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Diabetes and Metabolism

The Diabetes and Metabolism Research Group is search is lead by Dr. Rafael Simó (Hirsch index:54), Head of the Endocrinology Department, Professor of Medicine & Endocrinology at UAB and current President of the European Association for the Study of Diabetes-Eye Complications. The group consists of 7 senior clinical investigators, 4 basic post-doctoral researchers, 4 pre-doc researchers, 3 laboratory technicians and one coordinator of clinical assays.  

The group belongs to “CIBER” of Diabetes and Associated Metabolic Diseases (CIBERDEM. ISCIII) and has been recognized as consolidated group by the Generalitat de Catalunya (AQU/AGAUR).

Since 2014 this group has been qualified as outstanding in the evaluations performed by the ANEP, CIBERDEM and the external Scientific Advisory Board of VHIR. 

The main lines of research are:

  • Complications of diabetes (in particular diabetic retinopathy)
  • Obesity and its co-morbidities
  • Type 2 diabetes and cognitive impairment
  • Thyroid diseases
  • Hospital Nutrition. 

Team

Ana Alvarez Guaita

Ana Alvarez Guaita

Postdoctoral researcher
Diabetes and Metabolism
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Andreea Ciudin Mihai

Andreea Ciudin Mihai

Main researcher
Diabetes and Metabolism
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Angel Michael Ortiz Zuñiga

Angel Michael Ortiz Zuñiga

Postdoctoral researcher
Diabetes and Metabolism
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Anna Deàs Just

Anna Deàs Just

Predoctoral researcher
Diabetes and Metabolism
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Betina Biagetti Biagetti

Betina Biagetti Biagetti

Diabetes and Metabolism
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Carles Zafon Llopis

Carles Zafon Llopis

Diabetes and Metabolism
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Ana Alvarez Guaita

Ana Alvarez Guaita

Postdoctoral researcher
Diabetes and Metabolism
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Andreea Ciudin Mihai

Andreea Ciudin Mihai

Main researcher
Diabetes and Metabolism
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Angel Michael Ortiz Zuñiga

Angel Michael Ortiz Zuñiga

Postdoctoral researcher
Diabetes and Metabolism
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Anna Deàs Just

Anna Deàs Just

Predoctoral researcher
Diabetes and Metabolism
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Betina Biagetti Biagetti

Betina Biagetti Biagetti

Diabetes and Metabolism
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Carles Zafon Llopis

Carles Zafon Llopis

Diabetes and Metabolism
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Projects

BIO-STREAM: Multi-Pillar Framework for children Anti-Obesity Behavior building on an EU biobank, Micro Moments and Mobile Recommendation Systems

IP: Andreea Ciudin Mihai
Collaborators: Marta Comas Martínez
Funding agency: EUROPEAN COMMISSION
Funding: 317500
Reference: BIO-STREAM_HE-HLTH-STAYHLTH2022
Duration: 01/05/2023 - 30/04/2027

Utilidad de la inteligencia artificial en el análisis de imágenes de retina para identificar los pacientes con mayor riesgo de progresión de la retinopatía diabética en el mundo real.

IP: Olga Simó Servat
Collaborators: Rafael Simó Canonge, Cristina Hernández Pascual
Funding agency: Sociedad Española de Diabetes
Funding: 20000
Reference: SED/PJ.JOVES.INVEST/2022/SIMO
Duration: 29/05/2023 - 28/05/2024

Utilitat de la inteligència artificial en l’anàlisi d’imatges de retina per identificar els pacients amb major risc de progressió de la retinopatia diabètica en el món real

IP: Olga Simó Servat
Collaborators: -
Funding agency: Associació Catalana de Diabetis
Funding: 10000
Reference: ACD/PROJECTES22/SIMO
Duration: 09/03/2023 - 08/03/2025

Beca VHIR PhD

IP: Josep A Villena Delgado
Collaborators: Sira Rodrigo Bosch, Laia Perez Lasarte, Rafael Simó Canonge, Laura Hidalgo Corbacho, Miriam Izquierdo Sans
Funding agency: Fundació Institut de Recerca HUVH
Funding: 69188.74
Reference: VPHD/LAURA_H
Duration: 01/04/2023 - 31/03/2026

Publications

Blocking hemopexin with specific antibodies: a new strategy for treating diabetic retinopathy.

