About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
CRIPS is a research group focusing on severe acute respiratory infections and sepsis.
The objective is to develop projects on clinical and translational research in hospital-acquired pneumonia, community-acquired pneumonia, and severe viral respiratory infections, such as influenza and COVID-19. CRIPS also develop epidemiological studies focused on risk and prognostic factors for multi-resistant pathogens, validation of ventilator-associated events in ventilated adult and pediatric patients, incorporating artificial intelligence techniques. It also highlights evidence-based medicine (EBM) research, evaluating therapies and prevention strategies and participating in the formulation of clinical practice guidelines, as part of CIBERES and the European Society for Clinical Microbiology and Infections. The EBM research focuses on knowledge translation to get research findings to the point of decision making, providing health-related recommendations, focusing on clinical research and relevance of care.
CRIPS collaborate on a Local (UIC, IDIAP), National (CIBERES), and International level (CHU Nimes, Uolo University, ISARIC and Pneumo-Inspire Networks).
PMID: 35221837 Journal: EXCLI Journal Year: 2022 Reference: EXCLI J. 2022 Jan 6;21:93-103. doi: 10.17179/excli2021-4439. eCollection 2022. Impact factor: 4.068 Publication type: Paper in international publication Authors: Lefrant, Jean Yves, Zajkowska, Joanna, Rello, Jordi, Kazi, Momin, Taghrir, Mohammad Hossein, Blot, Stijn, Leib, Stephen, Hosseinpour, Parisa, Hosseinpour, Hamidreza, Erfani, Amirhossein et al. DOI: 10.17179/excli2021-4439
PMID: 35203878 Journal: Antibiotics-Basel Year: 2022 Reference: Antibiotics (Basel). 2022 Feb 19;11(2). pii: antibiotics11020275. doi: 10.3390/antibiotics11020275. Impact factor: 4.639 Publication type: Review in international publication Authors: Tejada, Sofia, Forero, Carlos G, Gallego, Miguel, Soriano, Joan B, Cardinal-Fernandez, Pablo A, Ehrmann, Stephan, Rello, Jordi, Ramirez-Estrada, Sergio et al. DOI: 10.3390/antibiotics11020275
PMID: 34807486 Journal: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY Year: 2022 Reference: J Eur Acad Dermatol Venereol. 2022 Mar;36(3):e180-e182. doi: 10.1111/jdv.17828. Epub 2021 Dec 1. Impact factor: 6.166 Publication type: Letter or abstract Authors: Tammaro, A, Karim, D, Adebanjo, G A R, Parisella, F R, Chello, C, Salih, A F, Rello, J et al. DOI: 10.1111/jdv.17828
PMID: 34793762 Journal: JOURNAL OF INFECTION Year: 2022 Reference: J Infect. 2022 Feb;84(2):119-130. doi: 10.1016/j.jinf.2021.11.007. Epub 2021 Nov 15. Impact factor: 6.072 Publication type: Review in international publication Authors: Scardina, Giuditta, Casigliani, Virginia, Petri, Davide, Porretta, Andrea, Moi, Marco, Lucenteforte, Ersilia, Rello, Jordi, Lopalco, Pierluigi, Baggiani, Angelo, Privitera, Gaetano Pierpaolo et al. DOI: 10.1016/j.jinf.2021.11.007
PMID: 33090711 Journal: FEBS Journal Year: 2021 Reference: FEBS J. 2021 Apr;288(7):2184-2202. doi: 10.1111/febs.15588. Epub 2020 Nov 3. Impact factor: 5.542 Publication type: Paper in international publication Authors: Abad, Etna, Civit, Laia, Potesil, David, Zdrahal, Zbynek, Lyakhovich, Alex et al. DOI: 10.1111/febs.15588
PMID: 33734040 Journal: JOURNAL OF CHEMOTHERAPY Year: 2021 Reference: J Chemother. 2021 Sep;33(5):302-318. doi: 10.1080/1120009X.2020.1863696. Epub 2021 Mar 18. Impact factor: 1.714 Publication type: Paper in international publication Authors: Ceviker, Sevil Alkan, Erdem, Hakan, Hargreaves, Sally, Ankarali, Handan, Caskurlu, Hulya, Aslan, Selda, Dar, Razi Even, Abdalla, Esam, Monzon-Camps, Helena, Baljic, Rusmir et al. DOI: 10.1080/1120009X.2020.1863696
