About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Speaker: Maria Teresa Buongiorno. Research Group on Neurovascular Diseases of the Vall d'Hebron Research Institute (VHIR).
Brief CV: For the past 20 years I have dedicated my professional career to the care of patients with movement disorders and dementias at university hospitals. Concurrently, my research activities have focused on the clinical, biological, and neuroimaging factors associated with the development of cognitive impairment in Alzheimer's disease and alpha-synucleinopathies, with special interest in the involvement of the glymphatic system. I am engaged in professional and research activities at Vall d'Hebron University Hospital.
Abstract: The glymphatic system is a recently described functional system involved in the clearance of brain waste. Its functional unit is composed by the astrocytes, containing aquaporin 4 water channels, perivascular spaces, and capillaries. It has been suggested that it has a key role in the etiology and progression of neurodegenerative diseases. In this talk, I will briefly review through the available preclinical and clinical evidence, how hemodynamic factors, genetic variability, pharmacological modulation and neuroinflammation modify the glymphatic function. A global research framework integrating all of these factors will be proposed highlighting knowledge gaps and new hypotheses.
Register here to attend by Zoom:
https://gencat.zoom.us/j/99358396052
