Skip to main content

Clinical Biochemistry, Drug Delivery & Therapy

The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.

With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.

In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.

Team

Yolanda Villena Ortiz

Yolanda Villena Ortiz

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Yolanda Villena Ortiz

Yolanda Villena Ortiz

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more

Projects

Role of Apolipoprotein A-Ib in the idiopathic nephrotic syndrome

IP: Concepció Jacobs Cachá
Collaborators: -
Funding agency: Fundació La Marató de TV3
Funding: 199966.31
Reference: 202017/10
Duration: 30/03/2021 - 31/12/2024

MIMIC-KeY - A KEY TO THE RATIONAL DESIGN OF EXTRACELLULAR VESICLES-MIMICKING NANOPARTICLES.

IP: Ibane Abasolo Olaortua
Collaborators: Joaquin Seras Franzoso, Guillem Pintos Morell, Zamira Vanessa Diaz Riascos, Simon Schwartz Navarro, Julia German Cortes
Funding agency: EUROPEAN COMMISSION
Funding: 457250
Reference: MIMIC-KEY_H2020-FETPROACT-2020
Duration: 01/06/2021 - 31/05/2025

Impact of COVID-19 on male reproductive health

IP: Melchor Carbonell Socias
Collaborators: Julio Herrero García, Nerea Maiz Elizaran, Anna Suy Franch, Maria del Pilar Reimundo Diaz-Fierros
Funding agency: Fundació La Marató de TV3
Funding: 49988.75
Reference: 202128-32
Duration: 20/10/2021 - 19/10/2024

EVERETT: Engineered mesenchymal stromal cell Extracellular Vesicles for immunomodulatory biotherapy and Enzyme REplacemenT Therapy

IP: Ibane Abasolo Olaortua
Collaborators: -
Funding agency: Agence Nationale de la Recherche
Funding: 0.01
Reference: EVERETT_ANR-BIOPNSE2020
Duration: 01/11/2022 - 31/10/2025

Publications

In-Host HEV Quasispecies Evolution Shows the Limits of Mutagenic Antiviral Treatments.

PMID: 38139013
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2023
Reference: Int J Mol Sci. 2023 Dec 6;24(24):17185. doi: 10.3390/ijms242417185.
Impact factor:
Publication type: Paper in international publication
Authors: Adombi, Caroline Melanie; Buti, Maria; Campos, Carolina; Colomer-Castell, Sergi; Cortese, Maria Francesca; Esteban, Juan Ignacio; Garcia-Cehic, Damir; Gregori, Josep; Ibanez-Lligona, Marta; Quer, Josep et al.
DOI: 10.3390/ijms242417185

Vitamin C deficiency in critically ill COVID-19 patients admitted to intensive care unit.

PMID: 38188336
Journal: Frontiers in Medicine
Year: 2023
Reference: Front Med (Lausanne). 2023 Dec 20;10:1301001. doi: 10.3389/fmed.2023.1301001. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Bajana, Ivan; Camos, Silvia; Chiscano-Camon, Luis; Ferrer, Ricard; Ferrer-Costa, Roser; Martin, Laura; Martin-Rodriguez, Cristina; Palmada, Clara; Perez-Carrasco, Marcos; Plata-Menchaca, Erika P et al.
DOI: 10.3389/fmed.2023.1301001

Blog

News

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

The European Rare Diseases Research Alliance (ERDERA) kicked off this September, with an estimated budget of 380 million euros and the aim of improving the lives of 30 million rare disease patients in Europe and beyond.

Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.