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Clinical Neuroimmunology

The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches. 

Team

Sunny Malhotra Sareen

Sunny Malhotra Sareen

Main researcher
Clinical Neuroimmunology
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Carmen Espejo Ruiz

Carmen Espejo Ruiz

Main researcher
Clinical Neuroimmunology
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Elisenda Anglada Clofent

Elisenda Anglada Clofent

Predoctoral researcher
Clinical Neuroimmunology
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Javier Villacieros Álvarez

Javier Villacieros Álvarez

Predoctoral researcher
Clinical Neuroimmunology
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Julia Enric Rubio Roca

Julia Enric Rubio Roca

Administration and Management
Clinical Neuroimmunology
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Sergio Vergara Ruiz

Sergio Vergara Ruiz

Administration and Management
Clinical Neuroimmunology
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Sunny Malhotra Sareen

Sunny Malhotra Sareen

Main researcher
Clinical Neuroimmunology
Read more
Carmen Espejo Ruiz

Carmen Espejo Ruiz

Main researcher
Clinical Neuroimmunology
Read more
Elisenda Anglada Clofent

Elisenda Anglada Clofent

Predoctoral researcher
Clinical Neuroimmunology
Read more
Javier Villacieros Álvarez

Javier Villacieros Álvarez

Predoctoral researcher
Clinical Neuroimmunology
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Julia Enric Rubio Roca

Julia Enric Rubio Roca

Administration and Management
Clinical Neuroimmunology
Read more
Sergio Vergara Ruiz

Sergio Vergara Ruiz

Administration and Management
Clinical Neuroimmunology
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Projects

Medició del nivell d'activitat física i anàlisi dels factors associats a l'adherència en persones amb esclerosi múltiple

IP: Carme Santoyo Medina
Collaborators: Jaume Sastre Garriga, Ingrid Galán Cartaña, Montserrat Janer Cabo, M Jesus Arevalo Navines, Edwin Roger Meza Murillo, Xavier Montalban Gairín, Helena Llorente Blasco
Funding agency: Societat Catalano_Balear de Fisioteràpia
Funding: 3000
Reference: SCBF/2023/SANTOYO
Duration: 18/12/2023 - 17/12/2026

TACTIC: Explorando soluciones a los retos de salud mediante ciencia disruptiva, terapias avanzadas y medicina de sistemas

IP: Begoña Benito Villabriga
Collaborators: Carmen Escudero Iriarte, Laia Ventura i Expósito, Susana Otero Romero, Ibane Abasolo Olaortua, Ignacio Ferreira González, José Antonio Barrabés Riu, Carlos Nos Llopis, Pablo Velasco Puyó, Jose Fernando Rodríguez Palomares, María Rosario Pérez- Torres Lobato, Sunny Malhotra Sareen, Belen Perez Dueñas, Jaume Sastre Garriga, Joan López Hellin, Antonia Sambola Ayala, Jordi Rio Izquierdo, Nuria Rivas Gandara, Jordi Perez Rodon, Aroa Soriano Fernández, Manuel Comabella Lopez, Antonio Rodríguez Sinovas, Gisela Teixido Tura, Antonia Pijuan Domenech, Roser Ferrer Costa, Joaquin Seras Franzoso, Carmen Tur Gomez, Maria Cristina Díaz de Heredia Rubio, Laia Yañez Bisbe, Julia German Cortes, Maria Jose Pérez García, Miguel Segura Ginard, Diego Baranda Martínez-Abasca, Cristina Auger Acosta, Neus Bellera Gotarda, Herena Eixarch Ahufinger, M Mar Mañu Pereira, Deborah Pareto Onghena, Lorena Valero Arrese, Aitor Uribarri Gonzalez, Jordi Bañeras Rius, Alex Rovira Cañellas, Mar Tintore Subirana, Bruno García del Blanco, Maria Teresa Salcedo Allende, Marisol Ruiz Meana, Ana Belén Méndez Fernández, Xavier Montalban Gairín, Simon Schwartz Navarro, Anna Llort Sales, Carmen Espejo Ruiz, Raquel Hladun Alvaro, Angels Alcina Mila, Sandra Mancilla Zamora, Zamira Vanessa Diaz Riascos, Ana Zabalza de Torres, Marc Miquel Moltó Abad, Javier Inserte Igual, Luciana Midaglia Fernandez, Elizabeth Pando Rau, Gabriela Guillén Burrieza, Ana Laura Cazurro Gutierrez, David Gómez Andrés, Alvaro Cobo Calvo, Alvaro Calabuig Goena, Joaquin Castillo Justribo, Lydia Dux-Santoy Hurtado, Lucas Moreno Martín-Retortillo, Andres Miguez Gonzalez, Josep Roma Castanyer, Laura Dos Subirá, Nicolás Miguel Fissolo, Maria Nazarena Pizzi, Tian Tian, Fernanda Raquel Da Silva Andrade, Diana Fernandes de Rafael, Andrea Guala
Funding agency: Instituto de Salud Carlos III
Funding: 2494527.53
Reference: FORT23/00034
Duration: 01/01/2024 - 31/12/2027

Caracterización de las infecciones y de su impacto en pacientes con Esclerosis Múltiple en la era de los tratamientos inmunosupresores de alta eficacia

IP: Susana Otero Romero
Collaborators: Imane Boutitah Benyaich, Blanca Borras Bermejo, Anna Falcó Roget, Mar Tintore Subirana, Ana Zabalza de Torres, Jesus Trejo Zahinos, Enrique Rodríguez Zafra
Funding agency: Instituto de Salud Carlos III
Funding: 115000
Reference: PI23/01654
Duration: 01/01/2024 - 31/12/2026

Investigation of pathology-informed neuroimaging predictors of progression independent of relapse activity at the first attack of multiple sclerosis: from histopathology to routinely acquired anatomical MRI, through advanced quantitative neuroimaging and

IP: Carmen Tur Gomez
Collaborators: Carlos Domínguez Pérez, Miriam Izquierdo Sans
Funding agency: Instituto de Salud Carlos III
Funding: 242500
Reference: CP23/00117
Duration: 01/01/2024 - 31/12/2028

Publications

Forever young.

