About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
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The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches.
Study of humoral responses against Epstein-Barr virus as a long-term prognostic factor in patients with MS.
Characterization of the immunological profiles associated with the different MS phenotypes.
Study of extracellular vesicles derived from CNS cells as prognostic biomarkers in patients with MS.
IP: Manuel Comabella Lopez
We focused on studying the impact of sexual hormones and the different reproductive stages of a woman's life on multiple sclerosis. As part of this project we have achieved the following publications:
1 - Menarche, pregnancies, and breastfeeding do not modify long-term prognosis in multiple sclerosis.
2 - Oral contraceptives do not modify the risk of a second attack and disability accrual in a prospective cohort of women with a clinically isolated syndrome and early multiple sclerosis.
3 - Menopause does not modify disability trajectories in a longitudinal cohort of women with clinically isolated syndrome and multiple sclerosis followed from disease onset.
4 - Menopause and multiple sclerosis: Influence on prognosis and role of disease-modifying drugs and hormonal replacement therapy.
IP: Mar Tintore Subirana, Luciana Midaglia Fernandez
Delve in the characterization of therapeutic targets identified by the group i.e. chitinase 3-like 1 and the NLRP3 inflammasome, for the development of new treatments in patients with MS.
Development of new humanized preclinical models of MS to investigate primary glial pathology, as well as the neuroprotective potential of new therapeutic agents: (i) generation of human glial chimeric mice with experimental autoimmune encephalomyelitis; (ii) transplantation of oligodendrocytes derived from MS patients into demyelinated human brain-slice cultures.
IP: Isabel Novoa Garcia Collaborators: Joaquim Vives Armengol, Anna Duarri Piqué, Eva Colas Ortega, Oriol Bestard Matamoros, Marta Rosal Fontana, Carmen Espejo Ruiz, Marielle Esteves Coelho, Juan Jose Gonzalez Lopez, Sheyla Pascual Martín, Alejandro Tomasello Weitz Funding agency: Instituto de Salud Carlos III Funding: 137460 Reference: PT23/00040 Duration: 01/01/2024 - 31/12/2026
IP: Alvaro Cobo Calvo Collaborators: - Funding agency: The Sumaira Foundation Funding: 25000 Reference: MOGAXON_SUMAIRA/COBO Duration: 06/03/2024 - 31/03/2026
IP: Carme Santoyo Medina Collaborators: Jaume Sastre Garriga, Ingrid Galán Cartaña, Montserrat Janer Cabo, M Jesus Arevalo Navines, Edwin Roger Meza Murillo, Xavier Montalban Gairín, Helena Llorente Blasco Funding agency: Societat Catalano_Balear de Fisioteràpia Funding: 3000 Reference: SCBF/2023/SANTOYO Duration: 18/12/2023 - 17/12/2026