PMID: 37722135
Journal: DIABETES
Year: 2023
Reference: Diabetes. 2023 Sep 18:db230027. doi: 10.2337/db23-0027.
Impact factor:
Publication type: Paper in international publication
Authors: Bogdanov, Patricia; Duarri, Anna; Garcia-Arumi, Jose; Garcia-Arumi, Jose; Hernandez, Cristina; Hernandez, Cristina; Huerta, Jordi; Isla-Magrane, Helena; Ramos, Hugo; Sabater, David et al.
DOI: 10.2337/db23-0027

Efficacy and safety of temozolomide in the treatment of aggressive pituitary neuroendocrine tumours in Spain.

PMID: 37720528
Journal: Frontiers in Endocrinology
Year: 2023
Reference: Front Endocrinol (Lausanne). 2023 Aug 31;14:1204206. doi: 10.3389/fendo.2023.1204206. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Araujo-Castro, Marta; Biagetti, Betina; Biagetti, Betina; Camara, Rosa; Fajardo, Carmen; Garcia-Centeno, Rogelio; Guerrero-Perez, Fernando; Hanzu, Felicia; Iglesias, Pedro; Lamas, Cristina et al.
DOI: 10.3389/fendo.2023.1204206

Switching to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) plus darunavir/cobicistat in heavily antiretroviral-experienced, virologically suppressed HIV-infected adults receiving complex regimens.

PMID: 37725999
Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Year: 2023
Reference: J Antimicrob Chemother. 2023 Sep 19:dkad285. doi: 10.1093/jac/dkad285.
Impact factor:
Publication type: Paper in international publication
Authors: Ardila, Fernando; Bernal, Enrique; Casadella, Maria; Curran, Adria; Curran, Adria; Echeverria, Patricia; Estrada, Vicente; Fanciulli, Chiara; Gutierrez, Angela; Hernandez, Cristina et al.
DOI: 10.1093/jac/dkad285

Structural and metabolic retinal changes associated with mild cognitive impairment in type 2 diabetes.

PMID: 37725903
Journal: DIABETES
Year: 2023
Reference: Diabetes. 2023 Sep 19:db230025. doi: 10.2337/db23-0025.
Impact factor:
Publication type: Paper in international publication
Authors: Biessels, Geert Jan; Cheung, Carol Y; Exalto, Lieza; Grauslund, Jakob; Lois, Noemi; Pedersen, Frederik N; Peto, Tunde; Pouwer, Frans; Simo, Rafael; Stokholm, Lonny et al.
DOI: 10.2337/db23-0025

Neuronal Dysfunction Is Linked to the Famine-Associated Risk of Proliferative Retinopathy in Patients With Type 2 Diabetes.

PMID: 35600617
Journal: Frontiers in Neuroscience
Year: 2022
Reference: Front Neurosci. 2022 May 5;16:858049. doi: 10.3389/fnins.2022.858049. eCollection 2022.
Impact factor: 4.677
Publication type: Paper in international publication
Authors: Khalangot, Mykola D, Hernandez, Cristina, Nilsson, Peter M, Simo, Rafael, Artner, Isabella, Lyssenko, Valeriya, Chan, Juliana, Vaag, Allan, Kravchenko, Victor, Fedotkina, Olena et al.
DOI: 10.3389/fnins.2022.858049

ERM Complex, a Therapeutic Target for Vascular Leakage Induced by Diabetes.

PMID: 34042029
Journal: CURRENT MEDICINAL CHEMISTRY
Year: 2022
Reference: Curr Med Chem. 2022;29(12):2189-2199. doi: 10.2174/0929867328666210526114417.
Impact factor: 4.53
Publication type: Paper in international publication
Authors: Simo-Servat, Olga, Ramos, Hugo, Bogdanov, Patricia, Garcia-Ramirez, Marta, Huerta, Jordi, Hernandez, Cristina, Simo, Rafael et al.
DOI: 10.2174/0929867328666210526114417

Soluble Angiotensin-Converting Enzyme 2 as a Prognostic Biomarker for Disease Progression in Patients Infected with SARS-CoV-2.