PMID: 39784932
Journal: Multiple Sclerosis Journal
Year: 2025
Reference: Mult Scler. 2025 Jan;31(1):3-5. doi: 10.1177/13524585241311154.
Impact factor:
Publication type: Editorail in international publication
Authors: Brownlee, Wallace; Chard, Declan T; Graves, Jennifer; Hedstrom, Anna Karin; Kim, Ho Jin; Moccia, Marcello; Ontaneda, Daniel; Rocca, Maria A; Sastre-Garriga, Jaume; Thompson, Alan J et al.
DOI: 10.1177/13524585241311154

Explaining cognitive function in multiple sclerosis through networks of grey and white matter features: a joint independent component analysis.

PMID: 39812878
Journal: JOURNAL OF NEUROLOGY
Year: 2025
Reference: J Neurol. 2025 Jan 15;272(2):142. doi: 10.1007/s00415-024-12795-2.
Impact factor:
Publication type: Paper in international publication
Authors: Calhoun, Vince D; Chard, Declan T; Eierud, Cyrus; Eshaghi, Arman; Jolly, Amy; Kanber, Baris; Lageman, Senne B; Prados, Ferran; Sahi, Nitin; Schoonheim, Menno M et al.
DOI: 10.1007/s00415-024-12795-2

Brain tissue integrity in neuromyelitis optica spectrum disorder through T1-w/T2-w ratio, MTR and DTI.

PMID: 39821642
Journal: JOURNAL OF NEUROLOGY
Year: 2025
Reference: J Neurol. 2025 Jan 17;272(2):157. doi: 10.1007/s00415-024-12869-1.
Impact factor:
Publication type: Paper in international publication
Authors: Avolio, Isabella; Boaventura, Mateus; Callegaro, Dagoberto; da Costa Leite, Claudia; de Medeiros Rimkus, Carolina; Fragoso, Diego Cardoso; Pareto, Deborah; Pereira, Samira Apostolos; Rovira, Alex; Sastre-Garriga, Jaume et al.
DOI: 10.1007/s00415-024-12869-1

Autologous haematopoietic stem cell transplantation for treatment of multiple sclerosis and neuromyelitis optica spectrum disorder - recommendations from ECTRIMS and the EBMT.

PMID: 39814869
Journal: Nature Reviews Neurology
Year: 2025
Reference: Nat Rev Neurol. 2025 Jan 15. doi: 10.1038/s41582-024-01050-x.
Impact factor:
Publication type: Paper in international publication
Authors: Alexander, Tobias; Amato, Maria Pia; Bo, Lars; Boffa, Giacomo; Burman, Joachim; Ciccarelli, Olga; Cohen, Jeffrey A; Derfuss, Tobias; Farge, Dominique; Freedman, Mark S et al.
DOI: 10.1038/s41582-024-01050-x

What contributes to disability in progressive MS? A brain and cervical cord-matched quantitative MRI study.

PMID: 38372019
Journal: Multiple Sclerosis Journal
Year: 2024
Reference: Mult Scler. 2024 Feb 19:13524585241229969. doi: 10.1177/13524585241229969.
Impact factor:
Publication type: Paper in international publication
Authors: Battiston, Marco; Calvi, Alberto; Ciccarelli, Olga; Collorone, Sara; Grussu, Francesco; Kanber, Baris; Martinelli, Daniele; Pajak, Patrizia; Prados, Ferran; Ricciardi, Antonio et al.
DOI: 10.1177/13524585241229969

T1/T2-weighted ratio: A feasible MRI biomarker in multiple sclerosis.

PMID: 38389172
Journal: Multiple Sclerosis Journal
Year: 2024
Reference: Mult Scler. 2024 Feb 22:13524585241233448. doi: 10.1177/13524585241233448.
Impact factor:
Publication type: Paper in international publication
Authors: Boaventura, Mateus; Pareto, Deborah; Rimkus, Carolina de Medeiros; Rovira, Alex; Sastre-Garriga, Jaume et al.
DOI: 10.1177/13524585241233448

Cross-cultural validity and reliability of the comprehensive assessment of acceptance and commitment therapy processes (CompACT) in people with multiple sclerosis.

PMID: 38401014
Journal: QUALITY OF LIFE RESEARCH
Year: 2024
Reference: Qual Life Res. 2024 Feb 24. doi: 10.1007/s11136-024-03609-z.
Impact factor:
Publication type: Paper in international publication
Authors: Anglada, Elisenda; Confalonieri, Paolo; Galan, Ingrid; Giordano, Andrea; Giovannetti, Ambra Mara; Hoyer, Jurgen; Menendez, Rebeca; Pakenham, Kenneth Ian; Pottgen, Jana; Rosato, Rosalba et al.
DOI: 10.1007/s11136-024-03609-z

Efficacy and safety results after >3.5 years of treatment with the Bruton's tyrosine kinase inhibitor evobrutinib in relapsing multiple sclerosis: Long-term follow-up of a Phase II randomised clinical trial with a cerebrospinal fluid sub-study.

PMID: 38436271
Journal: Multiple Sclerosis Journal
Year: 2024
Reference: Mult Scler. 2024 Mar 4:13524585241234783. doi: 10.1177/13524585241234783.
Impact factor:
Publication type: Paper in international publication
Authors: Arnold, Douglas L; Benkert, Pascal; Dyroff, Martin; Guehring, Hans; Harlow, Danielle E; Hyvert, Yann; Kuhle, Jens; Montalban, Xavier; Piasecka-Stryczynska, Karolina; Seitzinger, Andrea et al.
DOI: 10.1177/13524585241234783

Serum Levels of CXCL13 Are Associated With Teriflunomide Response in Patients With Multiple Sclerosis.

PMID: 36411079
Journal: Neurology-Neuroimmunology & Neuroinflammation
Year: 2023
Reference: Neurol Neuroimmunol Neuroinflamm. 2022 Nov 21;10(1):e200050. doi: 10.1212/NXI.0000000000200050. Print 2023 Jan.
Impact factor:
Publication type: Paper in international publication
Authors: Comabella, Manuel; Fissolo, Nicolas; Gutierrez, Lucia; Montalban, Xavier; Pappolla, Agustin; Perez-Hoyos, Santiago; Rio, Jordi; Sanchez, Alex; Villar, Luisa M et al.
DOI: 10.1212/NXI.0000000000200050

Specific Patterns of Immune Cell Dynamics May Explain the Early Onset and Prolonged Efficacy of Cladribine Tablets: A MAGNIFY-MS Substudy.

