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Diabetes and Metabolism

The Diabetes and Metabolism Research Group is search is lead by Dr. Rafael Simó (Hirsch index:54), Head of the Endocrinology Department, Professor of Medicine & Endocrinology at UAB and current President of the European Association for the Study of Diabetes-Eye Complications. The group consists of 7 senior clinical investigators, 4 basic post-doctoral researchers, 4 pre-doc researchers, 3 laboratory technicians and one coordinator of clinical assays.  

The group belongs to “CIBER” of Diabetes and Associated Metabolic Diseases (CIBERDEM. ISCIII) and has been recognized as consolidated group by the Generalitat de Catalunya (AQU/AGAUR).

Since 2014 this group has been qualified as outstanding in the evaluations performed by the ANEP, CIBERDEM and the external Scientific Advisory Board of VHIR. 

The main lines of research are:

  • Complications of diabetes (in particular diabetic retinopathy)
  • Obesity and its co-morbidities
  • Type 2 diabetes and cognitive impairment
  • Thyroid diseases
  • Hospital Nutrition. 

Team

Kathleen Ramirez Tucas

Kathleen Ramirez Tucas

Predoctoral researcher
Diabetes and Metabolism
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Lorena Ramos Pérez

Lorena Ramos Pérez

Research technician
Diabetes and Metabolism
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Marc Rivas Agudo

Marc Rivas Agudo

Diabetes and Metabolism
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Maria Llorian Salvador

Maria Llorian Salvador

Postdoctoral researcher
Diabetes and Metabolism
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Marta Sánchez Pérez

Marta Sánchez Pérez

Diabetes and Metabolism
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Mercè Abad Martín

Mercè Abad Martín

Research technician
Diabetes and Metabolism
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Kathleen Ramirez Tucas

Kathleen Ramirez Tucas

Predoctoral researcher
Diabetes and Metabolism
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Lorena Ramos Pérez

Lorena Ramos Pérez

Research technician
Diabetes and Metabolism
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Marc Rivas Agudo

Marc Rivas Agudo

Diabetes and Metabolism
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Maria Llorian Salvador

Maria Llorian Salvador

Postdoctoral researcher
Diabetes and Metabolism
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Marta Sánchez Pérez

Marta Sánchez Pérez

Diabetes and Metabolism
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Mercè Abad Martín

Mercè Abad Martín

Research technician
Diabetes and Metabolism
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Projects

Diabetis i metabolisme

IP: Rafael Simó Canonge
Collaborators: Josep A Villena Delgado, Carles Zafon Llopis, Cristina Hernández Pascual, David Martinez Selva, Rosario Pardo Diaz, Angel Michael Ortiz Zuñiga, Andreea Ciudin Mihai, Fiorella Ximena Palmas Candia, Ana Maria Ortiz de Urbina Olive, Monica Sanchez Bartres, Lorena Ramos Pérez, Marc Rivas Agudo, Anna Deàs Just, Anna Casteras Román, Alejandra Planas Vilaseca, Betina Biagetti Biagetti, Judit Amigó Farran, Mercè Abad Martín, Marta Comas Martínez, Hugo Ramos Abellan, Rosa Burgos Peláez, David Sabater Martínez, Olga Simó Servat, Patricia Bogdanov Baruj, Maria Llorian Salvador, Enzamaría Fidilio Meli
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 60000
Reference: 2021 SGR 00655
Duration: 01/01/2022 - 30/06/2025

(INFLAMWAT) - Mecanismos involucrados en la resolución de la inflamación del tejido adiposo en respuesta a restricción calórica

IP: Josep A Villena Delgado
Collaborators: Angel Michael Ortiz Zuñiga, Laura Hidalgo Corbacho, Alba Rojano Toimil, Ramón Vilallonga Puy
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 217800
Reference: PID2021-123377OB-I00
Duration: 01/09/2022 - 31/08/2025

Ministerio de Ciencia

Hemopexin: un nuevo factor patogénico en las complicaciones microvasculares de la diabetes.

IP: Cristina Hernández Pascual
Collaborators: Marina Lopez Martinez, Ana Boixadera Espax, Alejandra Planas Vilaseca, Patricia Bogdanov Baruj, Pilar Costa Forner
Funding agency: Instituto de Salud Carlos III
Funding: 139150
Reference: PI22/01670
Duration: 01/01/2023 - 31/12/2025

Impacto de la cirugía bariátrica en la hemodinámica portal en pacientes con obesidad mórbida y NAFLD. Estudio HEYMDAL.

