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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Publications

Relapse rate and renal prognosis in ANCA-associated vasculitis according to long-term ANCA patterns.

PMID: 33020895
Journal: CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Year: 2021
Reference: Clin Exp Immunol. 2021 Feb;203(2):209-218. doi: 10.1111/cei.13530. Epub 2020 Nov 2.
Impact factor: 4.33
Publication type: Paper in international publication
Authors: Oristrell, Joaquim, Loureiro-Amigo, Jose, Solans, Roser, Valenzuela, Ma Pau, Monsalvez, Victor, Segarra, Alfons, Amengual, Ma Jose, Marin, Ana, Feijoo, Carlos, Tolosa, Carles et al.
DOI: 10.1111/cei.13530

Omalizumab for the treatment of Chronic Inducible Urticaria in 80 patients.

PMID: 32730636
Journal: BRITISH JOURNAL OF DERMATOLOGY
Year: 2021
Reference: Br J Dermatol. 2021 Jan;184(1):167-168. doi: 10.1111/bjd.19425. Epub 2020 Sep 2.
Impact factor: 9.302
Publication type: Letter or abstract
Authors: Gimenez-Arnau, A, Fernandez Chico, N, Guilabert Vidal, A, Sala Cunill, A, Exposito-Serrano, V, Curto Barredo, L, Aguilera Peiro, P, Gomez Armayones, S, Serra-Baldrich, E, Spertino, J et al.
DOI: 10.1111/bjd.19425

Efficacy and Safety of PCSK9 Inhibitors in Hypercholesterolemia Associated With Refractory Nephrotic Syndrome.

PMID: 33426389
Journal: Kidney International Reports
Year: 2021
Reference: Kidney Int Rep. 2020 Oct 12;6(1):101-109. doi: 10.1016/j.ekir.2020.09.046. eCollection 2021 Jan.
Impact factor: 4.164
Publication type: Paper in international publication
Authors: Jatem, Elias, Lima, Joan, Montoro, Bruno, Torres-Bondia, Francisco, Segarra, Alfons et al.
DOI: 10.1016/j.ekir.2020.09.046

ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice.

PMID: 32512619
Journal: ALLERGY
Year: 2021
Reference: Allergy. 2021 Jan;76(1):168-190. doi: 10.1111/all.14422. Epub 2020 Oct 23.
Impact factor: 13.146
Publication type: Review in international publication
Authors: Bouchard, Jacques, Bousquet, Jean, Anto, Josep M, Bachert, Claus, Haahtela, Tari, Zuberbier, Torsten, Czarlewski, Wienczyslawa, Bedbrook, Anna, Bosnic-Anticevich, Sinthia, Walter Canonica, G et al.
DOI: 10.1111/all.14422

Blog

News

The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.

Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.

It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.