Speaker: Dr. Silvia De Santis, Group leader Translational Imaging Biomarkers. Instituto de Neurociencias (CSIC-UMH), San Juan de Alicante, Spain

Abstract: Neuroinflammation and neurodegeneration are hot topics for brain research, and promising targets for the development of novel treatments with potential for intervention in pathological conditions like multiple sclerosis. Non-invasive biomarkers are needed to characterise both aspects of brain tissue, both in preclinical models and in humans. This talk will discuss recent advances from the group, going in the direction of developing new neuroimaging tools to understand brain microstructural trajectories linked to these cellular processes in both healthy ageing and degeneration, and the association between such trajectories, risk factors and favorable functional outcomes. To achieve this aim, the chosen framework is based on diffusion-weighted magnetic resonance imaging, validated through cell-specific manipulations and potentiated through artificial intelligence

Host: Dr. Deborah Pareto Onghena, Main researcher Neuroradiology, Vall Hebron Institut de Recerca (VHIR)

Online attendance: https://gencat.zoom.us/j/88526227387