IP: Begoña Benito Villabriga Collaborators: Carmen Escudero Iriarte, Laia Ventura i Expósito, Susana Otero Romero, Ibane Abasolo Olaortua, Ignacio Ferreira González, José Antonio Barrabés Riu, Carlos Nos Llopis, Pablo Velasco Puyó, Jose Fernando Rodríguez Palomares, María Rosario Pérez- Torres Lobato, Sunny Malhotra Sareen, Belen Perez Dueñas, Jaume Sastre Garriga, Joan López Hellin, Antonia Sambola Ayala, Jordi Rio Izquierdo, Nuria Rivas Gandara, Jordi Perez Rodon, Aroa Soriano Fernández, Manuel Comabella Lopez, Antonio Rodríguez Sinovas, Gisela Teixido Tura, Antonia Pijuan Domenech, Roser Ferrer Costa, Joaquin Seras Franzoso, Carmen Tur Gomez, Maria Cristina Díaz de Heredia Rubio, Laia Yañez Bisbe, Julia German Cortes, Maria Jose Pérez García, Miguel Segura Ginard, Diego Baranda Martínez-Abasca, Cristina Auger Acosta, Neus Bellera Gotarda, Herena Eixarch Ahufinger, M Mar Mañu Pereira, Deborah Pareto Onghena, Lorena Valero Arrese, Aitor Uribarri Gonzalez, Jordi Bañeras Rius, Alex Rovira Cañellas, Mar Tintore Subirana, Bruno García del Blanco, Maria Teresa Salcedo Allende, Marisol Ruiz Meana, Ana Belén Méndez Fernández, Xavier Montalban Gairín, Simon Schwartz Navarro, Anna Llort Sales, Carmen Espejo Ruiz, Raquel Hladun Alvaro, Angels Alcina Mila, Sandra Mancilla Zamora, Zamira Vanessa Diaz Riascos, Ana Zabalza de Torres, TACTIC: Explorando soluciones a los retos de salud mediante ciencia disruptiva, terapias avanzadas y medicina de sistemas, Marc Miquel Moltó Abad, Javier Inserte Igual, Luciana Midaglia Fernandez, Elizabeth Pando Rau, Gabriela Guillén Burrieza, Ana Laura Cazurro Gutierrez, David Gómez Andrés, Alvaro Cobo Calvo, Alvaro Calabuig Goena, Joaquin Castillo Justribo, Lydia Dux-Santoy Hurtado, Lucas Moreno Martín-Retortillo, TACTIC: Explorando soluciones a los retos de salud mediante ciencia disruptiva, terapias avanzadas y medicina de sistemas, Josep Roma Castanyer, Laura Dos Subirá, Nicolás Miguel Fissolo, Maria Nazarena Pizzi, Tian Tian, Fernanda Raquel Da Silva Andrade, Diana Fernandes de Rafael, Andrea Guala Funding agency: Instituto de Salud Carlos III Funding: 2494527.53 Reference: FORT23/00034 Duration: 01/01/2024 - 31/12/2027
PMID: 38101890 Journal: LANCET NEUROLOGY Year: 2024 Reference: Lancet Neurol. 2024 Jan;23(1):22-24. doi: 10.1016/S1474-4422(23)00459-3. Impact factor: Publication type: Paper in international publication Authors: Tintore, Mar; Tur, Carmen et al. DOI: 10.1016/S1474-4422(23)00459-3
PMID: 38165383 Journal: NEUROLOGY Year: 2024 Reference: Neurology. 2024 Jan 9;102(1):e207936. doi: 10.1212/WNL.0000000000207936. Epub 2023 Dec 13. Impact factor: Publication type: Editorail in international publication Authors: Rocca, Maria A; Tur, Carmen et al. DOI: 10.1212/WNL.0000000000207936
PMID: 38165378 Journal: NEUROLOGY Year: 2024 Reference: Neurology. 2024 Jan 9;102(1):e200805. doi: 10.1212/WNL.0000000000207805. Epub 2023 Dec 13. Impact factor: Publication type: Paper in international publication Authors: Arrambide, Georgina; Auger, Cristina; Bisecco, Alvino; Calderon, Willem; Capuano, Rocco; Castillo, Joaquin; Cerda-Fuertes, Nuria; Ciccarelli, Olga; Collorone, Sara; De Barros, Andrea et al. DOI: 10.1212/WNL.0000000000207805
PMID: 38168498 Journal: Scientific Reports Year: 2024 Reference: Sci Rep. 2024 Jan 2;14(1):122. doi: 10.1038/s41598-023-49299-4. Impact factor: Publication type: Paper in international publication Authors: Baker, Mike; Bernasconi, Corrado; Bove, Riley; Butzkueven, Helmut; Capezzuto, Luca; Giovannoni, Gavin; Gossens, Christian; Julian, Laura; Kappos, Ludwig; Kriara, Lito et al. DOI: 10.1038/s41598-023-49299-4
