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Spine Research Unit

The Vall d’Hebron Spine Research Unit (VHSRU) is a growing multidisciplinary group of professionals devoted to spinal disorders with an increasing impact in terms of number of publications, associated IF and research funding. VHSRU has published 198 articles in spine field, 40% of them Q1, with a total IF of 451,9. 

Our research unit is organized in four research lines: 

  • Pediatric and adolescent deformity, 
  • Adult deformity, 
  • Spinal cord injuries,
  • Cellular therapy and new surgical techniques.

VHRSU has been involved as coordinator or collaborator in 25 funded research projects. VHRSU is currently coordinating 5 competitive projects granted by national and international institutions (Marató TV3, Eurospine, SRS, AO, GEER). One of our research projects, the European Spine Study Group (ESSG), has been very successful, with more than 60 published manuscripts and 244 podium presentations. All these projects allowed us to establish new synergies with other research centers and universities. We hope to expand this network in the future. 

Publications

Ideal sagittal profile restoration and ideal lumbar apex positioning play an important role in postoperative mechanical complications after a lumbar PSO.

PMID: 31925761
Journal: Spine deformity
Year: 2020
Reference: Spine Deform. 2020 Jun;8(3):491-498. doi: 10.1007/s43390-019-00005-3. Epub 2020 Jan 8.
Impact factor: 0
Publication type: Paper in international publication
Authors: Pizones, Javier, Perez-Grueso, Francisco Javier Sanchez, Moreno-Manzanaro, Lucia, Vila-Casademunt, Alba, Boissiere, Louis, Yilgor, Caglar, Fernandez-Baillo, Nicomedes, Sanchez-Marquez, Jose Miguel, Talavera, Gloria, Acaroglu, Emre R et al.
DOI: 10.1007/s43390-019-00005-3

The Effect of Tobacco Smoking on Adverse Events Following Adult Complex Deformity Surgery: Analysis of 270 Patients from The Prospective, Multi-center Scoli-RISK-1 study.

PMID: 31415459
Journal: SPINE
Year: 2020
Reference: Spine (Phila Pa 1976). 2020 Jan 1;45(1):32-37. doi: 10.1097/BRS.0000000000003200.
Impact factor: 2.646
Publication type: Paper in international publication
Authors: Wilson, Jamie R F, Jiang, Fan, Badhiwala, Jetan H, Shaffrey, Christopher L, Carreon, Leah Y, Cheung, Kenneth M C, Dahl, Benny T, Ames, Christopher P, Boachie-Adjei, Oheneba, Dekutoski, Mark B et al.
DOI: 10.1097/BRS.0000000000003200

Acute spinal implant infection treated with debridement: does extended antibiotic treatment improve the prognosis?

PMID: 30904996
Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Year: 2019
Reference: Eur J Clin Microbiol Infect Dis. 2019 May;38(5):951-958. doi: 10.1007/s10096-019-03537-8. Epub 2019 Mar 23.
Impact factor: 2.591
Publication type: Paper in international publication
Authors: Bosch-Nicolau, Pau, Rodriguez-Pardo, Dolors, Pigrau, Carles, Pellise, Ferran, Haddad, Sleiman, Lung, Mayli, Almirante, Benito et al.
DOI: 10.1007/s10096-019-03537-8

Development of Deployable Predictive Models for Minimal Clinically Important Difference Achievement Across the Commonly Used Health-Related Quality of Life Instruments in Adult Spinal Deformity Surgery.

PMID: 30896589
Journal: SPINE
Year: 2019
Reference: Spine (Phila Pa 1976). 2019 Aug 15;44(16):1144-1153. doi: 10.1097/BRS.0000000000003031.
Impact factor: 2.903
Publication type: Paper in international publication
Authors: Ames, Christopher P, Smith, Justin S, Pellise, Ferran, Kelly, Michael P, Gum, Jeffrey L, Alanay, Ahmet, Acaroglu, Emre, Perez-Grueso, Francisco Javier Sanchez, Kleinstuck, Frank S, Obeid, Ibrahim et al.
DOI: 10.1097/BRS.0000000000003031

Adult spinal deformity surgical decision-making score : Part 1: development and validation of a scoring system to guide the selection of treatment modalities for patients below 40 years with adult spinal deformity.

PMID: 30847705
Journal: EUROPEAN SPINE JOURNAL
Year: 2019
Reference: Eur Spine J. 2019 Jul;28(7):1652-1660. doi: 10.1007/s00586-019-05932-3. Epub 2019 Mar 7.
Impact factor: 2.513
Publication type: Paper in international publication
Authors: Vital, Jean-Marc, Fujishiro, Takashi, Boissiere, Louis, Cawley, Derek Thomas, Larrieu, Daniel, Gille, Olivier, Kleinstuck, Frank, Acaroglu, Emre, Alanay, Ahmet, Obeid, Ibrahim et al.
DOI: 10.1007/s00586-019-05932-3

30-Day unplanned surgery in cervical spondylotic myelopathy surgically treated: a single-center experience.

