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Clinical Biochemistry, Drug Delivery & Therapy

The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.

With a direct link to the Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.

In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.

Team

José Antonio Arranz Amo

José Antonio Arranz Amo

Postdoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Laura Castellote Bellés

Laura Castellote Bellés

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Laura Castillo Ribelles

Laura Castillo Ribelles

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Maria del Carmen Sanchez Valcarcel

Maria del Carmen Sanchez Valcarcel

Research assistant
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mireia Benito Jimenez

Mireia Benito Jimenez

Research assistant
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mª Teresa Gené Juyent

Mª Teresa Gené Juyent

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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José Antonio Arranz Amo

José Antonio Arranz Amo

Postdoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Laura Castellote Bellés

Laura Castellote Bellés

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Laura Castillo Ribelles

Laura Castillo Ribelles

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Maria del Carmen Sanchez Valcarcel

Maria del Carmen Sanchez Valcarcel

Research assistant
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mireia Benito Jimenez

Mireia Benito Jimenez

Research assistant
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mª Teresa Gené Juyent

Mª Teresa Gené Juyent

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more

Projects

Impacto y valor pronóstico de vesículas extracelulares tumorales provenientes de células madre cancerígenas en tumores de mama triple negativo.

IP: Joaquin Seras Franzoso
Collaborators: Laura García Latorre, Impacto y valor pronóstico de vesículas extracelulares tumorales provenientes de células madre cancerígenas en tumores de mama t, Esther Zamora Adelantado, Sandra Mancilla Zamora, Zamira Vanessa Diaz Riascos, Belen Garcia Prats
Funding agency: Instituto de Salud Carlos III
Funding: 99220
Reference: PI22/01301
Duration: 01/01/2023 - 31/12/2026

Desentrañando las vías protectoras de los SGLT2i y GLP-1RA en la enfermedad renal diabética: papel de las proteínas adaptadoras MAP17 y D-AKAP-2 en ratones db/db y organoides renales humanos.

IP: Maria Jose Soler Romeo
Collaborators: Alejandra Gabaldon Dominguez, Mario Alonso Narvaez Barros, Pamela Dominguez Baez, Irene Martinez Diaz, Sheila Bermejo Garcia, Alejandra Planas Vilaseca, Concepció Jacobs Cachá, Desentrañando las vías protectoras de los SGLT2i y GLP-1RA en la enfermedad renal diabética: papel de las proteínas adaptadoras
Funding agency: Instituto de Salud Carlos III
Funding: 122210
Reference: PI21/01292
Duration: 01/01/2022 - 30/06/2026

Blog

News

The project’s 4th annual meeting was recently held as part of the Fortalece–Salud programme of the Carlos III Health Institute.

The families of the professionals had the opportunity to visit the facilities and discover how we work at the institution.

The new system, made of cellulose and chitosan, enables sustained release of docetaxel and has demonstrated antitumor activity in preclinical models of ovarian cancer and glioblastoma.