PMID: 36411081
Journal: Neurology-Neuroimmunology & Neuroinflammation
Year: 2023
Reference: Neurol Neuroimmunol Neuroinflamm. 2022 Nov 21;10(1):e200048. doi: 10.1212/NXI.0000000000200048. Print 2023 Jan.
Impact factor:
Publication type: Paper in international publication
Authors: Achiron, Anat; Barkhof, Frederik; Boschert, Ursula; Chan, Andrew; Chudecka, Anita; De Stefano, Nicola; Derfuss, Tobias; Hodgkinson, Suzanne; Holmberg, Kristina H; Leocani, Letizia et al.
DOI: 10.1212/NXI.0000000000200048

Preliminary validity of the Draw a Shape Test for upper extremity assessment in multiple sclerosis.

PMID: 36563127
Journal: Annals of Clinical and Translational Neurology
Year: 2023
Reference: Ann Clin Transl Neurol. 2023 Feb;10(2):166-180. doi: 10.1002/acn3.51705. Epub 2022 Dec 23.
Impact factor:
Publication type: Paper in international publication
Authors: Baker, Michael; Belachew, Shibeshih; Bernasconi, Corrado; Dondelinger, Frank; Ganzetti, Marco; Gossens, Christian; Graves, Jennifer S; Lindemann, Michael; Lipsmeier, Florian; Montalban, Xavier et al.
DOI: 10.1002/acn3.51705

Association of Early Progression Independent of Relapse Activity With Long-term Disability After a First Demyelinating Event in Multiple Sclerosis.

PMID: 36534392
Journal: JAMA Neurology
Year: 2023
Reference: JAMA Neurol. 2023 Feb 1;80(2):151-160. doi: 10.1001/jamaneurol.2022.4655.
Impact factor:
Publication type: Paper in international publication
Authors: Arrambide, Georgina; Auger, Cristina; Carbonell-Mirabent, Pere; Castillo, Joaquin; Cobo-Calvo, Alvaro; Comabella, Manuel; Galan, Ingrid; Midaglia, Luciana; Montalban, Xavier; Nos, Carlos et al.
DOI: 10.1001/jamaneurol.2022.4655

Consensus statement on the use of alemtuzumab in daily clinical practice in Spain.

PMID: 36195374
Journal: NEUROLOGIA
Year: 2022
Reference: Neurologia (Engl Ed). 2022 Oct;37(8):615-630. doi: 10.1016/j.nrleng.2019.11.001. Epub 2020 Mar 12.
Impact factor:
Publication type: Paper in national publication
Authors: Alvarez Cermeno, J C; Arnal Garcia, C; Arroyo Gonzalez, R; Brieva Ruiz, L; Calles Hernandez, C; Eichau Madueno, S; Fernandez Fernandez, O; Fernandez-Prada, M; Garcia Merino, A; Garcia Vazquez, E et al.
DOI: 10.1016/j.nrleng.2019.11.001

Association of NEDA-4 With No Long-term Disability Progression in Multiple Sclerosis and Comparison With NEDA-3: A Systematic Review and Meta-analysis.

PMID: 36224046
Journal: Neurology-Neuroimmunology & Neuroinflammation
Year: 2022
Reference: Neurol Neuroimmunol Neuroinflamm. 2022 Oct 12;9(6). pii: 9/6/e200032. doi: 10.1212/NXI.0000000000200032. Print 2022 Nov.
Impact factor:
Publication type: Review in international publication
Authors: Dababneh, Dina; Montalban, Xavier; Muccilli, Alexandra; Rotstein, Dalia; Saab, Georges; Shah, Prakesh; Solomon, Jacqueline M; Sormani, Maria Pia; Ye, Xiang Y et al.
DOI: 10.1212/NXI.0000000000200032

Detection of lesions in the optic nerve with magnetic resonance imaging using a 3D convolutional neural network.

PMID: 36126515
Journal: NeuroImage-Clinical
Year: 2022
Reference: Neuroimage Clin. 2022;36:103187. doi: 10.1016/j.nicl.2022.103187. Epub 2022 Sep 13.
Impact factor:
Publication type: Paper in international publication
Authors: Alberich, Manel; Calderon, Willem; Camara, Oscar; Frias, Marcos; Garcia-Vidal, Aran; Marti-Juan, Gerard; Montalban, Xavier; Pareto, Deborah; Piella, Gemma; Rovira, Alex et al.
DOI: 10.1016/j.nicl.2022.103187

Expert-Agreed Practical Recommendations on the Use of Cladribine.

PMID: 36068429
Journal: Neurology and Therapy
Year: 2022
Reference: Neurol Ther. 2022 Dec;11(4):1475-1488. doi: 10.1007/s40120-022-00394-0. Epub 2022 Sep 6.
Impact factor:
Publication type: Paper in international publication
Authors: Ares Luque, Adrian; Garcia Dominguez, Jose M; Hernandez Perez, Miguel A; Landete Pascual, Lamberto; Lopez Ruiz, Rocio; Martin-Martinez, Jesus; Meca-Lallana, Virginia; Prieto Gonzalez, Jose M; Sastre-Garriga, Jaume et al.
DOI: 10.1007/s40120-022-00394-0

The Multiple Sclerosis Data Alliance Catalogue: Enabling Web-Based Discovery of Metadata from Real-World Multiple Sclerosis Data Sources.

PMID: 35035297
Journal: International journal of MS care
Year: 2021
Reference: Int J MS Care. 2021 Nov-Dec;23(6):261-268. doi: 10.7224/1537-2073.2021-006. Epub 2021 Dec 29.
Impact factor:
Publication type: Paper in international publication
Authors: Bergmann, Arnfin; Boziki, Marina; Brola, Waldemar; Carra, Adriana; Cristiano, Edgardo; Dalla Costa, Gloria; de Carvalho Sousa, Nise Alessandra; Delmas, Amber; Dobson, Ruth; Drulovic, Jelena et al.
DOI: 10.7224/1537-2073.2021-006

Immunomodulatory Effects Associated with Cladribine Treatment.

