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Spine Research Unit

The Vall d’Hebron Spine Research Unit (VHSRU) is a growing multidisciplinary group of professionals devoted to spinal disorders with an increasing impact in terms of number of publications, associated IF and research funding. VHSRU has published 198 articles in spine field, 40% of them Q1, with a total IF of 451,9. 

Our research unit is organized in four research lines: 

  • Pediatric and adolescent deformity, 
  • Adult deformity, 
  • Spinal cord injuries,
  • Cellular therapy and new surgical techniques.

VHRSU has been involved as coordinator or collaborator in 25 funded research projects. VHRSU is currently coordinating 5 competitive projects granted by national and international institutions (Marató TV3, Eurospine, SRS, AO, GEER). One of our research projects, the European Spine Study Group (ESSG), has been very successful, with more than 60 published manuscripts and 244 podium presentations. All these projects allowed us to establish new synergies with other research centers and universities. We hope to expand this network in the future. 

Publications

Ideal sagittal profile restoration and ideal lumbar apex positioning play an important role in postoperative mechanical complications after a lumbar PSO.

PMID: 31925761
Journal: Spine deformity
Year: 2020
Reference: Spine Deform. 2020 Jun;8(3):491-498. doi: 10.1007/s43390-019-00005-3. Epub 2020 Jan 8.
Impact factor: 0
Publication type: Paper in international publication
Authors: Pizones, Javier, Perez-Grueso, Francisco Javier Sanchez, Moreno-Manzanaro, Lucia, Vila-Casademunt, Alba, Boissiere, Louis, Yilgor, Caglar, Fernandez-Baillo, Nicomedes, Sanchez-Marquez, Jose Miguel, Talavera, Gloria, Acaroglu, Emre R et al.
DOI: 10.1007/s43390-019-00005-3

The Effect of Tobacco Smoking on Adverse Events Following Adult Complex Deformity Surgery: Analysis of 270 Patients from The Prospective, Multi-center Scoli-RISK-1 study.

PMID: 31415459
Journal: SPINE
Year: 2020
Reference: Spine (Phila Pa 1976). 2020 Jan 1;45(1):32-37. doi: 10.1097/BRS.0000000000003200.
Impact factor: 2.646
Publication type: Paper in international publication
Authors: Wilson, Jamie R F, Jiang, Fan, Badhiwala, Jetan H, Shaffrey, Christopher L, Carreon, Leah Y, Cheung, Kenneth M C, Dahl, Benny T, Ames, Christopher P, Boachie-Adjei, Oheneba, Dekutoski, Mark B et al.
DOI: 10.1097/BRS.0000000000003200

Development and validation of risk stratification models for adult spinal deformity surgery.

PMID: 31252385
Journal: JOURNAL OF NEUROSURGERY-SPINE
Year: 2019
Reference: Journal of Neurosurgery: Spine. 2019 Oct;31(4):587-99. doi: 10.3171/2019.3.SPINE181452.
Impact factor: 2.998
Publication type: Paper in international publication
Authors: Pellise, Ferran, Serra-Burriel, Miquel, Smith, Justin S, Haddad, Sleiman, Kelly, Michael P, Vila-Casademunt, Alba, Sanchez Perez-Grueso, Francisco Javier, Bess, Shay, Gum, Jeffrey L, Burton, Douglas C et al.
DOI: 10.3171/2019.3.SPINE181452

Impact of resolved early major complications on 2-year follow-up outcome following adult spinal deformity surgery.

PMID: 31250173
Journal: EUROPEAN SPINE JOURNAL
Year: 2019
Reference: Eur Spine J. 2019 Sep;28(9):2208-2215. doi: 10.1007/s00586-019-06041-x. Epub 2019 Jun 27.
Impact factor: 2.513
Publication type: Paper in international publication
Authors: Nunez-Pereira, Susana, Pellise, Ferran, Vila-Casademunt, Alba, Alanay, Ahmet, Acaraglou, Emre, Obeid, Ibrahim, Sanchez Perez-Grueso, Francisco Javier, Kleinstuck, Frank et al.
DOI: 10.1007/s00586-019-06041-x

Artificial Intelligence Based Hierarchical Clustering of Patient Types and Intervention Categories in Adult Spinal Deformity Surgery: Towards a New Classification Scheme that Predicts Quality and Value.

