About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.
With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.
In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.
IP: - Collaborators: Fernanda Raquel Da Silva Andrade, Miriam Izquierdo Sans Funding agency: Asociación Española Contra el Cáncer Funding: 100000 Reference: INVES211530DASI Duration: 01/09/2021 - 31/08/2025
IP: - Collaborators: Diego Baranda Martínez-Abasca, Miriam Izquierdo Sans Funding agency: Ministerio de Educación, Cultura y Deporte Funding: 59223.42 Reference: FPU20/04210 Duration: 01/12/2021 - 31/03/2025
IP: Marta Martínez Vicente Collaborators: José Antonio Arranz Amo, Jorge Hernández Vara, Eddie Pradas Gracia, Guillem Pintos Morell, Clara Carnicer Cáceres, Carles Lorenzo Bosquet, David Moreno Martinez, Jordi Riera Heredia, The Vall d’Hebron Iniciative for Parkinson associated to GBA (VHIP-GBA): from biospecimen collection to translational studies an, Daniela Samaniego Toro, Laura Castillo Ribelles, Daniela Samaniego Toro Funding agency: Instituto de Salud Carlos III Funding: 245932.5 Reference: PI20/00728 Duration: 01/01/2021 - 30/06/2025
IP: Olga Simó Servat Collaborators: Ana Boixadera Espax, Marina Giralt Arnaiz, Cristina Udina Argilaga Funding agency: Instituto de Salud Carlos III Funding: 82280 Reference: PI20/01703 Duration: 01/01/2021 - 30/06/2025
PMID: 37443087 Journal: Orphanet Journal of Rare Diseases Year: 2023 Reference: Orphanet J Rare Dis. 2023 Jul 13;18(1):188. doi: 10.1186/s13023-023-02793-4. Impact factor: Publication type: Letter or abstract Authors: Argudo, Ana; Arranz, Jose Antonio; Artuch, Rafael; Carnicer, Clara; de Aledo-Castillo, Jose Manuel Gonzalez; de Los Santos, Mariela Mercedes; Fernandez, Rosa; Garcia-Cazorla, Angeles; Garcia-Villoria, Judit; Garcia-Volpe, Camila et al. DOI: 10.1186/s13023-023-02793-4
PMID: 37555464 Journal: BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Year: 2023 Reference: BJOG. 2023 Aug 9. doi: 10.1111/1471-0528.17631. Impact factor: Publication type: Paper in international publication Authors: Alsius, Merce; Bonacina, Erika; Caamina, Sara; Carreras, Elena; Castillo-Ribelles, Laura; de Mingo, Laura; Diaz, Sonia; Garcia, Esperanza; Garcia-Manau, Pablo; Lopez, Monica et al. DOI: 10.1111/1471-0528.17631
PMID: 37570527 Journal: Nanomaterials Year: 2023 Reference: Nanomaterials (Basel). 2023 Jul 29;13(15):2208. doi: 10.3390/nano13152208. Impact factor: Publication type: Paper in international publication Authors: Abasolo, Ibane; Bastus, Neus G; Bastus, Neus G; Boullosa, Ana Maria; Boullosa, Ana Maria; Camara, Juan Antonio; Casals, Eudald; Garcia, Ana; Gusta, Muriel F; Mondragon, Laura et al. DOI: 10.3390/nano13152208
PMID: 37569568 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2023 Reference: Int J Mol Sci. 2023 Jul 29;24(15):12183. doi: 10.3390/ijms241512183. Impact factor: Publication type: Paper in international publication Authors: Bes, Marta; Borras, Francesc E; Burgui, Idoia; Camos, Silvia; Corrales, Irene; Costafreda, Maria Isabel; Domingo, Esteban; Esteban, Juan Ignacio; Llorens-Revull, Meritxell; Martinez-Gonzalez, Brenda et al. DOI: 10.3390/ijms241512183
PMID: 35453428 Journal: Antioxidants Year: 2022 Reference: Antioxidants (Basel). 2022 Apr 8;11(4). pii: antiox11040741. doi: 10.3390/antiox11040741. Impact factor: Publication type: Paper in international publication Authors: Blazquez, Alberto; Bujan, Nuria; Carnicer, Clara; Cortes, Ana Belen; Delmiro, Aitor; Fernandez-Moreno, Miguel Angel; Garcia-Arumi, Elena; Garcia-Garcia, Francesc J; Garrabou, Gloria; Gonzalez, Cristina et al. DOI: 10.3390/antiox11040741
