Catalogue of animal models from Vall d'Hebron Barcelona Hospital Campus Use the search engine to find the models you need for your research. Animal species - None -Mice (Mus musculus)Pig (Sus scrofa)Mice (Muss musculus); Rat (Rattus norvegicus)Rat (Rattus norvegicus)Mice (Mus-musculus); NOD SCID gammaSheep (Ovis Linnaeus) Thematic area - None -OrthopedicNeuroscienceOncologyOncology, Rare diseaseLiver DiseasesImmunologyDiseases of the sense organs (skin, eyes and ears)Metabolic diseasesType 2 Diabetes; Type 1 DiabetesMusculoskeletal diseasesNeuroimmunologyDiseases of the sense organs (skin, eyes and ears)/DiabetesNeurovascular diseasesRare diseasesEndocrinologyInflammationNephrology Physiology and Pathophysiology of the Digestive TractCardiovascular diseases Neuroscience, Rare diseases Specific pathology - None -Colorectal CancerEndometrial cancerOvarian cancerSarcomaEndometrial cancer; Ovarian cancerMetastasis of glioblastoma, brain, bone, uterine cervix, endometrial and nasopharyngeal cancerLung cancer, glioblastoma and skin cancerCholangiocarcinoma, gastric cancerBreast cancerCancerDisorders of body’s energy balance; Obesity; Type 2 diabetesPhysiological cardiac remodellingMyocardium infarctHeart failureParkinson's disease; neuromelanin productionGlioblastomaProstate cancer and bone metastasisColorectal cancerLung cancerNeuroblastomaOncology & Immuno-OncologyGlioblastoma, breast, colorectal, prostate and pancreatic cancerParkinson's disease; mutant GBA gene carrying D409V mutationParkinson's disease; mutant GBA gene carrying L444P mutationParkinson's diseasePortal Hypertension Type 2 Diabetes; Type 1 DiabetesProstate cancer Colon cancerMelanomaPancreatic ductal adenocarcinoma (PDAC)Small intestinal tumors and Colorectal cancer Metastasis of prostate cancerOncology & Inmuno Oncology, pharmacologyDifferent type of human cancers, including colorectal, breast, prostate, brain, lung and pancreatic, Ewing's sarcoma, glioblastomaPancreatic, lung, colon cancer and glioblastomRight heart failurePigmentary retinosisHepatic cirrhosisSkin Cancer; melanomaCerebral ischemiaHepatocellular CarcinomaPancreatic cancer Alzheimer Renal toxicity GlaucomaDiabetic Macular EdemaAge-related macular degenerationMultiple SclerosisRetinal neurodegeneration and microvascular abnormalities; diabetic macular edemaCardiac IschemiaCardiac deletion of Cx43: arrhythmias and sudden death (50% after 14 days of induction)Renal ischemia Air pollutionAneurysmAlzheimer and Sporadic Cerebral Amyloid AngiopathyBone regenerationCardiac Ischemia, reperfussionIschemia/reperfussionRenal fibrosisFabry disease; lysosomal storage disordersMultiple myelomaCancer models: human, mouse and syngeneic; melanomaTransplant rejectionTransplant rejection and immuno-modulationSepsisInsulin Resistance; Type 2 diabetes mellitusOncology & Inmuno oncologyMuscle pathologySteatohepatitis with fibrosis and portal hypertension Steatohepatitis with portal hypertension (NO fibrosis)MigraineCartilage InjuryGlaucoma (retinal neurodegeneration)Malignant infarction of the middle cerebral arteryLung cancer, Lymphoma; Multiple MyelomaHypertensionDigestive, autoinmunology; ulcerative colitisCirrhosis; NASH; healthy ratsExperimental model of Irritable Bowel syndrome; intestinal barrier dysfunctionGNB1 EncephalopathyWet age-related macular degeneration; diabetic retinopathyLymphomaOncology & Immuno-Oncology; melanomaSpina bifida Animal model name - None -Orthotopic models derived from Colorectal Organoid models modified with FmC (lentivirus luciferase and mCherry) from Msh2loxP/vCre/Braf mouse model Patient-derived Orthotopic Xenograft (PDXO) models of Endometrial CancerPDX model of Ovarian Cancer cells PDX model of SarcomaPDX models of Endometrial and Ovarian Cancers PDX models of Glioblastoma, Brain, Bone, Uterine cervix, Endometrial and Nasopharyngeal MetastasisPDX models of Lung, Glioblastoma and Skin CancerPDX of Cholangiocarcinoma and Gastric CancerPDX Orthotopic Xenograft of Breast CancerPDX Orthotopic Xenograft of Cancer cellsPGC1alpha/beta-FAT-DKOPGC-1alpha-FAT-KO PGC1-beta-FAT-KOPhysiologycal Cardiac Remodeling mouse modelPorcine model of Myocardium Infarct-closed thoraxPorcine model of Myocardium Infarct-open thoraxPathological Cardiac Remodelling induced by pressure overloadParkinson's disease modelOrthotopic Xenograft model of Breast Cancer Orthotopic Xenograft model of Breast Cancer and Pancreatic CancerOrthotopic Xenograft model of Glioblastoma Orthotopic