Skip to main content

Clinical Neuroimmunology

The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches. 

Team

Xavier Montalban Gairín

Xavier Montalban Gairín

Head of group
Clinical Neuroimmunology
Read more
Jaume Sastre Garriga

Jaume Sastre Garriga

Main researcher
Clinical Neuroimmunology
Read more
Jordi Rio Izquierdo

Jordi Rio Izquierdo

Senior researcher
Clinical Neuroimmunology
Read more
Manuel Comabella Lopez

Manuel Comabella Lopez

Main researcher
Clinical Neuroimmunology
Read more
Mar Tintore Subirana

Mar Tintore Subirana

Main researcher
Clinical Neuroimmunology
Read more
Nicolás Miguel Fissolo

Nicolás Miguel Fissolo

Main researcher
Clinical Neuroimmunology
Read more
Xavier Montalban Gairín

Xavier Montalban Gairín

Head of group
Clinical Neuroimmunology
Read more
Jaume Sastre Garriga

Jaume Sastre Garriga

Main researcher
Clinical Neuroimmunology
Read more
Jordi Rio Izquierdo

Jordi Rio Izquierdo

Senior researcher
Clinical Neuroimmunology
Read more
Manuel Comabella Lopez

Manuel Comabella Lopez

Main researcher
Clinical Neuroimmunology
Read more
Mar Tintore Subirana

Mar Tintore Subirana

Main researcher
Clinical Neuroimmunology
Read more
Nicolás Miguel Fissolo

Nicolás Miguel Fissolo

Main researcher
Clinical Neuroimmunology
Read more

Research lines

Biomarkers of susceptibility, diagnosis and prognosis in MS (IV)

Study of humoral responses against Epstein-Barr virus as a long-term prognostic factor in patients with MS.


Characterization of the immunological profiles associated with the different MS phenotypes.


Study of extracellular vesicles derived from CNS cells as prognostic biomarkers in patients with MS.


IP: Comabella Lopez, Manuel

Multiple sclerosis and Gender

We focused on studying the impact of sexual hormones and the different reproductive stages of a woman's life on multiple sclerosis. As part of this project we have achieved the following publications:


1 - Menarche, pregnancies, and breastfeeding do not modify long-term prognosis in multiple sclerosis.

2 - Oral contraceptives do not modify the risk of a second attack and disability accrual in a prospective cohort of women with a clinically isolated syndrome and early multiple sclerosis.

3 - Menopause does not modify disability trajectories in a longitudinal cohort of women with clinically isolated syndrome and multiple sclerosis followed from disease onset.

4 - Menopause and multiple sclerosis: Influence on prognosis and role of disease-modifying drugs and hormonal replacement therapy.

IP: Tintore Subirana, Mar, Midaglia Fernandez, Luciana

Study of the pathogenesis of MS and search for new targets and/or therapeutic approaches (II)

Delve in the characterization of therapeutic targets identified by the group i.e. chitinase 3-like 1 and the NLRP3 inflammasome, for the development of new treatments in patients with MS.


Development of new humanized preclinical models of MS to investigate primary glial pathology, as well as the neuroprotective potential of new therapeutic agents: (i) generation of human glial chimeric mice with experimental autoimmune encephalomyelitis; (ii) transplantation of oligodendrocytes derived from MS patients into demyelinated human brain-slice cultures.

IP: Comabella Lopez, Manuel

Projects

Beca VHIR PhD

IP: Comabella Lopez, Manuel
Collaborators: Rodrigo Bosch, Sira, Perez Lasarte, Laia, Marín Ordovás, Elisa, Izquierdo Sans , Miriam
Funding agency: Fundació Institut de Recerca HUVH
Funding: 69188.74
Reference: VPHD/ELISA_M
Duration: 01/04/2023 - 31/03/2026

INHIBICION DE LA HDAC3 COMO TERAPIA PARA LESIONES MEDULARES Y ENFERMEDADES AUTOIMMUNES DEMIELINIZANTES

IP: Hervera Abad, Arnau
Collaborators: -
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 66612.39
Reference: PID2020-119769RA-I00
Duration: 01/01/2023 - 31/08/2024

Ministerio de Ciencia

x

IP: Montalban Gairín, Xavier
Collaborators: Hervera Abad, Arnau, Izquierdo Sans , Miriam
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 236350
Reference: RYC2021-033528-I
Duration: 01/01/2023 - 31/12/2027

Ministerio de Ciencia

MULTI-MOGAD – Multicenter longitudinal evaluation of neural and immune biomarkers in myelin oligodendrocyte glycoprotein antibodies (MOG-Ab)-associated disease

IP: Cobo Calvo, Alvaro
Collaborators: -
Funding agency: Fondation ARSEP
Funding: 20000
Reference: MULTI-MOGAD/ARSEP/2022
Duration: 15/12/2022 - 14/01/2024

Publications

Multiple sclerosis in 2023: beyond the boundaries.

PMID: 38101890
Journal: LANCET NEUROLOGY
Year: 2024
Reference: Lancet Neurol. 2024 Jan;23(1):22-24. doi: 10.1016/S1474-4422(23)00459-3.
Impact factor:
Publication type: Paper in international publication
Authors: Tintore, Mar; Tur, Carmen et al.
DOI: 10.1016/S1474-4422(23)00459-3

Progression Independent of Relapse Activity in Multiple Sclerosis.

PMID: 38165383
Journal: NEUROLOGY
Year: 2024
Reference: Neurology. 2024 Jan 9;102(1):e207936. doi: 10.1212/WNL.0000000000207936. Epub 2023 Dec 13.
Impact factor:
Publication type: Editorail in international publication
Authors: Rocca, Maria A; Tur, Carmen et al.
DOI: 10.1212/WNL.0000000000207936

Adding the Optic Nerve in Multiple Sclerosis Diagnostic Criteria.

PMID: 38165378
Journal: NEUROLOGY
Year: 2024
Reference: Neurology. 2024 Jan 9;102(1):e200805. doi: 10.1212/WNL.0000000000207805. Epub 2023 Dec 13.
Impact factor:
Publication type: Paper in international publication
Authors: Arrambide, Georgina; Auger, Cristina; Bisecco, Alvino; Calderon, Willem; Capuano, Rocco; Castillo, Joaquin; Cerda-Fuertes, Nuria; Ciccarelli, Olga; Collorone, Sara; De Barros, Andrea et al.
DOI: 10.1212/WNL.0000000000207805

Use of smartphone-based remote assessments of multiple sclerosis in Floodlight Open, a global, prospective, open-access study.

