About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches.
PMID: 38168498 Journal: Scientific Reports Year: 2024 Reference: Sci Rep. 2024 Jan 2;14(1):122. doi: 10.1038/s41598-023-49299-4. Impact factor: Publication type: Paper in international publication Authors: Baker, Mike; Bernasconi, Corrado; Bove, Riley; Butzkueven, Helmut; Capezzuto, Luca; Giovannoni, Gavin; Gossens, Christian; Julian, Laura; Kappos, Ludwig; Kriara, Lito et al. DOI: 10.1038/s41598-023-49299-4
PMID: 38218195 Journal: LANCET INFECTIOUS DISEASES Year: 2024 Reference: Lancet Infect Dis. 2024 Jan 10:S1473-3099(23)00629-1. doi: 10.1016/S1473-3099(23)00629-1. Impact factor: Publication type: Paper in international publication Authors: Almeida, Paulo Emilio Clementino; Aznar, Maria Luisa; Bosch-Nicolau, Pau; Chamorro-Tojeiro, Sandra; Correa-Oliveira, Rodrigo; de Paula, Alfredo Mauricio Batista; Del Carmen Bangher, Maria; Eloi-Santos, Silvana Maria; Espinosa-Pereiro, Juan; Fernandez, Maria L et al. DOI: 10.1016/S1473-3099(23)00629-1
PMID: 37816633 Journal: NEUROLOGY Year: 2023 Reference: Neurology. 2023 Oct 10:10.1212/WNL.0000000000207957. doi: 10.1212/WNL.0000000000207957. Impact factor: Publication type: Paper in international publication Authors: Aguayo-Ortiz, Rafael; Akgun, Katja; Arrambide, Georgina; Bassas-Freixas, Patricia; Bassas-Freixas, Patricia; Bermel, Robert A; Bernia-Petit, Eduardo; Bonfill-Orti, Montserrat; Calabresi, Peter A; Canueto, Javier et al. DOI: 10.1212/WNL.0000000000207957
PMID: 37822743 Journal: Frontiers in Microbiology Year: 2023 Reference: Front Microbiol. 2023 Sep 26;14:1220286. doi: 10.3389/fmicb.2023.1220286. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Aracil, Belen; Barkhof, Frederik; Calvi, Alberto; Calvo-Montes, Jorge; Canada-Garcia, Javier E; Canton, Rafael; Casquero-Garcia, Veronica; Cercenado, Emilia; Chard, Declan; El Mammery, Achraf et al. DOI: 10.3389/fmicb.2023.1220286
PMID: 37823722 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2023 Reference: Eur J Neurol. 2023 Oct 12. doi: 10.1111/ene.16092. Impact factor: Publication type: Paper in international publication Authors: Barkhof, Frederik; Calvi, Alberto; Chard, Declan; de la Cruz, M Jason; Eng, Edward T; Hamed, Weaam; Kanber, Baris; MacManus, David; Mendelsohn, Zoe; Prados, Ferran et al. DOI: 10.1111/ene.16092
PMID: 37847747 Journal: INTERVENTIONAL NEURORADIOLOGY Year: 2023 Reference: Interv Neuroradiol. 2023 Oct 17:15910199231207407. doi: 10.1177/15910199231207407. Impact factor: Publication type: Paper in international publication Authors: Agusti, Cristina; Araujo, Silvia G; Casabona, Jordi; Castano, Carlos; Descalzo, Vicente; Diaz, Yesika; Dominguez, Carlos; Fernandez, Gema; Garcia-Perez, Jorge; Garcia-Perez, Jorge et al. DOI: 10.1177/15910199231207407
PMID: 35048162 Journal: NEURORADIOLOGY Year: 2022 Reference: Neuroradiology. 2022 Jul;64(7):1383-1390. doi: 10.1007/s00234-021-02885-7. Epub 2022 Jan 20. Impact factor: Publication type: Paper in international publication Authors: Enzinger, Christian; Filippi, Massimo; Garcia-Vidal, Aran; Gonzalez-Escamilla, Gabriel; Groppa, Sergiu; Khalil, Michael; Llufriu, Sara; Pareto, Deborah; Rocca, Mara; Rovira, Alex et al. DOI: 10.1007/s00234-021-02885-7
