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Ariadna Laguna Tuset

I am a neuroscientist with extensive experience in the molecular mechanisms underlying both neurodevelopmental and neurodegenerative diseases of the nervous system. My current research is aimed at identifying new therapeutic targets and biomarkers to improve the diagnosis and treatment of Parkinson's disease.

Institutions of which they are part

Main researcher
Neurodegenerative Diseases
Vall Hebron Institut de Recerca

Ariadna Laguna Tuset

Institutions of which they are part

Main researcher
Neurodegenerative Diseases
Vall Hebron Institut de Recerca

I am a neuroscientist with extensive experience in the molecular mechanisms underlying both neurodevelopmental and neurodegenerative diseases of the nervous system. My current research is aimed at identifying new therapeutic targets and biomarkers to improve the diagnosis and treatment of Parkinson's disease.

I received my Biology degree, Health and Life Sciences specialization, in 2003 at the Universitat Pompeu Fabra (Barcelona, Spain). I got my Ph.D. in 2008 in the laboratory of Dr. Mariona Arbonés at the Center for Genomic Regulation (CRG, Barcelona, Spain). My Ph.D. was devoted to study the molecular basis of Down Syndrome neurological alterations. In 2009, I joined the group of Professor Thomas Perlmann at the Ludwig Institute for Cancer Research – Karolinska Institutet (Stockholm, Sweden) as a post-doctoral Marie Curie researcher to work on the transcriptional regulation of dopamine neurons during development and in pathological conditions such as Parkinson’s disease.

In 2014, I moved back to Barcelona and joined the Neurodegenerative Diseases Research Group at the Vall d’Hebron Research Institute (VHIR) as a Beatriu de Pinós post-doctoral researcher funded by AGAUR-FP7 Marie Curie Actions. Afterwards, I received a Young Investigator contract from the Spanish government (Ministry of Economy and Competitiveness (MINECO)) and a Junior Leader fellowship from the La Caixa Foundation to establish my own research lines within the group. In addition, I am an associate researcher at the Neuroscience Institute of the Autonomous University of Barcelona (UAB) and Scientific Ambassador of the World Parkinson Coalition.

The research from my team is devoted to elucidate the molecular mechanisms of inter-organ communication in Parkinson’s disease and how this contributes to the pathophysiology and symptoms of this neurodegenerative disorder. Our research contributes to: (i) identify biomarkers for early detection, disease progression or response to treatment, (ii) identify new molecular targets and develop novel therapeutic strategies with disease-modifying potential, (iii) unravel molecular pathways common to other neurodegenerative or metabolic diseases. Researcher ID: F-9561-2016; Orcid: 0000-0002-9732-6677.

Projects

diVHulga. Programa anual de actividades UCC+I del Campus Vall d’Hebron (VH)

IP: Immaculada Hernández Rodríguez
Collaborators: Josep Quer Sivila, Sara Ruiz Gallardo, Julia Basallote Garciade Quiros, Beatriz Blasco Perez, Ariadna Laguna Tuset, Diana Fernandes de Rafael
Funding agency: Fundación Española Ciencia y Tecnología (FECYT)
Funding: 30000
Reference: FCT-23-19812
Duration: 01/07/2024 - 30/06/2025

Tejiendo Ciencia

IP: Ariadna Laguna Tuset
Collaborators: Anna Santamaria Margalef, Maria Mar Hernandez Guillamon, Sara Mas Assens
Funding agency: Fundación Española Ciencia y Tecnología (FECYT)
Funding: 15000
Reference: FCT-2023-19804
Duration: 01/12/2024 - 30/11/2025

The brain-body axis in Parkinson's disease for biomarker and therapeutic development (BRAIN-BODY-PD)

IP: Ariadna Laguna Tuset
Collaborators: -
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 199998.14
Reference: CNS2023-145555
Duration: 01/04/2024 - 31/03/2026

Ministerio de Ciencia

The Gut-Brain axis in Parkinson's disease: novel pathogenic mechanisms and new possibilities for biomarkers and therapeutic approaches

IP: Ariadna Laguna Tuset
Collaborators: Laia Perez Lasarte
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 74452.89
Reference: 2024 FI-1 00557
Duration: 01/05/2024 - 30/04/2025

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