About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches.
PMID: 37861218 Journal: NEW ENGLAND JOURNAL OF MEDICINE Year: 2023 Reference: N Engl J Med. 2023 Oct 20. doi: 10.1056/NEJMoa2307980. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan Gonzalez; Ahn, Myung-Ju; Akamatsu, Hiroaki; Albillos, Agustin; Amitrano, Lucio; Anderson, Erik S; Balcar, Lorenz; Blackhall, Fiona; Borghaei, Hossein; Bosch, Jaime et al. DOI: 10.1056/NEJMoa2307980
PMID: 37906292 Journal: EUROPEAN SPINE JOURNAL Year: 2023 Reference: Eur Spine J. 2023 Oct 31. doi: 10.1007/s00586-023-07988-8. Impact factor: Publication type: Other (letters to the editor, abstracts, corrigendum, etc.) Authors: Alanay, Ahmet; Baldinotti, Anna; Bar-Or, Amit; Barkhof, Frederik; Haddad, Sleiman; Hauser, Stephen L; Kappos, Ludwig; Kleinstuck, Frank; Koendgen, Harold; Leppert, David et al. DOI: 10.1007/s00586-023-07988-8
PMID: 37906326 Journal: JOURNAL OF NEUROLOGY Year: 2023 Reference: J Neurol. 2023 Oct 31. doi: 10.1007/s00415-023-11943-4. Impact factor: Publication type: Paper in international publication Authors: Baldinotti, Anna; Bar-Or, Amit; Barkhof, Frederik; Hauser, Stephen L; Kappos, Ludwig; Koendgen, Harold; Leppert, David; Li, David K B; Montalban, Xavier; Nedelcu, Marius et al. DOI: 10.1007/s00415-023-11943-4
PMID: 37940409 Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Year: 2023 Reference: J Neurol Neurosurg Psychiatry. 2023 Nov 8:jnnp-2023-332251. doi: 10.1136/jnnp-2023-332251. Impact factor: Publication type: Paper in international publication Authors: Abdelhak, Ahmed; Alvarez-Lafuente, Roberto; Anton-Galindo, Ester; Bachhuber, Franziska; Benkert, Pascal; Berek, Klaus; Blanco, Yolanda; Cabana-Dominguez, Judit; Castillo-Trivino, Tamara; Comabella, Manuel et al. DOI: 10.1136/jnnp-2023-332251
PMID: 34716250 Journal: NEUROLOGY Year: 2022 Reference: Neurology. 2022 Jan 4;98(1):e1-e14. doi: 10.1212/WNL.0000000000013016. Epub 2021 Oct 29. Impact factor: Publication type: Paper in international publication Authors: Amato, Maria Pia; Barkhof, Frederik; Brownlee, Wallace; Ciccarelli, Olga; Comi, Giancarlo; Costa, Gloria Dalla; Cramer, Stig P; Drulovic, Jelena; Enzinger, Christian; Fainardi, Enrico et al. DOI: 10.1212/WNL.0000000000013016
PMID: 33870790 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Jan;28(1):71-81. doi: 10.1177/13524585211010082. Epub 2021 Apr 19. Impact factor: Publication type: Paper in international publication Authors: Auger, Cristina; Benkert, Pascal; Clarke, Margareta A; Comabella, Manuel; Fissolo, Nicolas; Granziera, Cristina; Kuhle, Jens; Montalban, Xavier; Pareto, Deborah; Pinteac, Rucsanda et al. DOI: 10.1177/13524585211010082
PMID: 33764197 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Jan;28(1):132-138. doi: 10.1177/13524585211005339. Epub 2021 Mar 25. Impact factor: Publication type: Paper in international publication Authors: Amato, Maria Pia; Derfuss, Tobias; Fonderico, Mattia; Hemmer, Bernhard; Portaccio, Emilio; Selmaj, Krzysztof; Stankoff, Bruno; Tintore, Mar et al. DOI: 10.1177/13524585211005339
