-Nunez, Ivan et al. DOI: 10.1038/s41598-021-90797-0
PMID: 33996816 Journal: Frontiers in Cell and Developmental Biology Year: 2021 Reference: Front Cell Dev Biol. 2021 Apr 29;9:655201. doi: 10.3389/fcell.2021.655201. eCollection 2021. Impact factor: Publication type: Paper in international publication Authors: Aranda, Sergi; Ballare, Cecilia; Blanco, Enrique; Di Croce, Luciano; Garcia-Montolio, Marc; Gomez, Antonio; Gutierrez, Arantxa; Hughes, Timothy P; Kok, Chung H; Vizan, Pedro et al. DOI: 10.3389/fcell.2021.655201
PMID: 33301929 Journal: JOINT BONE SPINE Year: 2021 Reference: Joint Bone Spine. 2021 May;88(3):105115. doi: 10.1016/j.jbspin.2020.105115. Epub 2020 Dec 7. Impact factor: Publication type: Paper in international publication Authors: Atienza-Mateo, Belen; Bonilla, Gema; Calvo-Alen, Jaime; Castaneda, Santos; Cavagna, Lorenzo; Cifrian, Jose M; Cuesta, Victor M Mora; Diez, Elvira; Fernandez, David Iturbe; Genre, Fernanda et al. DOI: 10.1016/j.jbspin.2020.105115
PMID: 33004539 Journal: JOURNAL OF RHEUMATOLOGY Year: 2021 Reference: J Rheumatol. 2021 May;48(5):741-750. doi: 10.3899/jrheum.200300. Epub 2020 Oct 1. Impact factor: Publication type: Paper in international publication Authors: Adan, Alfredo; Alvarez, Enrique Raya; Atienza-Mateo, Belen; Aurrecoechea, Elena; Beltran, Emma; Blanco, Ricardo; Calvo-Rio, Vanesa; Caracuel, Miguel A; Castaneda, Santos; Demetrio-Pablo, Rosalia et al. DOI: 10.3899/jrheum.200300
PMID: 32432991 Journal: International Journal of Qualitative Studies on Health and Well-Being Year: 2020 Reference: Int J Qual Stud Health Well-being. 2020 Dec;15(1):1764830. doi: 10.1080/17482631.2020.1764830. Impact factor: Publication type: Paper in international publication Authors: Bolle Strand, Elin; Castro-Marrero, Jesus; Helland, Ingrid Bergliot; Meeus, Mira; Mengshoel, Anne Marit; Pheby, Derek et al. DOI: 10.1080/17482631.2020.1764830
PMID: 32424615 Journal: RHEUMATOLOGY INTERNATIONAL Year: 2020 Reference: Rheumatol Int. 2020 Sep;40(9):1473-1480. doi: 10.1007/s00296-020-04598-1. Epub 2020 May 18. Impact factor: Publication type: Paper in international publication Authors: Forger, Frauke; Julia, Antonio; Marsal, Sara; Micu, Mihaela C; Ostensen, Monika; Pluma, Andrea et al. DOI: 10.1007/s00296-020-04598-1
PMID: 32425260 Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM Year: 2020 Reference: Semin Arthritis Rheum. 2020 May 16. doi: 10.1016/j.semarthrit.2020.05.001. Impact factor: Publication type: Paper in international publication Authors: Añez, Gustavo Adolfo; Almirall, Miriam; Antón, Susana; Barceló-Bru, Mireia; Borrell, Helena; Caparrós-Ruiz, Raquel; De AgustÃn, Juan José; Erra, Alba; Espartal, Esther; Julià , Antonio et al. DOI: 10.1016/j.semarthrit.2020.05.001
PMID: 32393363 Journal: GENOME BIOLOGY Year: 2020 Reference: Genome Biol. 2020 May 11;21(1):112. doi: 10.1186/s13059-020-02032-0. Impact factor: Publication type: Paper in international publication Authors: Aymerich, Marta; Ballestar, Esteban; Campo, Elias; Colomer, Dolors; Heyn, Holger; Iacono, Giovanni; Julia, Antonio; Kulis, Marta; Marchese, Domenica; Marsal, Sara et al. DOI: 10.1186/s13059-020-02032-0
