The second Vall d'Hebron Research Institute (VHIR) Health Innovation Contest, in which have taken part all the Catalan Institute of Health (ICS) hospitals and Catalan research centres accredited by the Institute of Health Carlos III (ISCIII) and the Medical Technology Innovation Platform (ITEMAS), already has winners after an awards ceremony that took place at VHIR today.The first prize in Biomedical Research Innovation category, a price of 5,000 euros, has been given to 'Pushing Myc inhibition to the clinic using cell penetrating peptides' project, led by Laura Soucek from the Mouse Models of Cancer Therapies group from the Vall d'Hebron Institute of Oncology (VHIO). The project aims to develop a new therapeutic option for pacients with cancer by targeting Myc protein with an inhibitor peptide, Omomyc, a new pharmaceutical entity. This shows very promising preclinical data as a novel therapy. It is expected that its application as cell penetrating peptide increases the therapeutic options against many human cancers.The first prize in Healthcare practice Innovation category, also a price of 5,000 euros, has been given to 'Development of a surgical device for sutureless vascular anastomosis' led by Jordi Descarrega, from the Plastic, Reconstructive and Aesthetic Surgery Unit of the Hospital Clinic. The initial phase designed device is thought for plastic surgery. Specifically in free flaps vascular sutures where anastomosis performed in small calibre vessels and the conventional suture is especially difficult and has higher failure risk. However, it is expected that it could be used in other surgical procedures since it could be applied in other surgical specialities, as maxillofacial surgery, ENT, cardiovascular surgery or organ transplantation.The second prize in Biomedical Research Innovation category, a price of 2,500 euros, has been given to 'Liver on a chip' led by Jordi Gracia-Sancho, from the IDIBAPS liver hemodynamics group. They have been working in designing and manufacturing of a microfluidic camera that simulates hepatic microcirculation. This novel research would be useful as a study and diagnostic in vitro tool for cell function, pharmacology, toxicity and personalised medicine. It could be applied to all the biomedical research where vascular system is important (liver, kidney, cardiovascular, etc).Regarding the Healthcare Practice category, the second prize has been given to 'Neonatologist at Home (NoaH) - premature babies tele-monitoring premature babies', a project led by Albert Pla from the Pediatric Endocrinology group from Girona Institute for Biomedical Research (IdiBGi). It has also won a 2,500 euros prize. The aim of the project is to help premature babies monitoring under a domiciliary hospitalization programme through mobile technology and artificial intelligence new technologies. The NoaH application with wireless sensors allows measuring vital signs and collect important clinical information provided by parents.It is important to highlight special mention to the project with better product definition: 'Thoracic retention and safety device' lead by Javier J. Pérez Acebo from Parc Taulí Institute of Health Research and Innovation. This novel device is used in patients with psychomotor agitation/drug intoxication in order to avoid self-heteroagressivity. Finally, while the presentation of the 20 projects, the attendees have voted via Twitter with #concursvhir hashtag for the best presentation. It has won Jordi Garcia-Sancho, from the IDIBAPS liver hemodynamics group for the presentation 'Liver on a chip'. The hashtag #concursvhir has been top ten trending topic during the morning in Spain.The second edition of the contest has been a success as is shown by the 67 projects presented, 44 derived from healthcare practice and 23 from biomedical research. The projects, in which 234 professionals, 173 healthcare workers and 93 biomedical research had taken part, come from 13 hospitals and 22 research centres, universities and foundations, which reveals that it has had a great involvement and a wide provenances variety. The VHIR Innovation Contest has become the Catalan Innovation Contest. To make it possible, it has been key the collaboration of 33 health-related companies and 8 public institutions that support the project.Furthermore, interesting roundtables, innovation world discussions and a networking with companies, investors and contest project's authors have taken place at the end of the contest.Public health, economy and education department authorities attended the as well as ACCIó and Roche, the contest's key drivers, together with VHIR and hospital leaders.