PMID: 34943995
Journal: Cells
Year: 2021
Reference: Cells. 2021 Dec 10;10(12). pii: cells10123488. doi: 10.3390/cells10123488.
Impact factor:
Publication type: Paper in international publication
Authors: Boschert, Ursula; Calvo-Barreiro, Laura; Comabella, Manuel; Eixarch, Herena; Espejo, Carmen; Fissolo, Nicolas; Montalban, Xavier et al.
DOI: 10.3390/cells10123488

Assessing Lumbar Plexus and Sciatic Nerve Damage in Relapsing-Remitting Multiple Sclerosis Using Magnetisation Transfer Ratio.

PMID: 34899579
Journal: Frontiers in Neurology
Year: 2021
Reference: Front Neurol. 2021 Nov 25;12:763143. doi: 10.3389/fneur.2021.763143. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Battiston, Marco; Boonsuth, Ratthaporn; Ciccarelli, Olga; Collorone, Sara; Cortese, Rosa; Gandini Wheeler-Kingshott, Claudia A M; Grussu, Francesco; Prados, Ferran; Samson, Rebecca S; Schneider, Torben et al.
DOI: 10.3389/fneur.2021.763143

Optical coherence tomography in multiple sclerosis: A 3-year prospective multicenter study.

PMID: 34792863
Journal: Annals of Clinical and Translational Neurology
Year: 2021
Reference: Ann Clin Transl Neurol. 2021 Dec;8(12):2235-2251. doi: 10.1002/acn3.51473. Epub 2021 Nov 18.
Impact factor:
Publication type: Paper in international publication
Authors: Agoropoulou, Catherine; Barkhof, Frederik; Calabresi, Peter A; Gerendas, Bianca S; Green, Ari J; Kardon, Randy; Paul, Friedemann; Petzold, Axel; Saidha, Shiv; Sastre-Garriga, Jaume et al.
DOI: 10.1002/acn3.51473

New Algorithms Improving PML Risk Stratification in MS Patients Treated With Natalizumab.

PMID: 33408681
Journal: Frontiers in Neurology
Year: 2020
Reference: Front Neurol. 2020 Dec 17;11:579438. doi: 10.3389/fneur.2020.579438. eCollection 2020.
Impact factor:
Publication type: Paper in international publication
Authors: Aguera-Morales, Eduardo; Aladro, Yolanda; Alvarez, Elena; Alvarez-Cermeno, Jose C; Alvarez-Lafuente, Roberto; Arroyo, Rafael; Belenguer-Benavides, Antonio; Blanco, Yolanda; Bsteh, Gabriel; Calles, Carmen et al.
DOI: 10.3389/fneur.2020.579438

Prognostication and contemporary management of clinically isolated syndrome.

PMID: 33361410
Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Year: 2020
Reference: J Neurol Neurosurg Psychiatry. 2020 Dec 24:jnnp-2020-323087. doi: 10.1136/jnnp-2020-323087.
Impact factor:
Publication type: Review in international publication
Authors: Allen, Christopher Martin; Evangelou, Nikos; Mowry, Ellen; Tintore, Mar et al.
DOI: 10.1136/jnnp-2020-323087

Long-term safety data from the cladribine tablets clinical development program in multiple sclerosis.

PMID: 33296971
Journal: Multiple Sclerosis and Related Disorders
Year: 2020
Reference: Mult Scler Relat Disord. 2020 Nov;46:102572. doi: 10.1016/j.msard.2020.102572. Epub 2020 Oct 8.
Impact factor:
Publication type: Paper in international publication
Authors: Comi, G; Cook, S; Damian, D; Galazka, A; Giovannoni, G; Leist, T; Montalban, X; Nolting, A; Syed, S et al.
DOI: 10.1016/j.msard.2020.102572

Radiologically isolated syndrome: targeting miRNAs as prognostic biomarkers.

PMID: 33290101
Journal: Epigenomics
Year: 2020
Reference: Epigenomics. 2020 Dec;12(23):2065-2076. doi: 10.2217/epi-2020-0172. Epub 2020 Dec 8.
Impact factor:
Publication type: Paper in international publication
Authors: Buxo, Maria; Comabella, Manuel; Gomez, Imma; Martin, Maria Munoz-San; Matute-Blanch, Clara; Perkal, Hector; Quintana, Ester; Ramio-Torrenta, Lluis; Robles-Cedeno, Rene; Torras, Sandra et al.
DOI: 10.2217/epi-2020-0172

SVM recursive feature elimination analyses of structural brain MRI predicts near-term relapses in patients with clinically isolated syndromes suggestive of multiple sclerosis.

PMID: 31734524
Journal: NeuroImage-Clinical
Year: 2019
Reference: Neuroimage Clin. 2019;24:102011. doi: 10.1016/j.nicl.2019.102011. Epub 2019 Oct 22.
Impact factor:
Publication type: Paper in international publication
Authors: Alexander, Daniel C; Barkhof, Frederik; Chard, Declan T; Ciccarelli, Olga; De Stefano, Nicola; Enzinger, Christian; Filippi, Massimo; Frederiksen, Jette L; Gasperini, Claudio; Giorgio, Antonio et al.
DOI: 10.1016/j.nicl.2019.102011

Characteristics of morphologic macular abnormalities in neuroimmunology practice.

PMID: 29125422
Journal: Multiple Sclerosis Journal
Year: 2019
Reference: Mult Scler. 2019 Mar;25(3):361-371. doi: 10.1177/1352458517741206. Epub 2017 Nov 10.
Impact factor:
Publication type: Paper in international publication
Authors: Al-Louzi, Omar; Balcer, Laura J; Beh, Shin C; Button, Julia; Calabresi, Peter A; Frohman, Elliot M; Newsome, Scott D; Saidha, Shiv; Sotirchos, Elias S; Vidal-Jordana, Angela et al.
DOI: 10.1177/1352458517741206

An asymptomatic new lesion on MRI is a relapse and should be treated accordingly - Commentary.

PMID: 31674875
Journal: Multiple Sclerosis Journal
Year: 2019
Reference: Mult Scler. 2019 Dec;25(14):1845-1847. doi: 10.1177/1352458519885110. Epub 2019 Nov 1.
Impact factor:
Publication type: Editorail in international publication
Authors: Arrambide, Georgina; Tintore, Mar et al.
DOI: 10.1177/1352458519885110

Clinically relevant cranio-caudal patterns of cervical cord atrophy evolution in MS.

