About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
PMID: 34632668 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2022 Reference: Eur J Neurol. 2022 Feb;29(2):469-477. doi: 10.1111/ene.15137. Epub 2021 Oct 25. Impact factor: 6.089 Publication type: Paper in international publication Authors: On, Begum Irmak, Vidal, Xavier, Berger, Ursula, Sabate, Monica, Ballarin, Elena, Maisterra, Olga, San-Jose, Antonio, Ibanez, Luisa et al. DOI: 10.1111/ene.15137
PMID: 33983413 Journal: RHEUMATOLOGY Year: 2021 Reference: Rheumatology (Oxford). 2021 Nov 3;60(11):4956-4957. doi: 10.1093/rheumatology/keab433. Impact factor: 7.58 Publication type: Editorail in international publication Authors: Selva-O'Callaghan, Albert, Simeon-Aznar, Carmen Pilar et al. DOI: 10.1093/rheumatology/keab433
PMID: 33043475 Journal: ALLERGY Year: 2021 Reference: Allergy. 2021 May;76(5):1507-1516. doi: 10.1111/all.14626. Epub 2020 Nov 4. Impact factor: 13.146 Publication type: Paper in international publication Authors: Galvan-Blasco, Paula, Sala-Cunill, Anna, Luengo, Olga, Curran, Adrian, Moreno, Nuria, Labrador-Horrillo, Moises, Guilarte, Mar, Gonzalez-Medina, Monica, Victoria, Cardona et al. DOI: 10.1111/all.14626
PMID: 33893449 Journal: EUROPEAN JOURNAL OF CLINICAL NUTRITION Year: 2021 Reference: Eur J Clin Nutr. 2021 Sep;75(9):1368-1382. doi: 10.1038/s41430-021-00913-6. Epub 2021 Apr 23. Impact factor: 4.016 Publication type: Paper in international publication Authors: Domenech, Eugeni, Julia, Antonio, Martinez-Mateu, Sergio H, Blanco, Francisco, Gratacos, Jordi, Blanco, Ricardo, Taboada, Victor Martinez, Fernandez, Emilia, Unamuno, Pablo, Gonzalez, Isidoro et al. DOI: 10.1038/s41430-021-00913-6
PMID: 33882889 Journal: BMC MUSCULOSKELETAL DISORDERS Year: 2021 Reference: BMC Musculoskelet Disord. 2021 Apr 21;22(1):372. doi: 10.1186/s12891-021-04248-y. Impact factor: 2.355 Publication type: Paper in international publication Authors: Julia, Antonio, Lopez-Lasanta, Maria, Blanco, Francisco, Gomez, Antonio, Haro, Isabel, Mas, Antonio Juan, Erra, Alba, Vivar, Ma Luz Garcia, Monfort, Jordi, Sanchez-Fernandez, Simon et al. DOI: 10.1186/s12891-021-04248-y
PMID: 32085620 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2020 Reference: Int J Mol Sci. 2020 Feb 18;21(4). pii: ijms21041372. doi: 10.3390/ijms21041372. Impact factor: 4.556 Publication type: Paper in international publication Authors: Garcia-Vives, Eloi, Sole, Cristina, Moline, Teresa, Vidal, Marta, Agraz, Irene, Ordi-Ros, Josep, Cortes-Hernandez, Josefina et al. DOI: 10.3390/ijms21041372
PMID: 31945019 Journal: JCI Insight Year: 2020 Reference: JCI Insight. 2020 Feb 13;5(3). pii: 134189. doi: 10.1172/jci.insight.134189. Impact factor: 6.205 Publication type: Paper in international publication Authors: Seto, Nickie, Torres-Ruiz, Jose Jiram, Carmona-Rivera, Carmelo, Pinal-Fernandez, Iago, Pak, Katherine, Purmalek, Monica M, Hosono, Yuji, Fernandes-Cerqueira, Catia, Gowda, Prateek, Arnett, Nathan et al. DOI: 10.1172/jci.insight.134189
