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Maria Jose Pérez García

I am a senior researcher at the Vall d'Hebron Research Institute (VHIR). In addition to my research work, for the past decade, I have served as a coordinator and professor in the Master's in Translational Biomedical Research at VHIR.

Institutions of which they are part

Main researcher
Childhood Cancer and Blood Disorders
Vall Hebron Institut de Recerca
Biòloga
Paediatric Oncology and Haematology
Children's Hospital and Woman's Hospital

Maria Jose Pérez García

Institutions of which they are part

Main researcher
Childhood Cancer and Blood Disorders
Vall Hebron Institut de Recerca
Biòloga
Paediatric Oncology and Haematology
Children's Hospital and Woman's Hospital

I am a senior researcher at the Vall d'Hebron Research Institute (VHIR). In addition to my research work, for the past decade, I have served as a coordinator and professor in the Master's in Translational Biomedical Research at VHIR.

I graduated in Biochemistry from the University of the Balearic Islands (UIB) in 2000. During my predoctoral research, I focused on studying the mechanisms regulating the survival and death of motor neurons following neurotrophic factor withdrawal, as well as the crucial role of calcium in this process. Additionally, I undertook predoctoral stays both in Spain, at the University of Castilla-La Mancha, and abroad, at INSERM U.382 in Marseille, which expanded my perspective and experience in the research field.

After obtaining my doctorate, I continued my research career with a postdoctoral fellowship at Columbia University (USA), under the supervision of Dr. A.H. Kottmann, focusing on the study of amyotrophic lateral sclerosis (ALS). Subsequently, I joined Dr. Steve J. Burden's group at New York University (NYU), where I participated in projects related to fibroblast differentiation into myoblasts induced by MyoD expression, as well as in the analysis of MuSK receptor overexpression in a murine model of neuromuscular pathology.

In 2012, I joined Dr. Francina Munell's group in the field of Pediatric Neurology, through the Beatriz de Pinós program, conducting a project related to neuromuscular junctions in spinal muscular atrophy. Later, I joined the cell signaling and apoptosis group, led by Dr. Joan X Comella, where I supervised several projects and directed various doctoral theses. Currently, I am a senior researcher in the Pediatric Oncology group.

In addition to my research activities, I am actively involved in training postgraduate students as a teacher and coordinator of the Diseases of the Nervous System module in the Master's in Translational Biomedical Research at VHIR since 2014.

Projects

Development of prognostic and therapeutic tools targeting epigenetic regulators in metastatic neuroblastoma

IP: Miguel Segura Ginard
Collaborators: María Rosario Pérez- Torres Lobato, Maria Jose Pérez García, Lorena Valero Arrese, Ariadna Boloix Amenós, Adria Molero Valenzuela, Khloud Abdo Soliman Elsharawy
Funding agency: Instituto de Salud Carlos III
Funding: 315000
Reference: PI23/01144
Duration: 01/01/2024 - 31/12/2026

MONALISA: A SIOPEN pragmatic clinical trial to MOnitor NeuroblastomA relapse with LIquid biopsy Sensitive Analysis

IP: Lucas Moreno Martín-Retortillo
Collaborators: Maria Jose Pérez García, Miguel Segura Ginard
Funding agency: EUROPEAN COMMISSION
Funding: 8000
Reference: MONALISA_HE-MISS2023
Duration: 01/01/2024

TACTIC: Explorando soluciones a los retos de salud mediante ciencia disruptiva, terapias avanzadas y medicina de sistemas

