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16/01/2014

VHIR brings closer System Biology to the clinical practice

2014_0008_2014_0008_IMATGE

16/01/2014

Researchers will have within reach the integral analysis of the patient’s profile thanks to the agreement with Anaxomics

Vall d’Hebron Institute of Research (VHIR) and "http://www.anaxomics.es/" Anaxomics Biotech have signed an agreement to provide the use of systems biology techniques to the VHIR research groups, allowing the application of this innovative approach in the usual clinical practice.Systems biology allows the integration in a single analysis of all the information of patients, including both clinical data (clinical profile, received treatments, results of routine marker analysis) and “omics” data obtained in proteomics, genomics and metabolomics studies, whose cost per patient is constantly decreasing and which many times becomes indispensable for research projects. The integration of this huge quantity of data and its later interpretation require very specific tools and knowledge.The agreement with Anaxomics broadens the portfolio of services of "http://www.vhir.org/serveis/UAT/presentacioserveis.asp?mv1=3&mv2=1&mh1=3&mh2=1&mh3=1&a=20&g=3&Idioma=en" "http://www.vhir.org/serveis/UAT/presentacioserveis.asp?mv1=3&mv2=1&mh1=3&mh2=1&mh3=1&a=20&g=3&Idioma=en" VHIR’s Unit of High Technology since it provides the researchers with personalized consulting services to identify molecular mechanisms associated with a disease or a drug by integrating clinical and molecular biology databases, and also offers an automated service through the "http://www.simscells.com/" SIMScells web platform where the researchers can introduce their experimental data and conduct simple analyses.According to the VHIR’s director, Dr. Joan X. Comella, this type of technology “is essential to foster a better understanding of the molecular mechanisms whose alteration is the origin of different pathologies, and also to improve the personalized treatment of the patients according to their personal characteristics. Moreover, the Anaxomics’ CEO, Dr. José Manuel Mas, states that the variations of the mechanism of action in the same drug administered to different patients could determine its efficiency and toxicity, but affirms that “now we have tools to start mapping what happens in each patient and we will make them available to doctors and researchers”.The profile analysis of a patient through systems biology techniques is commonplace in world renown hospitals, such as Memorial Sloan-Kettering Cancer Center or Mount-Sinai in New York, where it forms part of a protocol of treatment assignment for patients with certain cancers.

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