Clinical Neuroimmunology
The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches.
Publications
Reliability and construct validity of three self-report questionnaires assessing dual-task difficulties in people with multiple sclerosis: an international study.
PMID: 39395710
Journal: ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
Year: 2024
Reference: Arch Phys Med Rehabil. 2024 Oct 10:S0003-9993(24)01231-0. doi: 10.1016/j.apmr.2024.08.024.
Impact factor:
Publication type: Paper in international publication
Authors: Abasiyanik, Zuhal; Ciampi, Ethel; D'Hooge, Mieke; Feys, Peter; Kahraman, Turhan; Kalron, Alon; Kos, Daphne; Meza-Murillo, Edwin-Roger; Omar, Areen; Ozakbas, Serkan et al.
DOI: 10.1016/j.apmr.2024.08.024
COVID-19 and multiple sclerosis: challenges and lessons for patient care.
PMID: 39429966
Journal: Lancet Regional Health-Europe
Year: 2024
Reference: Lancet Reg Health Eur. 2024 Aug 22;44:100979. doi: 10.1016/j.lanepe.2024.100979. eCollection 2024 Sep.
Impact factor:
Publication type: Paper in international publication
Authors: Arrambide, Georgina; Celius, Elisabeth G; Di Filippo, Massimiliano; Goletti, Delia; Killestein, Joep; Kos, Daphne; Lavorgna, Luigi; Louapre, Celine; Prosperini, Luca; Sormani, Maria Pia et al.
DOI: 10.1016/j.lanepe.2024.100979
Fluid biomarkers in multiple sclerosis: from current to future applications.
PMID: 39444698
Journal: Lancet Regional Health-Europe
Year: 2024
Reference: Lancet Reg Health Eur. 2024 Aug 22;44:101009. doi: 10.1016/j.lanepe.2024.101009. eCollection 2024 Sep.
Impact factor:
Publication type: Paper in international publication
Authors: Centonze, Diego; Di Filippo, Massimiliano; Gaetani, Lorenzo; Hegen, Harald; Kuhle, Jens; Parnetti, Lucilla; Teunissen, Charlotte E; Tintore, Mar; Villar, Luisa M; Willemse, Eline A J et al.
DOI: 10.1016/j.lanepe.2024.101009
Current and future role of MRI in the diagnosis and prognosis of multiple sclerosis.
PMID: 39444702
Journal: Lancet Regional Health-Europe
Year: 2024
Reference: Lancet Reg Health Eur. 2024 Aug 22;44:100978. doi: 10.1016/j.lanepe.2024.100978. eCollection 2024 Sep.
Impact factor:
Publication type: Paper in international publication
Authors: Barkhof, Frederik; Brownlee, Wallace; Calabrese, Massimiliano; De Stefano, Nicola; Di Filippo, Massimiliano; Filippi, Massimo; Granziera, Cristina; Preziosa, Paolo; Rocca, Maria A; Ropele, Stefan et al.
DOI: 10.1016/j.lanepe.2024.100978
Progressive multifocal leukoencephalopathy in a patient with relapsing multiple sclerosis treated with ocrelizumab.
PMID: 37485841
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2023
Reference: Eur J Neurol. 2023 Jul 24. doi: 10.1111/ene.15988.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Bravo, G; Hauser, S L; Laguillo, G; Miguela, A; Montalban, X; Puig-Casadevall, M; Quiroga Varela, A; Ramio-Torrenta, Ll; Robles-Cedeno, R; Sanchez, L et al.
DOI: 10.1111/ene.15988
Soluble mutant huntingtin drives early human pathogenesis in Huntington's disease.
PMID: 37535170
Journal: CELLULAR AND MOLECULAR LIFE SCIENCES
Year: 2023
Reference: Cell Mol Life Sci. 2023 Aug 3;80(8):238. doi: 10.1007/s00018-023-04882-w.
Impact factor:
Publication type: Paper in international publication
Authors: Alberch, Jordi; Allen, Nicholas D; Bombau, Georgina; Borras, Francesc E; Canals, Josep M; Fernandez-Garcia, Sara; Fernandez-Medina, Helena; Galofre, Mireia; Garcia-Bravo, Maria; Gomis, Cinta et al.
DOI: 10.1007/s00018-023-04882-w
Molecular signature associated with cladribine treatment in patients with multiple sclerosis.
PMID: 37559720
Journal: Frontiers in Immunology
Year: 2023
Reference: Front Immunol. 2023 Jul 25;14:1233546. doi: 10.3389/fimmu.2023.1233546. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Borras, Eva; Boschert, Ursula; Calvo-Barreiro, Laura; Comabella, Manuel; Costa-Frossard, Lucienne; Eixarch, Herena; Espejo, Carmen; Ferrer, Mireia; Fissolo, Nicolas; Montalban, Xavier et al.
DOI: 10.3389/fimmu.2023.1233546
Wall enhancement as a biomarker of intracranial aneurysm instability: a histo-radiological study.
PMID: 37589724
Journal: ACTA NEUROCHIRURGICA
Year: 2023
Reference: Acta Neurochir (Wien). 2023 Aug 17. doi: 10.1007/s00701-023-05739-8.