PMID: 33712406 Journal: ANALES DE PEDIATRIA Year: 2021 Reference: An Pediatr (Engl Ed). 2021 Mar 9. pii: S1695-4033(20)30498-7. doi: 10.1016/j.anpedi.2020.11.012. Impact factor: 1.5 Publication type: Letter whit IF Authors: Brunet-Garcia, Laia, Roses-Noguer, Ferran, Betrian, Pedro, Balcells, Joan, Gran, Ferran et al. DOI: 10.1016/j.anpedi.2020.11.012
PMID: 33692181 Journal: BMJ Open Year: 2021 Reference: BMJ Open. 2021 Mar 10;11(3):e043887. doi: 10.1136/bmjopen-2020-043887. Impact factor: 2.692 Publication type: Paper in international publication Authors: Palmieri, Carlo, Munblit, Daniel, Holter, Jan Cato, Kildal, Anders Benjamin, Reyes, Luis Felipe, Russell, Clark D, Ho, Antonia, Turtle, Lance, Drake, Thomas M, Beltrame, Anna et al. DOI: 10.1136/bmjopen-2020-043887
PMID: 32446623 Journal: CHEST Year: 2020 Reference: Chest. 2020 Sep;158(3):929-938. doi: 10.1016/j.chest.2020.03.087. Epub 2020 May 22. Impact factor: 8.308 Publication type: Review in international publication Authors: Zasowski, Evan J, Bassetti, Matteo, Blasi, Francesco, Goossens, Herman, Rello, Jordi, Sotgiu, Giovanni, Tavoschi, Lara, Arber, Mick R, McCool, Rachael, Patterson, Jacoby V et al. DOI: 10.1016/j.chest.2020.03.087
PMID: 32379379 Journal: International Wound Journal Year: 2020 Reference: Int Wound J. 2020 Oct;17(5):1520-1522. doi: 10.1111/iwj.13397. Epub 2020 May 7. Impact factor: 2.825 Publication type: Letter or abstract Authors: Tammaro, Antonella, Sernicola, Alvise, Chello, Camilla, Cerbelli, Edoardo, Adebanjo, Ganiyat Adenike Ralitsa, Parisella, Francesca Romana, Pezzuto, Aldo, Luzi, Fabiola, De Marco, Gabriella, Rello, Jordi et al. DOI: 10.1111/iwj.13397
PMID: 32347523 Journal: ADVANCES IN THERAPY Year: 2020 Reference: Adv Ther. 2020 Jun;37(6):2646-2666. doi: 10.1007/s12325-020-01347-5. Epub 2020 Apr 28. Impact factor: 3.871 Publication type: Review in international publication Authors: Tejada, Sofia, Campogiani, Laura, Sole-Lleonart, Candela, Rello, Jordi et al. DOI: 10.1007/s12325-020-01347-5
PMID: 32341111 Journal: EUROPEAN RESPIRATORY JOURNAL Year: 2020 Reference: Eur Respir J. 2020 May 21;55(5). pii: 13993003.01028-2020. doi: 10.1183/13993003.01028-2020. Print 2020 May. Impact factor: 12.339 Publication type: Paper in international publication Authors: Rello, Jordi, Storti, Enrico, Belliato, Mirko, Serrano, Ricardo et al. DOI: 10.1183/13993003.01028-2020
PMID: 31085298 Journal: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS Year: 2019 Reference: Int J Antimicrob Agents. 2019 Jul;54(1):16-22. doi: 10.1016/j.ijantimicag.2019.05.012. Epub 2019 May 11. Impact factor: 4.615 Publication type: Editorail in international publication Authors: Masterton, Robert G, Bassetti, Matteo, Chastre, Jean, MacDonald, Alan G, Rello, Jordi, Seaton, R Andrew, Welte, Tobias, West, Peter, Wilcox, Mark H et al. DOI: 10.1016/j.ijantimicag.2019.05.012
PMID: 30207133 Journal: Minerva Anestesiologica Year: 2019 Reference: Minerva Anestesiol. 2019 Apr;85(4):366-375. doi: 10.23736/S0375-9393.18.12687-3. Epub 2018 Sep 10. Impact factor: 2.84 Publication type: Paper in international publication Authors: Rodriguez-Gutierrez, Juan F, Estella Garcia, Angel, Fernandez-Ruiz, Laura, Gonzalez-Garcia, Maria A, Rello, Jordi, Austria, Rafael Bohollo de, Valenzuela-Mendez, Blanca, Valenzuela-Sanchez, Francisco et al. DOI: 10.23736/S0375-9393.18.12687-3
PMID: 30922608 Journal: Medicina Intensiva Year: 2019 Reference: Med Intensiva. 2019 Nov;43(8):480-488. doi: 10.1016/j.medin.2019.01.009. Epub 2019 Mar 25. Impact factor: 1.982 Publication type: Paper in national publication Authors: Roche, Alejandra Garcia, Lagares, Candido Diaz, Elez, Elena, Roca, Ricard Ferrer et al. DOI: 10.1016/j.medin.2019.01.009
