Dr. Cristina Dopazo Taboada, associate surgeon of the Hepatobiliara (HBP) Surgery and Transplantation Service of the Vall d'Hebron University Hospital, has recently been awarded a fellowship for multicenter research projects, awarded by the Spanish Association of Surgeons (AEC) with a total amount of euros 10,000, for the work Applicability of Hepatic Transplantation to Unresectable Perihilar Cholangiocarcinoma. Potential Prognostic Biomarkers. Multicenter Study.The AEC defined itself as a non-profit scientific society, which aims to contribute to the progress of surgery in all its aspects, promoting training. As well as the development and professional improvement of surgeons, seeking the best quality of care for patients and promoting teaching and research, with highly prestigious projects such as the one granted to Dr. Dopazo.Thanks to this fellowship, the doctor will have the opportunity to validate the results obtained from the care protocol based on a neoadjuvant chemo-radiotherapy treatment followed by liver transplantation to treat patients with unresectable perihilar cholangiocarcinoma without lymph node or distant metastases, which the centers of liver transplantation in Catalonia, that is, the Clínic Hospital, the Bellvitge University Hospital and the Vall d'Hebron University Hospital, established in 2007. In fact, the doctor herself points out that "after obtaining good results with a small group of patients, the idea is to verify these results in a larger cohort within a prospective and multicenter study in which several groups of liver transplantation participate nationwide"."Another differential point of our study is the inclusion of the analysis of the molecular profile of the cholangiocarcinoma in the explant specimen, thanks to the collaboration of Dr. Helena Verdaguer, medical oncologist of the Vall d'Hebron Institute of Oncology (VHIO), and of the VHIO itself. This will make it possible to identify target mutations that allow the tumor to be correlated with a more or less favorable biological behavior with long-term prognostic implications", adds Cristina Dopazo.The research, which hopes to obtain results in the next five years, aims to demonstrate that, in a selected group of patients diagnosed with unresectable perihilar cholangiocarcinoma, the combined treatment of chemo-radiotherapy and liver transplantation can prolong long-term survival, compared to current results achieved with palliative systemic treatment. In addition, the doctor explains that "the analysis of biomarkers will help a deeper understanding of this type of tumor and a better selection of patients".Dr. Dopazo recognizes the difficulty of obtaining a fellowship like this one. "I am very excited, since it is a recognition of the work that the different groups involved are doing and a further boost to continue advancing in the investigation".