Impact factor:
Publication type: Paper in international publication
Authors: Arikan, Fuat; Coscojuela, Pilar; De Barros, Andrea; Dinia, Lavinia; Gandara, Dario; Gramegna, Laura Ludovica; Hernandez, David; Luzi, Michele; Martinez-Saez, Elena; Quintana, Manuel et al.
DOI: 10.1007/s00701-023-05739-8
Cross-Country Adaptation of a Psychological Flexibility Measure: The Comprehensive Assessment of Acceptance and Commitment Therapy Processes.
PMID: 35328838
Journal: International Journal of Environmental Research and Public Health
Year: 2022
Reference: Int J Environ Res Public Health. 2022 Mar 8;19(6). pii: ijerph19063150. doi: 10.3390/ijerph19063150.
Impact factor:
Publication type: Paper in international publication
Authors: Anglada, Elisenda; Galan, Ingrid; Giordano, Andrea; Giovannetti, Ambra Mara; Hoyer, Jurgen; Menendez, Rebeca; Pakenham, Kenneth Ian; Pottgen, Jana; Solari, Alessandra et al.
DOI: 10.3390/ijerph19063150
SWI as an Alternative to Contrast-Enhanced Imaging to Detect Acute MS Lesions.
PMID: 35332015
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2022
Reference: AJNR Am J Neuroradiol. 2022 Apr;43(4):534-539. doi: 10.3174/ajnr.A7474. Epub 2022 Mar 24.
Impact factor:
Publication type: Paper in international publication
Authors: Auger, C; Calderon, W; Caruana, G; de Barros, A; Montalban, X; Pessini, L M; Rovira, A; Salerno, A; Sastre-Garriga, J et al.
DOI: 10.3174/ajnr.A7474
CONCERTO: A randomized, placebo-controlled trial of oral laquinimod in relapsing-remitting multiple sclerosis.
PMID: 34378456
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Apr;28(4):608-619. doi: 10.1177/13524585211032803. Epub 2021 Aug 11.
Impact factor:
Publication type: Paper in international publication
Authors: Boyko, Alexey; Comi, Giancarlo; Dadon, Yuval; Filippi, Massimo; Halevy, Nitsan; Knappertz, Volker; Lublin, Fred D; Montalban, Xavier; Rocca, Maria A; Rubinchick, Svetlana et al.
DOI: 10.1177/13524585211032803
A smartphone sensor-based digital outcome assessment of multiple sclerosis.
PMID: 34259588
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Apr;28(4):654-664. doi: 10.1177/13524585211028561. Epub 2021 Jul 14.
Impact factor:
Publication type: Paper in international publication
Authors: Baker, Michael; Belachew, Shibeshih; Bernasconi, Corrado; Ganzetti, Marco; Gossens, Christian; Graves, Jennifer; Hauser, Stephen L; Julian, Laura; Lindemann, Michael; Lipsmeier, Florian et al.
DOI: 10.1177/13524585211028561
Alemtuzumab outcomes by age: Post hoc analysis from the randomized CARE-MS studies over 8 years.
PMID: 33476880
Journal: Multiple Sclerosis and Related Disorders
Year: 2021
Reference: Mult Scler Relat Disord. 2021 Apr;49:102717. doi: 10.1016/j.msard.2020.102717. Epub 2020 Dec 24.
Impact factor:
Publication type: Paper in international publication
Authors: Arroyo, Rafael; Baker, Darren P; Bass, Ann D; Boster, Aaron L; Boyko, Alexey N; Choudhry, Zia; Daizadeh, Nadia; Eichau, Sara; Ionete, Carolina; Limmroth, Volker et al.
DOI: 10.1016/j.msard.2020.102717
Ozanimod in relapsing multiple sclerosis: Pooled safety results from the clinical development program.
PMID: 33892317
Journal: Multiple Sclerosis and Related Disorders
Year: 2021
Reference: Mult Scler Relat Disord. 2021 Jun;51:102844. doi: 10.1016/j.msard.2021.102844. Epub 2021 Feb 15.
Impact factor:
Publication type: Paper in international publication
Authors: Arnold, Douglas L; Bar-Or, Amit; Cohen, Jeffrey A; Comi, Giancarlo; Cree, Bruce A C; Ding, Ning; Hartung, Hans Peter; Havrdova, Eva Kubala; Kappos, Ludwig; Minton, Neil et al.
DOI: 10.1016/j.msard.2021.102844
Selected Clostridia Strains from The Human Microbiota and their Metabolite, Butyrate, Improve Experimental Autoimmune Encephalomyelitis.
PMID: 33829410
Journal: Neurotherapeutics : the journal of the American So
Year: 2021
Reference: Neurotherapeutics. 2021 Apr;18(2):920-937. doi: 10.1007/s13311-021-01016-7. Epub 2021 Apr 7.
