Santiago Ramon y Cajal Agüeras Institutions of which they are part Head of group Translational Molecular Pathology Vall Hebron Institut de Recerca Email Santiago Ramon y Cajal Agüeras Email Institutions of which they are part Head of group Translational Molecular Pathology Vall Hebron Institut de Recerca
Research lines Study of Cell Signalling pathway in human tumors. Identification of funnel factors. We have characterized the levels of activation in Cell Signalling in a spectrum of solid tumors and correlated the levels of various factors, including mTOR and downstream proteins (p70S6K, S6, 4EBP1, eIF4E) with prognosis and grade of malignancy. Also, are being characterized, at the molecular level, the factors involved in controlling the translation cap dependent and independent in malignant tumors. IP: Santiago Ramon y Cajal Agüeras Study of gene expression of senescence in human tumors The expression of mARN genes identified by Dr.R. Bernards has been studied in normal and tumor tissue of cancer patients. This study identifies for the first time, RSK4 and KIAA0828 genes as genes whose role may be relevant in cancer. The expression of these genes is being studied in protein by Western blot and immunohistochemistry. Also are characterizing the biochemical pathways where these genes may be involved. IP: Santiago Ramon y Cajal Agüeras Identification of molecular targets associated with tumor progression and therapy resistance in colorectal carcinoma. Studying in colorectal cancer mechanisms of action of the central signal transduction pathways, identify potential molecular alterations that can be used as therapeutic targets and characterize the degree of genetic inestability. IP: Santiago Ramon y Cajal Agüeras Projects CancerScan: Smart pathology slide scanner for diagnosis and patient-specific treatment recommendation in oncology IP: Santiago Ramon y Cajal Agüeras Collaborators: - Funding agency: EUROPEAN COMMISSION Funding: 609600 Reference: EC/PATHFINDER_OPEN/2024/RAMON_Y_CAJAL Duration: 01/08/2025 - 31/07/2028 CancerScan: Smart pathology slide scanner for diagnosis and patient-specific treatment recommendation in oncology IP: Santiago Ramon y Cajal Agüeras Collaborators: Joaquin Seras Franzoso, Diego Baranda Martínez-Abasca, Diego Baranda Martínez-Abasca, Sandra Mancilla Zamora, Marc Miquel Moltó Abad, Gisela Espriu Aguado, Sonia Borao Arriazu Funding agency: EUROPEAN COMMISSION Funding: 609600 Reference: CANCERSCAN_RAMON Y CAJAL_EC/PATHFINDER_OPEN2024 Duration: 01/08/2025 - 31/07/2028 MNK - EB1 IP: Santiago Ramon y Cajal Agüeras Collaborators: Inés de Torres Ramirez, Adriana Martinez Cifuentes, Sara Garcia Ortega, Elena Muro Blanc, Marta Cano Galietero, Vicente Peg Camara, Stefan Hummer Funding agency: Generalitat de Catalunya - Departament de Salut Funding: 189970 Reference: SLT036/24/000026 Duration: 21/12/2024 - 20/12/2026 Synthetic Data Generation Framework for Integrated Validation of Use Cases and AI Healthcare Applications IP: Manuel Escobar Amores Collaborators: Santiago Ramon y Cajal Agüeras, Aitor Rodriguez Martinez, Javier Hernandez Losa, Sonia Borao Arriazu Funding agency: EUROPEAN COMMISSION Funding: 163125 Reference: SYNTHIA_M.ESCOBAR_HE-JU-IHI_2023 Duration: 01/09/2024 - 31/08/2029 Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 … Next page › Last page »