PMID: 32024964 Journal: Scientific Reports Year: 2020 Reference: Sci Rep. 2020 Feb 5;10(1):1862. doi: 10.1038/s41598-020-58741-w. Impact factor: 3.998 Publication type: Paper in international publication Authors: Simeon, Carmen P, Fonollosa, Vicente, Guillen, Alfredo, Carreira, Patricia, Castellvi, Ivan, Gonzalez-Gay, Miguel A, Rios, Raquel, Callejas-Rubio, Jose Luis, Vargas-Hitos, Jose A, Garcia-Portales, Rosa et al. DOI: 10.1038/s41598-020-58741-w
PMID: 31996780 Journal: Scientific Reports Year: 2020 Reference: Sci Rep. 2020 Jan 29;10(1):1415. doi: 10.1038/s41598-020-58400-0. Impact factor: 3.998 Publication type: Paper in international publication Authors: Gomez, Nair Perez, Lopez-Mejias, Raquel, Remuzgo-Martinez, Sara, Genre, Fernanda, Pulito-Cueto, Veronica, Rozas, Sonia M Fernandez, Llorca, Javier, Fernandez, David Iturbe, Cuesta, Victor M Mora, Ortego-Centeno, Norberto et al. DOI: 10.1038/s41598-020-58400-0
PMID: 31157683 Journal: BLOOD COAGULATION & FIBRINOLYSIS Year: 2019 Reference: Blood Coagul Fibrinolysis. 2019 Jul;30(5):239-242. doi: 10.1097/MBC.0000000000000814. Impact factor: 1.12 Publication type: Paper in international publication Authors: Pardos-Gea, Jose, Martinez, Fernanda, Abrisqueta, Pau, Santamaria, Amparo, Bosch, Francesc et al. DOI: 10.1097/MBC.0000000000000814
PMID: 31151417 Journal: BMC Medical Research Methodology Year: 2019 Reference: BMC Med Res Methodol. 2019 May 31;19(1):112. doi: 10.1186/s12874-019-0746-4. Impact factor: 2.509 Publication type: Paper in international publication Authors: Vilaro, Marta, Cortes, Jordi, Selva-O'Callaghan, Albert, Urrutia, Agustin, Ribera, Josep-Maria, Cardellach, Francesc, Basagana, Xavier, Elmore, Matthew, Vilardell, Miquel, Altman, Douglas et al. DOI: 10.1186/s12874-019-0746-4
PMID: 31138531 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2019 Reference: Ann Rheum Dis. 2019 Jul;78(7):996-1002. doi: 10.1136/annrheumdis-2019-215046. Epub 2019 May 28. Impact factor: 14.299 Publication type: Paper in international publication Authors: Ollier, William E, McHugh, Neil J, Mammen, Andrew L, Betteridge, Zoe E, Tansley, Sarah L, Bowes, John, Vencovsky, Jiri, Deakin, Claire T, Danko, Katalin, Vidya, Limaye et al. DOI: 10.1136/annrheumdis-2019-215046
PMID: 30561765 Journal: HEPATOLOGY Year: 2019 Reference: Hepatology. 2019 Jun;69(6):2701-2703. doi: 10.1002/hep.30464. Epub 2019 Mar 7. Impact factor: 14.971 Publication type: Paper in international publication Authors: Senin, Alicia, Salcedo, Maria-Teresa, Merino-Casabiel, Xavier, Castells, Lluis, Esteban, Rafael, Buti, Maria, Martinez-Valle, Fernando, Gironella, Merche, Riveiro-Barciela, Mar et al. DOI: 10.1002/hep.30464
PMID: 28905404 Journal: ALLERGY Year: 2018 Reference: Allergy. 2018 Feb;73(2):323-327. doi: 10.1111/all.13306. Epub 2017 Oct 11. Impact factor: 6.048 Publication type: Paper in international publication Authors: Hoffmann, Hans Jurgen, Pfaar, Oliver, Cardona, Victoria, Demoly, Pascal, Dreborg, Sten, Fusun Kalpaklioglu, A, Klimek, Ludger, Muraro, Antonella, Popov, Todor A et al. DOI: 10.1111/all.13306