Impact factor:
Publication type: Paper in international publication
Authors: Calvo-Barreiro, Laura; Castillo, Mireia; Cornejo, Thais; Costa, Carme; Eixarch, Herena; Espejo, Carmen; Gonzalez-Lopez, Juan Jose; Guaza, Carmen; Honda, Kenya; Martinez-Cuesta, Maria Del Carmen et al.
DOI: 10.1007/s13311-021-01016-7
Cognitive impairment in multiple sclerosis: diagnosis and monitoring.
PMID: 33796947
Journal: NEUROLOGICAL SCIENCES
Year: 2021
Reference: Neurol Sci. 2021 Dec;42(12):5183-5193. doi: 10.1007/s10072-021-05165-7. Epub 2021 Apr 1.
Impact factor:
Publication type: Paper in international publication
Authors: Carreres-Polo, Joan; Eichau-Madueno, Sara; Gascon-Gimenez, Francisco; Ginestal-Lopez, Ricardo C; Higueras, Yolanda; Meca-Lallana, Virginia; Perez-Miralles, Francisco; Romero-Imbroda, Jesus; Tellez-Lara, Nieves; Vidal-Jordana, Angela et al.
DOI: 10.1007/s10072-021-05165-7
Long-term safety and efficacy of daclizumab beta in relapsing-remitting multiple sclerosis: 6-year results from the SELECTED open-label extension study.
PMID: 32451615
Journal: JOURNAL OF NEUROLOGY
Year: 2020
Reference: J Neurol. 2020 Oct;267(10):2851-2864. doi: 10.1007/s00415-020-09835-y. Epub 2020 May 25.
Impact factor:
Publication type: Paper in international publication
Authors: Castro-Borrero, Wanda; Chalkias, Spyros; Fam, Sami; Giannattasio, Giorgio; Giovannoni, Gavin; Gold, Ralf; Havrdova, Eva Kubala; Lima, Gabriel; Montalban, Xavier; Radue, Ernst-Wilhelm et al.
DOI: 10.1007/s00415-020-09835-y
Pregnancy Outcomes During the Clinical Development Program of Cladribine in Multiple Sclerosis: An Integrated Analysis of Safety.
PMID: 32447743
Journal: DRUG SAFETY
Year: 2020
Reference: Drug Saf. 2020 Jul;43(7):635-643. doi: 10.1007/s40264-020-00948-x.
Impact factor:
Publication type: Paper in international publication
Authors: Comi, Giancarlo; Cook, Stuart; Damian, Doris; Dangond, Fernando; Galazka, Andrew; Giovannoni, Gavin; Leist, Thomas; Montalban, Xavier; Schick, Regina et al.
DOI: 10.1007/s40264-020-00948-x
Value of 3T Susceptibility-Weighted Imaging in the Diagnosis of Multiple Sclerosis.
PMID: 32439639
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2020
Reference: AJNR Am J Neuroradiol. 2020 Jun;41(6):1001-1008. doi: 10.3174/ajnr.A6547. Epub 2020 May 21.
Impact factor:
Publication type: Paper in international publication
Authors: Alberich, M; Arrambide, G; Auger, C; Cappelle, S; Clarke, M A; Crescenzo, F; Evangelou, N; Montalban, X; Pareto, D; Pessini-Ferreira, L et al.
DOI: 10.3174/ajnr.A6547
12th Post-ECTRIMS Meeting: review of the novelties from the 2019 ECTRIMS Congress (II).
PMID: 32436209
Journal: REVISTA DE NEUROLOGIA
Year: 2020
Reference: Rev Neurol. 2020 Jun 1;70(11):417-429. doi: 10.33588/rn.7011.2020122.
Impact factor:
Publication type: Review in international publication
Authors: Aladro, Y; Arroyo, R; Brieva, Ll; Calles-Hernandez, M C; Carrascal, P; Comabella, M; Costa-Frossard, L; Eichau, S; Fernandez, O; Garcia-Merino, J A et al.
DOI: 10.33588/rn.7011.2020122
Brain regional volume estimations with NeuroQuant and FIRST: a study in patients with a clinically isolated syndrome.
PMID: 30834955
Journal: NEURORADIOLOGY
Year: 2019
Reference: Neuroradiology. 2019 Jun;61(6):667-674. doi: 10.1007/s00234-019-02191-3. Epub 2019 Mar 5.
Impact factor:
Publication type: Paper in international publication
Authors: Alberich, Manel; Auger, Cristina; Montalban, Xavier; Pareto, Deborah; Rovira, Alex; Sastre-Garriga, Jaume; Tintore, Mar et al.
DOI: 10.1007/s00234-019-02191-3
Menarche, pregnancies, and breastfeeding do not modify long-term prognosis in multiple sclerosis.
PMID: 30824557
Journal: NEUROLOGY
Year: 2019
Reference: Neurology. 2019 Mar 26;92(13):e1507-e1516. doi: 10.1212/WNL.0000000000007178. Epub 2019 Mar 1.
Impact factor:
Publication type: Paper in international publication
Authors: Arevalo, Maria Jesus; Arrambide, Georgina; Auger, Cristina; Castillo, Joaquin; Comabella, Manuel; Galan, Ingrid; Midaglia, Luciana; Mitjana, Raquel; Montalban, Xavier; Mulero, Patricia et al.