PMID: 34706167 Journal: Advanced Healthcare Materials Year: 2022 Reference: Adv Healthc Mater. 2022 Apr;11(7):e2101544. doi: 10.1002/adhm.202101544. Epub 2021 Nov 10. Impact factor: Publication type: Paper in international publication Authors: Abasolo, Ibane; Arminan, Ana; Bogdanska, Anna; Borgos, Sven Even; Calzolai, Luigi; Fernandez, Yolanda; Foradada, Laia; Gallon, Elena; Garcia-Aranda, Natalia; Gimenez, Vanessa et al. DOI: 10.1002/adhm.202101544
PMID: 35377229 Journal: Microbiology Spectrum Year: 2022 Reference: Microbiol Spectr. 2022 Apr 27;10(2):e0214921. doi: 10.1128/spectrum.02149-21. Epub 2022 Apr 4. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Casillas, Rosario; Cortese, Maria Francesca; Esteban, Rafael; Ferrer-Costa, Roser; Garcia-Garcia, Selene; Kuchta, Alison; Pacin, Beatriz; Palom, Adriana; Pumarola, Tomas et al. DOI: 10.1128/spectrum.02149-21
PMID: 35351135 Journal: BMC Medicine Year: 2022 Reference: BMC Med. 2022 Mar 29;20(1):129. doi: 10.1186/s12916-022-02345-w. Impact factor: Publication type: Paper in international publication Authors: Arrese-Munoz, Iria; Borrell, Ricardo Pujol; Diaz-Troyano, Noelia; Ferrer, Roser; Gabriel-Medina, Pablo; Gallo, Monica Martinez; Gine, Anna; Hernandez-Gonzalez, Manuel; Labrador-Horrillo, Moises; Martinez-Valle, Fernando et al. DOI: 10.1186/s12916-022-02345-w
PMID: 33982741 Journal: Nanoscale Year: 2021 Reference: Nanoscale. 2021 May 27;13(20):9280-9292. doi: 10.1039/d1nr00146a. Impact factor: Publication type: Paper in international publication Authors: Abasolo, Ibane; Bertrand, Jean-Remi; Cigler, Petr; Claveau, Sandra; Delen, Xavier; Diaz-Riascos, Zamira V; Georges, Patrick; Kindermann, Marek; Lopez-Alemany, Roser; Papine, Alexandre et al. DOI: 10.1039/d1nr00146a
PMID: 33965935 Journal: Obesity Facts Year: 2021 Reference: Obes Facts. 2021;14(3):291-297. doi: 10.1159/000515598. Epub 2021 May 7. Impact factor: Publication type: Paper in international publication Authors: Ciudin, Andreea; Comas, Marta; Cordero, Efrain; Ferrer, Roser; Fidilio, Enzamaria; Giralt, Marina; Gonzalez, Carla; Hernandez, Cristina; Hernandez, Irene; Lopez, Natividad et al. DOI: 10.1159/000515598
PMID: 33947532 Journal: Materials Science & Engineering C-Materials for Biological Applications Year: 2021 Reference: Mater Sci Eng C Mater Biol Appl. 2021 May;124:112024. doi: 10.1016/j.msec.2021.112024. Epub 2021 Mar 10. Impact factor: Publication type: Paper in international publication Authors: Abasolo, Ibane; Aguilar, Maria Rosa; Camara-Sanchez, Patricia; Espinosa-Cano, Eva; Huerta-Madronal, Miguel; San Roman, Julio; Schwartz, Simo Jr; Seras-Franzoso, Joaquin et al. DOI: 10.1016/j.msec.2021.112024
PMID: 33931066 Journal: Orphanet Journal of Rare Diseases Year: 2021 Reference: Orphanet J Rare Dis. 2021 Apr 30;16(1):195. doi: 10.1186/s13023-021-01784-7. Impact factor: Publication type: Paper in international publication Authors: Argudo, Ana; Arranz, Jose Antonio; Artuch, Rafael; Carnicer, Clara; de Aledo-Castillo, Jose Manuel Gonzalez; de Los Santos, Mariela Mercedes; Del Toro, Mireia; Fernandez, Rosa; Garcia-Cazorla, Angeles; Garcia-Villoria, Judit et al. DOI: 10.1186/s13023-021-01784-7
PMID: 31869590 Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES Year: 2020 Reference: J Neurol Sci. 2020 Feb 15;409:116635. doi: 10.1016/j.jns.2019.116635. Epub 2019 Dec 14. Impact factor: Publication type: Paper in international publication Authors: Delgado, Pilar; Espinel, Eugenia; Jimenez-Balado, Joan; Maisterra, Olga; Palasi, Antoni; Penalba, Anna; Pizarro, Jesus; Pujadas, Francesc; Ramirez, Clara; Ramos, Natalia et al. DOI: 10.1016/j.jns.2019.116635
PMID: 32003834 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2020 Reference: Nephrol Dial Transplant. 2020 Jan 1;35(Supplement_1):i13-i23. doi: 10.1093/ndt/gfz237. Impact factor: Publication type: Paper in international publication Authors: Gorriz, Jose Luis; Jacobs-Cacha, Conxita; Martinez-Castelao, Alberto; Navarro-Gonzalez, Juan F; Nunez, Julio; Ortiz, Alberto; Soler, Maria Jose; Vergara, Ander et al. DOI: 10.1093/ndt/gfz237