PMID: 38168498
Journal: Scientific Reports
Year: 2024
Reference: Sci Rep. 2024 Jan 2;14(1):122. doi: 10.1038/s41598-023-49299-4.
Impact factor:
Publication type: Paper in international publication
Authors: Baker, Mike; Bernasconi, Corrado; Bove, Riley; Butzkueven, Helmut; Capezzuto, Luca; Giovannoni, Gavin; Gossens, Christian; Julian, Laura; Kappos, Ludwig; Kriara, Lito et al.
DOI: 10.1038/s41598-023-49299-4

Family planning considerations in people with multiple sclerosis.

PMID: 36931808
Journal: LANCET NEUROLOGY
Year: 2023
Reference: Lancet Neurol. 2023 Apr;22(4):350-366. doi: 10.1016/S1474-4422(22)00426-4.
Impact factor:
Publication type: Review in international publication
Authors: Abdelnasser, Azza; Alroughani, Raed; Amato, Maria Pia; Bove, Riley; Ciplea, Andrea I; Dobson, Ruth; Fragoso, Yara; Hellwig, Kerstin; Houtchens, Maria; Jokubaitis, Vilija G et al.
DOI: 10.1016/S1474-4422(22)00426-4

Deciphering multiple sclerosis disability with deep learning attention maps on clinical MRI.

PMID: 36940621
Journal: NeuroImage-Clinical
Year: 2023
Reference: Neuroimage Clin. 2023;38:103376. doi: 10.1016/j.nicl.2023.103376. Epub 2023 Mar 15.
Impact factor:
Publication type: Paper in international publication
Authors: Alberich, Manel; Arrambide, Georgina; Auger, Cristina; Carbonell-Mirabent, Pere; Castillo, Joaquin; Cobo-Calvo, Alvaro; Coll, Llucia; Coll, Llucia; Comabella, Manuel; Galan, Ingrid et al.
DOI: 10.1016/j.nicl.2023.103376

Increased NLRP3 Inflammasome Activation and Pyroptosis in Patients With Multiple Sclerosis With Fingolimod Treatment Failure.

PMID: 36973075
Journal: Neurology-Neuroimmunology & Neuroinflammation
Year: 2023
Reference: Neurol Neuroimmunol Neuroinflamm. 2023 Mar 27;10(3):e200100. doi: 10.1212/NXI.0000000000200100. Print 2023 May.
Impact factor:
Publication type: Paper in international publication
Authors: Comabella, Manuel; Hurtado-Navarro, Laura; Malhotra, Sunny; Montalban, Xavier; Pappolla, Agustin; Pelegrin, Pablo; Rio, Jordi; Villar, Luisa M M et al.
DOI: 10.1212/NXI.0000000000200100

Long-term follow-up of patients with relapsing multiple sclerosis from the CLARITY/CLARITY Extension cohort of CLASSIC-MS: An ambispective study.

PMID: 37012898
Journal: Multiple Sclerosis Journal
Year: 2023
Reference: Mult Scler. 2023 May;29(6):719-730. doi: 10.1177/13524585231161494. Epub 2023 Apr 3.
Impact factor:
Publication type: Paper in international publication
Authors: Aydemir, Aida; Borsi, Laszlo; Boyko, Alexey; Correale, Jorge; Edan, Gilles; Freedman, Mark S; Giovannoni, Gavin; Leist, Thomas; Montalban, Xavier; Rammohan, Kottil et al.
DOI: 10.1177/13524585231161494

Ublituximab versus Teriflunomide in Relapsing Multiple Sclerosis.

PMID: 36001711
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2022
Reference: N Engl J Med. 2022 Aug 25;387(8):704-714. doi: 10.1056/NEJMoa2201904.
Impact factor:
Publication type: Paper in international publication
Authors: Adamczyk-Sowa, Monika; Alekseenko, Yuri; Alifirova, Valentina; Alvarez, Enrique; Alvarez, Enrique; Arefyeva, Elena; Arroyo Gonzalez, Rafael; Bakhtiyarova, Klara; Belova, Anna; Bernitsas, Evanthia et al.
DOI: 10.1056/NEJMoa2201904

[Epidemiology of neuromyelitis optica spectrum. New and old challenges].

PMID: 34927702
Journal: REVISTA DE NEUROLOGIA
Year: 2022
Reference: Rev Neurol. 2022 Jan 1;74(1):22-34. doi: 10.33588/rn.7401.2021163.
Impact factor: 0.87
Publication type: Review in national publication
Authors: Sepulveda, M; Arrambide, G; Cobo-Calvo, A et al.
DOI: 10.33588/rn.7401.2021163

Charting a global research strategy for progressive MS-An international progressive MS Alliance proposal.

PMID: 34850641
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Jan;28(1):16-28. doi: 10.1177/13524585211059766. Epub 2021 Dec 1.
Impact factor: 6.312
Publication type: Paper in international publication
Authors: Coetzee, Timothy; Zaratin, Paola; Strum, Jon; Smith, Kathryn E; Thompson, Alan J; Carroll, William; Ciccarelli, Olga; Comi, Giancarlo; Cross, Anne; Donnelly, Alexis et al.
DOI: 10.1177/13524585211059766

Impact of COVID-19 on multiple sclerosis care and management: Results from the European Committee for Treatment and Research in Multiple Sclerosis survey.

PMID: 33764197
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Jan;28(1):132-138. doi: 10.1177/13524585211005339. Epub 2021 Mar 25.
Impact factor: 6.312
Publication type: Paper in international publication
Authors: Portaccio, Emilio; Fonderico, Mattia; Hemmer, Bernhard; Derfuss, Tobias; Stankoff, Bruno; Selmaj, Krzysztof; Tintore, Mar; Amato, Maria Pia et al.
DOI: 10.1177/13524585211005339

Machine and deep learning in MS research are just powerful statistics - Yes.

PMID: 33625280
Journal: Multiple Sclerosis Journal
Year: 2021
Reference: Mult Scler. 2021 Apr;27(5):661-662. doi: 10.1177/1352458520981309. Epub 2021 Feb 24.
Impact factor:
Publication type: Paper in international publication
Authors: Tur, Carmen et al.
DOI: 10.1177/1352458520981309

Development and evaluation of a manual segmentation protocol for deep grey matter in multiple sclerosis: Towards accelerated semi-automated references.

