The "http://www.fundaciontatianapgb.org/" Tatiana Pérez de Guzmán el Bueno Foundation has granted with one out of the eight neuroscience research grants Dr. Ariadna Laguna, researcher of the Neurodegenerative Diseases group at Vall d’Hebron Institute of Research (VHIR). The project, entitled “Study of the transcriptional profile in a sub-group of prodromal patients with Partinson’s disease”, will last 3 years and has been funded with 40,000 euros.The aim of the study is to identify molecular pathways, genes and microRNAs deregulated in two types of patients who have not displayed yet the motor symptoms, but have already suffered other changes that precede the onset of the disease. In order conduct the study, Dr. Laguna will carry out a cutting edge RNA sequencing technique from isolated neurons of post-mortem brain tissue from both groups of patients. With the results of the study, VHIR researcher expects that “we could better understand the etiology and pathogenesis of the disease and correlate the transcriptional changes with the clinical and neuropathological data”. Despite the latest advances in Parkinson’s disease research, the only treatment available is symptomatic and is yet far away to avoid the onset of the disease and its progression.