PMID: 31043678 Journal: PHARMACOGENOMICS JOURNAL Year: 2019 Reference: Pharmacogenomics J. 2019 Dec;19(6):547-555. doi: 10.1038/s41397-019-0090-4. Epub 2019 May 2. Impact factor: Publication type: Paper in international publication Authors: Andreu, Montserrat; Aterido, Adria; Barreiro-de Acosta, Manuel; Chaparro, Maria; Codo, Laia; Domenech, Eugeni; Esteve, Maria; Garcia-Montero, Andres; Garcia-Planella, Esther; Garcia-Sanchez, Valle et al. DOI: 10.1038/s41397-019-0090-4
PMID: 31036626 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2019 Reference: Ann Rheum Dis. 2019 Jul;78(7):967-973. doi: 10.1136/annrheumdis-2019-215024. Epub 2019 Apr 29. Impact factor: Publication type: Paper in international publication Authors: Alavi, Zarrin; Backhaus, Marina; Bruyn, G A W; Chary-Valckenaere, Isabelle; Chrysidis, Stavros; Collado, Paz; D'Agostino, Maria Antonietta; de Agustin, Juan Jose; Dejaco, Christian; El Mardenly, Ghada et al. DOI: 10.1136/annrheumdis-2019-215024
PMID: 31004236 Journal: Metabolomics Year: 2019 Reference: Metabolomics. 2019 Apr 19;15(4):65. doi: 10.1007/s11306-019-1527-0. Impact factor: Publication type: Paper in international publication Authors: Armando, Aaron M; Boyd, Tristan; Coras, Roxana; Dahlberg-Wright, Signe; Guma, Monica; Huynh, Quyen; Jain, Mohit; Kavanaugh, Arthur; Marsal, Sara; Paravar, Taraneh et al. DOI: 10.1007/s11306-019-1527-0
PMID: 30952369 Journal: GYNECOLOGIC ONCOLOGY Year: 2019 Reference: Gynecol Oncol. 2019 Jun;153(3):549-554. doi: 10.1016/j.ygyno.2019.03.241. Epub 2019 Apr 3. Impact factor: Publication type: Paper in international publication Authors: Cascales-Campos, P A; Chiantera, V; Di Donna, M C; Domingo, S; Fornes, V; Fotopoulou, C; Garcia-Granero, A; Gil-Moreno, A; Jurado, M; Lago, V et al. DOI: 10.1016/j.ygyno.2019.03.241
PMID: 29314762 Journal: International Journal of Rheumatic Diseases Year: 2018 Reference: Int J Rheum Dis. 2018 Feb;21(2):487-496. doi: 10.1111/1756-185X.13255. Epub 2018 Jan 5. Impact factor: Publication type: Paper in international publication Authors: Curran, Adrian; Fernandez-Codina, Andreu; Pinal-Fernandez, Iago; Redondo-Benito, Ada; Rodrigo-Pendas, Jose Angel; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto; Villar-Gomez, Ana et al. DOI: 10.1111/1756-185X.13255
PMID: 28249725 Journal: JOINT BONE SPINE Year: 2018 Reference: Joint Bone Spine. 2018 Jan;85(1):119. doi: 10.1016/j.jbspin.2017.02.008. Epub 2017 Feb 27. Impact factor: Publication type: Paper in international publication Authors: Fernandez-Codina, Andreu; Martinez-Valle, Fernando; Simo, Marc; Solans-Laque, Roser et al. DOI: 10.1016/j.jbspin.2017.02.008
Funded by the European Union, this project coordinated by the Vall d'Hebron Research Institute (VHIR) seeks to develop more effective therapies by creating new combinations of existing drugs
The head of the Rheumatology Service at Vall d'Hebron University Hospital and of the Rheumatology research group at VHIR is a highly accomplished rheumatologist with a distinguished career in the field.
It is the first international multi-centre clinical trial to analyse the safety and effect of this treatment for an autoimmune disease.
