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Ariadna Boloix Amenós

I am a postdoctoral researcher in the group of Childhood Cancer and Blood Disorders. Specifically, I am working on project based on the development and implementation of RNA-based therapies in clinical practice for the treatment of pediatric solid tumors.

Institutions of which they are part

Postdoctoral researcher
Childhood Cancer and Blood Disorders
Vall Hebron Institut de Recerca

Ariadna Boloix Amenós

Institutions of which they are part

Postdoctoral researcher
Childhood Cancer and Blood Disorders
Vall Hebron Institut de Recerca

I am a postdoctoral researcher in the group of Childhood Cancer and Blood Disorders. Specifically, I am working on project based on the development and implementation of RNA-based therapies in clinical practice for the treatment of pediatric solid tumors.

I graduated in Pharmacy at the University of Barcelona and next year I studied a master's degree in Biomedicine. In 2015 I started my PhD thesis in collaboration between the Childhood Cancer and Blood Disorders group of VHIR and the Nanomol group of ICMAB-CSIC. Since 2019 when I defended the thesis, I continued working in the preclinical development of a nanomedicine based on the use of lipidic nanoparticles conjugated to microRNAs for the treatment of neuroblastoma as well as other diseases that can be treated with RNA-based therapies. The results of this research are patented (WO2020229469) and are currently pending review for publication in the scientific journal Small.
The nucleic acid administration platform developed in the group has generated the interest of different national or International research groups with which we collaborated or are collaborating.
So far, my purpose has been to advance the levels of technological readiness (TRL) of microRNA-based nanomedicine, which has been carried out while participating in entrepreneurship and innovation programs (Seed Knowledge Grants Program 2018; Bcn Activa Pre-acceleration Program and Ignite Health Program organized by Biocat).
Finally, to complement my training in relevant clinical preclinical studies and improve my knowledge of technology transfer, I began a postgraduate specialization in quality management (UOC).

Projects

NEW NANOTOOLS FOR THE TREATMENT OF METASTATIC NEUROBLASTOMA

IP: Miguel Segura Ginard
Collaborators: Ariadna Boloix Amenós
Funding agency: Instituto de Salud Carlos III
Funding: 208120
Reference: PI20/00530
Duration: 01/01/2021 - 31/12/2023

Quatsomes as a novel nanomaterial platform for nucleic acids delivery

IP: Miguel Segura Ginard
Collaborators: Aroa Soriano Fernández, Ariadna Boloix Amenós, Lucas Moreno Martín-Retortillo
Funding agency: Instituto de Salud Carlos III
Funding: 83600
Reference: DTS20/00018
Duration: 01/01/2021 - 31/12/2022

Investigació translacional en càncer infantil (GRE)

IP: Josep Sánchez de Toledo Codina
Collaborators: Investigació translacional en càncer infantil (GRE) , Aroa Soriano Fernández, Maria Cristina Díaz de Heredia Rubio, Miguel Segura Ginard, Anna Llort Sales, Raquel Hladun Alvaro, Ariadna Boloix Amenós, Laura Alonso Garcia, Josep Roma Castanyer
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 30000
Reference: 2014 SGR 660
Duration: 01/01/2014 - 31/12/2016

Related news

"Generation of a bank of surgical orthotopic PDX (patient-derived xenografts) models within the framework of a personalized medicine program in pediatric cancer" was the awarded work, of the Childhood Cancer and Hematological Diseases Group of VHIR.

A study, co-led by Vall d’Hebron, has analysed the evolution of clinical trials with children and adolescents with cancer over the last 15 years, with the aim of optimising efficacy and defining lines for further progress.

The research team has shown that inhibiting the TRIB3 protein slows the growth of rhabdomyosarcoma and improves survival in animal models.

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