IP: Ramón Vilallonga Puy
Collaborators: Mercedes Pérez Lafuente, Nuria Roson Gradaille, Laura Puente Ramo, Carla Gonzalez Junyent, Marta Comas Martínez, Alba Rojano Toimil, Arturo Cirera De Tudela, Elisa Merino Peña, Clara Pañella Vilamú, Ana Maria Ciscar Bellés, Carlos Petrola Chacón
Funding agency: Instituto de Salud Carlos III
Funding: 171820
Reference: PI22/00880
Duration: 01/01/2023 - 31/12/2025

Publications

SMART DIABETES HOSPITAL: CLINICAL IMPACT IN COMPLEX SURGICAL UNITS OF A TERTIARY HOSPITAL.

PMID: 39240308
Journal: ACTA DIABETOLOGICA
Year: 2024
Reference: Acta Diabetol. 2024 Sep 6. doi: 10.1007/s00592-024-02370-6.
Impact factor:
Publication type: Paper in international publication
Authors: Abadias, Maria Jose; Amigo, Judit; Cuadra, Fatima; Hernandez, Cristina; Ortiz-Zuniga, Angel; Rojano, Alba; Roman, Antonio; Sanchez, Monica; Santos, Marcos Dos; Simo, Rafael et al.
DOI: 10.1007/s00592-024-02370-6

Pre-Surgery Cortisol Levels as Biomarker of Evolution after Bariatric Surgery: Weight Loss and Weight Regain.

PMID: 39274358
Journal: Journal of Clinical Medicine
Year: 2024
Reference: J Clin Med. 2024 Aug 30;13(17):5146. doi: 10.3390/jcm13175146.
Impact factor:
Publication type: Paper in international publication
Authors: Biagetti, Betina; Casteras, Anna; Ciudin, Andreea; Comas, Marta; Diaz-Troyano, Noelia; Ferrer, Roser; Fidilio, Enzamaria; Flores, Vanesa; Giralt, Marina; Vilallonga, Ramon et al.
DOI: 10.3390/jcm13175146

Discrimination and Stigma Associated with Obesity: A Comparative Study between Spain and Egypt - Data from the OBESTIGMA study.

PMID: 39116845
Journal: Obesity Facts
Year: 2024
Reference: Obes Facts. 2024 Aug 8:1-11. doi: 10.1159/000540635.
Impact factor:
Publication type: Paper in international publication
Authors: Barakat-Barakat, Hosam; Canizares, Silvia; Ciudin, Andreea; Cuatrecasas, Guillem; Diaz-Trastoy, Olaia; El-Sallamy, Rania M; Elghazally, Noha M; Flores, Lilliam; Goni, Fernando; Gutierrez-Medina, Sonsoles et al.
DOI: 10.1159/000540635

Sitagliptin eye drops prevent the impairment of retinal neurovascular unit in the new Trpv2(+/-) rat model.

PMID: 39616390
Journal: Journal of Neuroinflammation
Year: 2024
Reference: J Neuroinflammation. 2024 Nov 30;21(1):312. doi: 10.1186/s12974-024-03283-5.
Impact factor:
Publication type: Paper in international publication
Authors: Augustine, Josy; Curtis, Tim M; Hernandez, Cristina; Karan, Burak M; Ramos, Hugo; Simo, Rafael; Stitt, Alan W et al.
DOI: 10.1186/s12974-024-03283-5

Assessment of dyspneic sensation in patients with type 2 diabetes.

PMID: 37635958
Journal: Frontiers in Endocrinology
Year: 2023
Reference: Front Endocrinol (Lausanne). 2023 Aug 10;14:1208020. doi: 10.3389/fendo.2023.1208020. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Arque, Anais; Balsells, Nuria; Garcia-Aguilera, Esther; Gutierrez-Carrasquilla, Liliana; Hernandez, Cristina; Lecube, Albert; Manzanares, Jose Maria; Marti, Raquel; Mateu, Magda; Mizab, Chadia et al.
DOI: 10.3389/fendo.2023.1208020

Diagnosis and clinical management of thrombotic thrombocytopenic purpura (TTP): a consensus statement from the TTP Catalan group.

PMID: 37677097
Journal: Blood Transfusion
Year: 2023
Reference: Blood Transfus. 2023 Sep 4. doi: 10.2450/BloodTransfus.522.
Impact factor:
Publication type: Paper in international publication
Authors: Ancochea, Agueda; Cespedes, Roberto; Cid, Joan; Diaz, Johana A; Diaz, Maribel; Diaz, Maribel; Escoda, Lourdes; Ferrer, Gonzalo J; Garcia, Jose; Garcia, Jose et al.
DOI: 10.2450/BloodTransfus.522

Which diabetes specific patient reported outcomes should be measured in routine care? A systematic review to inform a core outcome set for adults with Type 1 and 2 diabetes mellitus: The European Health Outcomes Observatory (H2O) programme.

