Santiago Ramon y Cajal Agüeras Institucions de les que formen part Cap de grup Patologia molecular translacional Vall Hebron Institut de Recerca Email Santiago Ramon y Cajal Agüeras Email Institucions de les que formen part Cap de grup Patologia molecular translacional Vall Hebron Institut de Recerca
Línies de recerca Study of Cell Signalling pathway in human tumors. Identification of funnel factors. We have characterized the levels of activation in Cell Signalling in a spectrum of solid tumors and correlated the levels of various factors, including mTOR and downstream proteins (p70S6K, S6, 4EBP1, eIF4E) with prognosis and grade of malignancy. Also, are being characterized, at the molecular level, the factors involved in controlling the translation cap dependent and independent in malignant tumors. IP: Santiago Ramon y Cajal Agüeras Study of gene expression of senescence in human tumors The expression of mARN genes identified by Dr.R. Bernards has been studied in normal and tumor tissue of cancer patients. This study identifies for the first time, RSK4 and KIAA0828 genes as genes whose role may be relevant in cancer. The expression of these genes is being studied in protein by Western blot and immunohistochemistry. Also are characterizing the biochemical pathways where these genes may be involved IP: Santiago Ramon y Cajal Agüeras Identification of molecular targets associated with tumor progression and therapy resistance in colorectal carcinoma. Studying in colorectal cancer mechanisms of action of the central signal transduction pathways, identify potential molecular alterations that can be used as therapeutic targets and characterize the degree of genetic inestability. IP: Santiago Ramon y Cajal Agüeras Projectes CancerScan: Smart pathology slide scanner for diagnosis and patient-specific treatment recommendation in oncology IP: Santiago Ramon y Cajal Agüeras Col·laboradors: - Entitat finançadora: EUROPEAN COMMISSION Finançament: 609600 Referència: EC/PATHFINDER_OPEN/2024/RAMON_Y_CAJAL Durada: 01/08/2025 - 31/07/2028 CancerScan: Smart pathology slide scanner for diagnosis and patient-specific treatment recommendation in oncology IP: Santiago Ramon y Cajal Agüeras Col·laboradors: Joaquin Seras Franzoso, CancerScan: Smart pathology slide scanner for diagnosis and patient-specific treatment recommendation in oncology, CancerScan: Smart pathology slide scanner for diagnosis and patient-specific treatment recommendation in oncology, Sandra Mancilla Zamora, Marc Miquel Moltó Abad, Gisela Espriu Aguado, Sonia Borao Arriazu Entitat finançadora: EUROPEAN COMMISSION Finançament: 609600 Referència: CANCERSCAN_RAMON Y CAJAL_EC/PATHFINDER_OPEN2024 Durada: 01/08/2025 - 31/07/2028 MNK - EB1 IP: Santiago Ramon y Cajal Agüeras Col·laboradors: Inés de Torres Ramirez, Adriana Martinez Cifuentes, Sara Garcia Ortega, Elena Muro Blanc, Marta Cano Galietero, Vicente Peg Camara, Stefan Hummer Entitat finançadora: Generalitat de Catalunya - Departament de Salut Finançament: 189970 Referència: SLT036/24/000026 Durada: 21/12/2024 - 20/12/2026 Synthetic Data Generation Framework for Integrated Validation of Use Cases and AI Healthcare Applications IP: Manuel Escobar Amores Col·laboradors: Santiago Ramon y Cajal Agüeras, Aitor Rodriguez Martinez, Javier Hernandez Losa, Sonia Borao Arriazu Entitat finançadora: EUROPEAN COMMISSION Finançament: 163125 Referència: SYNTHIA_M.ESCOBAR_HE-JU-IHI_2023 Durada: 01/09/2024 - 31/08/2029 Paginació Pàgina actual 1 Page 2 Page 3 Page 4 Page 5 … Pàgina següent › Última pàgina »