PMID: 36931808 Journal: LANCET NEUROLOGY Year: 2023 Reference: Lancet Neurol. 2023 Apr;22(4):350-366. doi: 10.1016/S1474-4422(22)00426-4. Impact factor: Publication type: Review in international publication Authors: Abdelnasser, Azza; Alroughani, Raed; Amato, Maria Pia; Bove, Riley; Ciplea, Andrea I; Dobson, Ruth; Fragoso, Yara; Hellwig, Kerstin; Houtchens, Maria; Jokubaitis, Vilija G et al. DOI: 10.1016/S1474-4422(22)00426-4
PMID: 36940621 Journal: NeuroImage-Clinical Year: 2023 Reference: Neuroimage Clin. 2023;38:103376. doi: 10.1016/j.nicl.2023.103376. Epub 2023 Mar 15. Impact factor: Publication type: Paper in international publication Authors: Alberich, Manel; Arrambide, Georgina; Auger, Cristina; Carbonell-Mirabent, Pere; Castillo, Joaquin; Cobo-Calvo, Alvaro; Coll, Llucia; Coll, Llucia; Comabella, Manuel; Galan, Ingrid et al. DOI: 10.1016/j.nicl.2023.103376
PMID: 36973075 Journal: Neurology-Neuroimmunology & Neuroinflammation Year: 2023 Reference: Neurol Neuroimmunol Neuroinflamm. 2023 Mar 27;10(3):e200100. doi: 10.1212/NXI.0000000000200100. Print 2023 May. Impact factor: Publication type: Paper in international publication Authors: Comabella, Manuel; Hurtado-Navarro, Laura; Malhotra, Sunny; Montalban, Xavier; Pappolla, Agustin; Pelegrin, Pablo; Rio, Jordi; Villar, Luisa M M et al. DOI: 10.1212/NXI.0000000000200100
PMID: 37012898 Journal: Multiple Sclerosis Journal Year: 2023 Reference: Mult Scler. 2023 May;29(6):719-730. doi: 10.1177/13524585231161494. Epub 2023 Apr 3. Impact factor: Publication type: Paper in international publication Authors: Aydemir, Aida; Borsi, Laszlo; Boyko, Alexey; Correale, Jorge; Edan, Gilles; Freedman, Mark S; Giovannoni, Gavin; Leist, Thomas; Montalban, Xavier; Rammohan, Kottil et al. DOI: 10.1177/13524585231161494
PMID: 36001711 Journal: NEW ENGLAND JOURNAL OF MEDICINE Year: 2022 Reference: N Engl J Med. 2022 Aug 25;387(8):704-714. doi: 10.1056/NEJMoa2201904. Impact factor: Publication type: Paper in international publication Authors: Adamczyk-Sowa, Monika; Alekseenko, Yuri; Alifirova, Valentina; Alvarez, Enrique; Alvarez, Enrique; Arefyeva, Elena; Arroyo Gonzalez, Rafael; Bakhtiyarova, Klara; Belova, Anna; Bernitsas, Evanthia et al. DOI: 10.1056/NEJMoa2201904
PMID: 34927702 Journal: REVISTA DE NEUROLOGIA Year: 2022 Reference: Rev Neurol. 2022 Jan 1;74(1):22-34. doi: 10.33588/rn.7401.2021163. Impact factor: 0.87 Publication type: Review in national publication Authors: Sepulveda, M; Arrambide, G; Cobo-Calvo, A et al. DOI: 10.33588/rn.7401.2021163
PMID: 34850641 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Jan;28(1):16-28. doi: 10.1177/13524585211059766. Epub 2021 Dec 1. Impact factor: 6.312 Publication type: Paper in international publication Authors: Coetzee, Timothy; Zaratin, Paola; Strum, Jon; Smith, Kathryn E; Thompson, Alan J; Carroll, William; Ciccarelli, Olga; Comi, Giancarlo; Cross, Anne; Donnelly, Alexis et al. DOI: 10.1177/13524585211059766
PMID: 33870790 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Jan;28(1):71-81. doi: 10.1177/13524585211010082. Epub 2021 Apr 19. Impact factor: 6.312 Publication type: Paper in international publication Authors: Pinteac, Rucsanda; Granziera, Cristina; Sastre-Garriga, Jaume; Benkert, Pascal; Auger, Cristina; Kuhle, Jens; Montalban, Xavier; Rovira, Alex; Fissolo, Nicolas; Pareto, Deborah et al. DOI: 10.1177/13524585211010082