PMID: 29331045 Journal: ALLERGY Year: 2018 Reference: Allergy. 2018 Sep;73(9):1792-1800. doi: 10.1111/all.13408. Epub 2018 Jun 17. Impact factor: 6.048 Publication type: Paper in international publication Authors: DunnGalvin, Audrey, Eigenmann, Philippe A, Halken, Susanne, Hoffmann-Sommergruber, Karin, Lau, Susanne, Nilsson, Caroline, Poulsen, Lars K, Rueff, Franziska, Spergel, Jonathan, Sturm, Gunter et al. DOI: 10.1111/all.13408
PMID: 29318637 Journal: ALLERGY Year: 2018 Reference: Allergy. 2018 Jun;73(6):1322-1330. doi: 10.1111/all.13380. Epub 2018 Mar 8. Impact factor: 6.048 Publication type: Paper in international publication Authors: Worm, Margitta, Francuzik, Wojciech, Renaudin, Jean-Marie, Bilo, Maria Beatrice, Cardona, Victoria, Hofmeier, Kathrin Scherer, Kohli, Alice, Bauer, Andrea, Christoff, George, Cichocka-Jarosz, Ewa et al. DOI: 10.1111/all.13380
PMID: 29171712 Journal: ALLERGY Year: 2018 Reference: Allergy. 2018 Jan;73 Suppl 104:5-23. doi: 10.1111/all.13355. Impact factor: 6.048 Publication type: Review in international publication Authors: Pfaar, O, Bonini, S, Cardona, V, Demoly, P, Jakob, T, Jutel, M, Kleine-Tebbe, J, Klimek, L, Klysner, S, Kopp, M V et al. DOI: 10.1111/all.13355
PMID: 28283274 Journal: MEDICINA CLINICA Year: 2017 Reference: Med Clin (Barc). 2017 Jun 21;148(12):574-575. doi: 10.1016/j.medcli.2017.01.027. Epub 2017 Mar 7. Impact factor: 1.125 Publication type: Paper in national publication Authors: Fernandez-Codina, Andreu, Francisco-Pascual, Jaume, Fonollosa-Pla, Vicent et al. DOI: 10.1016/j.medcli.2017.01.027
PMID: 28277489 Journal: Scientific Reports Year: 2017 Reference: Sci Rep. 2017 Mar 9;7:43953. doi: 10.1038/srep43953. Impact factor: 4.259 Publication type: Paper in international publication Authors: Ramentol-Sintas, Marc, Gomez-Vaquero, Carmen, Raya, Enrique, Grau, Elena, Roman, Jose A, Vicente, Esther F, de Miguel, Eugenio, Lopez-Longo, Francisco J, Martinez, Lina, Morado, Inmaculada C et al. DOI: 10.1038/srep43953
PMID: 28263001 Journal: JOURNAL OF BONE AND MINERAL RESEARCH Year: 2017 Reference: J Bone Miner Res. 2017 Jul;32(7):1575-1581. doi: 10.1002/jbmr.3121. Epub 2017 May 11. Impact factor: 6.284 Publication type: Paper in international publication Authors: Herrera, Sabina, Perez-Lopez, Jordi, Molto-Abad, Marc, Guerri-Fernandez, Roberto, Cabezudo, Elena, Novelli, Silvana, Esteve, Jordi, Hernandez, Albert, Roig, Inmaculada, Solanich, Xavier et al. DOI: 10.1002/jbmr.3121
PMID: 28248800 Journal: JCR-JOURNAL OF CLINICAL RHEUMATOLOGY Year: 2017 Reference: J Clin Rheumatol. 2017 Apr;23(3):155-159. doi: 10.1097/RHU.0000000000000500. Impact factor: 1.322 Publication type: Paper in international publication Authors: Selva-O'Callaghan, Albert, Marin, Ana, Escola-Verge, Laura, Pinal-Fernandez, Iago, Fernandez-Codina, Andreu, Callejas-Moraga, Eduardo L, Espinosa, Juan, Labrador-Horrillo, Moises et al. DOI: 10.1097/RHU.0000000000000500
PMID: 25386668 Journal: ANTIOXIDANTS & REDOX SIGNALING Year: 2015 Reference: Antioxid Redox Signal. 2015 Mar 10;22(8):679-85. doi: 10.1089/ars.2014.6181. Epub 2014 Dec 18. Impact factor: 7.407 Publication type: Paper in international publication Authors: Cordero, Mario D, Castro-Marrero, Jesus, Roman-Malo, Lourdes, Aliste, Luisa, Fernandez de Sevilla, Tomas, Alegre-Martin, Jose, Segundo, MJ, Calvo, Natalia, Saez-Francas, Naia et al. DOI: 10.1089/ars.2014.6181
