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Cristina Solé Marce

I am a Senior-Junior Principal Investigator in the Rheumatology team at the Systemic Lupus Erythematosus Unit of the Vall Hebron Research Institute. Previously, I held a postdoctoral research position in the same unit, and during my PhD, I conducted research at the University of Durham (Durham, UK), Anacor Pharmaceuticals (California, USA), and Rovira i Virgili University (Tarragona, Catalonia). I hold a dual degree in Chemistry and Biochemistry, and during these studies, I also conducted research at the University of Reading (Reading, UK) and the University of the Balearic Islands (Mallorca, Spain). My research career has focused on autoimmune diseases, particularly on the pathogenesis of lupus and antiphospholipid syndrome, as well as the synthesis and mechanisms of action of biological drugs.

Institutions of which they are part

Main researcher
Rheumatology
Vall Hebron Institut de Recerca

Cristina Solé Marce

Institutions of which they are part

Main researcher
Rheumatology
Vall Hebron Institut de Recerca

I am a Senior-Junior Principal Investigator in the Rheumatology team at the Systemic Lupus Erythematosus Unit of the Vall Hebron Research Institute. Previously, I held a postdoctoral research position in the same unit, and during my PhD, I conducted research at the University of Durham (Durham, UK), Anacor Pharmaceuticals (California, USA), and Rovira i Virgili University (Tarragona, Catalonia). I hold a dual degree in Chemistry and Biochemistry, and during these studies, I also conducted research at the University of Reading (Reading, UK) and the University of the Balearic Islands (Mallorca, Spain). My research career has focused on autoimmune diseases, particularly on the pathogenesis of lupus and antiphospholipid syndrome, as well as the synthesis and mechanisms of action of biological drugs.

Since 2021, I am Senior-Junior Principal Investigator in the Rheumatology team at the Systemic Lupus Erythematosus Unit of the Vall Hebron Research Institute (VHIR). Previously, I spent six years as a postdoctoral researcher in the same unit. Since then, our focus has been on research aimed at improving patients' lives, whether through the identification of new biomarkers that inform us about their condition without the need for invasive techniques, or through the discovery of the effects of new drugs and/or the molecular pathways involved in the development of different clinical manifestations. In this regard, we have already published several papers in internationally recognized journals and have been invited to prestigious conferences (ACR, EULAR, etc.).

Before joining VHIR, I graduated with dual degrees in Chemistry and Biochemistry from Rovira i Virgili University, where I achieved the highest academic record in both programs. I then began my PhD, focusing on the enantioselective synthesis of drugs, while simultaneously completing a master’s degree in "Synthesis and Catalysis" at Rovira i Virgili University.

I have completed various research stays at national, European, and international levels. Specifically, I worked at the University of the Balearic Islands with Dr. Palou's team, researching the regulation of metabolism via ghrelin/leptin. I then conducted research at Reading University with Dr. Katja Strohfeldt, synthesizing anticancer drugs based on germanium. Additionally, I worked at Durham University with Dr. Andy Whiting, exploring new enantio- and diastereo-selective pathways for drug synthesis. Finally, before joining my current team, I worked at Anacor Pharmaceuticals in Palo Alto (California, USA), both in the chemical synthesis and biological departments.

Projects

Teràpia gènica amb miRNAs d'interferència com a nova alternativa de tractament al lupus eritematós discoide (LED)

IP: Cristina Solé Marce
Collaborators: -
Funding agency: Institut d'Estudis Catalans (IEC)
Funding: 6000
Reference: IEC/PREMI/2022/SOLE
Duration: 01/04/2023 - 31/12/2024

Novel therapeutic topical approach for discoid lupus cutaneous (DLE) treatment

IP: Cristina Solé Marce
Collaborators: Berta Ferrer Fábrega, Gloria Aparicio Español
Funding agency: Instituto de Salud Carlos III
Funding: 99099
Reference: PI21/01869
Duration: 01/01/2022 - 31/12/2025

Las células T del receotir del autoantígeno quimérico (CAAR-Tcell) como nueva terapia dirigida para la nefritis lúpica.

IP: Josefina Cortes Hernandez
Collaborators: José Ordi Ros, Cristina Solé Marce
Funding agency: Instituto de Salud Carlos III
Funding: 122815
Reference: PI18/01917
Duration: 01/01/2019 - 30/06/2023

Investigación del mecanismo de acción de la Talidomida en el Lupus Discoide para el desarrollo de nuevas terapias

IP: Josefina Cortes Hernandez
Collaborators: Jordi Mollet Sánchez, Cristina Solé Marce
Funding agency: Instituto de Salud Carlos III
Funding: 104665
Reference: PI15/02145
Duration: 01/01/2016 - 31/12/2019

Related news

The head of the Rheumatology Service at Vall d'Hebron University Hospital and of the Rheumatology research group at VHIR is a highly accomplished rheumatologist with a distinguished career in the field.

It is the first international multi-centre clinical trial to analyse the safety and effect of this treatment for an autoimmune disease.

Els estudis avançaran en els camps de les malalties digestives, el VIH, la fatiga crònica, les patologies cardíaques, l’hepatitis, la diabetis i l’oftalmologia.

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