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24/10/2018

Dr. Chaysavanh Manichanh takes part in an international multicentric study to decipher the fungus-host-microbiota interplay

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24/10/2018

Dr. Chaysavanh Manichanh has been selected to be part of a European project which aims to train researchers through a network of 18 centers from 7 different countries.

Dr. Chaysavanh Manichanh, head of the Microbiota laboratory of the http://en.vhir.org/portal1/grup-equip.asp?s=recerca&contentid=187018 Physiology and Pathophysiology of the Digestive Tract research group at VHIR, has been selected to be part of a European project, where she will be responsible for the Work Package "Impact of the microbiota-host interplay on the severity of fungal infection". The project is part of the Innovative Training Networks (ITN) from the Marie Curie Actions under the Horizon 2020 European programme and aims to train a new generation of researchers in interdisciplinary and translational skills through a network of 18 centers in 7 different countries.The project, entitled "Deciphering the fungus-host-microbiota interplay to improve the management of fungal infections" (FunHoMic), will integrate for the first time experts in fungal pathogenesis, immunology, microbial ecology and omics technologies that will train 13 Early Stage Researchers (ESRs) who will define and exploit this Fungal-Host-Microbiota interplay to identify novel biomarkers for the stratification of a patient's risk of serious fungal infection.Fungal infections have a major impact on human health, infecting about 2 billion people and having a higher mortality each year than malaria or breast cancer. One of the most common causes of this type of infection is candidiasis, a fungal infection caused by Candida species and potentially fatal when they enter the bloodstream, a major problem for vulnerable hospitalized patients.This project, which starts in 2019, has a duration of 4 years and a budget of 3.5 million euros that will be used entirely for the training of researchers. It is coordinated by Institut Pasteur and unites academic partners from France, Germany, The Netherlands, Switzerland, Spain and UK, a French Technology Research Institute with cutting-edge omics technology platforms, and three SMEs from The Netherlands, Belgium and France that will provide unrivalled organ-on-chip and gastro-intestinal tract simulation technologies.The project will pave the way for precision medicine in patient management through preventive or therapeutic interventions using antifungals, immune modulators or Live Biotherapeutic Products (LBPS) and will allow Europe to remain at the forefront of translational research in the field of medical mycology.A position as a predoctoral researcher (Bioinformatician - Statistician) will be soon posted.

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