DOI: 10.1212/WNL.0000000000007178
Biomarkers in Multiple Sclerosis.
PMID: 29500303
Journal: Cold Spring Harbor Perspectives in Medicine
Year: 2019
Reference: Cold Spring Harb Perspect Med. 2019 Mar 1;9(3). pii: cshperspect.a029058. doi: 10.1101/cshperspect.a029058.
Impact factor:
Publication type: Review in international publication
Authors: Comabella, Manuel; Gandhi, Roopali; Paul, Anu et al.
DOI: 10.1101/cshperspect.a029058
Ocrelizumab efficacy in subgroups of patients with relapsing multiple sclerosis.
PMID: 30820738
Journal: JOURNAL OF NEUROLOGY
Year: 2019
Reference: J Neurol. 2019 May;266(5):1182-1193. doi: 10.1007/s00415-019-09248-6. Epub 2019 Feb 28.
Impact factor:
Publication type: Paper in international publication
Authors: Buffels, Regine; Cree, Bruce A C; Fiore, Damian; Garren, Hideki; Han, Jian; Hauser, Stephen L; Kappos, Ludwig; Montalban, Xavier; Papeix, Caroline; Turner, Benjamin et al.
DOI: 10.1007/s00415-019-09248-6
Spinal cord lesions: A modest contributor to diagnosis in clinically isolated syndromes but a relevant prognostic factor.
PMID: 28301287
Journal: Multiple Sclerosis Journal
Year: 2018
Reference: Mult Scler. 2018 Mar;24(3):301-312. doi: 10.1177/1352458517697830. Epub 2017 Mar 16.
Impact factor:
Publication type: Paper in international publication
Authors: Arevalo, Maria Jesus; Arrambide, Georgina; Auger, Cristina; Castillo, Joaquin; Comabella, Manuel; Galan, Ingrid; Huerga, Elena; Midaglia, Luciana; Montalban, Xavier; Mulero, Patricia et al.
DOI: 10.1177/1352458517697830
Disability progression markers over 6-12 years in interferon-beta-treated multiple sclerosis patients.
PMID: 28287331
Journal: Multiple Sclerosis Journal
Year: 2018
Reference: Mult Scler. 2018 Mar;24(3):322-330. doi: 10.1177/1352458517698052. Epub 2017 Mar 13.
Impact factor:
Publication type: Paper in international publication
Authors: Arrambide, Georgina; Auger, Cristina; Castillo, Joaquin; Comabella, Manuel; Galan, Ingrid; Montalban, Xavier; Nos, Carlos; Otero-Romero, Susana; Pujal, Berta; Rio, Jordi et al.
DOI: 10.1177/1352458517698052
The Role of the Cerebellum in Multiple Sclerosis - 150 years after Charcot.
PMID: 29477616
Journal: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
Year: 2018
Reference: Neurosci Biobehav Rev. 2018 Jun;89:85-98. doi: 10.1016/j.neubiorev.2018.02.012. Epub 2018 Feb 23.
Impact factor:
Publication type: Review in national publication
Authors: Barrantes-Freer, Alonso; Burggraaff, Jessica; D'Angelo, Egidio; D'Souza, Marcus; Dorn, Jonas; Enzinger, Christian; Filippi, Massimo; Kappos, Ludwig; Langdon, Dawn; Montalban, Xavier et al.
DOI: 10.1016/j.neubiorev.2018.02.012
Severe hypertriglyceridemia associated with teriflunomide in a patient with multiple sclerosis: A case report.
PMID: 29473796
Journal: Multiple Sclerosis Journal
Year: 2018
Reference: Mult Scler. 2018 Sep;24(10):1383-1385. doi: 10.1177/1352458518761185. Epub 2018 Feb 23.
Impact factor:
Publication type: Paper in international publication
Authors: Camara-Lemarroy, Carlos R; Castillo, Joaquin; Montalban, Xavier; Sastre-Garriga, Jaume; Tintore, Mar et al.
DOI: 10.1177/1352458518761185
Comparison between gadolinium-enhanced 2D T1-weighted gradient-echo and spin-echo sequences in the detection of active multiple sclerosis lesions on 3.0T MRI.
PMID: 27456965
Journal: EUROPEAN RADIOLOGY
Year: 2017
Reference: Eur Radiol. 2017 Apr;27(4):1361-1368. doi: 10.1007/s00330-016-4503-3. Epub 2016 Jul 25.
Impact factor: 3.967
Publication type: Paper in international publication
Authors: Aymerich, F X, Auger, C, Alcaide-Leon, P, Pareto, D, Corral, J F, Mitjana, R, Sastre-Garriga, J, Montalban, X, Rovira, A, Huerga, E et al.
DOI: 10.1007/s00330-016-4503-3
Chitinase 3-like 1 is associated with the response to interferon-beta treatment in multiple sclerosis.
PMID: 28063616
Journal: JOURNAL OF NEUROIMMUNOLOGY
Year: 2017
Reference: J Neuroimmunol. 2017 Feb 15;303:62-65. doi: 10.1016/j.jneuroim.2016.12.006. Epub 2016 Dec 18.