PMID: 37672919
Journal: PATIENT EDUCATION AND COUNSELING
Year: 2023
Reference: Patient Educ Couns. 2023 Aug 16;116:107933. doi: 10.1016/j.pec.2023.107933.
Impact factor:
Publication type: Review in international publication
Authors: Delbecque, Laure; Due-Christensen, Mette; Eeg-Olofson, Katarina; Flores, Vanesa; Forbes, Angus; Forde, Rita; Hamilton, Kathryn; Hasler, Yvonne; Hopkins, David; Kautzky-Willer, Alexandra et al.
DOI: 10.1016/j.pec.2023.107933

Impact of Diabetic Foot Multidisciplinary Unit on Incidence of Lower-Extremity Amputations by Diabetic Foot.

PMID: 37685675
Journal: Journal of Clinical Medicine
Year: 2023
Reference: J Clin Med. 2023 Aug 28;12(17):5608. doi: 10.3390/jcm12175608.
Impact factor:
Publication type: Paper in international publication
Authors: Allegue, Nicolas; Biagetti, Betina; Biagetti, Betina; Busquets, Rosa; Busquets, Rosa; Crespo, Almudena; Crespo, Almudena; Fernandez-Hidalgo, Nuria; Fernandez-Hidalgo, Nuria; Gene, Anna et al.
DOI: 10.3390/jcm12175608

Complement activation contributes to subretinal fibrosis through the induction of epithelial-to-mesenchymal transition (EMT) in retinal pigment epithelial cells.

PMID: 35831910
Journal: Journal of Neuroinflammation
Year: 2022
Reference: J Neuroinflammation. 2022 Jul 14;19(1):182. doi: 10.1186/s12974-022-02546-3.
Impact factor:
Publication type: Paper in international publication
Authors: Byrne, Eimear M; Chen, Mei; Little, Karis; Llorian-Salvador, Maria; Szczepan, Manon; Xu, Heping et al.
DOI: 10.1186/s12974-022-02546-3

State-of-the-Art Research on Diabetic Retinopathy.

PMID: 35807075
Journal: Journal of Clinical Medicine
Year: 2022
Reference: J Clin Med. 2022 Jun 30;11(13). pii: jcm11133790. doi: 10.3390/jcm11133790.
Impact factor:
Publication type: Editorail in international publication
Authors: Simo, Rafael et al.
DOI: 10.3390/jcm11133790

Type 1 diabetes and pregnancy: An update on glucose monitoring and insulin treatment.

PMID: 35787359
Journal: Endocrinologia Diabetes y Nutricion
Year: 2022
Reference: Endocrinol Diabetes Nutr (Engl Ed). 2022 Jun-Jul;69(6):433-441. doi: 10.1016/j.endien.2022.06.008. Epub 2022 Jul 2.
Impact factor:
Publication type: Review in international publication
Authors: Amigo, Judit; Corcoy, Rosa et al.
DOI: 10.1016/j.endien.2022.06.008

Transforming growth factor-beta 1: A new factor reducing hepatic SHBG production in liver fibrosis.

PMID: 35762039
Journal: JOURNAL OF CELLULAR PHYSIOLOGY
Year: 2022
Reference: J Cell Physiol. 2022 Sep;237(9):3598-3613. doi: 10.1002/jcp.30818. Epub 2022 Jun 27.
Impact factor:
Publication type: Paper in international publication
Authors: Brianso-Llort, Laura; Fuertes-Rioja, Lidia; Hernandez, Cristina; Ramos-Perez, Lorena; Salcedo-Allende, Maria Teresa; Selva, David M; Simo, Rafael et al.
DOI: 10.1002/jcp.30818

Correction: Late Recovery of Parathyroid Function after Total Thyroidectomy: A Case-Control Study.

PMID: 34560785
Journal: HORMONE AND METABOLIC RESEARCH
Year: 2021
Reference: Horm Metab Res. 2021 Oct;53(10):e5. doi: 10.1055/a-1646-8410. Epub 2021 Sep 24.
Impact factor:
Publication type: Letter or abstract
Authors: Alvarez-Escola, Cristina; Anda, Emma; Baena-Nieto, Gloria; Bandres, Orosia; Carrera, Concepcion Blanco; Corral, Begona Perez; de la Vega, Manel Sahun; Diez, Juan Jose; Donnay, Sergio; Fernandez, Piedad Santiago et al.
DOI: 10.1055/a-1646-8410

Reversal to Normal Anatomy (With Sleeve Gastrectomy) for Severe Hypoglycemia.