PMID: 31611336
Journal: NEUROLOGY
Year: 2019
Reference: Neurology. 2019 Nov 12;93(20):e1852-e1866. doi: 10.1212/WNL.0000000000008466. Epub 2019 Oct 14.
Impact factor:
Publication type: Paper in international publication
Authors: Barkhof, Frederik; Bellenberg, Barbara; Bisecco, Alvino; Ciccarelli, Olga; Comi, Giancarlo; Eisele, Philipp; Filippi, Massimo; Gallo, Antonio; Gass, Achim; Gobbi, Claudio et al.
DOI: 10.1212/WNL.0000000000008466

Trial of Fingolimod versus Interferon Beta-1a in Pediatric Multiple Sclerosis.

PMID: 30207920
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2018
Reference: N Engl J Med. 2018 Sep 13;379(11):1017-1027. doi: 10.1056/NEJMoa1800149.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarenga, Regina; Anlar, Banu; Arnold, Douglas L; Ayala, Ricardo; Bajer-Kornek, Barbara; Banwell, Brenda; Bar-Or, Amit; Bhise, Vikram; Blaschek, Astrid; Bojinova-Tchamova, Veneta et al.
DOI: 10.1056/NEJMoa1800149

Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk.

PMID: 30343897
Journal: CELL
Year: 2018
Reference: Cell. 2018 Nov 29;175(6):1679-1687.e7. doi: 10.1016/j.cell.2018.09.049. Epub 2018 Oct 18.
Impact factor:
Publication type: Paper in international publication
Authors: Agliardi, Cristina; Alfredsson, Lars; Andlauer, Till F M; Ban, Maria; Baranzini, Sergio E; Barcellos, Lisa F; Barizzone, Nadia; Bayas, Antonios; Beecham, Ashley H; Bergh, Florian Then et al.
DOI: 10.1016/j.cell.2018.09.049

Effect of natalizumab on disease progression in secondary progressive multiple sclerosis (ASCEND): a phase 3, randomised, double-blind, placebo-controlled trial with an open-label extension.

PMID: 29545067
Journal: LANCET NEUROLOGY
Year: 2018
Reference: Lancet Neurol. 2018 May;17(5):405-415. doi: 10.1016/S1474-4422(18)30069-3. Epub 2018 Mar 12.
Impact factor:
Publication type: Paper in international publication
Authors: Achiron, Anat; Airas, Laura; Al Khedr, Abdullatif; Alvarez Cermeno, Jose Carlos; Arnold, Douglas L; Ayuso, Guillermo Izquierdo; Bandari, Daniel; Bartholome, Emmanuel; Baum, Karl; Bergamaschi, Roberto et al.
DOI: 10.1016/S1474-4422(18)30069-3

Risk knowledge of people with relapsing-remitting multiple sclerosis - Results of an international survey.

PMID: 30496233
Journal: PLoS One
Year: 2018
Reference: PLoS One. 2018 Nov 29;13(11):e0208004. doi: 10.1371/journal.pone.0208004. eCollection 2018.
Impact factor:
Publication type: Paper in international publication
Authors: Beckmann, Yesim; Drulovic, Jelena; Galea, Ian; Giordano, Andrea; Heerings, Marco; Heesen, Christoph; Jongen, Peter Joseph; Kopke, Sascha; Liethmann, Katrin; Poettgen, Jana et al.
DOI: 10.1371/journal.pone.0208004

Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis.

PMID: 28002688
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2017
Reference: N Engl J Med. 2017 Jan 19;376(3):209-220. doi: 10.1056/NEJMoa1606468. Epub 2016 Dec 21.
Impact factor:
Publication type: Paper in international publication
Authors: Arnold, Douglas L; Bar-Or, Amit; Belachew, Shibeshih; Chin, Peter; Comi, Giancarlo; de Seze, Jerome; Fontoura, Paulo; Garren, Hideki; Giovannoni, Gavin; Hartung, Hans-Peter et al.
DOI: 10.1056/NEJMoa1606468

Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis.

PMID: 28002679
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2017
Reference: N Engl J Med. 2017 Jan 19;376(3):221-234. doi: 10.1056/NEJMoa1601277. Epub 2016 Dec 21.
Impact factor:
Publication type: Paper in international publication
Authors: Arnold, Douglas L; Bar-Or, Amit; Belachew, Shibeshih; Chin, Peter; Comi, Giancarlo; Fontoura, Paulo; Garren, Hideki; Giovannoni, Gavin; Hartung, Hans-Peter; Hauser, Stephen L et al.
DOI: 10.1056/NEJMoa1601277

Semaphorin 7A as a Potential Therapeutic Target for Multiple Sclerosis.

PMID: 27714632
Journal: MOLECULAR NEUROBIOLOGY
Year: 2017
Reference: Mol Neurobiol. 2017 Aug;54(6):4820-4831. doi: 10.1007/s12035-016-0154-2. Epub 2016 Oct 6.
Impact factor:
Publication type: Paper in international publication
Authors: Calvo-Barreiro, Laura; Castillo, Mireia; Costa, Carme; Del Rio, Jose A; Eixarch, Herena; Espejo, Carmen; Gil, Vanessa; Gutierrez-Franco, Ana; Montalban, Xavier et al.
DOI: 10.1007/s12035-016-0154-2

Decreased soluble IFN-beta receptor (sIFNAR2) in multiple sclerosis patients: A potential serum diagnostic biomarker.

PMID: 27613121
Journal: Multiple Sclerosis Journal
Year: 2017
Reference: Mult Scler. 2017 Jun;23(7):937-945. doi: 10.1177/1352458516667564. Epub 2016 Sep 9.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Cermeno, Jose C; Comabella, Manuel; Fernandez, Oscar; Hurtado-Guerrero, Isaac; Leyva, Laura; Montalban, Xavier; Oliver-Martos, Begona; Orpez-Zafra, Teresa; Pavia, Jose; Pinto-Medel, Maria J et al.
DOI: 10.1177/1352458516667564

Differential expression of sema3A and sema7A in a murine model of multiple sclerosis: Implications for a therapeutic design.