PMID: 33625280 Journal: Multiple Sclerosis Journal Year: 2021 Reference: Mult Scler. 2021 Apr;27(5):661-662. doi: 10.1177/1352458520981309. Epub 2021 Feb 24. Impact factor: Publication type: Paper in international publication Authors: Tur, Carmen et al. DOI: 10.1177/1352458520981309
PMID: 33882422 Journal: NeuroImage-Clinical Year: 2021 Reference: Neuroimage Clin. 2021;30:102659. doi: 10.1016/j.nicl.2021.102659. Epub 2021 Apr 6. Impact factor: 4.881 Publication type: Paper in international publication Authors: Simoes, Jorge, Ruggieri, Serena, Schregel, Katharina, Ropele, Stefan, Rocca, Maria A, Gasperini, Claudio, Gallo, Antonio, Schoonheim, Menno M, Amann, Michael, Yiannakas, Marios et al. DOI: 10.1016/j.nicl.2021.102659
PMID: 34857668 Journal: Journal of NeuroInterventional Surgery Year: 2021 Reference: J Neurointerv Surg. 2021 Dec 2. pii: neurintsurg-2021-018241. doi: 10.1136/neurintsurg-2021-018241. Impact factor: 5.836 Publication type: Paper in international publication Authors: Olive-Gadea, Marta, Requena, Manuel, Diaz, Facundo, Boned, Sandra, Garcia-Tornel, Alvaro, Muchada, Marian, Deck, Matias, Lozano, Prudencio, Rodriguez-Villatoro, Noelia, Juega, Jesus et al. DOI: 10.1136/neurintsurg-2021-018241
PMID: 34859704 Journal: Multiple Sclerosis Journal Year: 2021 Reference: Mult Scler. 2021 Dec 3:13524585211061339. doi: 10.1177/13524585211061339. Impact factor: 6.312 Publication type: Paper in international publication Authors: Rovira, Alex, Corral, Juan Francisco, Auger, Cristina, Valverde, Sergi, Vidal-Jordana, Angela, Ng Wong, Yiken Karelys, Tintore, Mar, Pareto, Deborah, Aymerich, Francesc Xavier, Montalban, Xavier et al. DOI: 10.1177/13524585211061339
PMID: 31960250 Journal: NEUROLOGICAL SCIENCES Year: 2020 Reference: Neurol Sci. 2020 Jun;41(6):1513-1519. doi: 10.1007/s10072-019-04230-6. Epub 2020 Jan 20. Impact factor: Publication type: Paper in international publication Authors: Alonso Serena, Marina; Alonso, Ricardo; Alvez Pinheiro, Amelia; Balbuena, Maria E; Barboza, Andres G; Bestoso, Santiago; Blanche, Jorge; Blaya, Patricio A; Burgos, Marcos; Cabrera, Lorena M et al. DOI: 10.1007/s10072-019-04230-6
PMID: 31965896 Journal: Multiple Sclerosis Journal Year: 2020 Reference: Mult Scler. 2020 Apr;26(5):605-608. doi: 10.1177/1352458519888178. Epub 2020 Jan 22. Impact factor: Publication type: Paper in international publication Authors: Graves, Jennifer S; Montalban, Xavier et al. DOI: 10.1177/1352458519888178
PMID: 33424479 Journal: International journal of MS care Year: 2020 Reference: Int J MS Care. 2020 Nov-Dec;22(6):247-255. doi: 10.7224/1537-2073.2020-014. Epub 2020 Sep 14. Impact factor: 0 Publication type: Paper in international publication Authors: Coote, Susan, Santoyo-Medina, Carme, Kalron, Alon, Gunn, Hilary, Quinn, Gillian, Comber, Laura et al. DOI: 10.7224/1537-2073.2020-014