PMID: 33882422
Journal: NeuroImage-Clinical
Year: 2021
Reference: Neuroimage Clin. 2021;30:102659. doi: 10.1016/j.nicl.2021.102659. Epub 2021 Apr 6.
Impact factor: 4.881
Publication type: Paper in international publication
Authors: Simoes, Jorge, Ruggieri, Serena, Schregel, Katharina, Ropele, Stefan, Rocca, Maria A, Gasperini, Claudio, Gallo, Antonio, Schoonheim, Menno M, Amann, Michael, Yiannakas, Marios et al.
DOI: 10.1016/j.nicl.2021.102659

Systematic CT perfusion acquisition in acute stroke increases vascular occlusion detection and thrombectomy rates.

PMID: 34857668
Journal: Journal of NeuroInterventional Surgery
Year: 2021
Reference: J Neurointerv Surg. 2021 Dec 2. pii: neurintsurg-2021-018241. doi: 10.1136/neurintsurg-2021-018241.
Impact factor: 5.836
Publication type: Paper in international publication
Authors: Olive-Gadea, Marta, Requena, Manuel, Diaz, Facundo, Boned, Sandra, Garcia-Tornel, Alvaro, Muchada, Marian, Deck, Matias, Lozano, Prudencio, Rodriguez-Villatoro, Noelia, Juega, Jesus et al.
DOI: 10.1136/neurintsurg-2021-018241

Assessment of automatic decision-support systems for detecting active T2 lesions in multiple sclerosis patients.

PMID: 34859704
Journal: Multiple Sclerosis Journal
Year: 2021
Reference: Mult Scler. 2021 Dec 3:13524585211061339. doi: 10.1177/13524585211061339.
Impact factor: 6.312
Publication type: Paper in international publication
Authors: Rovira, Alex, Corral, Juan Francisco, Auger, Cristina, Valverde, Sergi, Vidal-Jordana, Angela, Ng Wong, Yiken Karelys, Tintore, Mar, Pareto, Deborah, Aymerich, Francesc Xavier, Montalban, Xavier et al.
DOI: 10.1177/13524585211061339

Multiple sclerosis and neuromyelitis optica spectrum disorders in Argentina: comparing baseline data from the Argentinean MS Registry (RelevarEM).

PMID: 31960250
Journal: NEUROLOGICAL SCIENCES
Year: 2020
Reference: Neurol Sci. 2020 Jun;41(6):1513-1519. doi: 10.1007/s10072-019-04230-6. Epub 2020 Jan 20.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso Serena, Marina; Alonso, Ricardo; Alvez Pinheiro, Amelia; Balbuena, Maria E; Barboza, Andres G; Bestoso, Santiago; Blanche, Jorge; Blaya, Patricio A; Burgos, Marcos; Cabrera, Lorena M et al.
DOI: 10.1007/s10072-019-04230-6

Biosensors to monitor MS activity.

PMID: 31965896
Journal: Multiple Sclerosis Journal
Year: 2020
Reference: Mult Scler. 2020 Apr;26(5):605-608. doi: 10.1177/1352458519888178. Epub 2020 Jan 22.
Impact factor:
Publication type: Paper in international publication
Authors: Graves, Jennifer S; Montalban, Xavier et al.
DOI: 10.1177/1352458519888178

Falls in People with Multiple Sclerosis: Risk Identification, Intervention, and Future Directions.

PMID: 33424479
Journal: International journal of MS care
Year: 2020
Reference: Int J MS Care. 2020 Nov-Dec;22(6):247-255. doi: 10.7224/1537-2073.2020-014. Epub 2020 Sep 14.
Impact factor: 0
Publication type: Paper in international publication
Authors: Coote, Susan, Santoyo-Medina, Carme, Kalron, Alon, Gunn, Hilary, Quinn, Gillian, Comber, Laura et al.
DOI: 10.7224/1537-2073.2020-014

Assessing life balance of European people with multiple sclerosis: A multicenter clinimetric study within the RIMS network.

PMID: 31915118
Journal: Multiple Sclerosis and Related Disorders
Year: 2020
Reference: Multiple Sclerosis and Related Disorders. 2020 Apr;39:101879.
Impact factor: 2.889
Publication type: Paper in international publication
Authors: Kos, Daphne, Ferdinand, Sofie, Duportail, Marijke, Eijssen, Isaline, Schouteden, Sofie, Kerkhofs, Lore, Jansa, Jelka, Fillo, Núria, Matuska, Kathleen, Beckerman, Heleen et al.
DOI: 10.1016/j.msard.2019.101879

Clinical trials of disease-modifying agents in pediatric MS: Opportunities, challenges, and recommendations from the IPMSSG.

PMID: 31043474
Journal: NEUROLOGY
Year: 2019
Reference: Neurology. 2019 May 28;92(22):e2538-e2549. doi: 10.1212/WNL.0000000000007572. Epub 2019 May 1.
Impact factor: 8.689
Publication type: Paper in international publication
Authors: Waubant, Emmanuelle, Banwell, Brenda, Wassmer, Evangeline, Sormani, Maria-Pia, Amato, Maria-Pia, Hintzen, Rogier, Krupp, Lauren, Rostasy, Kevin, Tenembaum, Silvia, Chitnis, Tanuja et al.
DOI: 10.1212/WNL.0000000000007572

Multiple Sclerosis Lesion Synthesis in MRI Using an Encoder-Decoder U-NET

PMID: NOPMID0063
Journal: IEEE Access
Year: 2019
Reference: IEEE Access. 2019;7:25171-84. doi: 10.1109/ACCESS.2019.2900198
Impact factor: 4.098
Publication type: Paper in international publication
Authors: Salem, Mostafa, Valverde, Sergi, Cabezas, Mariano, Pareto Onghena, Deborah, Oliver, Arnau, Salvi, Joaquim, Rovira Cañellas, Alex, Llado, Xavier et al.
DOI: 10.1109/ACCESS.2019.2900198

Correction: Adherence and Satisfaction of Smartphone- and Smartwatch-Based Remote Active Testing and Passive Monitoring in People With Multiple Sclerosis: Nonrandomized Interventional Feasibility Study.

