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Manuel Comabella Lopez

Dr. Manuel Comabella earned his medical degree at the University of Barcelona, completed his neurology residency at the Neurology Department of the Hospital Universitari Vall d’Hebron (HUVH), and earned his PhD at the Universitat Autònoma de Barcelona. Since 2004, Dr. Manuel Comabella is the Head of the Clinical Neuroimmunology laboratory at the Fundació Institut de Recerca del HUVH. Since June 2008 he works as a clinical neurologist at the Department of Neurology / Neuroimmunology of the MS Centre of Catalonia (Cemcat), HUVH, Barcelona.

Institutions of which they are part

Main researcher
Clinical Neuroimmunology
Vall Hebron Institut de Recerca
Responsable Laboratori
Multiple Sclerosis Centre of Catalonia

Manuel Comabella Lopez

Institutions of which they are part

Main researcher
Clinical Neuroimmunology
Vall Hebron Institut de Recerca
Responsable Laboratori
Multiple Sclerosis Centre of Catalonia

Dr. Manuel Comabella earned his medical degree at the University of Barcelona, completed his neurology residency at the Neurology Department of the Hospital Universitari Vall d’Hebron (HUVH), and earned his PhD at the Universitat Autònoma de Barcelona. Since 2004, Dr. Manuel Comabella is the Head of the Clinical Neuroimmunology laboratory at the Fundació Institut de Recerca del HUVH. Since June 2008 he works as a clinical neurologist at the Department of Neurology / Neuroimmunology of the MS Centre of Catalonia (Cemcat), HUVH, Barcelona.

From 1996 to 1998, Dr. Manuel Comabella was a Research Fellow in Neuroimmunology at the Center for Neurologic Diseases, Brigham and Women´s Hospital, in Boston. In 2010 was awarded with the Ayudas Merck Serono in the multiple sclerosis research area. In 2011 was awarded by the Spanish Society of Neurology (SEN) with the Biogen Idec Prize to the best publication on demyelinating disorders. In 2013 was awarded by the SEN with the Novartis Prize to the best oral communication and the best publication on demyelinating disorders. In 2014 received the Neurological Disorders Award, scientific modality, granted by the SEN. In 2016 was awarded with the Ayudas Merck Serono in the multiple sclerosis research area. From 2018 to 2020, Dr. Manuel Comabella was a collaborator of the Biomedicine area at the Division of Coordination, Evaluation and Scientific and Technical Follow-up of the State Research Agency, Ministry of Science, Innovation and Universities.

Dr. Manuel Comabella is member of the Editorial Board of Journal of Neuroimmunology and Multiple Sclerosis Journal, member of the Board of the ESNI (European School of Neuroimmunology), and member of the Strategic Group of the IMSGC (International Multiple Sclerosis Genetics Consortium). He is coauthor of 297 documents indexed in MedLine (Scopus: 12916 total citations, with h-index of 54). Dr. Manuel Comabella's research interest lies in the identification of biomarkers related with different aspects of multiple sclerosis and the development of new therapeutic strategies for the disease.

Projects

Neuroimmunologia Clínica. Centre d'Esclerosi Múltiple de Catalunya (CEMCAT( (GRC)

IP: Neuroimmunologia Clínica. Centre d'Esclerosi Múltiple de Catalunya (CEMCAT( (GRC)
Collaborators: Susana Otero Romero, Carlos Nos Llopis, Neuroimmunologia Clínica. Centre d'Esclerosi Múltiple de Catalunya (CEMCAT( (GRC), José Ant. Graells Salvador, Jaume Sastre Garriga, Jordi Rio Izquierdo, Ingrid Galán Cartaña, Rosalia Horno Ocaña, Manuel Comabella Lopez, Margarida Capell Maymo, Carmen Tur Gomez, Neuroimmunologia Clínica. Centre d'Esclerosi Múltiple de Catalunya (CEMCAT( (GRC), Herena Eixarch Ahufinger, Carme Santoyo Medina, Oriol Nualart Mundo, Neuroimmunologia Clínica. Centre d'Esclerosi Múltiple de Catalunya (CEMCAT( (GRC), M Jesus Arevalo Navines, Dunia Muñoz Valdivielso, Carmen Espejo Ruiz, Silvia Casacuberta Serra, Sergio Vergara Ruiz, Luciana Midaglia Fernandez, Joaquin Castillo Justribo, Milagros Fraga Pereira, Breogan Rodriguez Acevedo, Mireia Castillo Juarez, Nicolás Miguel Fissolo , Georgina Arrambide García
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 50000
Reference: 2014 SGR 1082
Duration: 01/01/2014 - 31/12/2016

Search of biomarkers in patients with progressive multiple sclerosis

IP: -
Collaborators: Manuel Comabella Lopez
Funding agency: National Multiple Sclerosis Society
Funding: 74250
Reference: MSBIOMARKERS_NATMSALLIANCE2014
Duration: 01/08/2014 - 30/11/2015

Estudio de expresión del gen HLA-DRB1 en pacientes con esclerosis múltiple positivos y negativos para el alelo HLA-DRB1*15:01

IP: Manuel Comabella Lopez
Collaborators: -
Funding agency: Fundación Genzyme
Funding: 10000
Reference: GENZYMEEN-2013-01
Duration: 23/12/2013 - 30/09/2015

Biological markers for rationalizing treatment decisions in Multiple Sclerosis (BEST-MS) Grand Agreement nº 305477

IP: Manuel Comabella Lopez
Collaborators: Jordi Rio Izquierdo
Funding agency: EUROPEAN COMMISSION
Funding: 424320
Reference: BEST-MS_FP7HEALTH2012
Duration: 01/11/2012 - 31/10/2016

Related news

An international study led by researchers from Vall d’Hebron shows that simple tests that patients can perform themselves help detect changes in disability that may occur even in the absence of disease relapses.

A Vall d’Hebron study, carried out at Cemcat, shows that the risk of inflammatory activity increases after discontinuing treatment, but is considerably reduced in people over 60 years of age.

The project will analyse the functional activation of the NLRP3 inflammasome to advance the early identification of patients at risk of insufficient response to S1P receptor-modulating therapies.

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