Impact factor: 2.536
Publication type: Paper in international publication
Authors: Matute-Blanch, Clara, Rio, Jordi, Villar, Luisa M, Midaglia, Luciana, Malhotra, Sunny, Alvarez-Cermeno, Jose C, Vidal-Jordana, Angela, Montalban, Xavier, Comabella, Manuel et al.
DOI: 10.1016/j.jneuroim.2016.12.006
Automated tissue segmentation of MR brain images in the presence of white matter lesions.
PMID: 27598104
Journal: MEDICAL IMAGE ANALYSIS
Year: 2017
Reference: Med Image Anal. 2017 Jan;35:446-457. doi: 10.1016/j.media.2016.08.014. Epub 2016 Aug 30.
Impact factor: 4.565
Publication type: Paper in international publication
Authors: Valverde, Sergi, Oliver, Arnau, Roura, Eloy, Gonzalez-Villa, Sandra, Pareto, Deborah, Vilanova, Joan C, Ramio-Torrenta, Lluis, Rovira, Alex, Llado, Xavier et al.
DOI: 10.1016/j.media.2016.08.014
Grey matter atrophy is associated with disability increase in natalizumab-treated patients.
PMID: 27354019
Journal: Multiple Sclerosis Journal
Year: 2017
Reference: Mult Scler. 2017 Apr;23(4):556-566. doi: 10.1177/1352458516656808. Epub 2016 Jul 11.
Impact factor: 4.671
Publication type: Paper in international publication
Authors: Ciampi, Ethel, Pareto, Deborah, Sastre-Garriga, Jaume, Vidal-Jordana, Angela, Tur, Carmen, Rio, Jordi, Tintore, Mar, Auger, Cristina, Rovira, Alex, Montalban, Xavier et al.
DOI: 10.1177/1352458516656808
Precision medicine in multiple sclerosis: biomarkers for diagnosis, prognosis, and treatment response.
PMID: 27075495
Journal: CURRENT OPINION IN NEUROLOGY
Year: 2016
Reference: Curr Opin Neurol. 2016 Jun;29(3):254-62. doi: 10.1097/WCO.0000000000000336.
Impact factor:
Publication type: Paper in international publication
Authors: Comabella, Manuel; Montalban, Xavier; Sastre-Garriga, Jaume et al.
DOI: 10.1097/WCO.0000000000000336
Are Leber's mitochondial DNA mutations associated with aquaporin-4 autoimmunity?
PMID: 26209590
Journal: Multiple Sclerosis Journal
Year: 2016
Reference: Mult Scler. 2016 Mar;22(3):393-4. doi: 10.1177/1352458515590649. Epub 2015 Jul 24.
Impact factor:
Publication type: Letter whit IF
Authors: Comabella, M; Dobricic, V; Drulovic, J; Dujmovic, I; Jancic, J; Jankovic, M; Novakovic, I et al.
DOI: 10.1177/1352458515590649
An uncommon first manifestation of multiple sclerosis: Tako-Tsubo cardiomyopathy.
PMID: 26993120
Journal: Multiple Sclerosis Journal
Year: 2016
Reference: Mult Scler. 2016 May;22(6):842-6. doi: 10.1177/1352458516638557. Epub 2016 Mar 18.
Impact factor:
Publication type: Paper in international publication
Authors: Juega Marino, Jesus M; Librada Escribano, Fausto; Lopez-Perez, Maria A; Marzo-Sola, Maria E; Midaglia, Luciana; Montalban, Xavier; Rovira, Alex; Sastre-Garriga, Jaume; Vidal-Jordana, Angela et al.
DOI: 10.1177/1352458516638557
Brain Volume Loss during the First Year of Interferon-Beta Treatment: Baseline Inflammation and Tissue-Specific Volume Dynamics.
PMID: 26935253
Journal: JOURNAL OF NEUROIMAGING
Year: 2016
Reference: J Neuroimaging. 2016 Sep;26(5):532-8. doi: 10.1111/jon.12337. Epub 2016 Mar 2.
Impact factor:
Publication type: Paper in international publication
Authors: Auger, Cristina; Montalban, Xavier; Pareto, Deborah; Perez-Miralles, Francisco; Rio, Jordi; Rovira, Alex; Sastre-Garriga, Jaume; Tintore, Mar; Vidal-Jordana, Angela et al.
DOI: 10.1111/jon.12337
Influence of the LILRA3 Deletion on Multiple Sclerosis Risk: Original Data and Meta-Analysis.
PMID: 26274821
Journal: PLOS ONE
Year: 2015
Reference: PLoS One. 2015 Aug 14;10(8):e0134414. doi: 10.1371/journal.pone.0134414. eCollection 2015.
Impact factor:
Publication type: Paper in international publication
Authors: Alcina, Antonio; Alvarez-Cermeno, Jose C; Arroyo, Rafael; Comabella, Manuel; Garcia-Merino, Antonio; Izquierdo, Guillermo; Malhotra, Sunny; Martinez-Rodriguez, Jose E; Matesanz, Fuencisla; Montalban, Xavier et al.