PMID: 31805583 Journal: SEMINARS IN LIVER DISEASE Year: 2020 Reference: Semin Liver Dis. 2020 Feb;40(1):49-60. doi: 10.1055/s-0039-3401031. Epub 2019 Dec 5. Impact factor: Publication type: Review in international publication Authors: Buti, Maria; Esteban, Rafael; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco; Tabernero, David et al. DOI: 10.1055/s-0039-3401031
PMID: 31865857 Journal: LUPUS Year: 2020 Reference: Lupus. 2020 Feb;29(2):118-125. doi: 10.1177/0961203319896018. Epub 2019 Dec 22. Impact factor: Publication type: Paper in international publication Authors: Agraz, I; Arredondo, K V; Carnicer, C; Jaramillo, J; Jatem, E; Ostos, E; Ramos, N; Salcedo, M T; Segarra, A; Valtierra, N et al. DOI: 10.1177/0961203319896018
PMID: 29174468 Journal: NEUROMUSCULAR DISORDERS Year: 2018 Reference: Neuromuscul Disord. 2018 Feb;28(2):137-143. doi: 10.1016/j.nmd.2017.10.006. Epub 2017 Oct 31. Impact factor: Publication type: Paper in international publication Authors: Ariatti, Alessandra; Carnicer-Caceres, Clara; Carreno-Gago, Lidia; de Luna, Noemi; Devigili, Grazia; Garcia-Arumi, Elena; Pinos, Tomas; Russignan, Anna; Scarpelli, Mauro; Tonin, Paola et al. DOI: 10.1016/j.nmd.2017.10.006
PMID: 29456407 Journal: WORLD JOURNAL OF GASTROENTEROLOGY Year: 2018 Reference: World J Gastroenterol. 2018 Feb 14;24(6):680-692. doi: 10.3748/wjg.v24.i6.680. Impact factor: Publication type: Paper in international publication Authors: Belmonte, Irene; Buti, Maria; Casillas, Rosario; Cortese, Maria Francesca; Esteban, Rafael; Gonzalez, Carolina; Gregori, Josep; Lopez, Rosa Maria; Quer, Josep; Riveiro-Barciela, Mar et al. DOI: 10.3748/wjg.v24.i6.680
PMID: 29146701 Journal: Clinical Journal of the American Society of Nephrology Year: 2018 Reference: Clin J Am Soc Nephrol. 2018 Feb 7;13(2):258-264. doi: 10.2215/CJN.02530317. Epub 2017 Nov 16. Impact factor: Publication type: Paper in international publication Authors: Agraz, Irene; Ariceta, Gema; Arredondo, Karla V; Carnicer, Clara; Jaramillo, Juliana; Jatem, Elias; Lara, Luis Enrique; Madrid, Alvaro; Martinez, Cristina; Ostos, Elena et al. DOI: 10.2215/CJN.02530317
PMID: 29336994 Journal: MOLECULAR GENETICS AND METABOLISM Year: 2018 Reference: Mol Genet Metab. 2018 Feb;123(2):69-75. doi: 10.1016/j.ymgme.2018.01.002. Epub 2018 Jan 5. Impact factor: Publication type: Review in national publication Authors: Miguel-Huguet, Bernat; Molto-Abad, Marc; Munoz-Delgado, Cecilia; Pardo-Mateos, Almudena; Perez-Lopez, Jordi; Sampayo-Cordero, Miguel et al. DOI: 10.1016/j.ymgme.2018.01.002
PMID: 24637729 Journal: J CLIN GASTROENTEROL Year: 2015 Reference: J Clin Gastroenterol. 2015 Feb;49(2):165-8. doi: 10.1097/MCG.0000000000000113. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Girones, Rosa; Minguez, Beatriz; Quer, Josep; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco et al. DOI: 10.1097/MCG.0000000000000113
PMID: 24390735 Journal: CANCER RESEARCH Year: 2014 Reference: Cancer Res. 2014 Mar 1;74(5):1416-28. doi: 10.1158/0008-5472.CAN-13-1671. Epub 2014 Jan 3. Impact factor: Publication type: Paper in international publication Authors: Cuadros, Thais; de Torres, Ines; Itarte, Emilio; Lopez-Hellin, Joan; Meseguer, Anna; Morote, Juan; Ramon Y Cajal, Santiago; Salcedo, Mayte; Sanchez, Alex; Sarro, Eduard et al. DOI: 10.1158/0008-5472.CAN-13-1671
Based on the study led by VHIR, a clinical trial has been approved for patients with locally advanced pancreatic cancer.
Vall d'Hebron participates in a project to develop innovative microsampling technology, making blood collection more accessible and patient-centered.
Researchers from all over Europe gathered to kick off the SPM4.0 project, an innovative Marie Curie Skłodowska (MSCA-DN) doctoral network that promotes the development of autonomous Scanning Probe Microscopy with AI.