PMID: 31205167
Journal: SPINE
Year: 2019
Reference: Spine (Phila Pa 1976). 2019 Jul 1;44(13):915-926. doi: 10.1097/BRS.0000000000002974.
Impact factor: 2.903
Publication type: Paper in international publication
Authors: Burton, Douglas, Lafage, Virginie, Schwab, Frank, Shaffrey, Christopher I Sr, Bess, Shay, Serra-Burriel, Miquel, Shaffrey, Christopher I Jr, Vila-Casademunt, Alba, Kleinstuck, Frank, Ames, Christopher P et al.
DOI: 10.1097/BRS.0000000000002974

Factors influencing patient satisfaction after adult scoliosis and spinal deformity surgery.

PMID: 31075761
Journal: JOURNAL OF NEUROSURGERY-SPINE
Year: 2019
Reference: J Neurosurg Spine. 2019 May 10;31(3):408-417. doi: 10.3171/2019.2.SPINE181486.
Impact factor: 2.998
Publication type: Paper in international publication
Authors: Boissiere, Louis, Hayashi, Kazunori, Nunez-Pereira, Susana, Bourghli, Anouar, Gille, Olivier, Vital, Jean-Marc, Pellise, Ferran, Sanchez Perez-Grueso, Francisco Javier, Kleinstuck, Frank, Acaroglu, Emre et al.
DOI: 10.3171/2019.2.SPINE181486

External Validation of the Adult Spinal Deformity (ASD) Frailty Index (ASD-FI) in the Scoli-RISK-1 Patient Database.

PMID: 29762340
Journal: SPINE
Year: 2018
Reference: Spine (Phila Pa 1976). 2018 Oct 15;43(20):1426-1431. doi: 10.1097/BRS.0000000000002717.
Impact factor: 2.792
Publication type: Paper in international publication
Authors: Miller, Emily K, Lenke, Lawrence G, Neuman, Brian J, Sciubba, Daniel M, Kebaish, Khaled M, Smith, Justin S, Qiu, Yong, Dahl, Benny T, Pellise, Ferran, Matsuyama, Yukihiro et al.
DOI: 10.1097/BRS.0000000000002717

Team Approach: Metastatic Disease of the Spine.

PMID: 29762343
Journal: JBJS reviews
Year: 2018
Reference: JBJS Rev. 2018 May;6(5):e6. doi: 10.2106/JBJS.RVW.17.00118.
Impact factor: 0
Publication type: Review in international publication
Authors: Matamalas, Antonia, Valverde, Claudia, Benavente, Sergi, Casas-Gomila, Lourdes, Romagosa, Cleofe, Gonzalez-Tartiere, Pilar, Pellise, Ferran et al.
DOI: 10.2106/JBJS.RVW.17.00118

The impact of deep surgical site infection on surgical outcomes after posterior adult spinal deformity surgery: a matched control study.

PMID: 29728924
Journal: EUROPEAN SPINE JOURNAL
Year: 2018
Reference: Eur Spine J. 2018 Oct;27(10):2518-2528. doi: 10.1007/s00586-018-5583-3. Epub 2018 May 4.
Impact factor: 2.634
Publication type: Paper in international publication
Authors: Haddad, Sleiman, Nunez-Pereira, Susana, Pigrau, Carlos, Rodriguez-Pardo, Dolors, Vila-Casademunt, Alba, Alanay, Ahmet, Acaroglu, Emre R, Kleinstueck, Frank S, Obeid, Ibrahim, Perez-Grueso, Francisco Javier Sanchez et al.
DOI: 10.1007/s00586-018-5583-3

External validation of the adult spinal deformity (ASD) frailty index (ASD-FI).

