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21/05/2012

Researchers discover a new family of key mitochondrial proteins for the function and viability of the brain

2012_0094_2012_0094_IMATGE

21/05/2012

A team headed by Eduardo Soriano at the Institute for Research in Biomedicine has published a study in Nature Communications describing a new family of six genes whose function regulates the movement and position of mitochondria in neurons. Many neurological conditions, including Parkinson’s and various types of Charcot-Marie-Tooth disease, are caused by alterations of genes that control mitochondrial transport, a process that provides the energy required for cell function.Researchers of the neuromuscular and mitochondrial pathology group at Vall d'Hebron Research Institute (VHIR), Dr. Antoni Andreu and Dr. Elena García Arumí, have contributed with this work in the study of the paper of these proteins of the mitochondrial function, both at the bioenergetic level as well as at the maintenance of the mitochondrial DNA. This set of new genes expresses highly in the nervous system with a specific and crucial function for its activity and viability. Besides its possible participation in the cerebral pathologies, these proteins might be related to metabolic diseases and cancer.

A team headed by Eduardo Soriano at the Institute for Research in Biomedicine has published a study in Nature Communications describing a new family of six genes whose function regulates the movement and position of mitochondria in neurons. Many neurological conditions, including Parkinson’s and various types of Charcot-Marie-Tooth disease, are caused by alterations of genes that control mitochondrial transport, a process that provides the energy required for cell function.Researchers of the neuromuscular and mitochondrial pathology group at Vall d'Hebron Research Institute (VHIR), Dr. Antoni Andreu and Dr. Elena García Arumí, have contributed with this work in the study of the paper of these proteins of the mitochondrial function, both at the bioenergetic level as well as at the maintenance of the mitochondrial DNA. This set of new genes expresses highly in the nervous system with a specific and crucial function for its activity and viability. Besides its possible participation in the cerebral pathologies, these proteins might be related to metabolic diseases and cancer.

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