Josep Castellví Vives Institutions of which they are part Translational Molecular Pathology Vall Hebron Institut de Recerca Email Josep Castellví Vives Email Institutions of which they are part Translational Molecular Pathology Vall Hebron Institut de Recerca
Research lines Study of CAP-dependent and CAP-independent signalling pathways in breast carcinomas. In previous works we studied several factors involved in cell signalling pathways that control cell growth. The found that the phosphorylated form of 4E-BP1 was the only factor that correlated with prognosis, and histologic aggressive features in several types of cancers. 4E-BP1 is a key regulator of CAP-dependent traslation and its main function is the inactivation of eIF4E. However, not all the aggressive tumors show activation of this factor. On the other hand, it has been shown that under hypoxia conditions cells the translation of some key factors can be regulated by CAP-independent pathways, mediated by factors known as ITAFs. The aim of our study is to find the CAP-depdendent/CAP-independent balance in tumors in relation to hypoxia, and evaluate its impact on prognosis. IP: Josep Castellví Vives Projects Establecimiento de una estrategia combinada en carcinoma escamoso de cabeza y cuello (HNSCC): una herramienta eficaz para superar los tumores quimiorresistentes. IP: Matilde Lleonart Pajarin Collaborators: Yoelsis Garcia Mayea, Juan Lorente Guerrero, Josep Castellví Vives, Marina Bataller Fernández, Pablo Sanchez Sancho, Almudena Sanchez Garcia, Juan Fernando Fuentes Cabrera, Juan Fernando Fuentes Cabrera Funding agency: Instituto de Salud Carlos III Funding: 240000 Reference: PI24/00630 Duration: 01/01/2025 - 31/12/2027 NANORESCAN IP: Matilde Lleonart Pajarin Collaborators: David Virós Porcuna, Josep Castellví Vives, Marina Bataller Fernández, Almudena Sanchez Garcia, Juan Fernando Fuentes Cabrera, Juan Fernando Fuentes Cabrera Funding agency: Instituto de Salud Carlos III Funding: 318750 Reference: AC24/00057 Duration: 01/01/2025 - 31/12/2027 Precision Endometriosis Research: Integrating Molecular Classification, In Vitro Modeling, and Personalized Therapeutic Strategies IP: Eva Colas Ortega Collaborators: Elena Suarez Salvador, Francesc Xavier Serra Marin, Carina Masferrer Ferragutcasas, Anna Ruano Lopez, Josep Castellví Vives, Sonia Monreal Clua, Raquel Delgado Gil Funding agency: Fundació La Marató de TV3 Funding: 200000 Reference: 202407-10 Duration: 20/02/2025 - 19/02/2028 ScreenEC, validació d'una eina de triatge no invasiu en càncer d'endometri IP: Eva Colas Ortega Collaborators: Vicente Bebia Conesa, Francesc Xavier Serra Marin, Josep Castellví Vives, Silvia Cabrera Diaz, Antonio Gil Moreno, Marta Rebull Santamaria, Ana Luzarraga Aznar, Irene De la Calle Fuentes, Lourdes Elena Salazar Huayna, Lourdes Elena Salazar Huayna Funding agency: Generalitat de Catalunya - Departament de Salut Funding: 99946 Reference: SLT036/24/000059 Duration: 21/12/2024 - 20/12/2025 Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 … Next page › Last page »