DOI: 10.1371/journal.pone.0134414
The only certain measure of the effectiveness of multiple sclerosis therapy is cerebrospinal neurofilament level-NO.
PMID: 26242692
Journal: MULT SCLER J
Year: 2015
Reference: Mult Scler. 2015 Sep;21(10):1240-2. doi: 10.1177/1352458515589774. Epub 2015 Aug 4.
Impact factor:
Publication type: Paper in international publication
Authors: Arrambide, Georgina; Espejo, Carmen; Tintore, Mar et al.
DOI: 10.1177/1352458515589774
Effects of diazoxide in multiple sclerosis: A randomized, double-blind phase 2 clinical trial.
PMID: 26405686
Journal: NEUROL RES
Year: 2015
Reference: Neurol Neuroimmunol Neuroinflamm. 2015 Sep 10;2(5):e147. doi: 10.1212/NXI.0000000000000147. eCollection 2015 Oct.
Impact factor:
Publication type: Clinical Trials
Authors: Arroyo, Rafael; Campas, Clara; Casanova, Bonaventura; Fernandez, Oscar; Garcia-Merino, Antonio; Lensch, Eckart; Martinez-Rodriguez, Jose Enrique; Meca-Lallana, Virginia; Meuth, Sven G; Montalban, Xavier et al.
DOI: 10.1212/NXI.0000000000000147
Evidence-based guidelines: MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis-establishing disease prognosis and monitoring patients.
PMID: 26369511
Journal: NAT REV NEUROL
Year: 2015
Reference: Nat Rev Neurol. 2015 Oct;11(10):597-606. doi: 10.1038/nrneurol.2015.157. Epub 2015 Sep 15.
Impact factor:
Publication type: Clinical guide
Authors: Auger, Cristina; Barkhof, Frederik; de Stefano, Nicola; Fazekas, Franz; Filippi, Massimo; Kappos, Ludwig; Miller, David; Montalban, Xavier; Polman, Chris; Rocca, Maria A et al.
DOI: 10.1038/nrneurol.2015.157
Clinical, paraclinical and serological findings in Susac syndrome: an international multicenter study.
PMID: 24606999
Journal: Journal of Neuroinflammation
Year: 2014
Reference: J Neuroinflammation. 2014 Mar 8;11:46. doi: 10.1186/1742-2094-11-46.
Impact factor:
Publication type: Paper in international publication
Authors: Aktas, Orhan; Chalk, Colin; Dorr, Jan M; Eggenberger, Eric; Fechner, Kai; Illes, Zsolt; Jarius, Sven; Kleffner, Ilka; Montalban, Xavier; Paul, Friedemann et al.
DOI: 10.1186/1742-2094-11-46
Comment on 'Fingolimod to treat severe MS after natalizumab-associated progressive multifocal leukoencephalopathy: a valid option?' Maillart et al.
PMID: 24468818
Journal: Multiple Sclerosis Journal
Year: 2014
Reference: Mult Scler. 2014 Apr;20(4):510-1. doi: 10.1177/1352458513517281. Epub 2014 Jan 27.
Impact factor:
Publication type: Paper in international publication
Authors: Montalban, Xavier; Tur, Carmen et al.
DOI: 10.1177/1352458513517281
Diagnostic value of brain chronic black holes on T1-weighted MR images in clinically isolated syndromes.
PMID: 24576831
Journal: Multiple Sclerosis Journal
Year: 2014
Reference: Mult Scler. 2014 Oct;20(11):1471-7. doi: 10.1177/1352458514526083. Epub 2014 Feb 27.
Impact factor:
Publication type: Paper in international publication
Authors: Auger, Cristina; Barkhof, Frederik; Fazekas, Franz; Filippi, Massimo; Huerga, Elena; Mitjana, Raquel; Montalban, Xavier; Polman, Chris; Rocca, Maria A; Rovira, Alex et al.
DOI: 10.1177/1352458514526083
Evaluating the response to glatiramer acetate in relapsing-remitting multiple sclerosis (RRMS) patients.
PMID: 24622350
Journal: Multiple Sclerosis Journal
Year: 2014
Reference: Mult Scler. 2014 Oct;20(12):1602-8. doi: 10.1177/1352458514527863. Epub 2014 Mar 12.
Impact factor:
Publication type: Paper in international publication
Authors: Auger, Cristina; Castillo, Joaquin; Comabella, Manuel; Montalban, Xavier; Nos, Carlos; Rio, Jordi; Rovira, Alex; Sastre-Garriga, Jaume; Tintore, Mar; Tur, Carmen et al.
DOI: 10.1177/1352458514527863
Inhibition of delta-like ligand 4 decreases Th1/Th17 response in a mouse model of multiple sclerosis.
PMID: 23466692
Journal: NEUROSCIENCE LETTERS
Year: 2013
Reference: Neurosci Lett. 2013 Apr 29;541:161-6. doi: 10.1016/j.neulet.2013.02.038. Epub 2013 Mar 1.
