About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.
With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.
In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.
IP: Ibane Abasolo Olaortua Collaborators: Joaquin Seras Franzoso, Guillem Pintos Morell, Zamira Vanessa Diaz Riascos, Simon Schwartz Navarro, Julia German Cortes, Angels Alcina Mila Funding agency: EUROPEAN COMMISSION Funding: 457250 Reference: MIMIC-KEY_H2020-FETPROACT-2020 Duration: 01/06/2021 - 31/05/2025
IP: Ibane Abasolo Olaortua Collaborators: - Funding agency: Agence Nationale de la Recherche Funding: 0.01 Reference: EVERETT_ANR-BIOPNSE2020 Duration: 01/11/2022 - 31/10/2025
IP: Ibane Abasolo Olaortua Collaborators: Laura García Latorre, Guillem Pintos Morell, Sandra Mancilla Zamora, Zamira Vanessa Diaz Riascos, Marc Miquel Moltó Abad, Zamira Vanessa Diaz Riascos, Zamira Vanessa Diaz Riascos, Zamira Vanessa Diaz Riascos, Zamira Vanessa Diaz Riascos, Zamira Vanessa Diaz Riascos, Zamira Vanessa Diaz Riascos, Zamira Vanessa Diaz Riascos, Zamira Vanessa Diaz Riascos, Zamira Vanessa Diaz Riascos Funding agency: Instituto de Salud Carlos III Funding: 153670 Reference: PI21/00936 Duration: 01/01/2022 - 30/06/2025
IP: Maria Jose Soler Romeo Collaborators: Mario Alonso Narvaez Barros, Pamela Dominguez Baez, Sheila Bermejo Garcia, Alejandra Planas Vilaseca, Concepció Jacobs Cachá, Juan Carlos León Román, Irene Martinez Diaz Funding agency: Instituto de Salud Carlos III Funding: 122210 Reference: PI21/01292 Duration: 01/01/2022 - 30/06/2026
PMID: 37593971 Journal: TRANSFUSION Year: 2023 Reference: Transfusion. 2023 Aug 18. doi: 10.1111/trf.17498. Impact factor: Publication type: Letter or abstract Authors: Alvarez Arguelles, Marta Elena; Garcia-Gala, Jose Maria; Mata, Pablo; Munoz, Maria Del Carmen; Ojea, Ana Maria; Quer Sivila, Josep; Quer Sivila, Josep; Rando Segura, Ariadna; Rodriguez, Mercedes; Rodriguez-Frias, Francisco et al. DOI: 10.1111/trf.17498
PMID: 37626646 Journal: Biomedicines Year: 2023 Reference: Biomedicines. 2023 Jul 30;11(8):2149. doi: 10.3390/biomedicines11082149. Impact factor: Publication type: Paper in international publication Authors: Baldira, Jaume; Chiscano, Luis; Comas, Inma; Cortes, Alejandro; Ferrer, Ricard; Ferrer-Costa, Roser; Gonzalez-Lopez, Juan Jose; Larrosa, Maria Nieves; Ruiz-Rodriguez, Juan Carlos; Ruiz-Sanmartin, Adolfo et al. DOI: 10.3390/biomedicines11082149
PMID: 37676213 Journal: JACC-Heart Failure Year: 2023 Reference: JACC Heart Fail. 2023 Aug 22:S2213-1779(23)00397-9. doi: 10.1016/j.jchf.2023.07.010. Impact factor: Publication type: Paper in international publication Authors: Amiguet, Martina; Amiguet, Martina; Bayes-Genis, Antoni; Bayes-Genis, Antonio; Bodi, Vicent; Civera, Jose; Climent, Herminio Morillas; Conesa, Adriana; Diaz Exposito, Arancha; Dominguez, Eloy et al. DOI: 10.1016/j.jchf.2023.07.010
PMID: 37696147 Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology Year: 2023 Reference: Eur J Obstet Gynecol Reprod Biol. 2023 Aug 23;289:203-207. doi: 10.1016/j.ejogrb.2023.08.376. Impact factor: Publication type: Paper in international publication Authors: Beneitez, D; Beneitez, D; Bergamo, S; Bergamo, S; Carbonell, M; Carbonell, M; Carreras, E; Carreras, E; Castillo, F; Castillo, F et al. DOI: 10.1016/j.ejogrb.2023.08.376