PMID: 31915118 Journal: Multiple Sclerosis and Related Disorders Year: 2020 Reference: Multiple Sclerosis and Related Disorders. 2020 Apr;39:101879. Impact factor: 2.889 Publication type: Paper in international publication Authors: Kos, Daphne, Ferdinand, Sofie, Duportail, Marijke, Eijssen, Isaline, Schouteden, Sofie, Kerkhofs, Lore, Jansa, Jelka, Fillo, Núria, Matuska, Kathleen, Beckerman, Heleen et al. DOI: 10.1016/j.msard.2019.101879
PMID: 31043474 Journal: NEUROLOGY Year: 2019 Reference: Neurology. 2019 May 28;92(22):e2538-e2549. doi: 10.1212/WNL.0000000000007572. Epub 2019 May 1. Impact factor: 8.689 Publication type: Paper in international publication Authors: Waubant, Emmanuelle, Banwell, Brenda, Wassmer, Evangeline, Sormani, Maria-Pia, Amato, Maria-Pia, Hintzen, Rogier, Krupp, Lauren, Rostasy, Kevin, Tenembaum, Silvia, Chitnis, Tanuja et al. DOI: 10.1212/WNL.0000000000007572
PMID: NOPMID0063 Journal: IEEE Access Year: 2019 Reference: IEEE Access. 2019;7:25171-84. doi: 10.1109/ACCESS.2019.2900198 Impact factor: 4.098 Publication type: Paper in international publication Authors: Salem, Mostafa, Valverde, Sergi, Cabezas, Mariano, Pareto Onghena, Deborah, Oliver, Arnau, Salvi, Joaquim, Rovira Cañellas, Alex, Llado, Xavier et al. DOI: 10.1109/ACCESS.2019.2900198
PMID: 31596725 Journal: JOURNAL OF MEDICAL INTERNET RESEARCH Year: 2019 Reference: J Med Internet Res. 2019 Oct 8;21(10):e16287. doi: 10.2196/16287. Impact factor: 4.945 Publication type: Letter or abstract Authors: Midaglia, Luciana, Mulero, Patricia, Montalban, Xavier, Graves, Jennifer, Hauser, Stephen L, Julian, Laura, Baker, Michael, Schadrack, Jan, Gossens, Christian, Scotland, Alf et al. DOI: 10.2196/16287
PMID: 31471961 Journal: JOURNAL OF MEDICAL INTERNET RESEARCH Year: 2019 Reference: J Med Internet Res. 2019 Aug 30;21(8):e14863. doi: 10.2196/14863. Impact factor: 4.945 Publication type: Paper in international publication Authors: Midaglia, Luciana, Mulero, Patricia, Montalban, Xavier, Graves, Jennifer, Hauser, Stephen L, Julian, Laura, Baker, Michael, Schadrack, Jan, Gossens, Christian, Scotland, Alf et al. DOI: 10.2196/14863
PMID: 29359174 Journal: Neurology-Neuroimmunology & Neuroinflammation Year: 2018 Reference: Neurol Neuroimmunol Neuroinflamm. 2018 Jan 17;5(2):e436. doi: 10.1212/NXI.0000000000000436. eCollection 2018 Mar. Impact factor: Publication type: Paper in international publication Authors: Alcaide-Leon, Paula; Bharatha, Aditya; Casserly, Courtney; Cybulsky, Kateryna; Hohol, Marika; Leung, General; Montalban, Xavier; Oh, Jiwon; Sankar, Stephanie; Selchen, Daniel et al. DOI: 10.1212/NXI.0000000000000436
PMID: 30367633 Journal: Journal of Neuroinflammation Year: 2018 Reference: J Neuroinflammation. 2018 Oct 26;15(1):296. doi: 10.1186/s12974-018-1336-9. Impact factor: 5.193 Publication type: Paper in international publication Authors: Montalban, Xavier, Malhotra, Sunny, Villar, Luisa M, Costa, Carme, Midaglia, Luciana, Cubedo, Marta, Medina, Silvia, Fissolo, Nicolas, Rio, Jordi, Castillo, Joaquin et al. DOI: 10.1186/s12974-018-1336-9
PMID: 29117789 Journal: Multiple Sclerosis Journal Year: 2018 Reference: Mult Scler. 2018 Oct;24(11):1507-1510. doi: 10.1177/1352458517739137. Epub 2017 Nov 9. Impact factor: 5.28 Publication type: Paper in international publication Authors: Malhotra, Sunny, Sorosina, Melissa, Rio, Jordi, Peroni, Silvia, Midaglia, Luciana, Villar, Luisa M, Alvarez-Cermeno, Jose C, Schroeder, Ina, Esposito, Federica, Clarelli, Ferdinando et al. DOI: 10.1177/1352458517739137
