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Clinical Biochemistry, Drug Delivery & Therapy

The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.

With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.

In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.

Team

Mª Pilar Felipe Fernandez

Mª Pilar Felipe Fernandez

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mª Teresa Gené Juyent

Mª Teresa Gené Juyent

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Noelia Díaz Troyano

Noelia Díaz Troyano

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Pablo Gabriel Medina

Pablo Gabriel Medina

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Pilar Bonet Palomares

Pilar Bonet Palomares

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Raquel  Barquin Del Pino

Raquel Barquin Del Pino

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mª Pilar Felipe Fernandez

Mª Pilar Felipe Fernandez

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mª Teresa Gené Juyent

Mª Teresa Gené Juyent

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Noelia Díaz Troyano

Noelia Díaz Troyano

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Pablo Gabriel Medina

Pablo Gabriel Medina

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Pilar Bonet Palomares

Pilar Bonet Palomares

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Raquel  Barquin Del Pino

Raquel Barquin Del Pino

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Projects

Demencia mixta por Alzheimer y enfermedad cerebrovascular: un estudio clínico y experimental.

IP: Maria Pilar Delgado Martínez
Collaborators: Francesc Pujadas Navinés, Olga Maisterra Santos, Laura Castillo Ribelles, Carles Lorenzo Bosquet, Antonio Palasi Franco, Maria Belén Gutiérrez Iglesias, Jesús Pizarro Gonzálvez, Diana Liebana Gutierrez
Funding agency: Instituto de Salud Carlos III
Funding: 134310
Reference: PI19/00217
Duration: 01/01/2020 - 30/06/2024

The Vall d’Hebron Iniciative for Parkinson associated to GBA (VHIP-GBA): from biospecimen collection to translational studies and therapies.

IP: Marta Martínez Vicente
Collaborators: José Antonio Arranz Amo, Jorge Hernández Vara, Eddie Pradas Gracia, Guillem Pintos Morell, Clara Carnicer Cáceres, Carles Lorenzo Bosquet, David Moreno Martinez, Jordi Riera Heredia, Marta Montpeyó Garcia-Moreno, Daniela Samaniego Toro, Laura Castillo Ribelles, Daniela Samaniego Toro
Funding agency: Instituto de Salud Carlos III
Funding: 245932.5
Reference: PI20/00728
Duration: 01/01/2021 - 30/06/2025

Role of sarcopenia in the evolution of morbidly obese patients who undergo bariatric surgery. Study of cohorts and mechanisms involved.

IP: Andreea Ciudin Mihai
Collaborators: Oscar González López, Fiorella Ximena Palmas Candia, Marina Giralt Arnaiz, Marta Comas Martínez, Rosa Burgos Peláez, Irene Hernández Hernández, Enzamaría Fidilio Meli, Efráin Santiago Cordero Vázquez, Cristina Gamez Cenzano
Funding agency: Instituto de Salud Carlos III
Funding: 123420
Reference: PI20/01086
Duration: 01/01/2021 - 31/12/2024

Microperimetry and serum biomarkers for identifying type 2 diabetic patients with cognitive impairment. A cross-sectional and prospective study.

IP: Olga Simó Servat
Collaborators: Ana Boixadera Espax, Marina Giralt Arnaiz, Cristina Udina Argilaga
Funding agency: Instituto de Salud Carlos III
Funding: 82280
Reference: PI20/01703
Duration: 01/01/2021 - 30/06/2025

Publications

A new era for Advances in Laboratory Medicine.

PMID: 38075176
Journal: Advances in Laboratory Medicine
Year: 2023
Reference: Adv Lab Med. 2023 Sep 13;4(3):203-204. doi: 10.1515/almed-2023-0116. eCollection 2023 Sep.
Impact factor:
Publication type: Editorail in international publication
Authors: Arribas, Ignacio; Fernandez-Calle, Pilar; Ferrer-Costa, Roser; Gonzalez, Alvaro; Jimenez, Wladimiro et al.
DOI: 10.1515/almed-2023-0116

[Not Available].

PMID: 38075162
Journal: Advances in Laboratory Medicine
Year: 2023
Reference: Adv Lab Med. 2023 Sep 8;4(3):205-206. doi: 10.1515/almed-2023-0113. eCollection 2023 Sep.
Impact factor:
Publication type: Editorial in national publication
Authors: Arribas, Ignacio; Fernandez-Calle, Pilar; Ferrer-Costa, Roser; Gonzalez, Alvaro; Jimenez, Wladimiro et al.
DOI: 10.1515/almed-2023-0113

Community-based screening enhances hepatitis B virus linkage to care among West African migrants in Spain.

PMID: 38097770
Journal: Communications medicine
Year: 2023
Reference: Commun Med (Lond). 2023 Dec 14;3(1):182. doi: 10.1038/s43856-023-00420-8.
Impact factor:
Publication type: Paper in international publication
Authors: Araujo, Silvia G; Buti, Maria; Fernandez, Emma; Forns, Xavier; Lazarus, Jeffrey V; Lens, Sabela; MacKinnon, Marina; Martro, Elisa; Nomah, Daniel K; Nunez, Carmen Lopez et al.
DOI: 10.1038/s43856-023-00420-8

Assessing the rate of non-linkage to care and identifying barriers in individuals living with hepatitis B. Results of the LINK-B study.

PMID: 38111084
Journal: LIVER INTERNATIONAL
Year: 2023
Reference: Liver Int. 2023 Dec 18. doi: 10.1111/liv.15814.
Impact factor:
Publication type: Paper in international publication
Authors: Barreira-Diaz, Ana; Buti, Maria; Esteban, Rafael; Feliu-Prius, Anna; Palom, Adriana; Rando, Ariadna; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco; Ruiz-Cobo, Juan C; Vargas-Accarino, Elena et al.
DOI: 10.1111/liv.15814

Blog

News

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

The European Rare Diseases Research Alliance (ERDERA) kicked off this September, with an estimated budget of 380 million euros and the aim of improving the lives of 30 million rare disease patients in Europe and beyond.

Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.