PMID: 30798453
Journal: EUROPEAN SPINE JOURNAL
Year: 2019
Reference: Eur Spine J. 2019 May;28(5):1209-1216. doi: 10.1007/s00586-019-05892-8. Epub 2019 Feb 23.
Impact factor: 2.513
Publication type: Paper in international publication
Authors: Plano, Xavier, Ramirez, Manuel, Matamalas, Antonia, Haddad, Sleiman, Garcia de Frutos, Ana, Casamitjana, J M, Pellise, Ferran et al.
DOI: 10.1007/s00586-019-05892-8

Sagittal radiographic parameters demonstrate weak correlations with pretreatment patient-reported health-related quality of life measures in symptomatic de novo degenerative lumbar scoliosis: a European multicenter analysis.

PMID: 29570046
Journal: JOURNAL OF NEUROSURGERY-SPINE
Year: 2018
Reference: J Neurosurg Spine. 2018 Jun;28(6):573-580. doi: 10.3171/2017.8.SPINE161266. Epub 2018 Mar 23.
Impact factor: 2.761
Publication type: Paper in international publication
Authors: Holewijn, Roderick M, Faraj, Sayf S A, De Kleuver, Marinus, Vila-Casademunt, Alba, Alanay, Ahmet, Kleinstuck, Frank, Perez-Grueso, Francisco S, Pellise, Ferran, Acaroglu, Emre, Obeid, Ibrahim et al.
DOI: 10.3171/2017.8.SPINE161266

NRS20: Combined Back and Leg Pain Score: A simple and Effective Assessment of Adult Spinal Deformity.

PMID: 29529002
Journal: SPINE
Year: 2018
Reference: Spine (Phila Pa 1976). 2018 Sep 1;43(17):1184-1192. doi: 10.1097/BRS.0000000000002633.
Impact factor: 2.792
Publication type: Paper in international publication
Authors: Cawley, Derek T, Larrieu, Daniel, Fujishiro, Takashi, Kieser, David, Bossiere, Louis, Acaroglu, Emre, Alanay, Ahmet, Kleinsteuck, Frank, Pellise, Ferran, Perez-Grueso, Francisco Sanchez et al.
DOI: 10.1097/BRS.0000000000002633

Relative pelvic version (RPV): an individualized pelvic incidence-based proportional parameter that quantifies pelvic version more precisely than pelvic tilt.

PMID: 29526641
Journal: Spine Journal
Year: 2018
Reference: Spine J. 2018 Oct;18(10):1787-1797. doi: 10.1016/j.spinee.2018.03.001. Epub 2018 Mar 8.
Impact factor: 3.119
Publication type: Paper in international publication
Authors: Yilgor, Caglar, Yavuz, Yasemin, Sogunmez, Nuray, Haddad, Sleiman, Mannion, Anne F, Abul, Kadir, Boissiere, Louis, Obeid, Ibrahim, Kleinstuck, Frank, Perez-Grueso, Francisco Javier Sanchez et al.
DOI: 10.1016/j.spinee.2018.03.001

Factor analysis of the SRS-22 outcome assessment instrument in patients with adult spinal deformity.

PMID: 28866740
Journal: EUROPEAN SPINE JOURNAL
Year: 2018
Reference: Eur Spine J. 2018 Mar;27(3):685-699. doi: 10.1007/s00586-017-5279-0. Epub 2017 Sep 2.
Impact factor: 2.634
Publication type: Paper in international publication
Authors: Mannion, A F, Elfering, A, Bago, J, Pellise, F, Vila-Casademunt, A, Richner-Wunderlin, S, Domingo-Sabat, M, Obeid, I, Acaroglu, E, Alanay, A et al.
DOI: 10.1007/s00586-017-5279-0

Thoracic wall reconstruction with bioabsorbable plates in pediatric malignant thoracic wall tumors.

PMID: 27653461
Journal: JOURNAL OF PEDIATRIC SURGERY
Year: 2017
Reference: J Pediatr Surg. 2017 Mar;52(3):377-381. doi: 10.1016/j.jpedsurg.2016.08.018. Epub 2016 Aug 31.
Impact factor: 1.976
Publication type: Paper in international publication
Authors: Guillen, G, Garcia, L, Marhuenda, C, Pellise, F, Molino, J A, Fontecha, C G, Lopez, S, Lloret, J et al.
DOI: 10.1016/j.jpedsurg.2016.08.018

Intraoperative tranexamic acid use in major spine surgery in adults: a multicentre, randomized, placebo-controlled trialdagger.