Xenograft model of Prostate Cancer Orthotopic Xenograft of Breast Cancer Orthotopic Xenograft of Colorectal CancerOrthotopic Xenograft of GlioblastomaOrthotopic Xenograft of Lung CancerOrthotopic Xenograft of NeuroblastomaOrthotopic Xenograft of Ovarian Cancer cells (disseminated model)Orthotopic Xenograft of Ovarian Cancer cells and Ascitic cells Orthotopic Xenografts models of Human Cancer cell lines and PDXParkinson and Gaucher modelPortal Hypertention by portal vein ligation modelPpargc1a flox/floxPpargc1b flox/floxSubcutaneous Xenografts of prostate Cancer cell linesSubcutanous Xenograft model of Colon CancerSubcutanous Xenograft model of MelanomaSubcutanous Xenograft of Colorectal CancerSubcutanous Xenograft of GlioblastomaSubcutanous Xenograft of NeuroblastomaSubcutanous Xenograft of Pancreatic CancerSyngeneic models derived from Intestinal and Colorectal Organoid models from Msh2loxP/vCre mouse model Syngeneic models derived from Intestinal and Colorectal Organoid models from Msh2loxP/vCre/Braf mouse model Syngeneic models derived from Intestinal Organoid models from vCre/Braf mouse model Syngeneic Orthotopic or intravenous model of Lung CancervCre/BrafXenograft model of metastasis Prostate CancerXenograft model of Ovarian CancerXenograft model of pharynx and Larynx CancerSubcutaneous Xenografts of human Cancer cell lines and PDXSubcutaneous Xenograft Tumor modelSubcutaneous Xenograft of MelanomaPrimary tumor of SarcomaRat model of transient Coronary OcclusionRight Heart Failure mouse modelRoyal College of Surgeons (RCS) rat model of Retinal DegenerationSecondary Cholestasis due to bile duct ligation (BDL) modelSpontaneous murine model of Skin Cancer induced by UV radiationStroke modelSubcutaneous and Orthotopic Xenograft murine models of Endometrial and Ovarian Cancer using commercial cell linesSubcutaneous Xenograft model of Hepatocellular Carcinoma Subcutaneous Xenograft models of Pancreatic Cancer in inmunodeficient mouseSubcutaneous Xenograft of Cholangiocarcinoma and Gastric CancerSubcutaneous Xenograft of Lung CancerXenograft model of Pharynx and Larynx CancerOrthotopic models derived from Colorectal Organoid models modified with FmC (lentivirus luciferase and mCherry) from Msh2loxP/vCre mouse model 5xFAD model Alzheimer Cyclosporine (CsA)-induced Renal Toxicity modelDexamethasone-induced GlaucomaDiabetic rats by injection with streptozotocin (STZ)DIO (diet-induced obesity)Drug-induced pathological Cardiac Remodelling mouse modelDry macular degeneration murine model EAE - Experimental Autoimmune Encephalomyelitis - Chronic model EAE - Experimental Autoimmune Encephalomyelitis - Chronic progressive modelEAE - Experimental Autoimmune Encephalomyelitis - Relapsing-remitting modelEarly non-proliferative Diabetic Retinopathy Ectopic xenograft model of Neuroblastoma Ex vivo Cardiac Ischemia mouse modelEx vivo Cardiac Ischemia rat modelCx43-deficiency in mice induced by 4-hydroxytamoxifen intraperitoneal administrationChronic Liver Disease induced by intraperitoneal injection of thioacetamide (TAA)Chronic Liver Disease induced by inhalation of carbon tetrachloride (CCl4)Acute Cold exposureAcute Kidney Injury and regeneration modelAir Pollution rat modelAneurysm modelAPP23 model Alzheimer Cerebral Beta-amyloidosis Bone Defects in metaphysis (cylindrical)Caloric RestrictionCancer modelsCardiac Ischemia mouse modelCardiac Ischemia pig modelCardiac Ischemia rat modelCardiac Ischemia-Reperfussion mouse modelCardiac Ischemia-Reperfussion pig modelCardiac Ischemia-Reperfussion rat modelChronic Kidney disease (CKD) modelEx vivo cardiac Ischemia-Reperfussion mouse modelEx vivo cardiac Ischemia-Reperfussion rat modelFabry modelMsh2loxP/vCre/BrafMultiple Myeloma disseminated mice modelMurine model of Melanoma Murine model of Allloimmune Response Activation in Kidney TransplantsMurine model of Alloimmune Response Activation and Immune Reconstitution with allogeneic and autologous bone marrow transplantsMurine model of Alloimmune Response Activation in Heart TransplantsMurine model of SepsisMurine model of Transient Coronary OcclusionMurine model of Type 2 Diabetes (insulin resistance)Murine models of Glioblastoma, Lung and Prostate tumorMuscle Injuries modelNon-Alcoholic Steatohepatitis with fibrosis and portal Hypertension (NASH model)Non-Alcoholic Steatohepatitis with portal Hypertension and NASH without fibrosis (NASH model)NR1F3-FAT-KOMsh2loxP/vCreMigraine model and its chronificationMetastatic