PMID: 26686462
Journal: CLINICAL IMMUNOLOGY
Year: 2016
Reference: Clin Immunol. 2016 Feb;163:22-33. doi: 10.1016/j.clim.2015.12.005. Epub 2015 Dec 10.
Impact factor:
Publication type: Paper in international publication
Authors: Bribian, Ana; Castillo, Mireia; Costa, Carme; de Castro, Fernando; Eixarch, Herena; Espejo, Carmen; Gutierrez-Franco, Ana; Medina-Rodriguez, Eva M; Montalban, Xavier et al.
DOI: 10.1016/j.clim.2015.12.005

Protein-based classifier to predict conversion from clinically isolated syndrome to multiple sclerosis.

PMID: 26552840
Journal: MOLECULAR & CELLULAR PROTEOMICS
Year: 2016
Reference: Mol Cell Proteomics. 2016 Jan;15(1):318-28. doi: 10.1074/mcp.M115.053256. Epub 2015 Nov 9.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Cermeno, Jose Carlos; Borras, Eva; Canto, Ester; Chiva, Cristina; Choi, Meena; Comabella, Manuel; Montalban, Xavier; Sabido, Eduard; Villar, Luisa Maria; Vitek, Olga et al.
DOI: 10.1074/mcp.M115.053256

PML risk stratification using anti-JCV antibody index and L-selectin.

PMID: 26432858
Journal: Multiple Sclerosis Journal
Year: 2016
Reference: Mult Scler. 2016 Jul;22(8):1048-60. doi: 10.1177/1352458515607651. Epub 2015 Oct 2.
Impact factor:
Publication type: Paper in international publication
Authors: Bertolotto, Antonio; Brassat, David; Breuer, Johanna; Canto, Ester; Comabella, Manuel; Du Pasquier, Renaud A; Gold, Ralf; Gorlich, Dennis; Hohlfeld, Reinhard; Jacobi, Annett et al.
DOI: 10.1177/1352458515607651

A 10-year follow-up of the European multicenter trial of interferon beta-1b in secondary-progressive multiple sclerosis.

PMID: 26362898
Journal: Multiple Sclerosis Journal
Year: 2016
Reference: Mult Scler. 2016 Apr;22(4):533-43. doi: 10.1177/1352458515594440. Epub 2015 Sep 11.
Impact factor:
Publication type: Paper in international publication
Authors: Amato, M P; Baum, K; Bayas, A; Brassat, D; Brochet, B; Buttmann, M; Confavreux, C; D'Hooghe, M; De Keyser, J; Disanto, G et al.
DOI: 10.1177/1352458515594440

Ischemic postconditioning of the isolated human myocardium: Role of the applied protocol.

PMID: 28785680
Journal: International journal of cardiology. Heart & vascu
Year: 2015
Reference: Int J Cardiol Heart Vasc. 2015 May 23;8:55-61. doi: 10.1016/j.ijcha.2015.05.009. eCollection 2015 Sep 1.
Impact factor:
Publication type: Paper in international publication
Authors: Blasco-Lucas, Arnau; Casos, Kelly; Ferrer-Curriu, Gemma; Galinanes, Manuel; Gracia-Baena, Juan Manuel; Igual, Alberto; Perez, Maria-Llanos; Permanyer, Eduard; Sureda, Carlos et al.
DOI: 10.1016/j.ijcha.2015.05.009

Advances in the management of multiple sclerosis symptoms: pathophysiology and assessment of spasticity in multiple sclerosis.

PMID: 26611266
Journal: Neurodegenerative disease management
Year: 2015
Reference: Neurodegener Dis Manag. 2015;5(6 Suppl):15-7. doi: 10.2217/nmt.15.56.
Impact factor:
Publication type: Paper in international publication
Authors: Tintore, Mar et al.
DOI: 10.2217/nmt.15.56

A new cognitive rehabilitation programme for patients with multiple sclerosis: the 'MS-line! Project'

PMID: 25480865
Journal: MULT SCLER J
Year: 2015
Reference: Mult Scler. 2015 Sep;21(10):1344-8. doi: 10.1177/1352458514561905. Epub 2014 Dec 5.
Impact factor:
Publication type: Paper in international publication
Authors: Freixenet, Jordi; Garcia, Rafael; Genis, David; Gich, Jordi; Montalban, Xavier; Ramio-Torrenta, Lluis; Silva, Yolanda; Vilanova, Joan Carles et al.
DOI: 10.1177/1352458514561905

Lack of efficacy of mitoxantrone in primary progressive Multiple Sclerosis irrespective of pharmacogenetic factors: A multi-center, retrospective analysis.

PMID: 25468777
Journal: J NEUROIMMUNOL
Year: 2015
Reference: J Neuroimmunol. 2015 Jan 15;278:277-9. doi: 10.1016/j.jneuroim.2014.11.017. Epub 2014 Nov 20.
Impact factor:
Publication type: Paper in international publication
Authors: Chan, Andrew; Comabella, Manuel; Fleischer, Vinzenz; Gold, Ralf; Grey Nee Cotte, Steffi; Kruse, Niels; Montalban, Xavier; Salmen Nee Stroet, Anke; Starck, Michaela; von Ahsen, Nico et al.
DOI: 10.1016/j.jneuroim.2014.11.017

Five-year results from a phase 2 study of oral fingolimod in relapsing multiple sclerosis.

PMID: 24293455
Journal: Multiple Sclerosis Journal
Year: 2014
Reference: Mult Scler. 2014 Jun;20(7):877-81. doi: 10.1177/1352458513513059. Epub 2013 Nov 30.
Impact factor:
Publication type: Paper in international publication
Authors: Cremer, M; de Vera, A; Francis, G; Izquierdo, G; Kappos, L; Montalban, X; O'Connor, P; Radue, Ew; Sfikas, N; von Rosenstiel, P et al.
DOI: 10.1177/1352458513513059

No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis.

PMID: 24234648
Journal: HUMAN MOLECULAR GENETICS
Year: 2014
Reference: Hum Mol Genet. 2014 Apr 1;23(7):1916-22. doi: 10.1093/hmg/ddt574. Epub 2013 Nov 13.
Impact factor:
Publication type: Paper in international publication
Authors: Al-Chalabi, Ammar; Andersen, Peter M; Bahlo, Melanie; Barcellos, Lisa; Booth, David; Booth, David R; Broadley, Simon; Brown, Matthew A; Brown, Robert H Jr; Butzkueven, Helmut et al.
DOI: 10.1093/hmg/ddt574

A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility.

