Skip to main content

Clinical Research/Innovation in Pneumonia & Sepsis (CRIPS)

CRIPS is a research group focusing on severe acute respiratory infections and sepsis. 

The objective is to develop projects on clinical and translational research in hospital-acquired pneumonia, community-acquired pneumonia, and severe viral respiratory infections, such as influenza and COVID-19. CRIPS also develop epidemiological studies focused on risk and prognostic factors for multi-resistant pathogens, validation of ventilator-associated events in ventilated adult and pediatric patients, incorporating artificial intelligence techniques. It also highlights evidence-based medicine (EBM) research, evaluating therapies and prevention strategies and participating in the formulation of clinical practice guidelines, as part of CIBERES and the European Society for Clinical Microbiology and Infections. The EBM research focuses on knowledge translation to get research findings to the point of decision making, providing health-related recommendations, focusing on clinical research and relevance of care. 

CRIPS collaborate on a Local (UIC, IDIAP), National (CIBERES), and International level (CHU Nimes, Uolo University, ISARIC and Pneumo-Inspire Networks).

Publications

Nebulized Antibiotics for Healthcare- and Ventilator-Associated Pneumonia.

PMID: 35042259
Journal: SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE
Year: 2022
Reference: Semin Respir Crit Care Med. 2022 Apr;43(2):255-270. doi: 10.1055/s-0041-1740340. Epub 2022 Jan 18.
Impact factor: 3.119
Publication type: Paper in international publication
Authors: Boisson, Matthieu, Bougle, Adrien, Sole-Lleonart, Candela, Dhanani, Jayesh, Arvaniti, Kostoula, Rello, Jordi, Rouby, Jean-Jacques, Mimoz, Olivier et al.
DOI: 10.1055/s-0041-1740340

Differences between genetic dilated cardiomyopathy and myocarditis in children presenting with severe cardiac dysfunction.

PMID: 34286374
Journal: EUROPEAN JOURNAL OF PEDIATRICS
Year: 2022
Reference: Eur J Pediatr. 2022 Jan;181(1):287-294. doi: 10.1007/s00431-021-04175-z. Epub 2021 Jul 20.
Impact factor: 3.183
Publication type: Paper in international publication
Authors: Fernandez-Alvarez, Paula, Codina-Sola, Marta, Balcells, Joan, Izquierdo-Blasco, Jaume, Gran, Ferran, Garrido, Marta, Dolader, Paola, Fidalgo, Andrea, Navarro, Alexandra, Sabate-Rotes, Anna et al.
DOI: 10.1007/s00431-021-04175-z

Anxiety among front-line health-care workers supporting patients with COVID-19: A global survey.

PMID: 33418193
Journal: GENERAL HOSPITAL PSYCHIATRY
Year: 2021
Reference: Gen Hosp Psychiatry. 2021 Jan-Feb;68:90-96. doi: 10.1016/j.genhosppsych.2020.12.010. Epub 2020 Dec 20.
Impact factor: 3.238
Publication type: Paper in international publication
Authors: Cag, Yasemin, Erdem, Hakan, Gormez, Aynur, Ankarali, Handan, Hargreaves, Sally, Ferreira-Coimbra, Joao, Rubulotta, Francesca, Belliato, Mirko, Berger-Estilita, Joana, Pelosi, Paolo et al.
DOI: 10.1016/j.genhosppsych.2020.12.010

The Spanish Version of the Fear of Kidney Failure Questionnaire: Validity, Reliability, and Characterization of Living Donors With the Highest Fear of Kidney Failure.

PMID: 33490380
Journal: Transplantation direct
Year: 2021
Reference: Transplant Direct. 2021 Jan 15;7(2):e655. doi: 10.1097/TXD.0000000000001100. eCollection 2021 Feb.
Impact factor: 0
Publication type: Paper in international publication
Authors: Torres, Xavier, Menjivar, Ana, Bailles, Eva, Rangil, Teresa, Delgado, Isabel, Musquera, Mireia, Paredes, David, Martinez, Montserrat, Avinyo, Nuria, Valles, Carmen et al.
DOI: 10.1097/TXD.0000000000001100

Lung and kidney perfusion deficits diagnosed by dual-energy computed tomography in patients with COVID-19-related systemic microangiopathy.