PMID: 29603013
Journal: EUROPEAN SPINE JOURNAL
Year: 2018
Reference: Eur Spine J. 2018 Sep;27(9):2331-2338. doi: 10.1007/s00586-018-5575-3. Epub 2018 Mar 30.
Impact factor: 2.634
Publication type: Paper in international publication
Authors: Neuman, Brian J, Sciubba, Daniel M, Kebaish, Khaled M, Smith, Justin S, Alanay, Ahmet, Acaroglu, Emre R, Kleinstuck, Frank, Obeid, Ibrahim, Sanchez Perez-Grueso, Francisco Javier, Carreon, Leah Y et al.
DOI: 10.1007/s00586-018-5575-3

Predictors of Health-Related Quality-of-Life After Complex Adult Spinal Deformity Surgery: A Scoli-RISK-1 Secondary Analysis.

PMID: 28259266
Journal: Spine deformity
Year: 2017
Reference: Spine Deform. 2017 Mar;5(2):139-144. doi: 10.1016/j.jspd.2016.11.001.
Impact factor: 0
Publication type: Paper in international publication
Authors: Schwab, Frank J, Carreon, Leah Y, Glassman, Steven D, Shaffrey, Christopher I, Fehlings, Michael G, Dahl, Benny, Ames, Christopher P, Matsuyama, Yukihiro, Qiu, Yong, Mehdian, Hossein et al.
DOI: 10.1016/j.jspd.2016.11.001

Intraoperative tranexamic acid use in major spine surgery in adults: a multicentre, randomized, placebo-controlled trialdagger.

PMID: 28203735
Journal: BRITISH JOURNAL OF ANAESTHESIA
Year: 2017
Reference: Br J Anaesth. 2017 Mar 1;118(3):380-390. doi: 10.1093/bja/aew434.
Impact factor: 6.238
Publication type: Paper in international publication
Authors: Colomina, M J, Koo, M, Basora, M, Pizones, J, Mora, L, Bago, J et al.
DOI: 10.1093/bja/aew434

Correction of Spinal Deformity on a Lung Transplantation Recipient.

PMID: 28038697
Journal: Spine deformity
Year: 2017
Reference: Spine Deform. 2017 Jan;5(1):72-76. doi: 10.1016/j.jspd.2016.10.001.
Impact factor: 0
Publication type: Paper in international publication
Authors: Andres Peiro, Jose Vicente, Granell, Joan Bago, Moret, Montserrat Feliu, Galdo, Antonio Moreno et al.
DOI: 10.1016/j.jspd.2016.10.001

Function and Clinical Symptoms are the Main Factors that Motivate Thoracolumbar Adult Scoliosis Patients to Pursue Surgery.

PMID: 27196023
Journal: SPINE
Year: 2017
Reference: Spine (Phila Pa 1976). 2017 Jan 1;42(1):E31-E36. doi: 10.1097/BRS.0000000000001694.
Impact factor: 2.499
Publication type: Paper in international publication
Authors: Pizones, Javier, Martin-Buitrago, Mar Perez, Perez-Grueso, Francisco Javier Sanchez, Vila-Casademunt, Alba, Alanay, Ahmet, Obeid, Ibrahim, Kleinstuck, Frank, Acaroglu, Emre R, Pellise, Ferran et al.
DOI: 10.1097/BRS.0000000000001694

Analysis of the reliability of surgeons' ability to differentiate between idiopathic and degenerative spinal deformity in adults radiologically. What descriptive parameters help them decide?

PMID: 26769036
Journal: EUROPEAN SPINE JOURNAL
Year: 2016
Reference: Eur Spine J. 2016 Aug;25(8):2401-7. doi: 10.1007/s00586-015-4366-3. Epub 2016 Jan 14.
Impact factor: 2.132
Publication type: Paper in international publication
Authors: Guler, Umit Ozgur, Yuksel, Selcen, Yakici, Sule, Domingo-Sabat, Montserrat, Pellise, Ferran, Perez-Grueso, Francisco J S, Obeid, Ibrahim, Kleinstuck, Frank, Acaroglu, Emre, Alanay, Ahmet et al.
DOI: 10.1007/s00586-015-4366-3

Blog

News

The work improves accuracy in predicting complications at the boundary between the instrumented spine area and the area that is left free when spinal deformity corrective surgery is performed.

Entre els projectes es troben 12 investigacions on participen investigadors i investigadores de Vall d’Hebron.

The Scoliosis Research Society (SRS) has awarded with this prestigious recognition Dr. Pellisé's team for the study on the similarity of the adverse effects of surgeries both in elderly patients and in the general adult population.