PMID: 24430173
Journal: GENES AND IMMUNITY
Year: 2014
Reference: Genes Immun. 2014 Mar;15(2):126-32. doi: 10.1038/gene.2013.70. Epub 2014 Jan 16.
Impact factor:
Publication type: Paper in international publication
Authors: Ban, Maria; Band, Gavin; Baranzini, S E; Baranzini, Sergio; Barcellos, Lisa; Barroso, Ines; Barroso, Ines; Beecham, Ashley; Beecham, Gary; Bellenguez, Celine et al.
DOI: 10.1038/gene.2013.70

JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants.

PMID: 24763718
Journal: PLoS Pathogens
Year: 2014
Reference: PLoS Pathog. 2014 Apr 24;10(4):e1004084. doi: 10.1371/journal.ppat.1004084. eCollection 2014 Apr.
Impact factor:
Publication type: Clinical guide
Authors: Albrecht, Eva; Alfredsson, Lars; Barcellos, Lisa; Booth, David; Buck, Dorothea; Comabella, Manuel; Compston, Alastair; DAlfonso, Sandra; De Jager, Philip; Fogdell-Hahn, Anna et al.
DOI: 10.1371/journal.ppat.1004084

Recommendations for the clinical use of motor evoked potentials in multiple sclerosis.

PMID: 22995526
Journal: NEUROLOGIA
Year: 2013
Reference: Neurologia. 2013 Sep;28(7):408-16. doi: 10.1016/j.nrl.2012.07.007. Epub 2012 Sep 18.
Impact factor:
Publication type: Paper in national publication
Authors: Alvarez-Cermeno, J C; Antiguedad, A; Calles, C; Costa-Frossard, L; Dinca, L; Fernandez, O; Fernandez, V; Ferrandiz, M; Izquierdo, G; Miralles, F et al.
DOI: 10.1016/j.nrl.2012.07.007

Consensus definitions and application guidelines for control groups in cerebrospinal fluid biomarker studies in multiple sclerosis.

PMID: 23695446
Journal: Multiple Sclerosis Journal
Year: 2013
Reference: Mult Scler. 2013 Nov;19(13):1802-9. doi: 10.1177/1352458513488232. Epub 2013 May 21.
Impact factor:
Publication type: Paper in international publication
Authors: Altintas, Ayse; Alvarez-Cermeno, Jose C; Bartos, Ales; Bertolotto, Antonio; Berven, Frode S; Brundin, Lou; Comabella, Manuel; Degn, Matilde; Deisenhammer, Florian; Drulovic, Jelena et al.
DOI: 10.1177/1352458513488232

[Consensus document on spasticity in patients with multiple sclerosis].

PMID: 24081891
Journal: Revista de neurologia
Year: 2013
Reference: Rev Neurol. 2013 Oct 16;57(8):359-73.
Impact factor:
Publication type: Paper in national publication
Authors: Casanova-Estruch, Bonaventura; de Andres, Clara; Fernandez, Oscar; Garcia, Inmaculada; Montalban, Xavier; Munoz-Garcia, Delicias; Oreja-Guevara, Celia et al.
DOI:

Risk acceptance in multiple sclerosis patients on natalizumab treatment.

PMID: 24340060
Journal: PLoS One
Year: 2013
Reference: PLoS One. 2013 Dec 10;8(12):e82796. doi: 10.1371/journal.pone.0082796. eCollection 2013.
Impact factor:
Publication type: Paper in international publication
Authors: Anglada, Elisenda; Arevalo, Maria Jesus; Arrambide, Georgina; Bichuetti, Denis; Castillo, Joaquin; Comabella, Manuel; Galan, Ingrid; Martin, Maria Isabel; Montalban, Xavier; Nieto Gonzalez, Pablo et al.
DOI: 10.1371/journal.pone.0082796

Optimizing parameter choice for FSL-Brain Extraction Tool (BET) on 3D T1 images in multiple sclerosis.

PMID: 22484407
Journal: NEUROIMAGE
Year: 2012
Reference: Neuroimage. 2012 Jul 16;61(4):1484-94. doi: 10.1016/j.neuroimage.2012.03.074. Epub 2012 Mar 30.
Impact factor:
Publication type: Paper in international publication
Authors: Barkhof, F; Barkhof, F; Battaglini, M; Cover, K S; de Stefano, N; de Stefano, N; Fazekas, F; Filippi, M; Frederiksen, J; Hoogstrate, W S et al.
DOI: 10.1016/j.neuroimage.2012.03.074

Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial.

PMID: 23122650
Journal: LANCET
Year: 2012
Reference: Lancet. 2012 Nov 24;380(9856):1829-39. doi: 10.1016/S0140-6736(12)61768-1. Epub 2012 Nov 1.
Impact factor:
Publication type: Paper in international publication
Authors: Achiron, Anat; Agius, Mark A; Antel, Jack; Antonelli, Licia; Arnold, Doug; Arnold, Douglas L; Ayotte, Charles; Ayuso, Guillermo Izquierdo; Barantsevich, Evgeniy R; Barkhof, Frederik et al.
DOI: 10.1016/S0140-6736(12)61768-1

DNA-based vaccines for multiple sclerosis: Current status and future directions.

PMID: 21163708
Journal: CLINICAL IMMUNOLOGY
Year: 2012
Reference: Clin Immunol. 2012 Jan;142(1):76-83. doi: 10.1016/j.clim.2010.11.011. Epub 2010 Dec 15.
Impact factor:
Publication type: Review in international publication
Authors: ; ; et al.
DOI: 10.1016/j.clim.2010.11.011

ANKRD55 and DHCR7 are novel multiple sclerosis risk loci.

PMID: 22130326
Journal: GENES AND IMMUNITY
Year: 2012
Reference: Genes Immun. 2012 Apr;13(3):253-7. doi: 10.1038/gene.2011.81. Epub 2011 Dec 1.
Impact factor:
Publication type: Paper in international publication
Authors: Alcina, A; Alloza, I; Antiguedad, A; Arroyo, R; Blanco, Y; Comabella, M; de Lapuente, A Lopez; Fedetz, M; Fernandez, O; Izquierdo, G et al.
DOI: 10.1038/gene.2011.81

Phase III dose-comparison study of glatiramer acetate for multiple sclerosis.

