About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.
With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.
In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.
IP: Francesc Moreso Mateos Collaborators: Gema Ariceta Iraola, Joan López Hellin Funding agency: Instituto de Salud Carlos III Funding: 42900 Reference: PMP22/00119 Duration: 01/01/2023 - 31/12/2025
IP: Concepció Jacobs Cachá Collaborators: Manuel Hernández González, Natalia Ramos Terrades, Joana Sellarés Roig, Carmen Llorens Cebriá, Janire Perurena Prieto Funding agency: Sociedad Española de Nefrología (S.E.N.) Funding: 24000 Reference: SENEFRO/PROJECTES/2023/JACOBS Duration: 23/12/2023 - 22/12/2025
IP: Ibane Abasolo Olaortua Collaborators: Joaquin Seras Franzoso, Fernanda Raquel Da Silva Andrade, Fernanda Raquel Da Silva Andrade, Fernanda Raquel Da Silva Andrade, Fernanda Raquel Da Silva Andrade Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 333099 Reference: CPP2022-009780 Duration: 01/07/2023 - 30/06/2026
IP: - Collaborators: Miriam Izquierdo Sans, Diana Fernandes de Rafael, Simon Schwartz Navarro Funding agency: EUROPEAN COMMISSION Funding: 221390.88 Reference: HYDROTEC_HE-MSCA-PF-GF2022 Duration: 01/01/2024 - 31/12/2026
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PMID: 38074506 Journal: JHEP Reports Year: 2024 Reference: JHEP Rep. 2023 Oct 12;6(1):100932. doi: 10.1016/j.jhepr.2023.100932. eCollection 2024 Jan. Impact factor: Publication type: Paper in international publication Authors: Banares, Juan; Barreira-Diaz, Ana; Blanco-Grau, Albert; Buti, Maria; Campins, Magda; Casado, Miguel Angel; Colom, Joan; Dominguez-Hernandez, Raquel; Esteban, Rafael; Falco-Roget, Anna et al. DOI: 10.1016/j.jhepr.2023.100932
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PMID: 36834836 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2023 Reference: Int J Mol Sci. 2023 Feb 8;24(4):3427. doi: 10.3390/ijms24043427. Impact factor: Publication type: Review in international publication Authors: Alvarez, Francisco J; Alvarez, Francisco J; Bedard, Patricia W; Jacobs-Cacha, Conxita; Llorens-Cebria, Carmen; Martinez-Diaz, Irene; Martos, Nerea; Soler, Maria Jose; Vergara, Ander et al. DOI: 10.3390/ijms24043427
PMID: 36839798 Journal: Pharmaceutics Year: 2023 Reference: Pharmaceutics. 2023 Jan 31;15(2):474. doi: 10.3390/pharmaceutics15020474. Impact factor: Publication type: Paper in international publication Authors: Abaca, Paulina; Andrade, Fernanda; Bustos, Daniel; Cabrera-Barjas, Gustavo; Duran-Lara, Esteban F; Marican, Adolfo; Pereira, Alfredo; Rafael, Diana; Valdes, Oscar; Valdes-Munoz, Elizabeth et al. DOI: 10.3390/pharmaceutics15020474
PMID: 36851800 Journal: Viruses-Basel Year: 2023 Reference: Viruses. 2023 Feb 20;15(2):587. doi: 10.3390/v15020587. Impact factor: Publication type: Review in international publication Authors: Andres, Cristina; Anton, Andres; Campos, Carolina; Colomer-Castell, Sergi; Garcia-Cehic, Damir; Gonzalez-Sanchez, Alejandra; Gregori, Josep; Ibanez-Lligona, Marta; Pinana, Maria; Pumarola, Tomas et al. DOI: 10.3390/v15020587
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PMID: 34471422 Journal: Therapeutic Advances in Gastroenterology Year: 2021 Reference: Therap Adv Gastroenterol. 2021 Aug 27;14:17562848211016563. doi: 10.1177/17562848211016563. eCollection 2021. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Colom, Joan; Daigre, Constanza; Esteban, Rafael; Grau-Lopez, Lara; Llaneras, Jordi; Marcos-Fosch, Cristina; Martinez-Luna, Nieves; Palma-Alvarez, Raul Felipe; Palma-Alvarez, Raul Felipe et al. DOI: 10.1177/17562848211016563
PMID: 34433852 Journal: Scientific Reports Year: 2021 Reference: Sci Rep. 2021 Aug 25;11(1):17063. doi: 10.1038/s41598-021-96350-3. Impact factor: Publication type: Paper in international publication Authors: Araujo, Silvia G; Buti, Maria; Fernandez, Emma; Lazarus, Jeffrey V; Lens, Sabela; Nomah, Daniel K; Picchio, Camila A; Rando-Segura, Ariadna; Rodriguez-Frias, Francisco; Rodriguez-Tajes, Sergio et al. DOI: 10.1038/s41598-021-96350-3
PMID: 34402744 Journal: Emerging Microbes & Infections Year: 2021 Reference: Emerg Microbes Infect. 2021 Dec;10(1):1777-1789. doi: 10.1080/22221751.2021.1969868. Impact factor: Publication type: Paper in international publication Authors: Abril, Josep Francesc; Andres, Cristina; Anton, Andres; Campos, Carolina; Castillo, Carla; Codina, Maria Gema; Colomer-Castell, Sergi; Cortese, Maria Francesca; Esperalba, Juliana; Esteban, Juan Ignacio et al. DOI: 10.1080/22221751.2021.1969868