PMID: 24773767 Journal: CLIN EXP RHEUMATOL Year: 2014 Reference: Clin Exp Rheumatol. 2014 May-Jun;32(3):404-7. Epub 2014 Apr 28. Impact factor: 2.973 Publication type: Clinical Trials Authors: Castella-Fierro, E, Martinez-Gomez, X, Vilardell-Tarres, Miquel, Selva-O'Callaghan, A, Pallisa Nunez, E, Pinal Fernandez, I et al. DOI:
PMID: 25110305 Journal: SEMIN ARTHRITIS RHEU Year: 2014 Reference: Semin Arthritis Rheum. 2014 Dec;44(3):331-7. doi: 10.1016/j.semarthrit.2014.07.002. Epub 2014 Jul 15. Impact factor: 3.629 Publication type: Paper in international publication Authors: Guillen-Del Castillo, Alfredo, Pilar Simeon-Aznar, Carmen, Fonollosa-Pla, Vicent, Alonso-Vila, Serafin, Reverte-Vinaixa, Maria M, Munoz, Xavier, Pallisa, Esther, Selva-OCallaghan, Albert, Fernandez-Codina, Andreu, Vilardell-Tarres, Miquel et al. DOI: 10.1016/j.semarthrit.2014.07.002
PMID: 24711435 Journal: NEPHROL DIAL TRANSPL Year: 2014 Reference: Nephrol Dial Transplant. 2014 Sep;29(9):1740-9. doi: 10.1093/ndt/gfu062. Epub 2014 Apr 7. Impact factor: 3.488 Publication type: Paper in international publication Authors: Torres-Salido, Maria Teresa, Cortes-Hernandez, Josefina, Vidal, Xavier, Pedrosa Anna, Vilardell-Tarres, Miquel, Ordi-Ros, Josep et al. DOI: 10.1093/ndt/gfu062
PMID: 24699394 Journal: AUTOIMMUN REV Year: 2014 Reference: Autoimmun Rev. 2014 Aug;13(8):880-1. doi: 10.1016/j.autrev.2014.03.003. Epub 2014 Apr 1. Impact factor: 7.095 Publication type: Letter whit IF Authors: Fonollosa-Pla, V, Simeon-Aznar, C, Garcia de Tena, J, Bernal-Bello, D et al. DOI: 10.1016/j.autrev.2014.03.003
PMID: 21905008 Journal: ARTHRITIS AND RHEUMATISM Year: 2012 Reference: Arthritis Rheum. 2012 Jan;64(1):264-71. doi: 10.1002/art.33325. Impact factor: 7.866 Publication type: Paper in international publication Authors: Camps, Mayte, Vonk, M C, Knaapen, H, Beretta, L, Rueda, B, Hesselstrand, R, Herrick, A, Worthington, J, Hunzelman, N, Denton, C P et al. DOI: 10.1002/art.33325
PMID: 21832821 Journal: RESPIRATION Year: 2012 Reference: Respiration. 2012;83(3):239-44. Epub 2011 Aug 11. Impact factor: 2.258 Publication type: Letter whit IF Authors: , , , , , , , et al. DOI: 10.1159/000329440
PMID: 22133713 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2012 Reference: Arch Bronconeumol. 2012 Jan;48(1):8-13. Epub 2011 Nov 30. Impact factor: Publication type: Letter or abstract Authors: , , , , , , et al. DOI: 10.1016/j.arbres.2011.06.010
PMID: 22122552 Journal: DERMATOLOGIC SURGERY Year: 2012 Reference: Dermatol Surg. 2012 Jan;38(1):38-47. doi: 10.1111/j.1524-4725.2011.02221.x. Epub 2011 Nov 28. Impact factor: 1.798 Publication type: Paper in international publication Authors: , , , et al. DOI: 10.1111/j.1524-4725.2011.02221.x
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
The study showing how thrombocytopenia increases the risk of thrombosis in patients with antiphospholipid syndrome has been considered the best paper published in 2021.
