About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.
Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.
Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours
PMID: 35130027 Journal: JOURNAL OF CLINICAL ONCOLOGY Year: 2022 Reference: J Clin Oncol. 2022 Mar 20;40(9):1030-1032. doi: 10.1200/JCO.21.02612. Epub 2022 Feb 7. Impact factor: 44.544 Publication type: Letter or abstract Authors: Defachelles, Anne-Sophie; Bogart, Emilie; Casanova, Michela; Merks, Johannes H M; Bisogno, Gianni; Calareso, Giuseppina; Melcon, Soledad Gallego; Gatz, Susanne Andrea; Le Deley, Marie-Cecile; McHugh, Kieran et al. DOI: 10.1200/JCO.21.02612
PMID: 35124293 Journal: Transplantation and cellular therapy Year: 2022 Reference: Transplant Cell Ther. 2022 May;28(5):261.e1-261.e7. doi: 10.1016/j.jtct.2022.01.025. Epub 2022 Feb 4. Impact factor: 0 Publication type: Paper in international publication Authors: Kitko, Carrie L; Abdel-Azim, Hisham; Carpenter, Paul A; Dalle, Jean-Hugues; Diaz-de-Heredia, Cristina; Gaspari, Stefania; Gennery, Andrew R; Handgretinger, Rupert; Lawitschka, Anita et al. DOI: 10.1016/j.jtct.2022.01.025
PMID: 35147457 Journal: JOURNAL OF ONCOLOGY PHARMACY PRACTICE Year: 2022 Reference: J Oncol Pharm Pract. 2022 Feb 11:10781552221079568. doi: 10.1177/10781552221079568. Impact factor: 1.809 Publication type: Paper in international publication Authors: Gros, Luis; Roldan, Alicia; Cabero-Martinez, Almudena; Dominguez-Pinilla, Nerea; Gonzalez-Barca, Eva; Tasso, Maria; Torrent, Montserrat; Gallardo, Eva; Del Cerro, Ines; Giro-Perafita, Ariadna et al. DOI: 10.1177/10781552221079568
PMID: 35152364 Journal: Clinical & Translational Oncology Year: 2022 Reference: Clin Transl Oncol. 2022 May;24(5):809-815. doi: 10.1007/s12094-021-02759-7. Epub 2022 Feb 12. Impact factor: 3.405 Publication type: Paper in international publication Authors: Canete, A; Gargallo, P; Bautista, F; Juan-Ribelles, A; Izquierdo, E; Soriano, A; de Rojas, T; Escudero, A; Lavarino, C; Solano, P et al. DOI: 10.1007/s12094-021-02759-7
PMID: 33567392 Journal: EUROPEAN JOURNAL OF CANCER Year: 2021 Reference: Eur J Cancer. 2021 Mar;146:21-29. doi: 10.1016/j.ejca.2020.12.025. Epub 2021 Feb 7. Impact factor: Publication type: Paper in international publication Authors: Arush, Myriam Weyl Ben; Bergeron, Christophe; Bergeron, Christophe; Bisogno, Gianni; Bisogno, Gianni; Cesen, Maja; Chisholm, Julia; De Corti, Federica; De Salvo, Gian Luca; Devalck, Christine et al. DOI: 10.1016/j.ejca.2020.12.025
PMID: 33534758 Journal: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Year: 2021 Reference: Am J Trop Med Hyg. 2021 Jan 18;104(3):1003-1012. doi: 10.4269/ajtmh.19-0783. Impact factor: Publication type: Paper in international publication Authors: Achtman, Ariel H; Aguilar, Ruth; Alonso, Pedro L; Aponte, John J; Macete, Eusebio; Manu Pereira, Maria Del Mar; Menendez, Clara; Moraleda, Cinta; Nhabomba, Augusto; Nhampossa, Tacilta et al. DOI: 10.4269/ajtmh.19-0783
PMID: 33205902 Journal: PEDIATRIC BLOOD & CANCER Year: 2021 Reference: Pediatr Blood Cancer. 2021 Mar;68(3):e28794. doi: 10.1002/pbc.28794. Epub 2020 Nov 18. Impact factor: Publication type: Paper in international publication Authors: Ash, Shifra; Berthold, Frank; Cohn, Susan L; Guo, Dongjing; Hogarty, Michael; Irwin, Meredith S; Kamijo, Takehiko; Ladenstein, Ruth; London, Wendy B; Moreno, Lucas et al. DOI: 10.1002/pbc.28794
PMID: 33245207 Journal: PEDIATRIC BLOOD & CANCER Year: 2021 Reference: Pediatr Blood Cancer. 2021 Mar;68(3):e28832. doi: 10.1002/pbc.28832. Epub 2020 Nov 27. Impact factor: Publication type: Paper in international publication Authors: Bisogno, Gianni; Chi, Yueh-Yun; De Salvo, Gian Luca; Gallego, Soledad; Hawkins, Douglas S; Jenney, Meriel; Li, Minjie; Mandeville, Henry; Mascarenhas, Leo; Merks, Johannes H M et al. DOI: 10.1002/pbc.28832