PMID: 35337007 Journal: Viruses-Basel Year: 2022 Reference: Viruses. 2022 Mar 14;14(3). pii: v14030600. doi: 10.3390/v14030600. Impact factor: Publication type: Review in international publication Authors: Andres, Cristina; Anton, Andres; Campos, Carolina; Colomer-Castell, Sergi; Cortese, Maria Francesca; Garcia-Cehic, Damir; Gonzalez-Sanchez, Alejandra; Ibanez, Marta; Pinana, Maria; Pumarola, Tomas et al. DOI: 10.3390/v14030600
PMID: 35229657 Journal: ANTIOXIDANTS & REDOX SIGNALING Year: 2022 Reference: Antioxid Redox Signal. 2022 Apr;36(10-12):729-739. doi: 10.1089/ars.2022.0018. Impact factor: Publication type: Paper in international publication Authors: Alegre-Martin, Jose; Castro-Marrero, Jesus; Cordobilla, Begona; Domingo, Joan Carles; Ferrer, Roser; Giralt, Marina; Sanmartin-Sentanes, Ramon et al. DOI: 10.1089/ars.2022.0018
PMID: 35232561 Journal: Endocrinologia Diabetes y Nutricion Year: 2022 Reference: Endocrinol Diabetes Nutr (Engl Ed). 2022 Jan;69(1):63-69. doi: 10.1016/j.endien.2022.01.001. Epub 2022 Feb 16. Impact factor: Publication type: Paper in international publication Authors: Alfayate Guerra, Rocio; Alvarez Garcia, Elias; Berlanga Escalera, Eugenio; Biagetti, Betina; Casals, Gregori; Esteban Salan, Margarita; Ferrer Costa, Roser; Garcia Lacalle, Concepcion; Gorrin Ramos, Jorge; Granada Ibern, Maria-Luisa et al. DOI: 10.1016/j.endien.2022.01.001
PMID: 35215809 Journal: Viruses-Basel Year: 2022 Reference: Viruses. 2022 Jan 22;14(2). pii: v14020215. doi: 10.3390/v14020215. Impact factor: Publication type: Paper in international publication Authors: Aldama, Unai; Buti, Maria; Casillas, Rosario; Cortese, Maria Francesca; Galan, Anna; Garcia-Garcia, Selene; Gonzalez-Aseguinolaza, Gloria; Gregori, Josep; Najarro, Adrian; Pacin-Ruiz, Beatriz et al. DOI: 10.3390/v14020215
PMID: 33923569 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 Apr 16;10(8). pii: jcm10081724. doi: 10.3390/jcm10081724. Impact factor: Publication type: Paper in international publication Authors: Barrecheguren, Miriam; Belmonte, Irene; Calle, Myriam; Esquinas, Cristina; Genesca, Joan; Miravitlles, Marc; Nunez, Alexa; Pons, Monica; Rodriguez, Esther; Rodriguez-Frias, Francisco et al. DOI: 10.3390/jcm10081724
PMID: 33924567 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 Apr 13;10(8). pii: jcm10081664. doi: 10.3390/jcm10081664. Impact factor: Publication type: Review in international publication Authors: Agraz-Pamplona, Irene; Armengol-Bellapart, Mar; Arranz-Amo, Jose Antonio; Camprodon-Gomez, Maria; Carnicer-Caceres, Clara; Cea-Arestin, Cristina; Del-Toro-Riera, Mireia; Hernandez-Vara, Jorge; Lucas-Del-Pozo, Sara; Molto-Abad, Marc et al. DOI: 10.3390/jcm10081664
PMID: 33903089 Journal: Endocrinologia Diabetes y Nutricion Year: 2021 Reference: Endocrinol Diabetes Nutr (Engl Ed). 2021 Apr 23:S2530-0164(21)00082-3. doi: 10.1016/j.endinu.2020.12.002. Impact factor: Publication type: Paper in national publication Authors: Alfayate Guerra, Rocio; Alvarez Garcia, Elias; Berlanga Escalera, Eugenio; Biagetti, Betina; Casals, Gregori; Esteban Salan, Margarita; Ferrer Costa, Roser; Garcia Lacalle, Concepcion; Gorrin Ramos, Jorge; Granada Ibern, Maria-Luisa et al. DOI: 10.1016/j.endinu.2020.12.002