PMID: 30900056 Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES Year: 2019 Reference: Eur J Clin Microbiol Infect Dis. 2019 Jul;38(7):1235-1240. doi: 10.1007/s10096-019-03530-1. Epub 2019 Mar 21. Impact factor: 2.591 Publication type: Paper in international publication Authors: Alp, Emine, Rello, Jordi, Kalwaje Eshwara, Vandana, Conway-Morris, Andrew, Lagunes, Leonel, Alves, Joana, Mer, Mervyn, Zhang, Zhongheng et al. DOI: 10.1007/s10096-019-03530-1
PMID: 29318460 Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES Year: 2018 Reference: Eur J Clin Microbiol Infect Dis. 2018 Apr;37(4):785-794. doi: 10.1007/s10096-017-3175-5. Epub 2018 Jan 9. Impact factor: 2.537 Publication type: Paper in international publication Authors: Alves, Joana, Alp, Emine, Koulenti, Despoina, Zhang, Zhongheng, Ehrmann, Stephan, Blot, Stijn, Bassetti, Matteo, Conway-Morris, Andrew, Reina, Rosa, Teran, Enrique et al. DOI: 10.1007/s10096-017-3175-5
PMID: 28600902 Journal: ALLERGY Year: 2018 Reference: Allergy. 2018 Jan;73(1):77-92. doi: 10.1111/all.13218. Epub 2017 Aug 24. Impact factor: 6.048 Publication type: Paper in international publication Authors: De Feo, G, Bousquet, J, Agache, I, Aliberti, M R, Angles, R, Annesi-Maesano, I, Anto, J M, Arnavielhe, S, Asayag, E, Bacci, E et al. DOI: 10.1111/all.13218
PMID: 29038277 Journal: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Year: 2018 Reference: Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: AAC.01323-17. doi: 10.1128/AAC.01323-17. Print 2018 Jan. Impact factor: 4.255 Publication type: Paper in international publication Authors: Walsh, Thomas J, Dorizas, Krisztina, Alnuaimat, Hassan, Morgan, Brooks Edward, Rello, Jordi, Mazo Torre, Cristopher Alan, Jones, Ronald N, Flamm, Robert K, Woosley, Leah, Ambrose, Paul G et al. DOI: 10.1128/AAC.01323-17
PMID: 28248714 Journal: ANESTHESIOLOGY Year: 2017 Reference: Anesthesiology. 2017 May;126(5):890-908. doi: 10.1097/ALN.0000000000001570. Impact factor: 5.66 Publication type: Paper in international publication Authors: Dhanani, Jayesh, Sole-Lleonart, Candela, Rouby, Jean-Jacques, Blot, Stijn, Poulakou, Garyfallia, Chastre, Jean, Palmer, Lucy B, Bassetti, Matteo, Luyt, Charles-Edouard, Pereira, Jose M et al. DOI: 10.1097/ALN.0000000000001570
PMID: 28159015 Journal: CRITICAL CARE Year: 2017 Reference: Crit Care. 2017 Feb 4;21(1):22. doi: 10.1186/s13054-017-1601-9. Impact factor: 5.358 Publication type: Paper in international publication Authors: Rello, Jordi, Krenn, Claus-Georg, Locker, Gottfried, Burgmann, Heinz, Welte, Tobias, Klingler, Anton, Hochreiter, Romana, Westritschnig, Kerstin, Joannidis, Michael, Lyons, Arthur et al. DOI: 10.1186/s13054-017-1601-9
PMID: 28094139 Journal: Lancet Respiratory Medicine Year: 2017 Reference: Lancet Respir Med. 2017 Feb;5(2):91-92. doi: 10.1016/S2213-2600(17)30005-X. Epub 2017 Jan 14. Impact factor: 19.287 Publication type: Review in international publication Authors: Rello, Jordi et al. DOI: 10.1016/S2213-2600(17)30005-X
PMID: 28093651 Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES Year: 2017 Reference: Eur J Clin Microbiol Infect Dis. 2017 Jul;36(7):1097-1104. doi: 10.1007/s10096-016-2894-3. Epub 2017 Jan 16. Impact factor: 2.727 Publication type: Paper in international publication Authors: Borgatta, B, Lagunes, L, Imbiscuso, A T, Larrosa, M N, Lujan, M, Rello, J et al. DOI: 10.1007/s10096-016-2894-3