PMID: 32860146
Journal: EUROPEAN RADIOLOGY
Year: 2021
Reference: Eur Radiol. 2021 Feb;31(2):1090-1099. doi: 10.1007/s00330-020-07155-3. Epub 2020 Aug 29.
Impact factor: 5.315
Publication type: Paper in international publication
Authors: Akata, Deniz, Rello, Jordi, Idilman, Ilkay S, Telli Dizman, Gulcin, Ardali Duzgun, Selin, Irmak, Ilim, Karcaaltincaba, Musturay, Inkaya, Ahmet Cagkan, Demirkazik, Figen, Durhan, Gamze et al.
DOI: 10.1007/s00330-020-07155-3

Aspiration Risk Factors, Microbiology, and Empiric Antibiotics for Patients Hospitalized With Community-Acquired Pneumonia.

PMID: 32687909
Journal: CHEST
Year: 2021
Reference: Chest. 2021 Jan;159(1):58-72. doi: 10.1016/j.chest.2020.06.079. Epub 2020 Jul 17.
Impact factor: 9.41
Publication type: Paper in international publication
Authors: Bashi, Jules, Diaz, Ariel Cordon, de Vedia, Lautaro, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M, Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina et al.
DOI: 10.1016/j.chest.2020.06.079

Fetal Transient Skin Edema in Two Pregnant Women With Coronavirus Disease 2019 (COVID-19).

PMID: 32649505
Journal: OBSTETRICS AND GYNECOLOGY
Year: 2020
Reference: Obstet Gynecol. 2020 Nov;136(5):1016-1020. doi: 10.1097/AOG.0000000000004059.
Impact factor: 5.524
Publication type: Paper in international publication
Authors: Garcia-Manau, Pablo, Garcia-Ruiz, Itziar, Rodo, Carlota, Sulleiro, Elena, Maiz, Nerea, Catalan, Marina, Fernandez-Hidalgo, Nuria, Balcells, Joan, Anton, Andres, Carreras, Elena et al.
DOI: 10.1097/AOG.0000000000004059

"Management of Community-Acquired Pneumonia in Immunocompromised Adults: A Consensus Statement Regarding Initial Strategies".

PMID: 32561442
Journal: CHEST
Year: 2020
Reference: Chest. 2020 Nov;158(5):1896-1911. doi: 10.1016/j.chest.2020.05.598. Epub 2020 Jun 16.
Impact factor: 8.308
Publication type: Review in international publication
Authors: Azoulay, Elie, Ramirez, Julio A, Musher, Daniel M, Evans, Scott E, Dela Cruz, Charles, Crothers, Kristina A, Hage, Chadi A, Aliberti, Stefano, Anzueto, Antonio, Arancibia, Francisco et al.
DOI: 10.1016/j.chest.2020.05.598

Etiologies and Outcomes of Acute Respiratory Failure in Solid Organ Transplant Recipients: Insight Into the EFRAIM Multicenter Cohort.

PMID: 32499142
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2020
Reference: Transplant Proc. 2020 Dec;52(10):2980-2987. doi: 10.1016/j.transproceed.2020.02.170. Epub 2020 Jun 1.
Impact factor: 0.784
Publication type: Paper in international publication
Authors: Messika, Jonathan, Darmon, Michael, Mal, Herve, Pickkers, Peter, Soares, Marcio, Canet, Emmanuel, Rello, Jordi, Bauer, Philippe R, van de Louw, Andry, Lemiale, Virginie et al.
DOI: 10.1016/j.transproceed.2020.02.170

Aminoglycosides in Immunocompromised Critically Ill Patients with Bacterial Pneumonia and Septic Shock: A Post-Hoc Analysis of a Prospective Multicenter Multinational Cohort.

PMID: 32496415
Journal: SHOCK
Year: 2020
Reference: Shock. 2020 Dec;54(6):731-737. doi: 10.1097/SHK.0000000000001553.
Impact factor: 2.96
Publication type: Paper in international publication
Authors: Rene, Lopez, Rello, Jordi, Silvio, Taccone Fabio, Salem, Omar Ben Hadj, Bauer, Philippe R, Seguin, Amelie, van de Louw, Andry, Metaxa, Victoria, Klouche, Kada, Ignacio, Martin Loeches et al.
DOI: 10.1097/SHK.0000000000001553

The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence?

PMID: 30680576
Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Year: 2019
Reference: Eur J Clin Microbiol Infect Dis. 2019 Apr;38(4):637-647. doi: 10.1007/s10096-019-03486-2. Epub 2019 Jan 24.
Impact factor: 2.591
Publication type: Review in national publication
Authors: Koulenti, Despoina, Parisella, Francesca Romana, Xu, Elena, Lipman, Jeffrey, Rello, Jordi et al.
DOI: 10.1007/s10096-019-03486-2

Postmortem microbiology sampling following death in hospital: an ESGFOR task force consensus statement.