PMID: 21280077
Journal: ANNALS OF NEUROLOGY
Year: 2011
Reference: Ann Neurol. 2011 Jan;69(1):75-82. doi: 10.1002/ana.22316.
Impact factor:
Publication type: Paper in international publication
Authors: Absinta, Martina; Achiron, A; Agius, M; Antel, Jack; Arbizu, T; Arnold, Douglas L; Arnold, Douglas L; Arroyo, R; Bajenaru, O; Bar-Or, A et al.
DOI: 10.1002/ana.22316

A phase III study evaluating the efficacy and safety of MBP8298 in secondary progressive MS.

PMID: 21975206
Journal: NEUROLOGY
Year: 2011
Reference: Neurology. 2011 Oct 18;77(16):1551-60. Epub 2011 Oct 5.
Impact factor:
Publication type: Paper in international publication
Authors: Ahlgvist, K; Ahola, T; Airaksinen, A; Akesson, E; Albrecht, P M; Alikhani, K; Antel, J; Anten, B; Arbizu, T; Arnold, D et al.
DOI: 10.1212/WNL.0b013e318233b240

Pharmacogenomics in neurology: Current state and future steps.

PMID: 22162054
Journal: ANNALS OF NEUROLOGY
Year: 2011
Reference: Ann Neurol. 2011 Nov;70(5):684-97. doi: 10.1002/ana.22502.
Impact factor:
Publication type: Paper in international publication
Authors: Chan, Andrew; Comabella, Manuel; Pirmohamed, Munir et al.
DOI: 10.1002/ana.22502

Consensus Guidelines for CSF and Blood Biobanking for CNS Biomarker Studies.

PMID: 22096631
Journal: Multiple sclerosis international
Year: 2011
Reference: Mult Scler Int. 2011;2011:246412. Epub 2011 Jul 18.
Impact factor:
Publication type: Letter or abstract
Authors: Bennett, Jeffrey L; Berven, Frode S; Brundin, Lou; Comabella, Manuel; Deisenhammer, Florian; Federiksen, Jette L; Fleming, John O; Franciotta, Diego; Furlan, Roberto; Giovannoni, Gavin et al.
DOI: 10.1155/2011/246412

Epstein-Barr virus and multiple sclerosis: causation or association?

PMID: 21133682
Journal: Future Microbiology
Year: 2010
Reference: Future Microbiol. 2010 Nov;5:1617-9.
Impact factor:
Publication type: Editorail in international publication
Authors: Comabella, Manuel; Kakalacheva, Kristina et al.
DOI: 10.2217/fmb.10.123

Brainstem lesions in clinically isolated syndromes.

PMID: 21098409
Journal: NEUROLOGY
Year: 2010
Reference: Neurology. 2010 Nov 23;75(21):1933-8.
Impact factor:
Publication type: Paper in international publication
Authors: Arrambide, G; Auger, C; Castillo, J; Comabella, M; Edo, M C; Horga, A; Huerga, E; Mitjana, R; Montalban, X; Nos, C et al.
DOI: 10.1212/WNL.0b013e3181feb26f

A missense HTRA1 mutation expands CARASIL syndrome to the Caucasian population.

PMID: 21115960
Journal: NEUROLOGY
Year: 2010
Reference: Neurology. 2010 Nov 30;75(22):2033-5.
Impact factor:
Publication type: Editorail in international publication
Authors: Alvarez-Sabin, J; Del Rio-Espinola, A; Domingues-Montanari, S; Fernandez-Cadenas, I; Fernandez-Figueras, M T; Garcia-Patos, V; Mendioroz, M; Montaner, J; Rovira, A; Sastre-Garriga, J et al.
DOI: 10.1212/WNL.0b013e3181ff96ac

IFN-beta pharmacogenomics in multiple sclerosis.

PMID: 20712530
Journal: PHARMACOGENOMICS
Year: 2010
Reference: Pharmacogenomics. 2010 Aug;11(8):1137-48.
Impact factor:
Publication type: Review in international publication
Authors: Comabella, Manuel; Urcelay, Elena; Vandenbroeck, Koen et al.
DOI: 10.2217/pgs.10.108

Cerebrospinal fluid biomarkers in multiple sclerosis.

PMID: 19426803
Journal: NEUROBIOLOGY OF DISEASE
Year: 2009
Reference: Neurobiol Dis. 2009 Aug;35(2):117-27.
Impact factor:
Publication type: Review in international publication
Authors: Altintas, Ayse; Bennett, Jeffrey L; Berven, Frode S; Brundin, Lou; Comabella, Manuel; Deisenhammer, Florian; Federiksen, Jette L; Fleming, John O; Franciotta, Diego; Furlan, Roberto et al.
DOI: 10.1016/j.nbd.2009.04.010

Primary progressive multiple sclerosis diagnostic criteria: a reappraisal.

PMID: 19995843
Journal: MULTIPLE SCLEROSIS
Year: 2009
Reference: Mult Scler. 2009 Dec;15(12):1459-65.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1177/1352458509348422

A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking.

PMID: 19949037
Journal: NEUROLOGY
Year: 2009
Reference: Neurology. 2009 Dec 1;73(22):1914-22.
Impact factor:
Publication type: Review in international publication
Authors: Bennett, J L; Berven, F S; Brundin, L; Comabella, M; Deisenhammer, F; Fleming, J O; Franciotta, D; Frederiksen, J L; Furlan, R; Giovannoni, G et al.
DOI: 10.1212/WNL.0b013e3181c47cc2

ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis.

PMID: 19605531
Journal: BRAIN
Year: 2009
Reference: Brain. 2009 Sep;132(Pt 9):2517-30.
Impact factor:
Publication type: Paper in international publication
Authors: Chan, A; Cotte, S; Dorr, J; Gold, R; Huber, B; Koepsell, H; Konig, N; Kruse, N; Luhder, F; Montalban, X et al.
DOI: 10.1093/brain/awp164

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In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.

Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.

The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.

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Simoa HD1 equipment

We are seeking healthy volunteers for a study to find biomarkers of multiple sclerosis

We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.

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