PMID: 26957647 Journal: Respiratory Care Year: 2016 Reference: Respir Care. 2016 Aug;61(8):1008-14. doi: 10.4187/respcare.04519. Epub 2016 Mar 8. Impact factor: 1.922 Publication type: Paper in international publication Authors: Sole-Lleonart, Candela, Rouby, Jean-Jacques, Chastre, Jean, Poulakou, Garyfallia, Palmer, Lucy B, Blot, Stijn, Felton, Tim, Bassetti, Matteo, Luyt, Charles-Eduard, Pereira, Joao Manuel et al. DOI: 10.4187/respcare.04519
PMID: 26936615 Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES Year: 2016 Reference: Eur J Clin Microbiol Infect Dis. 2016 Jun;35(6):893-7. doi: 10.1007/s10096-016-2611-2. Epub 2016 Mar 2. Impact factor: 2.857 Publication type: Paper in international publication Authors: Valenzuela-Sanchez, F, Valenzuela-Mendez, B, Rodriguez-Gutierrez, J F, Rello, J et al. DOI: 10.1007/s10096-016-2611-2
PMID: 26789703 Journal: Expert Review of Vaccines Year: 2016 Reference: Expert Rev Respir Med. 2016;10(3):297-316. doi: 10.1586/17476348.2016.1144477. Epub 2016 Feb 9. Impact factor: 4.222 Publication type: Paper in international publication Authors: Perez, Antonio, Rello, Jordi et al. DOI: 10.1586/17476348.2016.1144477
PMID: 26727202 Journal: PLoS One Year: 2016 Reference: PLoS One. 2016 Jan 4;11(1):e0145929. doi: 10.1371/journal.pone.0145929. eCollection 2016. Impact factor: 3.057 Publication type: Paper in international publication Authors: Bello, Salvador, Martin-Villasclaras, Juan, Borderias, Luis, Rajas, Olga, Capelastegui, Alberto, Zalacain, Rafael, Mendez, Raul, Reyes, Soledad, Torres, Antoni, Menendez, Rosario et al. DOI: 10.1371/journal.pone.0145929
PMID: 24633125 Journal: CRIT CARE MED Year: 2014 Reference: Crit Care Med. 2014 Apr;42(4):e314-5. doi: 10.1097/CCM.0000000000000179. Impact factor: 6.147 Publication type: Letter whit IF Authors: Blot, Stijn, Koulenti, Despoina, Rello, Jordi et al. DOI: 10.1097/CCM.0000000000000179
PMID: 24606193 Journal: LIVER INT Year: 2014 Reference: Liver Int. 2014 Nov;34(10):1496-503. doi: 10.1111/liv.12520. Epub 2014 Mar 26. Impact factor: 4.447 Publication type: Paper in international publication Authors: Gustot, Thierry, Felleiter, Peter, Pickkers, Peter, Sakr, Yasser, Rello, Jordi, Velissaris, Dimitrios, Pierrakos, Charalampos, Taccone, Fabio S, Sevcik, Pavel, Moreno, Christophe et al. DOI: 10.1111/liv.12520
PMID: 24158167 Journal: CRIT CARE MED Year: 2014 Reference: Crit Care Med. 2014 Mar;42(3):601-9. doi: 10.1097/01.ccm.0000435665.07446.50. Impact factor: 6.147 Publication type: Paper in international publication Authors: Blot, Stijn, Koulenti, Despoina, Dimopoulos, George, Martin, Claude, Komnos, Apostolos, Krueger, Wolfgang A, Spina, Giuseppe, Armaganidis, Apostolos, Rello, Jordi et al. DOI: 10.1097/01.ccm.0000435665.07446.50
PMID: 24518214 Journal: MINERVA ANESTESIOL Year: 2014 Reference: Minerva Anestesiol. 2014 Nov;80(11):1234-45. Epub 2014 Feb 11. Impact factor: 2.272 Publication type: Paper in national publication Authors: Leal, S, Sacanell, J, Riera, J, Masclans, J R, Rello, J et al. DOI:
PMID: 22781339 Journal: Respiratory Care Year: 2013 Reference: Respir Care. 2013 Feb;58(2):273-8. doi: 10.4187/respcare.01911. Impact factor: 2.03 Publication type: Paper in international publication Authors: Condomines, Jordi Rello, Pena, Miriam Gonzalez, Massana, Enric Figuerola, Gutierrez, Pilar Hernandez et al. DOI: 10.4187/respcare.01911
PMID: 23044282 Journal: Medicina Intensiva Year: 2013 Reference: Med Intensiva. 2013 May;37(4):299-300. doi: 10.1016/j.medin.2012.08.005. Epub 2012 Oct 6. Impact factor: 1.323 Publication type: Letter whit IF Authors: Caralt-Ramisa, B, Fernandez-Codina, A, Bravo, C, Rello, J, Farre, M, Masclans, J R et al. DOI: 10.1016/j.medin.2012.08.005