PMID: 28203735
Journal: BRITISH JOURNAL OF ANAESTHESIA
Year: 2017
Reference: Br J Anaesth. 2017 Mar 1;118(3):380-390. doi: 10.1093/bja/aew434.
Impact factor: 6.238
Publication type: Paper in international publication
Authors: Colomina, M J, Koo, M, Basora, M, Pizones, J, Mora, L, Bago, J et al.
DOI: 10.1093/bja/aew434

Correction of Spinal Deformity on a Lung Transplantation Recipient.

PMID: 28038697
Journal: Spine deformity
Year: 2017
Reference: Spine Deform. 2017 Jan;5(1):72-76. doi: 10.1016/j.jspd.2016.10.001.
Impact factor: 0
Publication type: Paper in international publication
Authors: Andres Peiro, Jose Vicente, Granell, Joan Bago, Moret, Montserrat Feliu, Galdo, Antonio Moreno et al.
DOI: 10.1016/j.jspd.2016.10.001

Function and Clinical Symptoms are the Main Factors that Motivate Thoracolumbar Adult Scoliosis Patients to Pursue Surgery.

PMID: 27196023
Journal: SPINE
Year: 2017
Reference: Spine (Phila Pa 1976). 2017 Jan 1;42(1):E31-E36. doi: 10.1097/BRS.0000000000001694.
Impact factor: 2.499
Publication type: Paper in international publication
Authors: Pizones, Javier, Martin-Buitrago, Mar Perez, Perez-Grueso, Francisco Javier Sanchez, Vila-Casademunt, Alba, Alanay, Ahmet, Obeid, Ibrahim, Kleinstuck, Frank, Acaroglu, Emre R, Pellise, Ferran et al.
DOI: 10.1097/BRS.0000000000001694

Adult spinal deformity: a very heterogeneous population of patients with different needs.

PMID: 26854050
Journal: Acta Orthopaedica et Traumatologica Turcica
Year: 2016
Reference: Acta Orthop Traumatol Turc. 2016;50(1):57-62. doi: 10.3944/AOTT.2016.14.0421.
Impact factor: 0.398
Publication type: Paper in international publication
Authors: Acaroglu, Rifat Emre, Dede, Ozgur, Pellise, Ferran, Guler, Umit O, Domingo-Sabat, Montse, Alanay, Ahmet, Perez-Grueso, Francisco Sanchez et al.
DOI: 10.3944/AOTT.2016.14.0421

A decision analysis to identify the ideal treatment for adult spinal deformity: is surgery better than non-surgical treatment in improving health-related quality of life and decreasing the disease burden?

PMID: 26821143
Journal: EUROPEAN SPINE JOURNAL
Year: 2016
Reference: Eur Spine J. 2016 Aug;25(8):2390-400. doi: 10.1007/s00586-016-4413-8. Epub 2016 Jan 28.
Impact factor: 2.132
Publication type: Paper in international publication
Authors: Perez Grueso, Francesco Sanchez, Kleinstuck, Frank, Obeid, Ibrahim, Alanay, Ahmet, Pellise, Ferran, Yavuz, Yasemin, Acaroglu, Emre, Yavuz, Aysun Cetinyurek, Guler, Umit Ozgur, Yuksel, Selcen et al.
DOI: 10.1007/s00586-016-4413-8

Analysis of the reliability of surgeons' ability to differentiate between idiopathic and degenerative spinal deformity in adults radiologically. What descriptive parameters help them decide?

PMID: 26769036
Journal: EUROPEAN SPINE JOURNAL
Year: 2016
Reference: Eur Spine J. 2016 Aug;25(8):2401-7. doi: 10.1007/s00586-015-4366-3. Epub 2016 Jan 14.
Impact factor: 2.132
Publication type: Paper in international publication
Authors: Guler, Umit Ozgur, Yuksel, Selcen, Yakici, Sule, Domingo-Sabat, Montserrat, Pellise, Ferran, Perez-Grueso, Francisco J S, Obeid, Ibrahim, Kleinstuck, Frank, Acaroglu, Emre, Alanay, Ahmet et al.
DOI: 10.1007/s00586-015-4366-3

Blog

News

The work improves accuracy in predicting complications at the boundary between the instrumented spine area and the area that is left free when spinal deformity corrective surgery is performed.

Entre els projectes es troben 12 investigacions on participen investigadors i investigadores de Vall d’Hebron.

The Scoliosis Research Society (SRS) has awarded with this prestigious recognition Dr. Pellisé's team for the study on the similarity of the adverse effects of surgeries both in elderly patients and in the general adult population.

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