PMID: 31596725
Journal: JOURNAL OF MEDICAL INTERNET RESEARCH
Year: 2019
Reference: J Med Internet Res. 2019 Oct 8;21(10):e16287. doi: 10.2196/16287.
Impact factor: 4.945
Publication type: Letter or abstract
Authors: Midaglia, Luciana, Mulero, Patricia, Montalban, Xavier, Graves, Jennifer, Hauser, Stephen L, Julian, Laura, Baker, Michael, Schadrack, Jan, Gossens, Christian, Scotland, Alf et al.
DOI: 10.2196/16287

Adherence and Satisfaction of Smartphone- and Smartwatch-Based Remote Active Testing and Passive Monitoring in People With Multiple Sclerosis: Nonrandomized Interventional Feasibility Study.

PMID: 31471961
Journal: JOURNAL OF MEDICAL INTERNET RESEARCH
Year: 2019
Reference: J Med Internet Res. 2019 Aug 30;21(8):e14863. doi: 10.2196/14863.
Impact factor: 4.945
Publication type: Paper in international publication
Authors: Midaglia, Luciana, Mulero, Patricia, Montalban, Xavier, Graves, Jennifer, Hauser, Stephen L, Julian, Laura, Baker, Michael, Schadrack, Jan, Gossens, Christian, Scotland, Alf et al.
DOI: 10.2196/14863

Quantitative spinal cord MRI in radiologically isolated syndrome.

PMID: 29359174
Journal: Neurology-Neuroimmunology & Neuroinflammation
Year: 2018
Reference: Neurol Neuroimmunol Neuroinflamm. 2018 Jan 17;5(2):e436. doi: 10.1212/NXI.0000000000000436. eCollection 2018 Mar.
Impact factor:
Publication type: Paper in international publication
Authors: Alcaide-Leon, Paula; Bharatha, Aditya; Casserly, Courtney; Cybulsky, Kateryna; Hohol, Marika; Leung, General; Montalban, Xavier; Oh, Jiwon; Sankar, Stephanie; Selchen, Daniel et al.
DOI: 10.1212/NXI.0000000000000436

Circulating EZH2-positive T cells are decreased in multiple sclerosis patients.

PMID: 30367633
Journal: Journal of Neuroinflammation
Year: 2018
Reference: J Neuroinflammation. 2018 Oct 26;15(1):296. doi: 10.1186/s12974-018-1336-9.
Impact factor: 5.193
Publication type: Paper in international publication
Authors: Montalban, Xavier, Malhotra, Sunny, Villar, Luisa M, Costa, Carme, Midaglia, Luciana, Cubedo, Marta, Medina, Silvia, Fissolo, Nicolas, Rio, Jordi, Castillo, Joaquin et al.
DOI: 10.1186/s12974-018-1336-9

NLRP3 polymorphisms and response to interferon-beta in multiple sclerosis patients.

PMID: 29117789
Journal: Multiple Sclerosis Journal
Year: 2018
Reference: Mult Scler. 2018 Oct;24(11):1507-1510. doi: 10.1177/1352458517739137. Epub 2017 Nov 9.
Impact factor: 5.28
Publication type: Paper in international publication
Authors: Malhotra, Sunny, Sorosina, Melissa, Rio, Jordi, Peroni, Silvia, Midaglia, Luciana, Villar, Luisa M, Alvarez-Cermeno, Jose C, Schroeder, Ina, Esposito, Federica, Clarelli, Ferdinando et al.
DOI: 10.1177/1352458517739137

Brain atrophy 15 years after CIS: Baseline and follow-up clinico-radiological correlations.

PMID: 28445084
Journal: Multiple Sclerosis Journal
Year: 2018
Reference: Mult Scler. 2018 May;24(6):721-727. doi: 10.1177/1352458517707070. Epub 2017 Apr 26.
Impact factor: 5.28
Publication type: Paper in international publication
Authors: Huerga, Elena, Mitjana, Raquel, Auger, Cristina, Tintore, Mar, Rovira, Alex, Montalban, Xavier, Otero-Romero, Susana, Arrambide, Georgina, Pareto, Deborah, Vidal-Jordana, Angela et al.
DOI: 10.1177/1352458517707070

Influence of the bacterial growth phase on the magnetic properties of magnetosomes synthesized by Magnetospirillum gryphiswaldense.

PMID: 28093197
Journal: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Year: 2017
Reference: Biochim Biophys Acta Gen Subj. 2017 Jun;1861(6):1507-1514. doi: 10.1016/j.bbagen.2017.01.012. Epub 2017 Jan 12.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, J; Fdez-Gubieda, M L; Fernandez Barquin, L; Garcia-Prieto, A; Marcano, L; Muela, A; Munoz, D; Orue, I et al.
DOI: 10.1016/j.bbagen.2017.01.012

Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons.

PMID: 28289129
Journal: DEVELOPMENT
Year: 2017
Reference: Development. 2017 Apr 15;144(8):1566-1577. doi: 10.1242/dev.138248. Epub 2017 Mar 13.
Impact factor:
Publication type: Paper in international publication
Authors: Alberch, Jordi; Canals, Josep M; Chan, Susan; Edel, Michael J; Esgleas, Miriam; Garcia-Diaz Barriga, Gerardo; Giralt, Albert; Girault, Jean-Antoine; Guardia, Ines; Herranz, Cristina et al.
DOI: 10.1242/dev.138248

Comparison between gadolinium-enhanced 2D T1-weighted gradient-echo and spin-echo sequences in the detection of active multiple sclerosis lesions on 3.0T MRI.

PMID: 27456965
Journal: EUROPEAN RADIOLOGY
Year: 2017
Reference: Eur Radiol. 2017 Apr;27(4):1361-1368. doi: 10.1007/s00330-016-4503-3. Epub 2016 Jul 25.
Impact factor: 3.967
Publication type: Paper in international publication
Authors: Aymerich, F X, Auger, C, Alcaide-Leon, P, Pareto, D, Corral, J F, Mitjana, R, Sastre-Garriga, J, Montalban, X, Rovira, A, Huerga, E et al.
DOI: 10.1007/s00330-016-4503-3

Chitinase 3-like 1 is associated with the response to interferon-beta treatment in multiple sclerosis.

PMID: 28063616
Journal: JOURNAL OF NEUROIMMUNOLOGY
Year: 2017
Reference: J Neuroimmunol. 2017 Feb 15;303:62-65. doi: 10.1016/j.jneuroim.2016.12.006. Epub 2016 Dec 18.
Impact factor: 2.536
Publication type: Paper in international publication
Authors: Matute-Blanch, Clara, Rio, Jordi, Villar, Luisa M, Midaglia, Luciana, Malhotra, Sunny, Alvarez-Cermeno, Jose C, Vidal-Jordana, Angela, Montalban, Xavier, Comabella, Manuel et al.
DOI: 10.1016/j.jneuroim.2016.12.006

A 10-year follow-up of the European multicenter trial of interferon beta-1b in secondary-progressive multiple sclerosis.