Impact factor:
Publication type: Paper in international publication
Authors: Costa, Carme; Eixarch, Herena; Espejo, Carmen; Godessart, Nuria; Kunkel, Steve L; Mansilla, M Jose; Montalban, Xavier et al.
DOI: 10.1016/j.neulet.2013.02.038
Semaphorins 3A and 7A: potential immune and neuroregenerative targets in multiple sclerosis.
PMID: 23419749
Journal: TRENDS IN MOLECULAR MEDICINE
Year: 2013
Reference: Trends Mol Med. 2013 Mar;19(3):157-64. doi: 10.1016/j.molmed.2013.01.003. Epub 2013 Feb 16.
Impact factor:
Publication type: Paper in international publication
Authors: Eixarch, Herena; Espejo, Carmen; Gutierrez-Franco, Ana; Montalban, Xavier et al.
DOI: 10.1016/j.molmed.2013.01.003
[Travelers attending an international vaccine center. Is the risk for the pediatric traveler increasing?]
PMID: 23402777
Journal: ANALES DE PEDIATRIA
Year: 2013
Reference: An Pediatr (Barc). 2013 Sep;79(3):142-8. doi: 10.1016/j.anpedi.2012.11.009. Epub 2013 Feb 9.
Impact factor:
Publication type: Paper in national publication
Authors: Armadans Gil, L; Calavia Garsaball, O; Campins Marti, M; Martinez-Gomez, X; Otero Romero, S; Rodrigo Pendas, J A et al.
DOI: 10.1016/j.anpedi.2012.11.009
Cellular immune responses in multiple sclerosis patients treated with interferon-beta.
PMID: 23379429
Journal: CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Year: 2013
Reference: Clin Exp Immunol. 2013 Mar;171(3):243-6. doi: 10.1111/cei.12016.
Impact factor:
Publication type: Paper in international publication
Authors: Bustamante, M F; Castro, Z; Comabella, M; Montalban, X; Rio, J; Sanchez, A et al.
DOI: 10.1111/cei.12016
Whole-body vibration training for patients with neurodegenerative disease.
PMID: 22336858
Journal: Cochrane Database of Systematic Reviews
Year: 2012
Reference: Cochrane Database Syst Rev. 2012 Feb 15;(2):CD009097. doi: 10.1002/14651858.CD009097.pub2.
Impact factor: 5.912
Publication type: Review in national publication
Authors: Roque i Figuls, Marta, Romero-Rodriguez, Daniel, Bonfill Cosp, Xavier, Santoyo Medina, Carme, Fort Vanmeerhaeghe, Azahara, Rigau Comas, David, Sitja Rabert, Merce et al.
DOI: 10.1002/14651858.CD009097.pub2
Which walking capacity tests to use in multiple sclerosis? A multicentre study providing the basis for a core set.
PMID: 21952098
Journal: Multiple Sclerosis Journal
Year: 2012
Reference: Mult Scler. 2012 Mar;18(3):364-71. doi: 10.1177/1352458511420598. Epub 2011 Sep 27.
Impact factor: 4.255
Publication type: Clinical guide
Authors: Gijbels, Domien, Dalgas, Ulrik, Romberg, Anders, de Groot, Vincent, Bethoux, Francois, Vaney, Claude, Gebara, Benoit, Medina, Carme Santoyo, Maamagi, Heigo, Rasova, Kamila et al.
DOI: 10.1177/1352458511420598
EBV-specific immune responses in patients with multiple sclerosis responding to IFN{beta} therapy.
PMID: 22020417
Journal: Multiple Sclerosis Journal
Year: 2012
Reference: Mult Scler. 2012 May;18(5):605-9. Epub 2011 Oct 21.
Impact factor: 4.255
Publication type: Paper in international publication
Authors: , , , , , et al.
DOI: 10.1177/1352458511426816
Value of NMO-IgG determination at the time of presentation as CIS.
PMID: 22551725
Journal: NEUROLOGY
Year: 2012
Reference: Neurology. 2012 May 15;78(20):1608-11. doi: 10.1212/WNL.0b013e3182563b32. Epub 2012 May 2.
Impact factor: 8.312
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1212/WNL.0b013e3182563b32
[Review of the novelties presented at the 26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (I).]
PMID: 21312169
Journal: REVISTA DE NEUROLOGIA
Year: 2011
Reference: Rev Neurol. 2011 Feb 16;52(4):227-238.
Impact factor:
Publication type: Review in national publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI:
Interferon Beta-1b for the Treatment of Primary Progressive Multiple Sclerosis: Five-Year Clinical Trial Follow-up.
PMID: 22084124
Journal: ARCHIVES OF NEUROLOGY
Year: 2011
Reference: Arch Neurol. 2011 Nov;68(11):1421-7.
Impact factor: 7.108
Publication type: Paper in international publication
Authors: Tur, Carmen, Montalban, Xavier, Tintore, Mar, Nos, Carlos, Rio, Jordi, Aymerich, Francesc Xavier, Brieva, Luis, Tellez, Nieves, Perkal, Hector, Comabella, Manuel et al.