PMID: 23260267 Journal: Medicina Intensiva Year: 2013 Reference: Med Intensiva. 2013 Apr;37(3):201-205. doi: 10.1016/j.medin.2012.10.003. Epub 2012 Dec 20. Impact factor: 1.323 Publication type: Paper in national publication Authors: Sacanell, J, Rey, T, Lopez, E, Vicente, R, Ballesteros, M A, Iranzo, R, Robles, J C, Restrepo, M I, Rello, J et al. DOI: 10.1016/j.medin.2012.10.003
PMID: 22583156 Journal: CLINICAL MICROBIOLOGY AND INFECTION Year: 2013 Reference: Clin Microbiol Infect. 2013 Apr;19(4):385-91. doi: 10.1111/j.1469-0691.2012.03895.x. Epub 2012 May 14. Impact factor: 4.578 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1111/j.1469-0691.2012.03895.x
PMID: 22402103 Journal: ANALES DE PEDIATRIA Year: 2012 Reference: An Pediatr (Barc). 2012 Mar;76(3):117-9. Impact factor: 0.77 Publication type: Editorial in national publication Authors: Sanchez de Toledo, J, Balcells, J et al. DOI: 10.1016/j.anpedi.2012.01.026
PMID: 21828033 Journal: EUROPEAN RESPIRATORY JOURNAL Year: 2012 Reference: Eur Respir J. 2012 Jan;39(1):156-62. Epub 2011 Aug 4. Impact factor: 5.895 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1183/09031936.00188710
PMID: 22366995 Journal: CURRENT OPINION IN PULMONARY MEDICINE Year: 2012 Reference: Curr Opin Pulm Med. 2012 May;18(3):187-93. doi: 10.1097/MCP.0b013e328351f974. Impact factor: 3.075 Publication type: Review in international publication Authors: , et al. DOI: 10.1097/MCP.0b013e328351f974
PMID: 22240033 Journal: JOURNAL OF INFECTION Year: 2012 Reference: J Infect. 2012 Mar;64(3):311-8. doi: 10.1016/j.jinf.2011.12.010. Epub 2012 Jan 2. Impact factor: 4.126 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1016/j.jinf.2011.12.010
PMID: 21385717 Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Year: 2011 Reference: J Antimicrob Chemother. 2011 May;66(5):1140-9. Epub 2011 Jan 7. Impact factor: 4.659 Publication type: Paper in international publication Authors: García-López, Fernando, Rodriguez, Alejandro, Emili Diaz, Martin Loeches, Ignacio, Sandiumenge, Alberto, Canadell, Laura, Diaz, Juan J., Figueira, Juan C., Marques, Asuncion, Alvarez-Lerma, Francisco et al. DOI: 10.1093/jac/dkq511
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PMID: 20930007 Journal: CHEST Year: 2011 Reference: Chest. 2011 Mar;139(3):555-62. Epub 2010 Oct 7. Impact factor: 6.519 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1378/chest.10-1396
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PMID: 19811966 Journal: Medicina Intensiva Year: 2009 Reference: Med Intensiva. 2009 Aug-Sep;33(6):265-6. Impact factor: Publication type: Letter or abstract Authors: Rodriguez, Alejandro, Lisboa, Thiago, Diaz, Emili, Rello, Jordi, Leon, Cristobal et al. DOI: 10.1016/S0210-5691(09)72192-8
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PMID: 19335051 Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS Year: 2009 Reference: Rev Esp Enferm Dig. 2009 Feb;101(2):139-41, 141-3. Impact factor: 1.263 Publication type: Paper in national publication Authors: Armengol-Miro, J R, Azpiroz, F, Accarino, A, Planas, M, Dot, J, Charco, R, Malagelada, C, Llopart, L, Bueno, J, Bilbao, I et al. DOI:
A study, in which Vall d'Hebron has participated, has analysed all the interventions of this type carried out between 2006 and 2020.
The work of the multinational team, which has reviewed the records of more than one million patients who have received a new organ, has found significant differences between women and men
The scientific review reports that changes in the respiratory system flora due to pollution increase the risk of suffering a hospital infection caused by multidrug-resistant organisms.