PMID: 26362898
Journal: Multiple Sclerosis Journal
Year: 2016
Reference: Mult Scler. 2016 Apr;22(4):533-43. doi: 10.1177/1352458515594440. Epub 2015 Sep 11.
Impact factor: 4.822
Publication type: Paper in international publication
Authors: Gugleta, K, Ecsedi, M, Lienert, C, Amato, M P, Baum, K, Buttmann, M, Bayas, A, Brassat, D, Brochet, B, Confavreux, C et al.
DOI: 10.1177/1352458515594440

Structural MRI correlates of cognitive impairment in patients with multiple sclerosis: A Multicenter Study.

PMID: 26833969
Journal: HUMAN BRAIN MAPPING
Year: 2016
Reference: Hum Brain Mapp. 2016 Apr;37(4):1627-44. doi: 10.1002/hbm.23125. Epub 2016 Feb 2.
Impact factor: 4.962
Publication type: Paper in international publication
Authors: Preziosa, Paolo, Rocca, Maria A, Pagani, Elisabetta, Stromillo, Maria Laura, Enzinger, Christian, Gallo, Antonio, Hulst, Hanneke E, Atzori, Matteo, Pareto, Deborah, Riccitelli, Gianna C et al.
DOI: 10.1002/hbm.23125

MRI phenotypes with high neurodegeneration are associated with peripheral blood B-cell changes.

PMID: 26604134
Journal: HUMAN MOLECULAR GENETICS
Year: 2016
Reference: Hum Mol Genet. 2016 Jan 15;25(2):308-16. doi: 10.1093/hmg/ddv473. Epub 2015 Nov 24.
Impact factor: 5.985
Publication type: Paper in international publication
Authors: Comabella, Manuel, Canto, Ester, Nurtdinov, Ramil, Rio, Jordi, Villar, Luisa M, Picon, Carmen, Castillo, Joaquin, Fissolo, Nicolas, Aymerich, Xavier, Auger, Cristina et al.
DOI: 10.1093/hmg/ddv473

[Response to treatment with interferon beta in patients with multiple sclerosis. Validation of the Rio Score].

PMID: 27439483
Journal: REVISTA DE NEUROLOGIA
Year: 2016
Reference: Rev Neurol. 2016 Aug 16;63(4):145-50.
Impact factor: 0.684
Publication type: Paper in national publication
Authors: Montalban, X, Comabella, M, Rio, J, Rovira, A, Blanco, Y, Sainz, A, Perkal, H, Robles, R, Ramio-Torrenta, Ll, Diaz, R M et al.
DOI:

Significant clinical worsening after natalizumab withdrawal: Predictive factors.

PMID: 25392320
Journal: Multiple Sclerosis Journal
Year: 2015
Reference: Mult Scler. 2015 May;21(6):780-5. doi: 10.1177/1352458514549401. Epub 2014 Nov 12.
Impact factor: 4.863
Publication type: Paper in international publication
Authors: Tintore, M, Tur, C, Perez-Miralles, F, Auger, C, Rio, J, Nos, C, Arrambide, G, Comabella, M, Galan, I, Castillo, J et al.
DOI: 10.1177/1352458514549401

Brain atrophy in natalizumab-treated patients: A 3-year follow-up.

PMID: 25392330
Journal: Multiple Sclerosis Journal
Year: 2015
Reference: Mult Scler. 2015 May;21(6):749-56. doi: 10.1177/1352458514556300. Epub 2014 Nov 12.
Impact factor: 4.863
Publication type: Paper in international publication
Authors: Rovira, A, Sastre-Garriga, J, Tur, C, Pareto, D, Vidal-Jordana, A, Auger, C, Rio, J, Huerga, E, Tintore, M, Montalban, X et al.
DOI: 10.1177/1352458514556300

Quantifying brain tissue volume in multiple sclerosis with automated lesion segmentation and filling.

PMID: 26740917
Journal: NeuroImage-Clinical
Year: 2015
Reference: Neuroimage Clin. 2015 Oct 28;9:640-7. doi: 10.1016/j.nicl.2015.10.012. eCollection 2015.
Impact factor: 2.526
Publication type: Paper in international publication
Authors: Valverde, Sergi, Oliver, Arnau, Roura, Eloy, Pareto, Deborah, Vilanova, Joan C, Ramio-Torrenta, Lluis, Sastre-Garriga, Jaume, Montalban, Xavier, Rovira, Alex, Llado, Xavier et al.
DOI: 10.1016/j.nicl.2015.10.012

Peripheral blood non-MAIT CD8+CD161hi cells are decreased in relapsing-remitting multiple sclerosis patients treated with interferon beta.

PMID: 26531701
Journal: JOURNAL OF NEUROIMMUNOLOGY
Year: 2015
Reference: J Neuroimmunol. 2015 Nov 15;288:98-101. doi: 10.1016/j.jneuroim.2015.09.007. Epub 2015 Sep 25.
Impact factor: 2.467
Publication type: Paper in international publication
Authors: Negrotto, Laura, Canto, Ester, Tintore, Mar, Montalban, Xavier, Comabella, Manuel, Rio, Jordi et al.
DOI: 10.1016/j.jneuroim.2015.09.007

[Current description of multiple sclerosis].

PMID: 25732942
Journal: MED CLIN-BARCELONA
Year: 2014
Reference: Med Clin (Barc). 2014 Dec;143 Suppl 3:3-6. doi: 10.1016/S0025-7753(15)30002-6.
Impact factor: 1.252
Publication type: Review in national publication
Authors: Rio, Jordi, Montalban, Xavier et al.
DOI: 10.1016/S0025-7753(15)30002-6

Kinetic analysis of [11C]vorozole binding in the human brain with positron emission tomography.

PMID: 24824855
Journal: MOL IMAGING
Year: 2014
Reference: Mol Imaging. 2014 May;13(3):1-12.
Impact factor: 2.191
Publication type: Paper in international publication
Authors: Logan, Jean, Kim, Sung Won, Pareto, Deborah, Telang, Frank, Wang, Gene-Jack, Fowler, Joanna S, Biegon, Anat et al.
DOI:

HLA alleles as biomarkers of high-titre neutralising antibodies to interferon-beta therapy in multiple sclerosis.