PMID: 34927702 Journal: REVISTA DE NEUROLOGIA Year: 2022 Reference: Rev Neurol. 2022 Jan 1;74(1):22-34. doi: 10.33588/rn.7401.2021163. Impact factor: Publication type: Review in national publication Authors: Arrambide, G; Cobo-Calvo, A; Sepulveda, M et al. DOI: 10.33588/rn.7401.2021163
PMID: 34607924 Journal: NEUROLOGY Year: 2021 Reference: Neurology. 2021 Nov 23;97(21):989-999. doi: 10.1212/WNL.0000000000012884. Epub 2021 Oct 4. Impact factor: 9.91 Publication type: Paper in international publication Authors: Barkhof, Frederik, Vrenken, Hugo, Jenkinson, Mark, Pham, Dzung, Guttmann, Charles R G, Pareto, Deborah, Paardekooper, Michel, de Sitter, Alexandra, Rocca, Maria A, Wottschel, Viktor et al. DOI: 10.1212/WNL.0000000000012884
PMID: 34610987 Journal: NEUROLOGY Year: 2021 Reference: Neurology. 2021 Nov 9;97(19):e1870-e1885. doi: 10.1212/WNL.0000000000012753. Epub 2021 Oct 5. Impact factor: 9.91 Publication type: Paper in international publication Authors: Pirmani, Ashkan, Simpson-Yap, Steve, De Brouwer, Edward, Kalincik, Tomas, Rijke, Nick, Hillert, Jan A, Walton, Clare, Edan, Gilles, Moreau, Yves, Spelman, Tim et al. DOI: 10.1212/WNL.0000000000012753
PMID: 34586594 Journal: Translational Stroke Research Year: 2021 Reference: Transl Stroke Res. 2021 Sep 29. pii: 10.1007/s12975-021-00946-w. doi: 10.1007/s12975-021-00946-w. Impact factor: 6.829 Publication type: Paper in international publication Authors: Ribo, Marc, Juega, Jesus, Palacio-Garcia, Carlos, Rodriguez, Maite, Deck, Matias, Rodriguez-Luna, David, Requena, Manuel, Garcia-Tornel, Alvaro, Rodriguez-Villatoro, Noelia, Rubiera, Marta et al. DOI: 10.1007/s12975-021-00946-w
PMID: 34556662 Journal: Scientific Data Year: 2021 Reference: Sci Data. 2021 Sep 23;8(1):251. doi: 10.1038/s41597-021-01044-0. Impact factor: 6.444 Publication type: Letter or abstract Authors: Horak, Tomas, Descoteaux, Maxime, de Sousa, Paulo Loureiro, Dostal, Marek, Doyon, Julien, Dvorak, Adam, Eippert, Falk, Epperson, Karla R, Epperson, Kevin S, Freund, Patrick et al. DOI: 10.1038/s41597-021-01044-0
PMID: 31987648 Journal: Neurologia (Barcelona, Spain) Year: 2020 Reference: Neurologia (Engl Ed). 2020 Jan 25:S0213-4853(19)30146-X. doi: 10.1016/j.nrl.2019.11.003. Impact factor: Publication type: Paper in national publication Authors: Alvarez Cermeno, J C; Arnal Garcia, C; Arroyo Gonzalez, R; Brieva Ruiz, L; Calles Hernandez, C; Eichau Madueno, S; Fernandez Fernandez, O; Fernandez-Prada, M; Garcia Merino, A; Garcia Vazquez, E et al. DOI: 10.1016/j.nrl.2019.11.003
PMID: 31960250 Journal: NEUROLOGICAL SCIENCES Year: 2020 Reference: Neurol Sci. 2020 Jun;41(6):1513-1519. doi: 10.1007/s10072-019-04230-6. Epub 2020 Jan 20. Impact factor: Publication type: Paper in international publication Authors: Alonso Serena, Marina; Alonso, Ricardo; Alvez Pinheiro, Amelia; Balbuena, Maria E; Barboza, Andres G; Bestoso, Santiago; Blanche, Jorge; Blaya, Patricio A; Burgos, Marcos; Cabrera, Lorena M et al. DOI: 10.1007/s10072-019-04230-6
