The FIBROWALK study, led by the Vall d'Hebron Rheumatology Service, has shown the effectiveness of a multicomponent treatment for patients with fibromyalgia, based on education in pain neuroscience, exercise, cognitive behavioral therapy and mindfulness.Fibromyalgia is a disease characterized by chronic pain, especially in the muscles and joints, and has a strong impact on activities of daily living. It currently affects around 2% of the population - mostly women - and represents a significant burden on the health system in many countries. This disease responds very little to pharmacological treatment. Therefore, being able to demonstrate the effectiveness of a combined non-pharmacological treatment for these patients is a very important step to be able to reduce the impact of the disease. This is what a group of researchers have proposed, led by the Rheumatology Service of the Vall d'Hebron University Hospital, who thanks to the FIBROWALK study have been able to demonstrate the effectiveness of a multicomponent treatment for patients with education-based fibromyalgia in neuroscience of pain, exercise, cognitive behavioral therapy, and mindfulness. The results, which have been published in the https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603188/ Journal of Clinical Medicine, have shown that, in general, this multicomponent approach, coupled with usual treatment (medication and minimum education and exercise guidelines), is significantly more effective than regular treatment alone for this type of people.Because fibromyalgia is a complex multidimensional disease, involving a wide variety of predisposing factors, the results of the study recommend a multicomponent approach, combining pharmacological and non-pharmacological treatments. "We have been doing the therapy that has been studied in Vall d'Hebron for some time as a regular treatment for people with fibromyalgia", explains Dr. Mayte Serrat, from the Expertise Unit in Central Sensitization Syndromes of the Rheumatology Service and principal investigator of the study. "The techniques we have carried out outside the hospital, in a natural environment, help these people to divert their attention from the strong thoughts they have about their pain. To date, there have been no studies that brought together these four components that we implement (pain neuroscience education, therapeutic exercise, cognitive-behavioral therapy, and mindfulness). In addition, we have shown that they represent an improvement in all the variables we have studied: patients improve in pain, fatigue, the impact of the disease, anxiety, depression and kinesophobia". Currently, the treatment cannot be done outside with the support of health professionals, due to the pandemic. However, the Rheumatology Service continues the same therapy but explained through videos they send to patients.Dra. Miriam Almirall, coordinator of the Expertise Unit in Central Sensitization Syndromes of the Rheumatology Service, highlights the fact that this study can mean a paradigm shift by providing a new approach to this pathology. "This is the first study in which multicomponent treatment is so complete and the first to show the effectiveness of the combined result of these therapies". She adds: "Fibromyalgia has a very high prevalence, so we would like to be able to help implement this treatment throughout the territory so that many more people benefit". Finally, Dra. Sara Marsal, head of the Rheumatology Service and of the Rheumatology research group at the Vall d'Hebron Research Institute (VHIR), stresses the importance of having carried out this pioneering study as "it has proven to be an effective treatment, which opens a new reference therapeutic strategy that will undoubtedly be adopted in other centers".