PMID: 24748646
Journal: J MED GENET
Year: 2014
Reference: J Med Genet. 2014 Jun;51(6):395-400. doi: 10.1136/jmedgenet-2014-102348. Epub 2014 Apr 19.
Impact factor: 5.636
Publication type: Paper in international publication
Authors: Nunez, Concepcion, Rio, Jordi, Fernandez-Arquero, Miguel, Arroyo, Rafael, Montalban, Xavier, Fernandez, Oscar, Oliver-Martos, Begona, Leyva, Laura, Comabella, Manuel, Urcelay, Elena et al.
DOI: 10.1136/jmedgenet-2014-102348

Activation-induced cell death in T lymphocytes from multiple sclerosis patients.

PMID: 24793898
Journal: J NEUROIMMUNOL
Year: 2014
Reference: J Neuroimmunol. 2014 Jul 15;272(1-2):51-5. doi: 10.1016/j.jneuroim.2014.04.007. Epub 2014 Apr 16.
Impact factor: 2.786
Publication type: Paper in international publication
Authors: Moreno, Montserrat, Negrotto, Laura, Rio, Jordi, Moubarak, Rana, Martin, Isabel, Bustamante, Marta F, Comella, Joan X, Vidal-Jordana, Angela, Perez-Boza, Jennifer, Montalban, Xavier et al.
DOI: 10.1016/j.jneuroim.2014.04.007

In vivo imaging of brain aromatase in female baboons: [11C]vorozole kinetics and effect of the menstrual cycle.

PMID: 24447618
Journal: Molecular Imaging
Year: 2013
Reference: Mol Imaging. 2013 Nov-Dec;12(8). doi: 10.2310/7290.2013.00068.
Impact factor: 3.408
Publication type: Paper in international publication
Authors: Pareto, Deborah, Biegon, Anat, Alexoff, David, Carter, Pauline, Shea, Coreen, Muench, Lisa, Xu, Youwen, Fowler, Joanna S, Kim, Sunny W, Logan, Jean et al.
DOI: 10.2310/7290.2013.00068

Optimization of [(11)C]raclopride positron emission tomographic rat studies: comparison of methods for image quantification.

PMID: 23651503
Journal: Molecular Imaging
Year: 2013
Reference: Mol Imaging. 2013 Jun;12(4):257-62.
Impact factor: 3.408
Publication type: Paper in international publication
Authors: Pareto, Deborah, Ruiz, Alba, Gispert, Juan Domingo, Millan, Olga, Torrent, Elia, Farre, Magi, Abasolo, Ibane, Llop, Jordi et al.
DOI:

Clinical impact of early brain atrophy in clinically isolated syndromes.

PMID: 23652215
Journal: Multiple Sclerosis Journal
Year: 2013
Reference: Mult Scler. 2013 Dec;19(14):1878-86. doi: 10.1177/1352458513488231. Epub 2013 May 7.
Impact factor: 4.472
Publication type: Paper in international publication
Authors: Montalban, X, Rovira, A, Huerga, E, Auger, C, Perez-Miralles, F, Sastre-Garriga, J, Tintore, M, Arrambide, G, Nos, C, Perkal, H et al.
DOI: 10.1177/1352458513488231

Baseline gene expression signatures in monocytes from multiple sclerosis patients treated with interferon-beta.

PMID: 23637780
Journal: PLoS One
Year: 2013
Reference: PLoS One. 2013 Apr 18;8(4):e60994. doi: 10.1371/journal.pone.0060994. Print 2013.
Impact factor: 3.73
Publication type: Paper in international publication
Authors: Montalban, Xavier, Bustamante, Marta F, Nurtdinov, Ramil N, Rio, Jordi, Comabella, Manuel et al.
DOI: 10.1371/journal.pone.0060994

In vivo molecular imaging of the GABA/benzodiazepine receptor complex in the aged rat brain.

PMID: 21272959
Journal: NEUROBIOLOGY OF AGING
Year: 2012
Reference: Neurobiol Aging. 2012 Jul;33(7):1457-65. doi: 10.1016/j.neurobiolaging.2010.12.006. Epub 2011 Jan 26.
Impact factor: 6.189
Publication type: Paper in international publication
Authors: Abad, Sergio, Jimenez, Xavier, Figueiras, Francisca P, Popota, Foteini, Ruiz, Alba, Flotats, Nuria, Fernandez, Francisco J, Rocha, Milagros, Rovira, Mariana, Victor, Victor M et al.
DOI: 10.1016/j.neurobiolaging.2010.12.006

Which walking capacity tests to use in multiple sclerosis? A multicentre study providing the basis for a core set.

PMID: 21952098
Journal: Multiple Sclerosis Journal
Year: 2012
Reference: Mult Scler. 2012 Mar;18(3):364-71. doi: 10.1177/1352458511420598. Epub 2011 Sep 27.
Impact factor: 4.255
Publication type: Clinical guide
Authors: Gijbels, Domien, Dalgas, Ulrik, Romberg, Anders, de Groot, Vincent, Bethoux, Francois, Vaney, Claude, Gebara, Benoit, Medina, Carme Santoyo, Maamagi, Heigo, Rasova, Kamila et al.
DOI: 10.1177/1352458511420598

Effect of time of day on walking capacity and self-reported fatigue in persons with multiple sclerosis: a multi-center trial.

PMID: 21969239
Journal: Multiple Sclerosis Journal
Year: 2012
Reference: Mult Scler. 2012 Mar;18(3):351-7. doi: 10.1177/1352458511419881. Epub 2011 Oct 3.
Impact factor: 4.255
Publication type: Paper in international publication
Authors: Gijbels, D, Romberg, A, Santoyo, C, Gebara, B, de Noordhout, B Maertens, Knuts, K, Bethoux, F, de Groot, V, Vaney, C, Dalgas, U et al.
DOI: 10.1177/1352458511419881

Whole-body vibration training for patients with neurodegenerative disease.

PMID: 22336858
Journal: Cochrane Database of Systematic Reviews
Year: 2012
Reference: Cochrane Database Syst Rev. 2012 Feb 15;(2):CD009097. doi: 10.1002/14651858.CD009097.pub2.
Impact factor: 5.912
Publication type: Review in national publication
Authors: Roque i Figuls, Marta, Romero-Rodriguez, Daniel, Bonfill Cosp, Xavier, Santoyo Medina, Carme, Fort Vanmeerhaeghe, Azahara, Rigau Comas, David, Sitja Rabert, Merce et al.
DOI: 10.1002/14651858.CD009097.pub2

Interferon Beta-1b for the Treatment of Primary Progressive Multiple Sclerosis: Five-Year Clinical Trial Follow-up.