PMID: 31965896 Journal: Multiple Sclerosis Journal Year: 2020 Reference: Mult Scler. 2020 Apr;26(5):605-608. doi: 10.1177/1352458519888178. Epub 2020 Jan 22. Impact factor: Publication type: Paper in international publication Authors: Graves, Jennifer S; Montalban, Xavier et al. DOI: 10.1177/1352458519888178
PMID: 33424479 Journal: International journal of MS care Year: 2020 Reference: Int J MS Care. 2020 Nov-Dec;22(6):247-255. doi: 10.7224/1537-2073.2020-014. Epub 2020 Sep 14. Impact factor: 0 Publication type: Paper in international publication Authors: Coote, Susan, Santoyo-Medina, Carme, Kalron, Alon, Gunn, Hilary, Quinn, Gillian, Comber, Laura et al. DOI: 10.7224/1537-2073.2020-014
PMID: 29645067 Journal: REVISTA DE NEUROLOGIA Year: 2018 Reference: Rev Neurol. 2018 Apr 16;66(8):253. Impact factor: 0.601 Publication type: Editorail in international publication Authors: Rio, J et al. DOI:
PMID: 29579644 Journal: Multiple Sclerosis and Related Disorders Year: 2018 Reference: Mult Scler Relat Disord. 2018 May;22:59-67. doi: 10.1016/j.msard.2018.03.005. Epub 2018 Mar 14. Impact factor: 3.199 Publication type: Paper in international publication Authors: Rasova, Kamila, Pavlikova, Marketa, Salci, Yeliz, Martinkova, Patricia, Freeman, Jenny, Drabinova, Adela, Erosheva, Elena, Cattaneo, Davide, Jonsdottir, Johanna, Baert, Ilse et al. DOI: 10.1016/j.msard.2018.03.005
PMID: 29571860 Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES Year: 2018 Reference: J Neurol Sci. 2018 Apr 15;387:179-186. doi: 10.1016/j.jns.2018.02.026. Epub 2018 Feb 16. Impact factor: 2.448 Publication type: Paper in international publication Authors: Jensen, E, Baert, I, Romberg, A, Santoyo Medina, C, Gebara, B, Maertens de Noordhout, B, Knuts, K, Bethoux, F, Rasova, K, Severijns, D et al. DOI: 10.1016/j.jns.2018.02.026
PMID: 28643544 Journal: Multiple Sclerosis Journal Year: 2018 Reference: Mult Scler. 2018 Mar;24(3):358-360. doi: 10.1177/1352458517711569. Epub 2017 Jun 23. Impact factor: 5.28 Publication type: Paper in international publication Authors: Mulero, Patricia, Auger, Cristina, Parolin, Laura, Fonseca, Elena, Requena, Manuel, Rio, Jordi, Tintore, Mar, Rovira, Alex, Montalban, Xavier et al. DOI: 10.1177/1352458517711569
PMID: 25586466 Journal: BRAIN Year: 2015 Reference: Brain. 2015 Mar;138(Pt 3):644-52. doi: 10.1093/brain/awu388. Epub 2015 Jan 12. Impact factor: 9.196 Publication type: Paper in international publication Authors: Chan, Andrew, Martinelli-Boneschi, Filippo, Garcia-Merino, Antonio, Montalban, Xavier, Comabella, Manuel, Drulovic, Jelena, Lechner-Scott, Jeannette, Brassat, David, Malhotra, Sunny, Rio, Jordi et al. DOI: 10.1093/brain/awu388
In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.
Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.
The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.
Simoa HD1 equipment
We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.