PMID: 34711650 Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Year: 2022 Reference: J Neurol Neurosurg Psychiatry. 2022 Feb;93(2):188-195. doi: 10.1136/jnnp-2021-327412. Epub 2021 Oct 28. Impact factor: Publication type: Paper in international publication Authors: Aktas, Orhan; Albrecht, Philipp; Altintas, Ayse; Asgari, Nasrin; Ashtari, Fereshteh; Bereuter, Charlotte; Bichuetti, Denis Bernardi; Brandt, Alexander U; Chien, Claudia; Cobo-Calvo, Alvaro et al. DOI: 10.1136/jnnp-2021-327412
PMID: 35001198 Journal: JOURNAL OF NEUROLOGY Year: 2022 Reference: J Neurol. 2022 Apr;269(4):1764-1772. doi: 10.1007/s00415-021-10958-z. Epub 2022 Jan 10. Impact factor: Publication type: Paper in international publication Authors: Arrambide, Georgina; Auger, Cristina; Carbonell, Pere; Cardenas-Robledo, Simon; Castillo, Joaquin; Castillo, Mireia; Cobo-Calvo, Alvaro; Comabella, Manuel; Espejo, Carmen; Galan, Ingrid et al. DOI: 10.1007/s00415-021-10958-z
PMID: 34800172 Journal: JOURNAL OF NEUROLOGY Year: 2022 Reference: J Neurol. 2022 Jan;269(1):460. doi: 10.1007/s00415-021-10906-x. Impact factor: Publication type: Letter or abstract Authors: Arrambide, Georgina; Auger, Cristina; Castillo, Joaquim; Cobo-Calvo, Alvaro; Comabella, Manuel; Galan, Ingrid; Gasperini, Claudio; Midaglia, Luciana; Montalban, Xavier; Nos, Carlos et al. DOI: 10.1007/s00415-021-10906-x
PMID: 32561334 Journal: NEUROLOGIA Year: 2021 Reference: Neurologia. 2021 Jan - Feb;36(1):50-60. doi: 10.1016/j.nrl.2020.02.006. Epub 2020 Jun 17. Impact factor: Publication type: Paper in national publication Authors: Ara, J R; Blanco, Y; Brieva, L; Calles, C; Carmona, O; Casanova, V; Costa-Frossard, L; Eichau, S; Garcia-Merino, J A; Garcia-Vidal, C et al. DOI: 10.1016/j.nrl.2020.02.006
PMID: 32959427 Journal: ANNALS OF NEUROLOGY Year: 2021 Reference: Ann Neurol. 2021 Jan;89(1):30-41. doi: 10.1002/ana.25909. Epub 2020 Oct 15. Impact factor: Publication type: Paper in international publication Authors: Arrambide, Georgina; Audoin, Bertrand; Ayrignac, Xavier; Biotti, Damien; Bourre, Bertrand; Ciron, Jonathan; Cobo-Calvo, Alvaro; Cohen, Mikael; Collongues, Nicolas; De Seze, Jerome et al. DOI: 10.1002/ana.25909
PMID: 33091175 Journal: ANNALS OF NEUROLOGY Year: 2021 Reference: Ann Neurol. 2021 Jan;89(1):13-23. doi: 10.1002/ana.25927. Epub 2020 Nov 4. Impact factor: Publication type: Review in international publication Authors: Absinta, Martina; Bar-Or, Amit; Battistini, Luca; Bennet, Jeffrey L; Bergman, Joakim; Calabrese, Massimiliano; Comi, Giancarlo; Correale, Jorge; Dornmair, Klaus; Edan, Gilles et al. DOI: 10.1002/ana.25927
PMID: 33293459 Journal: Neurology-Neuroimmunology & Neuroinflammation Year: 2021 Reference: Neurol Neuroimmunol Neuroinflamm. 2020 Dec 8;8(1). pii: 8/1/e921. doi: 10.1212/NXI.0000000000000921. Print 2021 Jan. Impact factor: Publication type: Review in international publication Authors: Comabella, Manuel; Montalban, Xavier; Pinteac, Rucsanda; Pinteac, Rucsanda et al. DOI: 10.1212/NXI.0000000000000921
PMID: 32034114 Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Year: 2020 Reference: J Neurol Neurosurg Psychiatry. 2020 Apr;91(4):388-391. doi: 10.1136/jnnp-2019-322369. Epub 2020 Feb 7. Impact factor: Publication type: Paper in international publication Authors: Barkhof, Frederik; Chard, Declan T; Chung, Karen; DeLuca, Gabriele C; Dos Passos, Giordani; Enzinger, Christian; Gasperini, Claudio; Geraldes, Ruth; Hagens, Marloes; Huerga, Elena et al. DOI: 10.1136/jnnp-2019-322369