PMID: 35453934
Journal: Diagnostics
Year: 2022
Reference: Diagnostics (Basel). 2022 Apr 1;12(4). pii: diagnostics12040886. doi: 10.3390/diagnostics12040886.
Impact factor: 3.706
Publication type: Paper in international publication
Authors: Gabriel-Medina, Pablo, Diaz-Troyano, Noelia, Barquin-DelPino, Raquel, Castillo-Ribelles, Laura, Esteban, Angels, Hernandez-Gonzalez, Manuel, Ferrer-Costa, Roser, Pumarola, Tomas, Rodriguez-Frias, Francisco, Klammer, Martin et al.
DOI: 10.3390/diagnostics12040886

LYMPHOCYTIC THYROIDITIS TRANSCRIPTOMIC PROFILES SUPPORT THE ROLE OF CHECKPOINT PATHWAYS AND B CELLS IN PATHOGENESIS.

PMID: 35403441
Journal: THYROID
Year: 2022
Reference: Thyroid. 2022 Jun;32(6):682-693. doi: 10.1089/thy.2021.0694. Epub 2022 May 25.
Impact factor: 6.568
Publication type: Paper in international publication
Authors: Zafon, Carles, Alvarez de la Sierra, Daniel, Marin-Sanchez, Ana, Gomez-Brey, Aroa, Bello, Irene, Caubet, Enric, Moreno-Llorente, Pablo, Petit, Anna, Pujol-Borrell, Ricardo, Gonzalez, Oscar et al.
DOI: 10.1089/thy.2021.0694

The Gaze Fixation Assessed by Microperimetry: A Useful Tool for the Monitoring of the Cognitive Function in Patients with Type 2 Diabetes.

PMID: 34442342
Journal: Journal of Personalized Medicine
Year: 2021
Reference: J Pers Med. 2021 Jul 22;11(8). pii: jpm11080698. doi: 10.3390/jpm11080698.
Impact factor: 4.945
Publication type: Paper in international publication
Authors: Simo, Rafael, Ciudin, Andreea, Hernandez, Cristina, Castellano-Tejedor, Carmina, Vazquez-de Sebastian, Julia, Rojano-Toimil, Alba, Ortiz-Zuniga, Angel Michael, Simo-Servat, Olga et al.
DOI: 10.3390/jpm11080698

Shrinkage by the third month predicts long-term response of macroprolactinoma after cabergoline.

PMID: 34374649
Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY
Year: 2021
Reference: Eur J Endocrinol. 2021 Sep 1;185(4):587-595. doi: 10.1530/EJE-21-0561.
Impact factor: 6.664
Publication type: Paper in international publication
Authors: Biagetti, Betina, Sarria-Estrada, Silvana, Ng-Wong, Yiken Karelys, Martinez-Saez, Elena, Cordero Asanza, Esteban, Casteras, Anna, Hernandez, Irene, Giralt-Arnaiz, Marina, Simo, Rafael et al.
DOI: 10.1530/EJE-21-0561

Cardiac-Specific Overexpression of ERRgamma in Mice Induces Severe Heart Dysfunction and Early Lethality.

PMID: 34360813
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2021
Reference: Int J Mol Sci. 2021 Jul 28;22(15). pii: ijms22158047. doi: 10.3390/ijms22158047.
Impact factor: 5.924
Publication type: Paper in international publication
Authors: Lasheras, Jaime, Pardo, Rosario, Velilla, Marc, Poncelas, Marcos, Salvatella, Nuria, Simo, Rafael, Ruiz-Meana, Marisol, Zamora, Monica, Villena, Josep A et al.
DOI: 10.3390/ijms22158047

Evaluation of Resting Energy Expenditure in Subjects with Severe Obesity and Its Evolution After Bariatric Surgery.

PMID: 34345955
Journal: OBESITY SURGERY
Year: 2021
Reference: Obes Surg. 2021 Oct;31(10):4347-4355. doi: 10.1007/s11695-021-05578-5. Epub 2021 Aug 3.
Impact factor: 4.129
Publication type: Paper in international publication
Authors: Fidilio, Enzamaria, Comas, Marta, Giribes, Miguel, Cardenas, Guillermo, Vilallonga, Ramon, Palma, Fiorella, Pelaez, Rosa Burgos, Simo, Rafael, Ciudin, Andreea et al.
DOI: 10.1007/s11695-021-05578-5

Hsa-miR-139-5p is a prognostic thyroid cancer marker involved in HNRNPF-mediated alternative splicing.