PMID: 22084124
Journal: ARCHIVES OF NEUROLOGY
Year: 2011
Reference: Arch Neurol. 2011 Nov;68(11):1421-7.
Impact factor: 7.108
Publication type: Paper in international publication
Authors: Tur, Carmen, Montalban, Xavier, Tintore, Mar, Nos, Carlos, Rio, Jordi, Aymerich, Francesc Xavier, Brieva, Luis, Tellez, Nieves, Perkal, Hector, Comabella, Manuel et al.
DOI: 10.1001/archneurol.2011.241

Implication of the toll-like receptor 4 pathway in the response to interferon-beta in multiple sclerosis.

PMID: 22028223
Journal: ANNALS OF NEUROLOGY
Year: 2011
Reference: Ann Neurol. 2011 Oct;70(4):634-45. doi: 10.1002/ana.22511.
Impact factor: 10.746
Publication type: Paper in international publication
Authors: Bustamante, Marta F, Fissolo, Nicolas, Rio, Jordi, Espejo, Carmen, Costa, Carme, Mansilla, Maria Jose, Lizasoain, Ignacio, Angeles Moro, Maria, Carmen Edo, Mari, Comabella, Manuel et al.
DOI: 10.1002/ana.22511

Natural killer cell phenotype and clinical response to interferon-beta therapy in multiple sclerosis.

PMID: 21992960
Journal: CLINICAL IMMUNOLOGY
Year: 2011
Reference: Clin Immunol. 2011 Dec;141(3):348-56. Epub 2011 Sep 21.
Impact factor: 3.932
Publication type: Paper in international publication
Authors: , , , , , , et al.
DOI: 10.1016/j.clim.2011.09.006

Search for Specific Biomarkers of IFNbeta Bioactivity in Patients with Multiple Sclerosis.

PMID: 21886806
Journal: PLoS One
Year: 2011
Reference: PLoS One. 2011;6(8):e23634. Epub 2011 Aug 23.
Impact factor: 4.411
Publication type: Paper in international publication
Authors: Malhotra, Sunny, Bustamante, Marta F, Perez-Miralles, Francisco, Rio, Jordi, Ruiz de Villa, Mari Carmen, Vegas, Esteban, Nonell, Lara, Deisenhammer, Florian, Fissolo, Nicolas, Nurtdinov, Ramil N et al.
DOI: 10.1371/journal.pone.0023634

Brainstem lesions in clinically isolated syndromes.

PMID: 21098409
Journal: NEUROLOGY
Year: 2010
Reference: Neurology. 2010 Nov 23;75(21):1933-8.
Impact factor: 8.172
Publication type: Paper in international publication
Authors: Tintore, M, Rovira, A, Arrambide, G, Mitjana, R, Rio, J, Auger, C, Nos, C, Edo, M C, Castillo, J, Horga, A et al.
DOI: 10.1212/WNL.0b013e3181feb26f

Natalizumab plus interferon beta-1a reduces lesion formation in relapsing multiple sclerosis.

PMID: 20236661
Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES
Year: 2010
Reference: J Neurol Sci. 2010 May 15;292(1-2):28-35. Epub 2010 Mar 16.
Impact factor: 2.324
Publication type: Paper in international publication
Authors: Strasser-Fuchs, S, Radue, Ernst-Wilhelm, Stuart, William H, Calabresi, Peter A, Confavreux, Christian, Galetta, Steven L, Rudick, Richard A, Lublin, Fred D, Weinstock-Guttman, Bianca, Wynn, Daniel R et al.
DOI: 10.1016/j.jns.2010.02.012

[Demyelinating lesions as incidental findings in magnetic resonance imaging: a study of 11 cases with clinico-radiological follow-up and a review of the literature]

PMID: 20645263
Journal: REVISTA DE NEUROLOGIA
Year: 2010
Reference: Rev Neurol. 2010 Aug;51(3):129-34.
Impact factor: 1.234
Publication type: Paper in national publication
Authors: Sierra-Marcos, Alba, Mitjana, Raquel, Castillo, Joaquin, Edo, Mari Carmen, Horga-Hernandez, Alejandro, Tintore, Mar, Rio-Izquierdo, Jordi, Auger-Acosta, Cristina, Rovira, Alex, Montalban, Xavier et al.
DOI:

Clinical features of CIS of the brainstem/cerebellum of the kind seen in MS.

PMID: 19946780
Journal: JOURNAL OF NEUROLOGY
Year: 2010
Reference: J Neurol. 2010 May;257(5):742-6. Epub 2009 Nov 28.
Impact factor: 2.903
Publication type: Paper in international publication
Authors: Sastre-Garriga, Jaume, Tintore, M, Nos, C, Tur, C, Rio, J, Tellez, N, Castillo, J, Horga, A, Perkal, H, Comabella, M et al.
DOI: 10.1007/s00415-009-5403-0

Plasma levels of 15d-PGJ are not altered in multiple sclerosis.

PMID: 19538219
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2009
Reference: Eur J Neurol. 2009 Nov;16(11):1197-201.
Impact factor: 2.732
Publication type: Paper in international publication
Authors: Comabella, M, Pradillo, J M, Fernandez, M, Rio, J, Lizasoain, I, Julia, E, Moro, M A, Sastre-Garriga, J, Montalban, X et al.
DOI: 10.1111/j.1468-1331.2009.02696.x

HLA class I and II alleles and response to treatment with interferon-beta in relapsing-remitting multiple sclerosis.

PMID: 19349081
Journal: JOURNAL OF NEUROIMMUNOLOGY
Year: 2009
Reference: J Neuroimmunol. 2009 May 29;210(1-2):116-9.
Impact factor: 3.159
Publication type: Paper in international publication
Authors: Comabella, M, Fernandez-Arquero, M, Rio, J, Guinea, A, Fernandez, M, Cenit, M C, de la Concha, E G, Montalban, X et al.
DOI: 10.1016/j.jneuroim.2009.01.012

Changes in matrix metalloproteinases and their inhibitors during interferon-beta treatment in multiple sclerosis.