PMID: 31939050 Journal: CANCER AND METASTASIS REVIEWS Year: 2020 Reference: Cancer Metastasis Rev. 2020 Mar;39(1):149-160. doi: 10.1007/s10555-020-09856-z. Impact factor: Publication type: Review in international publication Authors: Bautista, Francisco; Carceller, Fernando; Darlington, Anne-Sophie; de Rojas, Teresa; Fernandez-Teijeiro, Ana; Moreno, Lucas; Neven, Anouk; Riedl, David; Sodergren, Samantha; Towbin, Alexander J et al. DOI: 10.1007/s10555-020-09856-z
PMID: 31908304 Journal: LANCET ONCOLOGY Year: 2020 Reference: Lancet Oncol. 2020 Jan;21(1):e3. doi: 10.1016/S1470-2045(19)30812-5. Impact factor: Publication type: Letter or abstract Authors: Bergeron, Christophe; Bisogno, Gianni; De Salvo, Gian Luca; Ferrari, Andrea; Jenney, Meriel; Melcon, Soledad Gallego et al. DOI: 10.1016/S1470-2045(19)30812-5
PMID: 31625177 Journal: AMERICAN JOURNAL OF HEMATOLOGY Year: 2020 Reference: Am J Hematol. 2020 Jan;95(1):28-37. doi: 10.1002/ajh.25661. Epub 2019 Nov 5. Impact factor: Publication type: Paper in international publication Authors: Alonso, Laura; Badell, Isabel; Belendez, Cristina; Benito, Ana; Bueno, David; Couselo, Jose Miguel; de Heredia, Cristina Diaz; Diaz, Miguel Angel; Diaz-Almiron, Mariana; Ferreras, Cristina et al. DOI: 10.1002/ajh.25661
PMID: 31772335 Journal: JOURNAL OF HUMAN GENETICS Year: 2020 Reference: J Hum Genet. 2020 Jan;65(2):165-174. doi: 10.1038/s10038-019-0696-z. Epub 2019 Nov 26. Impact factor: Publication type: Paper in international publication Authors: Abelairas, Jose; Alonso, Javier; Cuesta, Isabel; Fernandez-Teijeiro, Ana; Ferreres, Joan Carles; Gomez-Mariano, Gema; Gonzalez-Campora, Ricardo; Martin-Begue, Nieves; Martinez-Delgado, Beatriz; Monzon, Sara et al. DOI: 10.1038/s10038-019-0696-z
PMID: 30733543 Journal: BONE MARROW TRANSPLANTATION Year: 2019 Reference: Bone Marrow Transplant. 2019 Jul;54(7):1176. doi: 10.1038/s41409-019-0471-y. Impact factor: 4.674 Publication type: Letter or abstract Authors: Lopez-Corral, Lucia, Perez, Ariadna, Jimenez, Maria Jose, Sanchez-Ortega, Isabel, Alonso, Laura, Sisinni, Luisa, Fox, Laura, Villacampa, Guillermo, Badell, Isabel, de Heredia, Cristina Diaz et al. DOI: 10.1038/s41409-019-0471-y
PMID: 30001893 Journal: MEDICINA CLINICA Year: 2019 Reference: Med Clin (Barc). 2019 Feb 15;152(4):135-140. doi: 10.1016/j.medcli.2018.05.013. Epub 2018 Jul 9. Impact factor: 1.277 Publication type: Paper in national publication Authors: Alonso, Laura, Gonzalez-Vicent, Marta, Belendez, Cristina, Badell, Isabel, Sastre, Ana, Rodriguez-Villa, Antonia, Bermudez-Cortes, Mar, Hladun, Raquel, Diaz de Heredia, Cristina et al. DOI: 10.1016/j.medcli.2018.05.013
PMID: 30679331 Journal: HAEMATOLOGICA Year: 2019 Reference: Haematologica. 2019 Aug;104(8):e335-e339. doi: 10.3324/haematol.2018.206623. Epub 2019 Jan 24. Impact factor: 7.57 Publication type: Letter whit IF Authors: Sierra, Jorge, Uckan-Cetinkaya, Duygu, Skorobogatova, Elena, Antmen, Ali Bulent, Dalle, Jean-Hugues, Markiewicz, Miroslaw, Hamladji, Rose Marie, Kitra-Roussou, Vassiliki, La Nasa, Giorgio, Krivan, Gergely et al. DOI: 10.3324/haematol.2018.206623
PMID: 30660643 Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY Year: 2019 Reference: J Allergy Clin Immunol. 2019 Jun;143(6):2238-2253. doi: 10.1016/j.jaci.2018.12.1010. Epub 2019 Jan 17. Impact factor: 14.11 Publication type: Paper in international publication Authors: Lindemans, Caroline A, Soncini, Elena, Porta, Fulvio, Al-Mousa, Hamoud, Al-Saud, Bandar, Al-Dhekri, Hasan, Arnaout, Rand, Formankova, Renata, Bertrand, Yves, Lange, Andrzej et al. DOI: 10.1016/j.jaci.2018.12.1010
The association, once again, has shown its commitment to oncological research with a donation of €19,197 to the Cancer and Hematological Diseases Group for Children at VHIR.
The prestigious journal The Lancet has published the results of this study, which is the result of more than 20 years of pre-clinical research and 7 years of patient follow-up.
During the meeting, the role of the Vall d'Hebron Paediatric Research Hub in promoting research on children and adolescents was highlighted.