PMID: 31403184
Journal: INTERNATIONAL JOURNAL OF CANCER
Year: 2020
Reference: Int J Cancer. 2020 Jan 15;146(2):521-530. doi: 10.1002/ijc.32622. Epub 2019 Aug 28.
Impact factor: 5.145
Publication type: Paper in international publication
Authors: Roldan-Romero, J M, Montero-Conde, C, Grana-Castro, O, Martin-Serrano, G, Martinez-Montes, A M, Zarzuela, E, Munoz, J, Torres-Perez, R, Pita, G, Cordero-Barreal, A et al.
DOI: 10.1002/ijc.32622

[Parenteral domiciliary nutrition Program: 32 years of clinical experience].

PMID: 31475838
Journal: Nutricion Hospitalaria
Year: 2019
Reference: Nutr Hosp. 2019 Oct 17;36(5):1011-1018. doi: 10.20960/nh.02461.
Impact factor: 0.759
Publication type: Letter or abstract
Authors: Simo Servat, Andreu, Lopez Urdiales, Rafael, Planas-Vilaseca, Alejandra, Garcia-Sancho de la Jordana, Paula, Fernandez Alvarez, Monica, Leiva Baldosa, Elisabet, Badia Tahull, Maria B, Virgili Casas, Maria Nuria et al.
DOI: 10.20960/nh.02461

SOCS1-Derived Peptide Administered by Eye Drops Prevents Retinal Neuroinflammation and Vascular Leakage in Experimental Diabetes.

PMID: 31344857
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2019
Reference: Int J Mol Sci. 2019 Jul 24;20(15). pii: ijms20153615. doi: 10.3390/ijms20153615.
Impact factor: 4.183
Publication type: Paper in international publication
Authors: Gomez-Guerrero, Carmen, Sampedro, Joel, Sola-Adell, Cristina, Espejo, Carmen, Garcia-Ramirez, Marta, Prieto, Ignacio, Egido, Jesus, Simo, Rafael, Bogdanov, Patricia, Hernandez, Cristina et al.
DOI: 10.3390/ijms20153615

Acromegaly remission, SIADH and pituitary function recovery after macroadenoma apoplexy

PMID: 31310082
Journal: Endocrinology, diabetes & metabolism case repo
Year: 2019
Reference: Endocrinol Diabetes Metab Case Rep. 2019 Jul 15;2019(1). doi: 10.1530/EDM-19-0057.
Impact factor: 0
Publication type: Paper in international publication
Authors: Arikan, F, Sanz-Sapera, E, Sarria-Estrada, S, Biagetti, B et al.
DOI: 10.1530/EDM-19-0057

Prevalence and risk factors for hypoparathyroidism following total thyroidectomy in Spain: a multicentric and nation-wide retrospective analysis.

PMID: 31317524
Journal: ENDOCRINE
Year: 2019
Reference: Endocrine. 2019 Nov;66(2):405-415. doi: 10.1007/s12020-019-02014-8. Epub 2019 Jul 17.
Impact factor: 3.296
Publication type: Paper in international publication
Authors: Diez, Juan J, Anda, Emma, Sastre, Julia, Perez Corral, Begona, Alvarez-Escola, Cristina, Manjon, Laura, Paja, Miguel, Sambo, Marcel, Santiago Fernandez, Piedad, Blanco Carrera, Concepcion et al.
DOI: 10.1007/s12020-019-02014-8

Increased global DNA hypomethylation in distant metastatic and dedifferentiated thyroid cancer.

PMID: 29165662
Journal: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Year: 2018
Reference: J Clin Endocrinol Metab. 2018 Feb 1;103(2):397-406. doi: 10.1210/jc.2017-01613.
Impact factor: 5.789
Publication type: Paper in international publication
Authors: Klein Hesselink, E N, Zafon, Carles, Villalmanzo, Nuria, Iglesias, Carmela, van Hemel, B M, Klein Hesselink, M S, Montero-Conde, Cristina, Buj, Raquel, Mauricio, Didac, Peinado, Miguel A et al.
DOI: 10.1210/jc.2017-01613

Pasireotide in acromegaly by aggressive tumors, description of four clinical cases.. Towards a personalized medicine.