DOI: 10.1001/archneurol.2011.241
Implication of the toll-like receptor 4 pathway in the response to interferon-beta in multiple sclerosis.
PMID: 22028223
Journal: ANNALS OF NEUROLOGY
Year: 2011
Reference: Ann Neurol. 2011 Oct;70(4):634-45. doi: 10.1002/ana.22511.
Impact factor: 10.746
Publication type: Paper in international publication
Authors: Bustamante, Marta F, Fissolo, Nicolas, Rio, Jordi, Espejo, Carmen, Costa, Carme, Mansilla, Maria Jose, Lizasoain, Ignacio, Angeles Moro, Maria, Carmen Edo, Mari, Comabella, Manuel et al.
DOI: 10.1002/ana.22511
Natural killer cell phenotype and clinical response to interferon-beta therapy in multiple sclerosis.
PMID: 21992960
Journal: CLINICAL IMMUNOLOGY
Year: 2011
Reference: Clin Immunol. 2011 Dec;141(3):348-56. Epub 2011 Sep 21.
Impact factor: 3.932
Publication type: Paper in international publication
Authors: , , , , , , et al.
DOI: 10.1016/j.clim.2011.09.006
[Demyelinating lesions as incidental findings in magnetic resonance imaging: a study of 11 cases with clinico-radiological follow-up and a review of the literature]
PMID: 20645263
Journal: REVISTA DE NEUROLOGIA
Year: 2010
Reference: Rev Neurol. 2010 Aug;51(3):129-34.
Impact factor: 1.234
Publication type: Paper in national publication
Authors: Sierra-Marcos, Alba, Mitjana, Raquel, Castillo, Joaquin, Edo, Mari Carmen, Horga-Hernandez, Alejandro, Tintore, Mar, Rio-Izquierdo, Jordi, Auger-Acosta, Cristina, Rovira, Alex, Montalban, Xavier et al.
DOI:
Clinical features of CIS of the brainstem/cerebellum of the kind seen in MS.
PMID: 19946780
Journal: JOURNAL OF NEUROLOGY
Year: 2010
Reference: J Neurol. 2010 May;257(5):742-6. Epub 2009 Nov 28.
Impact factor: 2.903
Publication type: Paper in international publication
Authors: Sastre-Garriga, Jaume, Tintore, M, Nos, C, Tur, C, Rio, J, Tellez, N, Castillo, J, Horga, A, Perkal, H, Comabella, M et al.
DOI: 10.1007/s00415-009-5403-0
Do multimodal evoked potentials add information to MRI in clinically isolated syndromes?
PMID: 19995838
Journal: MULTIPLE SCLEROSIS
Year: 2010
Reference: Mult Scler. 2010 Jan;16(1):55-61. Epub 2009 Dec 7.
Impact factor: 3.279
Publication type: Paper in international publication
Authors: Pelayo, R, Montalban, X, Minoves, T, Moncho, D, Rio, J, Nos, C, Tur, C, Castillo, J, Horga, A, Comabella, M et al.
DOI: 10.1177/1352458509352666
Plasma chitotriosidase activity in multiple sclerosis.
PMID: 19176289
Journal: CLINICAL IMMUNOLOGY
Year: 2009
Reference: Clin Immunol. 2009 May;131(2):216-22.
Impact factor: 3.606
Publication type: Paper in international publication
Authors: Vilches, A, Vilarrasa, N, Espejo, C, Montalban, X, Martin-Gallan, P, Rio, J, Dominguez, C, Comabella, M et al.
DOI: 10.1016/j.clim.2008.12.004
Plasma exchange for acute attacks of CNS demyelination: Predictors of improvement at 6 months.
PMID: 19770470
Journal: NEUROLOGY
Year: 2009
Reference: Neurology. 2009 Sep 22;73(12):949-53.
Impact factor: 7.043
Publication type: Paper in international publication
Authors: Llufriu, S, Castillo, J, Blanco, Y, Ramio-Torrenta, L, Rio, J, Valles, M, Lozano, M, Castella, M D, Calabia, J, Horga, A et al.
DOI: 10.1212/WNL.0b013e3181b879be
Measures in the first year of therapy predict the response to interferon beta in MS.
PMID: 19542263
Journal: MULTIPLE SCLEROSIS
Year: 2009
Reference: Mult Scler. 2009 Jul;15(7):848-53.
Impact factor: 3.312
Publication type: Paper in international publication
Authors: Rio, J, Castillo, J, Rovira, A, Tintore, M, Sastre-Garriga, J, Horga, A, Nos, C, Comabella, M, Aymerich, X, Montalban, X et al.
DOI: 10.1177/1352458509104591
A type I interferon signature in monocytes is associated with poor response to interferon-{beta} in multiple sclerosis.
PMID: 19741051
Journal: BRAIN
Year: 2009
Reference: Brain. 2009 Dec;132(Pt 12):3353-65.
Impact factor: 9.603
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1093/brain/awp228
News
In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.
Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.
The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.
We are seeking healthy volunteers for a study to find biomarkers of multiple sclerosis
We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.