PMID: 30661015
Journal: JOURNAL OF CLINICAL PATHOLOGY
Year: 2019
Reference: J Clin Pathol. 2019 May;72(5):329-336. doi: 10.1136/jclinpath-2018-205365. Epub 2019 Jan 19.
Impact factor: 2.346
Publication type: Paper in international publication
Authors: Burton, Julian L, Saegeman, Veroniek, Arribi, Ana, Andreoletti, Laurent, Cohen, Marta C, Fernandez-Rodriguez, Amparo, Rello, Jordi et al.
DOI: 10.1136/jclinpath-2018-205365

Corrigendum Corrigendum to 'Assessing prediction accuracy for outcomes of ventilator-associated events and infections in critically ill children: a prospective cohort study', [Clinical Microbiology and Infection, Volume 24, Issue 7 (July 2018) Pages 732-737].

PMID: 30217762
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2019
Reference: Clin Microbiol Infect. 2019 Jan;25(1):125. doi: 10.1016/j.cmi.2018.08.019. Epub 2018 Sep 12.
Impact factor: 6.425
Publication type: Letter or abstract
Authors: Campins, M, Lagunes, L, Balcells, J, Rello, J, Pujol, M, Pena-Lopez, Y et al.
DOI: 10.1016/j.cmi.2018.08.019

Evolution over a 15-year period of clinical characteristics and outcomes of critically ill patients with community-acquired bacteremia.

PMID: 23222266
Journal: CRITICAL CARE MEDICINE
Year: 2013
Reference: Crit Care Med. 2013 Jan;41(1):76-83. doi: 10.1097/CCM.0b013e3182676698.
Impact factor: 6.124
Publication type: Paper in international publication
Authors: Marti, G, Valles, Jordi, Palomar, Mercedes, Alvarez-Lerma, Francisco, Rello, Jordi, Blanco, Armando, Garnacho-Montero, Jose, Martin-Loeches, Ignacio, Llata, L, Lopez, M et al.
DOI: 10.1097/CCM.0b013e3182676698

The role of mannose-binding lectin on pneumococcal infection.

PMID: 22523362
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2013
Reference: Eur Respir J. 2013 Jan;41(1):131-9. doi: 10.1183/09031936.00174111. Epub 2012 Apr 20.
Impact factor: 6.355
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1183/09031936.00174111

Impact of obesity in patients infected with 2009 influenza A(H1N1)..

PMID: 20688928
Journal: CHEST
Year: 2011
Reference: Chest. 2011 Feb;139(2):382-6. Epub 2010 Aug 5.
Impact factor: 6.519
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1378/chest.10-1160

Management of community-acquired pneumonia in adults.

PMID: 20693379
Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Year: 2011
Reference: Am J Respir Crit Care Med. 2011 Jan 15;183(2):157-64. Epub 2010 Aug 6.
Impact factor: 10.191
Publication type: Review in international publication
Authors: Wunderink, Richard G, Rello, Jordi, Waterer, Grant W et al.
DOI: 10.1164/rccm.201002-0272CI

[Southern European Intensive Care Nurses' Knowledge of Evidence-Based Guidelines for Preventing Ventilator-Associated Pneumonia.]

PMID: 21122950
Journal: Medicina Intensiva
Year: 2011
Reference: Med Intensiva. 2011 January - February;35(1):6-12. Epub 2010 Nov 30.
Impact factor: 1.496
Publication type: Paper in national publication
Authors: , , , , , , , , , et al.
DOI: 10.1016/j.medin.2010.07.012

Acute kidney injury in critical ill patients affected by influenza A (H1N1) v infection.

PMID: 21342489
Journal: CRITICAL CARE
Year: 2011
Reference: Crit Care. 2011 Feb 22;15(1):R66.
Impact factor: 4.595
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1186/cc10046

Blog

News

A study, in which Vall d'Hebron has participated, has analysed all the interventions of this type carried out between 2006 and 2020.

The work of the multinational team, which has reviewed the records of more than one million patients who have received a new organ, has found significant differences between women and men

The scientific review reports that changes in the respiratory system flora due to pollution increase the risk of suffering a hospital infection caused by multidrug-resistant organisms.