PMID: 29371000
Journal: Endocrinologia, diabetes y nutricion
Year: 2018
Reference: Endocrinol Diabetes Nutr. 2018 Feb;65(2):130-132. doi: 10.1016/j.endinu.2017.12.001. Epub 2018 Jan 20.
Impact factor: 0
Publication type: Paper in national publication
Authors: Biagetti, Betina, Obiols, Gabriel, Martinez Saez, Elena, Cordero, Esteban, Mesa, Jordi et al.
DOI: 10.1016/j.endinu.2017.12.001

Response to oral sucrosomial iron supplementation in patients undergoing bariatric surgery. The BARI-FER study.

PMID: 29233512
Journal: Endocrinologia, diabetes y nutricion
Year: 2018
Reference: Endocrinol Diabetes Nutr. 2018 Jan;65(1):17-20. doi: 10.1016/j.endinu.2017.10.007. Epub 2017 Dec 7.
Impact factor: 0
Publication type: Paper in national publication
Authors: Simo, Rafael, Mesa, Jordi, Hernandez, Cristina, Vilallonga, Ramon, Balibrea, Jose Maria, Simo-Servat, Olga, Ciudin, Andreea et al.
DOI: 10.1016/j.endinu.2017.10.007

Serum Surfactant Protein D as a Biomarker for Measuring Lung Involvement in Obese Type 2 Diabetic Patients.

PMID: 28945872
Journal: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Year: 2017
Reference: J Clin Endocrinol Metab. 2017 Nov 1;102(11):4109-4116. doi: 10.1210/jc.2017-00913.
Impact factor: 5.455
Publication type: Paper in international publication
Authors: Ciudin, Andreea, Gutierrez, Liliana, Hernandez, Cristina, Simo, Rafael, Hernandez, Marta, Seminario, Asuncion, Sanchez, Enric, Munoz, Xavier, Lopez-Cano, Carolina, Lecube, Albert et al.
DOI: 10.1210/jc.2017-00913

Selective sentinel lymph node biopsy in papillary thyroid carcinoma in patients with no preoperative evidence of lymph node metastasis.

PMID: 28895542
Journal: Endocrinologia, diabetes y nutricion
Year: 2017
Reference: Endocrinol Diabetes Nutr. 2017 Oct;64(8):451-455. doi: 10.1016/j.endinu.2017.05.001. Epub 2017 Jun 29.
Impact factor: 0
Publication type: Paper in national publication
Authors: Gonzalez, Oscar, Zafon, Carles, Caubet, Enric, Garcia-Burillo, Amparo, Serres, Xavier, Fort, Jose Manuel, Mesa, Jordi, Castell, Joan, Roca, Isabel, Ramon Y Cajal, Santiago et al.
DOI: 10.1016/j.endinu.2017.05.001

Calcium dobesilate prevents the oxidative stress and inflammation induced by diabetes in the retina of db/db mice.

PMID: 28847447
Journal: JOURNAL OF DIABETES AND ITS COMPLICATIONS
Year: 2017
Reference: J Diabetes Complications. 2017 Oct;31(10):1481-1490. doi: 10.1016/j.jdiacomp.2017.07.009. Epub 2017 Jul 26.
Impact factor: 2.734
Publication type: Paper in international publication
Authors: Bogdanov, Patricia, Sola-Adell, Cristina, Hernandez, Cristina, Garcia-Ramirez, Marta, Sampedro, Joel, Simo-Servat, Olga, Valeri, Marta, Pasquali, Christian, Simo, Rafael et al.
DOI: 10.1016/j.jdiacomp.2017.07.009

Topical administration of DPP-IV inhibitors prevents retinal neurodegeneration in experimental diabetes.

PMID: 28779212
Journal: DIABETOLOGIA
Year: 2017
Reference: Diabetologia. 2017 Nov;60(11):2285-2298. doi: 10.1007/s00125-017-4388-y. Epub 2017 Aug 4.
Impact factor: 6.08
Publication type: Paper in international publication
Authors: Garcia-Ramirez, Marta, Simo, Rafael, Simo-Servat, Olga, Genis, Xavier, Valeri, Marta, Sampedro, Joel, Hernandez, Cristina, Bogdanov, Patricia, Sola-Adell, Cristina et al.
DOI: 10.1007/s00125-017-4388-y

Consensus on management of advanced medullary thyroid carcinoma on behalf of the Working Group of Thyroid Cancer of the Spanish Society of Endocrinology (SEEN) and the Spanish Task Force Group for Orphan and Infrequent Tumors (GETHI).