PMID: 33892786 Journal: Clinical Epigenetics Year: 2021 Reference: Clin Epigenetics. 2021 Apr 23;13(1):88. doi: 10.1186/s13148-021-01070-0. Impact factor: Publication type: Paper in international publication Authors: Aaltonen, Lauri A; Anguita, Estefania; Arango, Diego; Bazzocco, Sarah; de Marcondes, Priscila Guimaraes; Dopeso, Higinio; Garcia-Vidal, Elia; Li, Jing; Maggio, Valentina; Mariadason, John M et al. DOI: 10.1186/s13148-021-01070-0
PMID: 31993962 Journal: Clinical & Translational Oncology Year: 2020 Reference: Clin Transl Oncol. 2020 Feb;22(2):256-269. doi: 10.1007/s12094-019-02285-7. Epub 2020 Jan 28. Impact factor: Publication type: Paper in international publication Authors: Arranz, J A; Beato, C; Chirivella, I; de-Velasco, G; Gonzalez-Del-Alba, A; Lainez, N; Lazaro, M; Mendez-Vidal, M J; Suarez, C; Valderrama, B P et al. DOI: 10.1007/s12094-019-02285-7
PMID: 31980684 Journal: Scientific Reports Year: 2020 Reference: Sci Rep. 2020 Jan 24;10(1):1159. doi: 10.1038/s41598-020-58197-y. Impact factor: Publication type: Paper in international publication Authors: Helm, Dominic; Jacobs-Cacha, Conxita; Lopez-Hellin, Joan; Meseguer, Anna; Moreso, Francesc J; Puig-Gay, Natalia; Rettel, Mandy; Savitski, Mikhail M; Sellares, Joana; Seron, Daniel et al. DOI: 10.1038/s41598-020-58197-y
PMID: 31840972 Journal: ACS Applied Materials & Interfaces Year: 2020 Reference: ACS Appl Mater Interfaces. 2020 Feb 5;12(5):5381-5388. doi: 10.1021/acsami.9b15803. Epub 2020 Jan 21. Impact factor: Publication type: Paper in international publication Authors: Abasolo, Ibane; Balta-Foix, Ricardo; Camara-Sanchez, Patricia; Gener, Petra; Jara, Jose Juan; Pesarrodona, Mireia; Pulido, Daniel; Royo, Miriam; Sanchez-Chardi, Alejandro; Sanchez-Garcia, Laura et al. DOI: 10.1021/acsami.9b15803
PMID: 31940096 Journal: Annals of Intensive Care Year: 2020 Reference: Ann Intensive Care. 2020 Jan 15;10(1):7. doi: 10.1186/s13613-020-0625-5. Impact factor: Publication type: Paper in international publication Authors: Baldira, Jaume; Chiscano, Luis; Comas, Inma; Cortes, Alejandro; Fabrega, Anna; Ferrer, Ricard; Ferrer-Costa, Roser; Gonzalez-Lopez, Juan Jose; Larrosa, Nieves; Ruiz-Rodriguez, Juan Carlos et al. DOI: 10.1186/s13613-020-0625-5
PMID: 29239718 Journal: JOURNAL OF GENERAL VIROLOGY Year: 2018 Reference: J Gen Virol. 2018 Jan;99(1):97-102. doi: 10.1099/jgv.0.000996. Epub 2017 Dec 14. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Chen, Qian; Esteban, Juan Ignacio; Esteban, Rafael; Garcia-Cehic, Damir; Gregori, Josep; Llorens, Meritxell; Nieto-Aponte, Leonardo; Ordeig, Laura; Perales, Celia et al. DOI: 10.1099/jgv.0.000996
PMID: 28988126 Journal: VIRUS RESEARCH Year: 2018 Reference: Virus Res. 2018 Jan 2;243:52-59. doi: 10.1016/j.virusres.2017.10.003. Epub 2017 Oct 4. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Esteban, Rafael; Godoy, Cristina; Gregori, Josep; Homs, Maria; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco; Ruiz, Alicia; Sopena, Sara; Tabernero, David et al. DOI: 10.1016/j.virusres.2017.10.003
Based on the study led by VHIR, a clinical trial has been approved for patients with locally advanced pancreatic cancer.
Vall d'Hebron participates in a project to develop innovative microsampling technology, making blood collection more accessible and patient-centered.
Researchers from all over Europe gathered to kick off the SPM4.0 project, an innovative Marie Curie Skłodowska (MSCA-DN) doctoral network that promotes the development of autonomous Scanning Probe Microscopy with AI.