PMID: 18945642
Journal: CLINICAL IMMUNOLOGY
Year: 2009
Reference: Clin Immunol. 2009 Feb;130(2):145-50.
Impact factor: 3.606
Publication type: Paper in international publication
Authors: Montalban, Xavier, Oksenberg, Jorge R, Julia, Eva, Comabella, Manuel, Rio, Jordi, Espejo, Carmen, Ruiz de Villa, Mamen, Al-Zayat, Hammad, Nos, Carlos, Deisenhammer, Florian et al.
DOI: 10.1016/j.clim.2008.09.010

Plasma chitotriosidase activity in multiple sclerosis.

PMID: 19176289
Journal: CLINICAL IMMUNOLOGY
Year: 2009
Reference: Clin Immunol. 2009 May;131(2):216-22.
Impact factor: 3.606
Publication type: Paper in international publication
Authors: Vilches, A, Vilarrasa, N, Espejo, C, Montalban, X, Martin-Gallan, P, Rio, J, Dominguez, C, Comabella, M et al.
DOI: 10.1016/j.clim.2008.12.004

[Epileptic status due to non-ketotic hyperglycemia].

PMID: 15766515
Journal: MEDICINA CLINICA
Year: 2005
Reference: Med Clin (Barc). 2005 Mar 19;124(10):398-9. doi: 10.1157/13072580.
Impact factor: 1.005
Publication type: Letter or abstract
Authors: Rovira, Alex, Rio, Jordi, Purroy, Francesc, Toledo, Manuel et al.
DOI: 10.1157/13072580

Thesis

Immunosenescence in multiple sclerosis: innate immunity as a possible therapeutic target

PhD student: Maria Arantza Dema Etxezarreta
Director/s: Herena Eixarch Ahufinger, Carmen Espejo Ruiz
University: Universitat Autònoma de Barcelona
Year: 2023

Clinical monitoring of multiple sclerosis patients using digital technology

PhD student: Luciana Midaglia Fernandez
Director/s: Xavier Montalban Gairín, Jaume Sastre Garriga
University:
Year: 2023

Esclerosis Múltiple y COVID-19: Factores de riesgo e inmunidad humoral y celular

PhD student: Ana Zabalza de Torres, Ana Zabalza de Torres
Director/s: Mar Tintore Subirana, Georgina Arrambide García
University: Universidad Autònoma de Barcelona
Year: 2022

Los astrocitos como diana en la prevención de la neurodegeneración en pacientes con esclerosis múltiple

PhD student: Clara Matute Blanch
Director/s: Manuel Comabella Lopez, Xavier Montalban Gairín
University:
Year: 2021

Inmunomodulación de la vía Th17 como estrategia terapéutica para la esclerosis múltiple

PhD student: Julia Enric Rubio Roca
Director/s: Miguel Chillon Rodriguez, Xavier Montalban Gairín
University:
Year: 2020

The gut microbiota as a therapeutic target in multiple sclerosis

PhD student: Laura Calvo Barreiro
Director/s: Carmen Espejo Ruiz, Herena Eixarch Ahufinger, Xavier Montalban Gairín
University: Universidad Autònoma de Barcelona
Year: 2020

Búsqueda de variantes genéticas causales y estudio de sus implicaciones funcionales en pacientes con esclerosis múltiple

PhD student: Elia Gil Varea
Director/s: Manuel Comabella Lopez, Xavier Montalban Gairín, Sunny Malhotra Sareen
University: Universidad Autònoma de Barcelona
Year: 2018

Factores pronósticos no radiológicos de conversión a esclerosis múltiple y discapacidad de los síndromes clínicamente aislados.

PhD student: Raúl Pelayo Vergara
Director/s: Xavier Montalban Gairín
University:
Year: 2016

Estudio de pseudoatrofia cerebral en los pacientes con esclerosis múltiple

PhD student: Angela Vidal Jordana
Director/s: Xavier Montalban Gairín, Jaume Sastre Garriga
University: Universidad Autònoma de Barcelona
Year: 2016

Indicadores precoces de respuesta al tratamiento con interferón en pacientes con esclerosis múltiple

PhD student: Joaquin Castillo Justribo
Director/s: Xavier Montalban Gairín, Jordi Rio Izquierdo
University: Universidad Autònoma de Barcelona
Year: 2016

Brain Volume and Brain Metabolite Changes in the First Stages of Primary Progressive Multiple Sclerosis - A short-term longitudinal study

PhD student: Jaume Sastre Garriga
Director/s: Xavier Montalban Gairín
University: Universidad Autònoma de Barcelona
Year: 2015

Búsqueda de biomarcadores asociados con la respuesta al interferón-beta en pacientes con esclerosis múltiple.

PhD student: Sunny Malhotra Sareen
Director/s: Manuel Comabella Lopez, Xavier Montalban Gairín
University:
Year: 2014

Estudio clínico y de resonancia magnética del rendimiento cognitivo en síndromes neurológicos aislados sugestivos de esclerosis múltiple

PhD student: M Jesus Arevalo Navines
Director/s: Xavier Montalban Gairín
University: Universidad Autònoma de Barcelona
Year: 2014

Búsqueda de Biomarcadores Asociados con la Respuesta al Tratamiento con Interferón-beta en Pacientes con Esclerosis Múltiple Remitente-Recurrente.

PhD student: Manuel Comabella Lopez
Director/s: Xavier Montalban Gairín
University: Universidad Autònoma de Barcelona
Year: 2013

Estudio clínico y de resonancia magnética orientado al conocimiento del sustrato patológico de la discapacidad en la esclerosis múltiple primariamente progresiva

PhD student: Carmen Tur Gomez, Carmen Tur Gomez
Director/s: Xavier Montalban Gairín, Vicenç Fonollosa Pla
University: Universidad Autònoma de Barcelona
Year: 2012

Funció de les metalotioneínes en la patogenia de l’encefalomielitis autoimmune experimental i de l’esclerosi múltiple. Implicacions terapèutiques

PhD student: Carmen Espejo Ruiz
Director/s:
University: Universidad Autònoma de Barcelona
Year: 2005

Blog

News

In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.

Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.

The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.

Job offers

PostdoctoralSenior Researcher-Clinical Neuroimmunology
Start date:
28/09/2023
End date:
12/10/2023
Document: Download
Clinical Trial Study Coordinator - Multiple Sclerosis Centre of Catalonia-VHIR
Start date:
11/07/2023
End date:
31/08/2023
Document: Download
Postdoctoral Researcher - Clinical Neuroimmunology.
Start date:
22/06/2023
End date:
12/07/2023
Document: Download

Rates

Simoa HD1 equipment

We are seeking healthy volunteers for a study to find biomarkers of multiple sclerosis

We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.

More information