PMID: 26687366
Journal: Clinical & Translational Oncology
Year: 2016
Reference: Clin Transl Oncol. 2016 Aug;18(8):769-75. doi: 10.1007/s12094-015-1465-x. Epub 2015 Dec 21.
Impact factor: 2.075
Publication type: Review in international publication
Authors: Zafon Llopis, C, Ramon Y Cajal Asensio, T, Gomez Saez, J M, Jimenez-Fonseca, P, Riesco-Eizaguirre, G, Galofre, J C, Navarro Gonzalez, E, Capdevila, J, Grande, E, Santamaria Sandi, J et al.
DOI: 10.1007/s12094-015-1465-x

Topical Administration of GLP-1 Receptor Agonists Prevents Retinal Neurodegeneration in Experimental Diabetes.

PMID: 26384381
Journal: DIABETES
Year: 2016
Reference: Diabetes. 2016 Jan;65(1):172-87. doi: 10.2337/db15-0443. Epub 2015 Sep 17.
Impact factor: 8.784
Publication type: Paper in international publication
Authors: Valverde, Angela M, Simo, Rafael, Arroba, Ana I, Arranz, Jose A, Sola-Adell, Cristina, Garcia-Ramirez, Marta, Hernandez, Cristina, Bogdanov, Patricia, Corraliza, Lidia et al.
DOI: 10.2337/db15-0443

New Oral Hypoglycemic Agents and Cardiovascular Risk. Crossing the Metabolic Border.

PMID: 27687335
Journal: Revista espanola de cardiologia (English ed.)
Year: 2016
Reference: Rev Esp Cardiol (Engl Ed). 2016 Nov;69(11):1088-1097. doi: 10.1016/j.rec.2016.07.008. Epub 2016 Sep 26.
Impact factor: 4.596
Publication type: Review in national publication
Authors: Dalama, Belen, Mesa, Jordi et al.
DOI: 10.1016/j.rec.2016.07.008

Global Assessment of the Impact of Type 2 Diabetes on Sleep through Specific Questionnaires. A Case-Control Study.

PMID: 27315083
Journal: PLoS One
Year: 2016
Reference: PLoS One. 2016 Jun 17;11(6):e0157579. doi: 10.1371/journal.pone.0157579. eCollection 2016.
Impact factor: 3.057
Publication type: Paper in international publication
Authors: Lecube, Albert, Sanchez, Enric, Gomez-Peralta, Fernando, Abreu, Cristina, Valls, Joan, Mestre, Olga, Romero, Odile, Martinez, Maria Dolores, Sampol, Gabriel, Ciudin, Andreea et al.
DOI: 10.1371/journal.pone.0157579

RET Cys634Arg mutation confers a more aggressive multiple endocrine neoplasia type 2A phenotype than Cys634Tyr mutation.

PMID: 25515555
Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY
Year: 2015
Reference: Eur J Endocrinol. 2015 Mar;172(3):301-7. doi: 10.1530/EJE-14-0818. Epub 2014 Dec 16.
Impact factor: 4.069
Publication type: Paper in international publication
Authors: Valdes, Nuria, Navarro, Elena, Mesa, Jordi, Casteras, Anna, Alcazar, Victoria, Lamas, Cristina, Tebar, Javier, CastaNo, Luis, Gaztambide, Sonia, Forga Llenas, Lluis et al.
DOI: 10.1530/EJE-14-0818

Iodine Deficiency Is Higher in Morbid Obesity in Comparison with Late After Bariatric Surgery and Non-obese Women.

PMID: 24908244
Journal: OBESITY SURGERY
Year: 2015
Reference: Obes Surg. 2015 Jan;25(1):85-9. doi: 10.1007/s11695-014-1313-z.
Impact factor: 3.747
Publication type: Paper in international publication
Authors: Tortosa, Frederic, Lecube, Albert, Zafon, Carles, Gromaz, Adoracion, Fort, Jose Manuel, Caubet, Enric, Baena, Juan Antonio et al.
DOI: 10.1007/s11695-014-1313-z

Effect of fenofibrate on retinal neurodegeneration in an experimental model of type 2 diabetes.