PMID: 32023868 Journal: International Journal of Environmental Research and Public Health Year: 2020 Reference: Int J Environ Res Public Health. 2020 Jan 31;17(3). pii: ijerph17030886. doi: 10.3390/ijerph17030886. Impact factor: Publication type: Paper in international publication Authors: Alves-Guerreiro, Jose; Asch, Paul Van; Baert, Ilse; Bakalidou, Daphne; Beiske, Antonie; Cattaneo, Davide; Dimitrova, Erieta; Feys, Peter; Freeman, Jenny; Habek, Mario et al. DOI: 10.3390/ijerph17030886
PMID: 32028116 Journal: Multiple Sclerosis and Related Disorders Year: 2020 Reference: Mult Scler Relat Disord. 2020 May;40:101973. doi: 10.1016/j.msard.2020.101973. Epub 2020 Jan 31. Impact factor: Publication type: Letter or abstract Authors: Bajana, I; Escola-Verge, L; Guillen, E; Len, O; Midaglia, L; Montalban, X; Romero, A; Salcedo, M T; Tintore, M; Viladomiu, L et al. DOI: 10.1016/j.msard.2020.101973
PMID: 32002905 Journal: Methods in molecular biology (Clifton, N.J.) Year: 2020 Reference: Methods Mol Biol. 2020;2110:115-128. doi: 10.1007/978-1-0716-0255-3_8. Impact factor: Publication type: Paper in international publication Authors: Casos, Kelly; Costa, Cristina; Galinanes, Manuel et al. DOI: 10.1007/978-1-0716-0255-3_8
PMID: 30834955 Journal: NEURORADIOLOGY Year: 2019 Reference: Neuroradiology. 2019 Jun;61(6):667-674. doi: 10.1007/s00234-019-02191-3. Epub 2019 Mar 5. Impact factor: 2.504 Publication type: Paper in international publication Authors: Pareto, Deborah, Sastre-Garriga, Jaume, Alberich, Manel, Auger, Cristina, Tintore, Mar, Montalban, Xavier, Rovira, Alex et al. DOI: 10.1007/s00234-019-02191-3
PMID: 30555005 Journal: NeuroImage-Clinical Year: 2019 Reference: Neuroimage Clin. 2019;21:101638. doi: 10.1016/j.nicl.2018.101638. Epub 2018 Dec 10. Impact factor: 3.943 Publication type: Paper in international publication Authors: Valverde, Sergi, Salem, Mostafa, Cabezas, Mariano, Pareto, Deborah, Vilanova, Joan C, Ramio-Torrenta, Lluis, Rovira, Alex, Salvi, Joaquim, Oliver, Arnau, Llado, Xavier et al. DOI: 10.1016/j.nicl.2018.101638
PMID: 30824557 Journal: NEUROLOGY Year: 2019 Reference: Neurology. 2019 Mar 26;92(13):e1507-e1516. doi: 10.1212/WNL.0000000000007178. Epub 2019 Mar 1. Impact factor: 8.689 Publication type: Paper in international publication Authors: Comabella, Manuel, Nos, Carlos, Arevalo, Maria Jesus, Vidal-Jordana, Angela, Castillo, Joaquin, Rodriguez, Breogan, Midaglia, Luciana, Mulero, Patricia, Mitjana, Raquel, Auger, Cristina et al. DOI: 10.1212/WNL.0000000000007178
PMID: 30776698 Journal: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY Year: 2019 Reference: Seizure. 2019 Mar;66:31-35. doi: 10.1016/j.seizure.2019.02.004. Epub 2019 Feb 8. Impact factor: 2.765 Publication type: Paper in international publication Authors: Toledo, Manuel, Sarria, Silvana, Abraira, Laura, Gramegna, Laura Ludovica, Quintana, Manuel, Santamarina, Estevo, Salas-Puig, Javier, Rovira, Alex et al. DOI: 10.1016/j.seizure.2019.02.004
PMID: 29251340 Journal: REVISTA DE NEUROLOGIA Year: 2018 Reference: Rev Neurol. 2018 Jan 1;66(1):25-32. Impact factor: Publication type: Review in national publication Authors: Midaglia, L; Montalban, X; Mora, L; Mulero, P; Sastre-Garriga, J et al. DOI: 10.33588/rn.6601.2017213
