Employees from the Catalan company of innovative products, "http://www.industex.com/" Industex, returned to Vall d’Hebron Institute of Research (VHIR) in order to see the results of the 50,000 euros donation that co-funded in 2012 the first INCOMED call. The staff visited the lab of Dr. Rosanna Paciucci, researcher from the Translational Biomedical Research in Urology Group. In this lab also works Dr. Carlos Fernández, who received the "http://www.vhir.org/salapremsa/noticies/noticies_detall.asp?Idioma=en&mv1=5&mv2=3&mh1=0&mh2=0&mh3=0&mh4=0&ms=0&any=2013&num=255" INCOMED grant thanks to Industex. In Dr. Paciucci’s lab, they investigate prostate cancer, which is the most frequent cancer in men in western Countries and the second leading cause of death for cancer in Europe. The advanced metastatic cancer is still a major unresolved problem. In their lab, they have investigated the actions of the oncogenic protein prostate tumor overexpressed-1, PTOV1, that they discovered for its high expression in aggressive tumors and significantly associated with poor prognosis in prostate, breast, bladder, ovary and liver cancers. They have recently described two mechanisms of action for this protein that are implicated in prostate cancer progression. Thanks to the collaboration with Industex, they have discovered an additional action for this protein that is linked to its ability to repress a major tumor suppressor gene. These results further confirm PTOV1 as a significant target for future, more specific therapies in metastatic prostate cancer. "http://www.faigrecerca.org/noticies-vhir2.php?id=25" Industex employees also visited VHIR in 2013. "http://www.faigrecerca.org/noticies-vhir2.php?id=25"