PMID: 25029994
Journal: ACTA DIABETOLOGICA
Year: 2015
Reference: Acta Diabetol. 2015 Feb;52(1):113-22. doi: 10.1007/s00592-014-0610-2. Epub 2014 Jul 17.
Impact factor: 2.399
Publication type: Paper in international publication
Authors: Bogdanov, Patricia, Hernandez, Cristina, Corraliza, Lidia, Simo, Rafael, Carvalho, Andrea R et al.
DOI: 10.1007/s00592-014-0610-2

Effect of Glycemic Control on Nocturnal Arterial Oxygen Saturation. A case-control study in Type 2 Diabetic patients.

PMID: 25043292
Journal: Journal of Diabetes
Year: 2015
Reference: J Diabetes. 2015 Jan;7(1):133-8. doi: 10.1111/1753-0407.12197. Epub 2014 Sep 10.
Impact factor: 1.932
Publication type: Paper in international publication
Authors: Lecube, Albert, Ciudin, Andreea, Sampol, Gabriel, Valladares, Silvia, Hernandez, Cristina, Simo, Rafael et al.
DOI: 10.1111/1753-0407.12197

Overexpression of Hemopexin in the Diabetic Eye: A new pathogenic candidate for diabetic macular edema.

PMID: 23620477
Journal: DIABETES CARE
Year: 2013
Reference: Diabetes Care. 2013 Sep;36(9):2815-21. doi: 10.2337/dc12-2634. Epub 2013 Apr 25.
Impact factor: 7.735
Publication type: Paper in international publication
Authors: Hernandez, Cristina, Garcia-Ramirez, Marta, Simo, Rafael et al.
DOI: 10.2337/dc12-2634

Topical administration of somatostatin prevents retinal neurodegeneration in experimental diabetes.

PMID: 23474487
Journal: DIABETES
Year: 2013
Reference: Diabetes. 2013 Jul;62(7):2569-78. doi: 10.2337/db12-0926. Epub 2013 Mar 8.
Impact factor: 7.895
Publication type: Paper in international publication
Authors: Hernandez, Cristina, Garcia-Ramirez, Marta, Corraliza, Lidia, Fernandez-Carneado, Jimena, Farrera-Sinfreu, Josep, Ponsati, Berta, Gonzalez-Rodriguez, Agueda, Martinez-Valverde, Angela, Simo, Rafael et al.
DOI: 10.2337/db12-0926

Internet of Things and bariatric surgery follow-up: Comparative study of standard and IoT follow-up.

PMID: 23470010
Journal: MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES
Year: 2013
Reference: Minim Invasive Ther Allied Technol. 2013 Sep;22(5):304-11. doi: 10.3109/13645706.2013.779282. Epub 2013 Mar 8.
Impact factor: 1.186
Publication type: Paper in international publication
Authors: Vilallonga, Ramon, Lecube, Albert, Fort, Jose Manuel, Boleko, Maria Angeles, Hidalgo, Marta, Armengol, Manel et al.
DOI: 10.3109/13645706.2013.779282

Soluble CD40 ligand in morbidly obese patients: effect of body mass index on recovery to normal levels after gastric bypass surgery.

PMID: 23426590
Journal: ARCHIVES OF SURGERY
Year: 2013
Reference: JAMA Surg. 2013 Feb;148(2):151-6. doi: 10.1001/jamasurgery.2013.419.
Impact factor: 4.1
Publication type: Paper in international publication
Authors: Peinado-Onsurbe, Julia, Vargas, Victor, Baena-Fustegueras, Juan A, Pardina, Eva, Balada, Eva, Ferrer, Roser, Catalan, Roberto, Rivero, Joaquin, Casals, Isidre, Lecube, Albert et al.
DOI: 10.1001/jamasurgery.2013.419

Beneficial effects of fenofibrate in retinal pigment epithelium by the modulation of stress and survival signaling under diabetic conditions.

PMID: 21826649
Journal: JOURNAL OF CELLULAR PHYSIOLOGY
Year: 2012
Reference: J Cell Physiol. 2012 Jun;227(6):2352-62. doi: 10.1002/jcp.22970.
Impact factor: 3.874
Publication type: Paper in international publication
Authors: , , , , , , et al.
DOI: 10.1002/jcp.22970

Potential Role of Tumor Necrosis Factor-alpha in Downregulating Sex Hormone-Binding Globulin.