model of Neuroblastoma Focal Articular Cartilage Knee Defects Glaucoma (retinal neurodegeneration) genetic modelGyrencephalic porcine animal model of Malignant Infarction of the middle cerebral artery Humanized mice PBMCHypertension model Inflamatory Bowel Disease (humanized and non-humanized)Intestinal Decontamination and Microbiota TransplantIrritable Bowel Syndrome in ratsTransgenic de novo animal model Laser-induced Choroidal Neovascularization model (CNV)Lung colonization of Breast cancerLymphoma disseminated mice modelMelanoma Cancer modelMetastatic model of SarcomaOpen Spinal Neural tube defects in sheep fetuses Reference Name Animal specie Strain Thematic area Specific pathology Description AT085 Spontaneous murine model of Skin Cancer induced by UV radiation Mice (Mus musculus) Oncology Skin Cancer; melanoma Neonatal mice between two and five days of age are exposed to a UVB irradiation dose of 9 KJ/m2 AT156 Stroke model Mice (Mus musculus) C57BL/6, BALB/C Neurovascular diseases Cerebral ischemia Transient or permanent proximal occlusion of middle cerebral artery by nylon filament is conducted, through the external carotid artery. Biodistribution of some treatments is monitored in vivo and ex vivo over time with molecular imaging. Functional (grip strength test) and neurological status of the animals are evaluated AT157 Stroke model Rat (Rattus norvegicus) Wistar Neurovascular diseases Cerebral ischemia Transient or permanent proximal occlusion of middle cerebral artery by nylon filament is conducted, through the external carotid artery. Biodistribution of some treatments is monitored in vivo and ex vivo over time with molecular imaging. Functional (grip strength test) and neurological status of the animals are evaluated AT158 Stroke model Rat (Rattus norvegicus) Wistar Neurovascular diseases Cerebral ischemia Transient or permanent proximal occlusion of middle cerebral artery by blood clot insertion, through the external carotid artery. t-PA-induced thrombolysis could be induced. Biodistribution of some treatments is monitored in vivo and ex vivo over time with molecular imaging. Functional (grip strength test) and neurological status of the animals are evaluated AT159 Stroke model Mice (Mus musculus) C57BL/6, BALB/C Neurovascular diseases Cerebral ischemia Transient or permanent occlusion of the distal portion of the middle cerebral artery in conducted with a 30G rounded tip needle above the artery held with a micromanipulator (with electrocoagulation for the permanent model). The biodistribution of some treatments is monitored in vivo and ex vivo over time with molecular imaging.Functional (grip strength test) and neurological status of the animals are evaluated AT086 Subcutaneous and Orthotopic Xenograft murine models of Endometrial and Ovarian Cancer using commercial cell lines Mice (Mus musculus) Swiss Nude Oncology Endometrial cancer; Ovarian cancer Orthotopic intrauterine tumor cells injection or subcutaneous injection of commercial cell lines of endometrial and/or ovarian cancer AT087 Subcutaneous Xenograft model of Hepatocellular Carcinoma Mice (Mus musculus) Swiss Nude Liver Diseases Hepatocellular Carcinoma Injection of HuH-7 cells (5x10 (6) cells) (100ul) subcutaneously in the dorsal area of the mouse AT088 Subcutaneous Xenograft models of Pancreatic Cancer in inmunodeficient mouse Mice (Mus musculus) CAnN.Cg-Foxn1nu/Crl (BALB/c nude); RjOrl:NMRI-Foxn1nu /Foxn1nu, (NMRI-nu) Oncology Pancreatic cancer The animals will receive a subcutaneous injection of pancreatic tumor cells in the right flank AT089 Subcutaneous Xenograft of Cholangiocarcinoma and Gastric Cancer Mice (Mus musculus) Nude Oncology Cholangiocarcinoma, gastric cancer Subcutaneous injection of cholangiocarcinoma cells: Hucct1, Sn1079 and gastric cancer cells: KCNMA1, SGC-7901 in mice. AT090 Subcutaneous Xenograft of Lung Cancer Mice (Mus musculus) Balbc/nu; C57BL/6; B6(Cg)-Rag2tm1.1Cgn/J; 129/Sv Oncology Lung cancer Tumor cells will be inoculated subcutaneous in the caudal dorsal flank. Pagination First page « Primera Previous page ‹ Previous … Page 3 Page 4 Page 5 Page 6 Current page 7 Page 8 Page 9 Page 10 Page 11 … Next page Next › Last page Últim » Animal samples request This catalog is updated annually. For additional information and/or to request animal models, you can contact us at catalogo.animales@vhir.org. You can also search for animal models on the ISCIII Biobanks and Biomodels Platform.