PMID: 28445084 Journal: Multiple Sclerosis Journal Year: 2018 Reference: Mult Scler. 2018 May;24(6):721-727. doi: 10.1177/1352458517707070. Epub 2017 Apr 26. Impact factor: 5.28 Publication type: Paper in international publication Authors: Huerga, Elena, Mitjana, Raquel, Auger, Cristina, Tintore, Mar, Rovira, Alex, Montalban, Xavier, Otero-Romero, Susana, Arrambide, Georgina, Pareto, Deborah, Vidal-Jordana, Angela et al. DOI: 10.1177/1352458517707070
PMID: 28093197 Journal: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS Year: 2017 Reference: Biochim Biophys Acta Gen Subj. 2017 Jun;1861(6):1507-1514. doi: 10.1016/j.bbagen.2017.01.012. Epub 2017 Jan 12. Impact factor: Publication type: Paper in international publication Authors: Alonso, J; Fdez-Gubieda, M L; Fernandez Barquin, L; Garcia-Prieto, A; Marcano, L; Muela, A; Munoz, D; Orue, I et al. DOI: 10.1016/j.bbagen.2017.01.012
PMID: 28289129 Journal: DEVELOPMENT Year: 2017 Reference: Development. 2017 Apr 15;144(8):1566-1577. doi: 10.1242/dev.138248. Epub 2017 Mar 13. Impact factor: Publication type: Paper in international publication Authors: Alberch, Jordi; Canals, Josep M; Chan, Susan; Edel, Michael J; Esgleas, Miriam; Garcia-Diaz Barriga, Gerardo; Giralt, Albert; Girault, Jean-Antoine; Guardia, Ines; Herranz, Cristina et al. DOI: 10.1242/dev.138248
PMID: 27456965 Journal: EUROPEAN RADIOLOGY Year: 2017 Reference: Eur Radiol. 2017 Apr;27(4):1361-1368. doi: 10.1007/s00330-016-4503-3. Epub 2016 Jul 25. Impact factor: 3.967 Publication type: Paper in international publication Authors: Aymerich, F X, Auger, C, Alcaide-Leon, P, Pareto, D, Corral, J F, Mitjana, R, Sastre-Garriga, J, Montalban, X, Rovira, A, Huerga, E et al. DOI: 10.1007/s00330-016-4503-3
PMID: 28063616 Journal: JOURNAL OF NEUROIMMUNOLOGY Year: 2017 Reference: J Neuroimmunol. 2017 Feb 15;303:62-65. doi: 10.1016/j.jneuroim.2016.12.006. Epub 2016 Dec 18. Impact factor: 2.536 Publication type: Paper in international publication Authors: Matute-Blanch, Clara, Rio, Jordi, Villar, Luisa M, Midaglia, Luciana, Malhotra, Sunny, Alvarez-Cermeno, Jose C, Vidal-Jordana, Angela, Montalban, Xavier, Comabella, Manuel et al. DOI: 10.1016/j.jneuroim.2016.12.006
PMID: 26362898 Journal: Multiple Sclerosis Journal Year: 2016 Reference: Mult Scler. 2016 Apr;22(4):533-43. doi: 10.1177/1352458515594440. Epub 2015 Sep 11. Impact factor: 4.822 Publication type: Paper in international publication Authors: Gugleta, K, Ecsedi, M, Lienert, C, Amato, M P, Baum, K, Buttmann, M, Bayas, A, Brassat, D, Brochet, B, Confavreux, C et al. DOI: 10.1177/1352458515594440
PMID: 26604134 Journal: HUMAN MOLECULAR GENETICS Year: 2016 Reference: Hum Mol Genet. 2016 Jan 15;25(2):308-16. doi: 10.1093/hmg/ddv473. Epub 2015 Nov 24. Impact factor: 5.985 Publication type: Paper in international publication Authors: Comabella, Manuel, Canto, Ester, Nurtdinov, Ramil, Rio, Jordi, Villar, Luisa M, Picon, Carmen, Castillo, Joaquin, Fissolo, Nicolas, Aymerich, Xavier, Auger, Cristina et al. DOI: 10.1093/hmg/ddv473