PMID: 29157398 Journal: NEUROLOGIC CLINICS Year: 2018 Reference: Neurol Clin. 2018 Feb;36(1):173-183. doi: 10.1016/j.ncl.2017.08.011. Impact factor: Publication type: Review in international publication Authors: Vidal-Jordana, Angela et al. DOI: 10.1016/j.ncl.2017.08.011
PMID: 29359174 Journal: Neurology-Neuroimmunology & Neuroinflammation Year: 2018 Reference: Neurol Neuroimmunol Neuroinflamm. 2018 Jan 17;5(2):e436. doi: 10.1212/NXI.0000000000000436. eCollection 2018 Mar. Impact factor: Publication type: Paper in international publication Authors: Alcaide-Leon, Paula; Bharatha, Aditya; Casserly, Courtney; Cybulsky, Kateryna; Hohol, Marika; Leung, General; Montalban, Xavier; Oh, Jiwon; Sankar, Stephanie; Selchen, Daniel et al. DOI: 10.1212/NXI.0000000000000436
PMID: 30367633 Journal: Journal of Neuroinflammation Year: 2018 Reference: J Neuroinflammation. 2018 Oct 26;15(1):296. doi: 10.1186/s12974-018-1336-9. Impact factor: 5.193 Publication type: Paper in international publication Authors: Montalban, Xavier, Malhotra, Sunny, Villar, Luisa M, Costa, Carme, Midaglia, Luciana, Cubedo, Marta, Medina, Silvia, Fissolo, Nicolas, Rio, Jordi, Castillo, Joaquin et al. DOI: 10.1186/s12974-018-1336-9
PMID: 26847633 Journal: NEURORADIOLOGY Year: 2016 Reference: Neuroradiology. 2016 May;58(5):467-74. doi: 10.1007/s00234-016-1654-5. Epub 2016 Feb 4. Impact factor: 2.274 Publication type: Paper in international publication Authors: Aymerich, F X, Auger, C, Tintore, M, Montalban, X, Rovira, A, Sastre-Garriga, J, Pareto, D et al. DOI: 10.1007/s00234-016-1654-5
PMID: 26227167 Journal: NEURORADIOLOGY Year: 2015 Reference: Neuroradiology. 2015 Oct;57(10):1031-43. doi: 10.1007/s00234-015-1552-2. Epub 2015 Jul 31. Impact factor: 2.485 Publication type: Paper in international publication Authors: Roura, Eloy, Oliver, Arnau, Cabezas, Mariano, Valverde, Sergi, Pareto, Deborah, Vilanova, Joan C, Ramio-Torrenta, Lluis, Rovira, Alex, Llado, Xavier et al. DOI: 10.1007/s00234-015-1552-2
PMID: 25583834 Journal: Multiple Sclerosis Journal Year: 2015 Reference: Mult Scler. 2015 Feb;21(2):132-3. doi: 10.1177/1352458514565415. Epub 2015 Jan 12. Impact factor: 4.822 Publication type: Paper in international publication Authors: Rio, Jordi et al. DOI: 10.1177/1352458514565415
PMID: 25670046 Journal: REVISTA DE NEUROLOGIA Year: 2015 Reference: Rev Neurol. 2015 Feb 16;60(4):164-8. Impact factor: 0.83 Publication type: Paper in national publication Authors: Tintore, Mar, Sastre-Garriga, Jaume, Vidal, Anka, Castillo, Joaquin, Montalban, Xavier, Auger, Cristina, Rovira, Alex, Rio, Jordi, Marti, Gloria et al. DOI:
PMID: 25778697 Journal: Multiple Sclerosis Journal Year: 2015 Reference: Mult Scler. 2015 Dec;21(14):1802-10. doi: 10.1177/1352458515575338. Epub 2015 Mar 16. Impact factor: 4.822 Publication type: Paper in international publication Authors: Simon, Eva, Castillo, Joaquin, Palavra, Filipe, Mitjana, Raquel, Auger, Cristina, Rovira, Alex, Montalban, Xavier, Vidal-Jordana, Angela, Galan, Ingrid, Nos, Carlos et al. DOI: 10.1177/1352458515575338
In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.
Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.
The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.
Simoa HD1 equipment
We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.
