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Clinical Neuroimmunology

The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches. 

Team

Joaquin  Justel  Pizarro

Joaquin Justel Pizarro

Research technician
Clinical Neuroimmunology
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Joaquin Castillo Justribo

Joaquin Castillo Justribo

Postdoctoral researcher
Clinical Neuroimmunology
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Jordina Beltran Valles

Jordina Beltran Valles

Administration and Management
Clinical Neuroimmunology
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José Ant. Graells Salvador

José Ant. Graells Salvador

Administration and Management
Clinical Neuroimmunology
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Lucía Gutiérrez Ruiz

Lucía Gutiérrez Ruiz

Research technician
Clinical Neuroimmunology
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M Jesus Arevalo  Navines

M Jesus Arevalo Navines

Postdoctoral researcher
Clinical Neuroimmunology
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Joaquin  Justel  Pizarro

Joaquin Justel Pizarro

Research technician
Clinical Neuroimmunology
Read more
Joaquin Castillo Justribo

Joaquin Castillo Justribo

Postdoctoral researcher
Clinical Neuroimmunology
Read more
Jordina Beltran Valles

Jordina Beltran Valles

Administration and Management
Clinical Neuroimmunology
Read more
José Ant. Graells Salvador

José Ant. Graells Salvador

Administration and Management
Clinical Neuroimmunology
Read more
Lucía Gutiérrez Ruiz

Lucía Gutiérrez Ruiz

Research technician
Clinical Neuroimmunology
Read more
M Jesus Arevalo  Navines

M Jesus Arevalo Navines

Postdoctoral researcher
Clinical Neuroimmunology
Read more

Publications

Genetic influences on disease course and severity, 30 years after a clinically isolated syndrome.

PMID: 37841069
Journal: Brain communications
Year: 2023
Reference: Brain Commun. 2023 Oct 4;5(5):fcad255. doi: 10.1093/braincomms/fcad255. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Barkhof, Frederik; Brownlee, Wallace; Castano, Carlos; Chard, Declan; Chung, Karen; Ciccarelli, Olga; Dominguez, Carlos; Gandini Wheeler-Kingshott, Claudia A M; Gramegna, Laura Ludovica; Haider, Lukas et al.
DOI: 10.1093/braincomms/fcad255

Teriflunomide and Epstein-Barr virus in a Spanish multiple sclerosis cohort: in vivo antiviral activity and clinical response.

PMID: 37841253
Journal: Frontiers in Immunology
Year: 2023
Reference: Front Immunol. 2023 Sep 29;14:1248182. doi: 10.3389/fimmu.2023.1248182. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Aladro, Yolanda; Alia, Eva Maria Guerra; Alvarez-Lafuente, Roberto; Arroyo, Rafael; Baurain, Jean-Francois; Braicu, Elena Ioana; Casanova-Peno, Ignacio; Colombo, Nicoletta; Comabella, Manuel; Costa-Frossard, Lucienne et al.
DOI: 10.3389/fimmu.2023.1248182

Impact of obesity and lung function on the efficacy of biological treatment in patients with asthma.

PMID: 37850411
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2023
Reference: J Investig Allergol Clin Immunol. 2023 Oct 18:0. doi: 10.18176/jiaci.0941.
Impact factor:
Publication type: Paper in international publication
Authors: Aladro, Yolanda; Alvarez-Lafuente, Roberto; Arroyo, Rafael; Casanova-Peno, Ignacio; Comabella, Manuel; Costa-Frossard, Lucienne; Cruz, M J; Dominguez-Mozo, Maria Inmaculada; Espejo, D; Garcia-Dominguez, Jose Manuel et al.
DOI: 10.18176/jiaci.0941

Cetuximab every 2 weeks versus standard weekly dosing administration schedule.

PMID: 37850363
Journal: Future Oncology
Year: 2023
Reference: Future Oncol. 2023 Oct 18. doi: 10.2217/fon-2023-0282.
Impact factor:
Publication type: Paper in international publication
Authors: Barkhof, Frederik; Bokemeyer, Carsten; Brownlee, Wallace; Chard, Declan; Chung, Karen; Ciardiello, Fortunato; Ciccarelli, Olga; Dubreuil, Olivier; Esser, Regina; Gandini Wheeler-Kingshott, Claudia A M et al.
DOI: 10.2217/fon-2023-0282

[Optic neuritis: aetiopathogenesis, diagnosis, prognosis and management].

PMID: 35084734
Journal: REVISTA DE NEUROLOGIA
Year: 2022
Reference: Rev Neurol. 2022 Feb 1;74(3):93-104. doi: 10.33588/rn.7403.2021473.
Impact factor: 0.87
Publication type: Review in national publication
Authors: Rodriguez-Acevedo, B, Rovira, A, Vidal-Jordana, A, Moncho, D, Pareto, D, Sastre-Garriga, J et al.
DOI: 10.33588/rn.7403.2021473

T1/T2-weighted ratio is a surrogate marker of demyelination in multiple sclerosis - Commentary.

PMID: 35067066
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Mar;28(3):357-358. doi: 10.1177/13524585211069363. Epub 2022 Jan 22.
Impact factor: 6.312
Publication type: Letter or abstract
Authors: Rovira, Alex, Pareto, Deborah et al.
DOI: 10.1177/13524585211069363

Prognosis of a second clinical event from baseline MRI in patients with a CIS: a multicenter study using a machine learning approach.

PMID: 35048162
Journal: NEURORADIOLOGY
Year: 2022
Reference: Neuroradiology. 2022 Jul;64(7):1383-1390. doi: 10.1007/s00234-021-02885-7. Epub 2022 Jan 20.
Impact factor: 2.804
Publication type: Paper in international publication
Authors: Pareto, Deborah, Garcia-Vidal, Aran, Groppa, Sergiu, Gonzalez-Escamilla, Gabriel, Rocca, Mara, Filippi, Massimo, Enzinger, Christian, Khalil, Michael, Llufriu, Sara, Sastre-Garriga, Jaume et al.
DOI: 10.1007/s00234-021-02885-7

Astrocytic outer retinal layer thinning is not a feature in AQP4-IgG seropositive neuromyelitis optica spectrum disorders.

PMID: 34711650
Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Year: 2022
Reference: J Neurol Neurosurg Psychiatry. 2022 Feb;93(2):188-195. doi: 10.1136/jnnp-2021-327412. Epub 2021 Oct 28.
Impact factor: 10.283
Publication type: Paper in international publication
Authors: Radaelli, Marta, Lu, Angelo, Zimmermann, Hanna G, Specovius, Svenja, Motamedi, Seyedamirhosein, Chien, Claudia, Bereuter, Charlotte, Lana-Peixoto, Marco A, Fontenelle, Mariana Andrade, Ashtari, Fereshteh et al.
DOI: 10.1136/jnnp-2021-327412

Blog

News

In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.

Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.

The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.

Rates

Simoa HD1 equipment

We are seeking healthy volunteers for a study to find biomarkers of multiple sclerosis

We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.

More information