IP: Begoña Benito Villabriga
Collaborators: Carmen Escudero Iriarte, Laia Ventura i Expósito, Susana Otero Romero, Ibane Abasolo Olaortua, Ignacio Ferreira González, José Antonio Barrabés Riu, Carlos Nos Llopis, Pablo Velasco Puyó, Jose Fernando Rodríguez Palomares, María Rosario Pérez- Torres Lobato, Sunny Malhotra Sareen, Perez Dueñas, Belen, Jaume Sastre Garriga, Joan López Hellin, Antonia Sambola Ayala, Jordi Rio Izquierdo, Nuria Rivas Gandara, Jordi Perez Rodon, Aroa Soriano Fernández, Manuel Comabella Lopez, Antonio Rodríguez Sinovas, Gisela Teixido Tura, Antonia Pijuan Domenech, Roser Ferrer Costa, Joaquin Seras Franzoso, Carmen Tur Gomez, Maria Cristina Díaz de Heredia Rubio, Laia Yañez Bisbe, Julia German Cortes, Maria Jose Pérez García, Miguel Segura Ginard, Diego Baranda Martínez-Abasca, Cristina Auger Acosta, Neus Bellera Gotarda, Herena Eixarch Ahufinger, M Mar Mañu Pereira, Deborah Pareto Onghena, Lorena Valero Arrese, Aitor Uribarri Gonzalez, Jordi Bañeras Rius, Alex Rovira Cañellas, Mar Tintore Subirana, Bruno García del Blanco, Maria Teresa Salcedo Allende, Marisol Ruiz Meana, Ana Belén Méndez Fernández, Xavier Montalban Gairín, Simon Schwartz Navarro, Anna Llort Sales, Carmen Espejo Ruiz, Raquel Hladun Alvaro, Angels Alcina Mila, Sandra Mancilla Zamora, Zamira Vanessa Diaz Riascos, Ana Zabalza de Torres, Ariadna Boloix Amenós, Marc Miquel Moltó Abad, Javier Inserte Igual, Elizabeth Pando Rau, Gabriela Guillén Burrieza, Cazurro Gutierrez, Ana Laura, Gómez Andrés, David, Alvaro Cobo Calvo, Alvaro Calabuig Goena, Joaquin Castillo Justribo, Lydia Dux-Santoy Hurtado, Lucas Moreno Martín-Retortillo, Andres Miguez Gonzalez, Josep Roma Castanyer, Laura Dos Subirá, Nicolás Miguel Fissolo, Maria Nazarena Pizzi, Tian Tian, Fernanda Raquel Da Silva Andrade, Diana Fernandes de Rafael, Andrea Guala
Funding agency: Instituto de Salud Carlos III
Funding: 2494527.53
Reference: FORT23/00034
Duration: 01/01/2024 - 31/12/2027

Grup de Recerca Emergent (GRE) Childood Cancer & Blood disorders

IP: Lucas Moreno Martín-Retortillo
Collaborators: Luís Gros Subias, Raquel Andreu Vilarroig, Andrea Vilaplana Blanes, Pablo Velasco Puyó, Laura Murillo Sanjuán, Maria Isabel Benitez Carabante, Aroa Soriano Fernández, Guillem Pons Barcons, Jose Miguel Lizcano De Vega, Maria Cristina Díaz de Heredia Rubio, María de los Ángeles Rodríguez Sánchez, Grup de Recerca Emergent (GRE) Childood Cancer & Blood disorders, Maria Jose Pérez García, Miguel Segura Ginard, M Mar Mañu Pereira, Lorena Valero Arrese, Thaïs Murciano Carrillo, Constantino Sábado Álvarez, Anna Llort Sales, Elisabet Megías Roda, Raquel Hladun Alvaro, Ariadna Boloix Amenós, Carlota Aguilera Ordoñez, Adria Molero Valenzuela, Júlia Sansa Girona, Gabriela Guillén Burrieza, Laura Alonso Garcia, Victoria Gutierrez Valle, Idoia Bolinaga Ayala, Josep Roma Castanyer, Sergio Espinosa Gil, Elena Andretta, Claire Diot, Amira Idrizovic
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 60000
Reference: 2021 SGR 00638
Duration: 01/01/2022 - 30/06/2025

Related news

"Generation of a bank of surgical orthotopic PDX (patient-derived xenografts) models within the framework of a personalized medicine program in pediatric cancer" was the awarded work, of the Childhood Cancer and Hematological Diseases Group of VHIR.

A study, co-led by Vall d’Hebron, has analysed the evolution of clinical trials with children and adolescents with cancer over the last 15 years, with the aim of optimising efficacy and defining lines for further progress.

The research team has shown that inhibiting the TRIB3 protein slows the growth of rhabdomyosarcoma and improves survival in animal models.

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