PMID: 34374649 Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY Year: 2021 Reference: Eur J Endocrinol. 2021 Sep 1;185(4):587-595. doi: 10.1530/EJE-21-0561. Impact factor: Publication type: Paper in international publication Authors: Biagetti, Betina; Casteras, Anna; Cordero Asanza, Esteban; Giralt-Arnaiz, Marina; Hernandez, Irene; Martinez-Saez, Elena; Ng-Wong, Yiken Karelys; Sarria-Estrada, Silvana; Simo, Rafael et al. DOI: 10.1530/EJE-21-0561
PMID: 32531085 Journal: BRITISH JOURNAL OF HAEMATOLOGY Year: 2020 Reference: Br J Haematol. 2020 Aug;190(4):520-524. doi: 10.1111/bjh.16938. Epub 2020 Jul 28. Impact factor: Publication type: Paper in international publication Authors: Casis, Ernesto; Paciucci, Rosanna; Thomson, Timothy M; Toscano, Emily et al. DOI: 10.1111/bjh.16938
PMID: 32515985 Journal: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY Year: 2020 Reference: Am J Respir Cell Mol Biol. 2020 Oct;63(4):444-451. doi: 10.1165/rcmb.2020-0021OC. Impact factor: Publication type: Paper in international publication Authors: Baladron, Beatriz; Belmonte, Irene; Blanco, Ignacio; Gomez-Mariano, Gema; Hernandez-Perez, Jose Maria; Janciauskiene, Sabina; Martinez-Delgado, Beatriz; Matamala, Nerea; Michel, Francisco Javier; Perez, Jose Antonio et al. DOI: 10.1165/rcmb.2020-0021OC
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PMID: 32409071 Journal: Materials Science & Engineering C-Materials for Biological Applications Year: 2020 Reference: Mater Sci Eng C Mater Biol Appl. 2020 Jul;112:110920. doi: 10.1016/j.msec.2020.110920. Epub 2020 Apr 3. Impact factor: Publication type: Paper in international publication Authors: Almeida, Andreia; Andrade, Fernanda; Araujo, Marco; Goncalves, Hugo; Lucio, Marlene; Novoa-Carballal, Ramon; Reis, Rui L; Sarmento, Bruno; Schwartz, Simo Jr et al. DOI: 10.1016/j.msec.2020.110920
PMID: 30843440 Journal: CHRONOBIOLOGY INTERNATIONAL Year: 2019 Reference: Chronobiol Int. 2019 May;36(5):672-680. doi: 10.1080/07420528.2019.1580716. Epub 2019 Mar 7. Impact factor: Publication type: Paper in international publication Authors: Baena-Fustegueras, Juan A; Balibrea, Jose Maria; Cambras, Trinitat; Carmona, Julia; Caubet, Enric; Cuello, Elena; Diez-Noguera, Antoni; Ferrer, Roser; Fort, Jose Manuel; Gonzalez, Oscar et al. DOI: 10.1080/07420528.2019.1580716
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PMID: 30768983 Journal: GASTROENTEROLOGY Year: 2019 Reference: Gastroenterology. 2019 May;156(6):1820-1833. doi: 10.1053/j.gastro.2019.02.003. Epub 2019 Feb 12. Impact factor: Publication type: Paper in international publication Authors: Alavian, Seyed Moayed; Alizei, Elahe Salimi; Bockmann, Jan; Budeus, Bettina; Buti, Maria; Casillas, Rosario; Cornberg, Markus; Emmerich, Florian; Gostick, Emma; Heinold, Andreas et al. DOI: 10.1053/j.gastro.2019.02.003
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PMID: 22257075 Journal: HIV MEDICINE Year: 2012 Reference: HIV Med. 2012 Jul;13(6):379-83. doi: 10.1111/j.1468-1293.2011.00985.x. Epub 2012 Jan 18. Impact factor: Publication type: Paper in international publication Authors: ; ; ; ; ; ; ; ; ; et al. DOI: 10.1111/j.1468-1293.2011.00985.x
PMID: 19275492 Journal: CLINICAL INFECTIOUS DISEASES Year: 2009 Reference: Clin Infect Dis. 2009 Apr 15;48(8):1152-9. Impact factor: Publication type: Paper in international publication Authors: Carbonell, Judit; Crespo, Manuel; Curran, Adria; Esteban, Juan I; Esteban, Rafael; Falco, Vicenc; Imaz, Arkaitz; Jardi, Rosend; Ocana, Inma; Pahissa, Albert et al. DOI: 10.1086/597470
PMID: 19781833 Journal: AMERICAN JOURNAL OF KIDNEY DISEASES Year: 2009 Reference: Am J Kidney Dis. 2009 Nov;54(5):871-80. Impact factor: Publication type: Paper in international publication Authors: ; ; ; ; ; ; ; ; ; et al. DOI: 10.1053/j.ajkd.2009.07.011
Based on the study led by VHIR, a clinical trial has been approved for patients with locally advanced pancreatic cancer.
Vall d'Hebron participates in a project to develop innovative microsampling technology, making blood collection more accessible and patient-centered.
Researchers from all over Europe gathered to kick off the SPM4.0 project, an innovative Marie Curie Skłodowska (MSCA-DN) doctoral network that promotes the development of autonomous Scanning Probe Microscopy with AI.