PMID: 22210320
Journal: DIABETES
Year: 2012
Reference: Diabetes. 2012 Feb;61(2):372-82. Epub 2011 Dec 30.
Impact factor: 8.286
Publication type: Paper in international publication
Authors: , , , , et al.
DOI: 10.2337/db11-0727

Molecular Mechanism of TNFalpha-Induced Down-Regulation of SHBG Expression.

PMID: 22301786
Journal: MOLECULAR ENDOCRINOLOGY
Year: 2012
Reference: Mol Endocrinol. 2012 Mar;26(3):438-46. doi: 10.1210/me.2011-1321. Epub 2012 Feb 2.
Impact factor: 4.544
Publication type: Paper in international publication
Authors: , , , , , et al.
DOI: 10.1210/me.2011-1321

Diabetes is the main factor accounting for hypomagnesemia in obese subjects.

PMID: 22291997
Journal: PLoS One
Year: 2012
Reference: PLoS One. 2012;7(1):e30599. Epub 2012 Jan 24.
Impact factor: 4.092
Publication type: Paper in international publication
Authors: Lecube, Albert, Baena-Fustegueras, Juan Antonio, Fort, Jose Manuel, Pelegri, Dolors, Hernandez, Cristina, Simo, Rafael et al.
DOI: 10.1371/journal.pone.0030599

The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier-implications for the pathogenesis of diabetic retinopathy.

PMID: 20182540
Journal: JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
Year: 2010
Reference: J Biomed Biotechnol. 2010;2010:190724. Epub 2010 Feb 17.
Impact factor: 1.75
Publication type: Review in international publication
Authors: Simo, Rafael, Villarroel, Marta, Corraliza, Lidia, Hernandez, Cristina, Garcia-Ramirez, Marta et al.
DOI: 10.1155/2010/190724

Lipopolysaccharide-binding protein and soluble CD14 in the vitreous fluid of patients with proliferative diabetic retinopathy.

PMID: 20175275
Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Year: 2010
Reference: Retina. 2010 Feb;30(2):345-52.
Impact factor: 2.932
Publication type: Paper in international publication
Authors: Hernandez, Cristina, Ortega, Francisco, Garcia-Ramirez, Marta, Villarroel, Marta, Casado, Joan, Garcia-Pascual, Luis, Fernandez-Real, Jose Manuel, Simo, Rafael et al.
DOI:

Glucose abnormalities in non-alcoholic fatty liver disease and chronic hepatitis C virus infection: the role of iron overload.

PMID: 19444865
Journal: DIABETES-METABOLISM RESEARCH AND REVIEWS
Year: 2009
Reference: Diabetes Metab Res Rev. 2009 Jul;25(5):403-10.
Impact factor: 3.149
Publication type: Review in international publication
Authors: Lecube, Albert, Hernandez, Cristina, Simo, Rafael et al.
DOI: 10.1002/dmrr.972

Interphotoreceptor retinoid-binding protein (IRBP) is downregulated at early stages of diabetic retinopathy.

PMID: 19823802
Journal: DIABETOLOGIA
Year: 2009
Reference: Diabetologia. 2009 Dec;52(12):2633-41.
Impact factor: 6.418
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1007/s00125-009-1548-8

Effects of high glucose concentration on the barrier function and the expression of tight junction proteins in human retinal pigment epithelial cells.

PMID: 19660451
Journal: EXPERIMENTAL EYE RESEARCH
Year: 2009
Reference: Exp Eye Res. 2009 Dec;89(6):913-20.
Impact factor: 2.579
Publication type: Paper in international publication
Authors: , , , , et al.
DOI: 10.1016/j.exer.2009.07.017

High glucose concentration leads to differential expression of tight junction proteins in human retinal pigment epithelial cells.

PMID: 19627712
Journal: Endocrinol Nutr
Year: 2009
Reference: Endocrinol Nutr. 2009 Feb;56(2):53-8.
Impact factor:
Publication type: Letter or abstract
Authors: Villarroel, Marta, Garcia-Ramirez, Marta, Corraliza, Lidia, Hernandez, Cristina, Simo, Rafael et al.
DOI: 10.1016/S1575-0922(09)70552-2

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The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.

This investment from EIT Health in the project will enable D-Sight to progress in the clinical development of its groundbreaking treatment for the early stages of diabetic retinopathy.

This initiative of the ”la Caixa” Foundation offers the selected entrepreneurial scientists financial support and support through individual mentoring and training.