PMID: 26833969 Journal: HUMAN BRAIN MAPPING Year: 2016 Reference: Hum Brain Mapp. 2016 Apr;37(4):1627-44. doi: 10.1002/hbm.23125. Epub 2016 Feb 2. Impact factor: 4.962 Publication type: Paper in international publication Authors: Preziosa, Paolo, Rocca, Maria A, Pagani, Elisabetta, Stromillo, Maria Laura, Enzinger, Christian, Gallo, Antonio, Hulst, Hanneke E, Atzori, Matteo, Pareto, Deborah, Riccitelli, Gianna C et al. DOI: 10.1002/hbm.23125
PMID: 27439483 Journal: REVISTA DE NEUROLOGIA Year: 2016 Reference: Rev Neurol. 2016 Aug 16;63(4):145-50. Impact factor: 0.684 Publication type: Paper in national publication Authors: Montalban, X, Comabella, M, Rio, J, Rovira, A, Blanco, Y, Sainz, A, Perkal, H, Robles, R, Ramio-Torrenta, Ll, Diaz, R M et al. DOI:
PMID: 25392320 Journal: Multiple Sclerosis Journal Year: 2015 Reference: Mult Scler. 2015 May;21(6):780-5. doi: 10.1177/1352458514549401. Epub 2014 Nov 12. Impact factor: 4.863 Publication type: Paper in international publication Authors: Tintore, M, Tur, C, Perez-Miralles, F, Auger, C, Rio, J, Nos, C, Arrambide, G, Comabella, M, Galan, I, Castillo, J et al. DOI: 10.1177/1352458514549401
PMID: 25392330 Journal: Multiple Sclerosis Journal Year: 2015 Reference: Mult Scler. 2015 May;21(6):749-56. doi: 10.1177/1352458514556300. Epub 2014 Nov 12. Impact factor: 4.863 Publication type: Paper in international publication Authors: Rovira, A, Sastre-Garriga, J, Tur, C, Pareto, D, Vidal-Jordana, A, Auger, C, Rio, J, Huerga, E, Tintore, M, Montalban, X et al. DOI: 10.1177/1352458514556300
PMID: 26740917 Journal: NeuroImage-Clinical Year: 2015 Reference: Neuroimage Clin. 2015 Oct 28;9:640-7. doi: 10.1016/j.nicl.2015.10.012. eCollection 2015. Impact factor: 2.526 Publication type: Paper in international publication Authors: Valverde, Sergi, Oliver, Arnau, Roura, Eloy, Pareto, Deborah, Vilanova, Joan C, Ramio-Torrenta, Lluis, Sastre-Garriga, Jaume, Montalban, Xavier, Rovira, Alex, Llado, Xavier et al. DOI: 10.1016/j.nicl.2015.10.012
PMID: 26531701 Journal: JOURNAL OF NEUROIMMUNOLOGY Year: 2015 Reference: J Neuroimmunol. 2015 Nov 15;288:98-101. doi: 10.1016/j.jneuroim.2015.09.007. Epub 2015 Sep 25. Impact factor: 2.467 Publication type: Paper in international publication Authors: Negrotto, Laura, Canto, Ester, Tintore, Mar, Montalban, Xavier, Comabella, Manuel, Rio, Jordi et al. DOI: 10.1016/j.jneuroim.2015.09.007
PMID: 25732942 Journal: MED CLIN-BARCELONA Year: 2014 Reference: Med Clin (Barc). 2014 Dec;143 Suppl 3:3-6. doi: 10.1016/S0025-7753(15)30002-6. Impact factor: 1.252 Publication type: Review in national publication Authors: Rio, Jordi, Montalban, Xavier et al. DOI: 10.1016/S0025-7753(15)30002-6
PMID: 24824855 Journal: MOL IMAGING Year: 2014 Reference: Mol Imaging. 2014 May;13(3):1-12. Impact factor: 2.191 Publication type: Paper in international publication Authors: Logan, Jean, Kim, Sung Won, Pareto, Deborah, Telang, Frank, Wang, Gene-Jack, Fowler, Joanna S, Biegon, Anat et al. DOI:
PMID: 24748646 Journal: J MED GENET Year: 2014 Reference: J Med Genet. 2014 Jun;51(6):395-400. doi: 10.1136/jmedgenet-2014-102348. Epub 2014 Apr 19. Impact factor: 5.636 Publication type: Paper in international publication Authors: Nunez, Concepcion, Rio, Jordi, Fernandez-Arquero, Miguel, Arroyo, Rafael, Montalban, Xavier, Fernandez, Oscar, Oliver-Martos, Begona, Leyva, Laura, Comabella, Manuel, Urcelay, Elena et al. DOI: 10.1136/jmedgenet-2014-102348
PMID: 24793898 Journal: J NEUROIMMUNOL Year: 2014 Reference: J Neuroimmunol. 2014 Jul 15;272(1-2):51-5. doi: 10.1016/j.jneuroim.2014.04.007. Epub 2014 Apr 16. Impact factor: 2.786 Publication type: Paper in international publication Authors: Moreno, Montserrat, Negrotto, Laura, Rio, Jordi, Moubarak, Rana, Martin, Isabel, Bustamante, Marta F, Comella, Joan X, Vidal-Jordana, Angela, Perez-Boza, Jennifer, Montalban, Xavier et al. DOI: 10.1016/j.jneuroim.2014.04.007
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PhD student: Maria Arantza Dema Etxezarreta Director/s: Herena Eixarch Ahufinger, Carmen Espejo Ruiz University: Universitat Autònoma de Barcelona Year: 2023
PhD student: Luciana Midaglia Fernandez Director/s: Xavier Montalban Gairín, Jaume Sastre Garriga University: Year: 2023
PhD student: Ana Zabalza de Torres, Ana Zabalza de Torres Director/s: Mar Tintore Subirana, Georgina Arrambide García University: Universidad Autònoma de Barcelona Year: 2022
PhD student: Clara Matute Blanch Director/s: Manuel Comabella Lopez, Xavier Montalban Gairín University: Year: 2021
PhD student: Julia Enric Rubio Roca Director/s: Miguel Chillon Rodriguez, Xavier Montalban Gairín University: Year: 2020
PhD student: Laura Calvo Barreiro Director/s: Carmen Espejo Ruiz, Herena Eixarch Ahufinger, Xavier Montalban Gairín University: Universidad Autònoma de Barcelona Year: 2020
PhD student: Elia Gil Varea Director/s: Manuel Comabella Lopez, Xavier Montalban Gairín, Sunny Malhotra Sareen University: Universidad Autònoma de Barcelona Year: 2018
PhD student: Raúl Pelayo Vergara Director/s: Xavier Montalban Gairín University: Year: 2016
PhD student: Angela Vidal Jordana Director/s: Xavier Montalban Gairín, Jaume Sastre Garriga University: Universidad Autònoma de Barcelona Year: 2016
PhD student: Joaquin Castillo Justribo Director/s: Xavier Montalban Gairín, Jordi Rio Izquierdo University: Universidad Autònoma de Barcelona Year: 2016
PhD student: Jaume Sastre Garriga Director/s: Xavier Montalban Gairín University: Universidad Autònoma de Barcelona Year: 2015
PhD student: Sunny Malhotra Sareen Director/s: Manuel Comabella Lopez, Xavier Montalban Gairín University: Year: 2014
PhD student: M Jesus Arevalo Navines Director/s: Xavier Montalban Gairín University: Universidad Autònoma de Barcelona Year: 2014
PhD student: Manuel Comabella Lopez Director/s: Xavier Montalban Gairín University: Universidad Autònoma de Barcelona Year: 2013
PhD student: Carmen Tur Gomez, Carmen Tur Gomez Director/s: Xavier Montalban Gairín, Vicenç Fonollosa Pla University: Universidad Autònoma de Barcelona Year: 2012
PhD student: Carmen Espejo Ruiz Director/s: University: Universidad Autònoma de Barcelona Year: 2005
In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.
Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.
The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.
Simoa HD1 equipment
We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.