PMID: 33381999
Journal: Surgical Innovation
Year: 2021
Reference: Surg Innov. 2021 Oct;28(5):536-543. doi: 10.1177/1553350620984647. Epub 2020 Dec 31.
Impact factor:
Publication type: Paper in international publication
Authors: Armengol, Manel; Caubet, Enric; Ciudin, Andrea; Fort, Jose Manuel; Gonzalez, Oscar; Rodriguez-Luna, Maria Rita; Roriz-Silva, Renato; Ruiz de Gordejuela, Amador; Vilallonga, Ramon et al.
DOI: 10.1177/1553350620984647

Late Recovery of Parathyroid Function after Total Thyroidectomy: A Case-Control Study.

PMID: 34517416
Journal: HORMONE AND METABOLIC RESEARCH
Year: 2021
Reference: Horm Metab Res. 2021 Oct;53(10):654-661. doi: 10.1055/a-1608-1373. Epub 2021 Sep 13.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Escola, Cristina; Anda, Emma; Baena-Nieto, Gloria; Bandres, Orosia; Carrera, Concepcion Blanco; Corral, Begona Perez; de la Vega, Manel Sahun; Donnay, Sergio; Fernandez, Piedad Santiago; Fernandez-Garcia, Jose Carlos et al.
DOI: 10.1055/a-1608-1373

GLP-1 Receptor Agonists in Diabetic Kidney Disease: From Physiology to Clinical Outcomes.

PMID: 34501404
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Aug 31;10(17). pii: jcm10173955. doi: 10.3390/jcm10173955.
Impact factor:
Publication type: Review in international publication
Authors: Ciudin, Andreea; Rojano Toimil, Alba et al.
DOI: 10.3390/jcm10173955

Effectiveness of Laparoscopic Sleeve Gastrectomy in Super-obese and Non-Super-obese Patients.

PMID: 32427745
Journal: SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES
Year: 2020
Reference: Surg Laparosc Endosc Percutan Tech. 2020 May 15. doi: 10.1097/SLE.0000000000000801.
Impact factor:
Publication type: Paper in international publication
Authors: Armengol, Manel; Balibrea, Jose M; Caubet, Enric; Ciudin, Andrea; Fort, Jose M; Gonzalez, Oscar; Hidalgo, Marta; Rodriguez-Luna, Maria R; Roriz-Silva, Renato; Ruiz de Godejuela, Amador Garcia et al.
DOI: 10.1097/SLE.0000000000000801

Looking for solutions to lung dysfunction in type 2 diabetes.

PMID: 32411744
Journal: Annals of Translational Medicine
Year: 2020
Reference: Ann Transl Med. 2020 Apr;8(8):521. doi: 10.21037/atm.2020.03.225.
Impact factor:
Publication type: Editorail in international publication
Authors: Lecube, Albert; Simo, Rafael et al.
DOI: 10.21037/atm.2020.03.225

The Usefulness of Serum Biomarkers in the Early Stages of Diabetic Retinopathy: Results of the EUROCONDOR Clinical Trial.

PMID: 32344735
Journal: Journal of Clinical Medicine
Year: 2020
Reference: J Clin Med. 2020 Apr 24;9(4). pii: jcm9041233. doi: 10.3390/jcm9041233.
Impact factor:
Publication type: Paper in international publication
Authors: Aldington, Stephen J; Bandello, Francesco; Cunha-Vaz, Jose; Egan, Catherine; Frydkjaer-Olsen, Ulrik; Garcia-Arumi, Jose; Gibson, Jonathan; Grauslund, Jakob; Harding, Simon P; Hernandez, Cristina et al.
DOI: 10.3390/jcm9041233

Prognostic Significance of Thyroglobulin Antibodies in Differentiated Thyroid Cancer.

PMID: 32351680
Journal: Journal of thyroid research
Year: 2020
Reference: J Thyroid Res. 2020 Apr 14;2020:8312628. doi: 10.1155/2020/8312628. eCollection 2020.
Impact factor:
Publication type: Paper in international publication
Authors: Castells, Ignasi; Granada, M Luisa; Megia, Ana; Pizarro, Eduarda; Puig-Domingo, Manel; Puig-Jove, Carlos; Reverter, Jordi L; Rosas-Allende, Irene; Zafon, Carles et al.
DOI: 10.1155/2020/8312628

Contribution of Impaired Insulin Signaling to the Pathogenesis of Diabetic Cardiomyopathy.

PMID: 31212580
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2019
Reference: Int J Mol Sci. 2019 Jun 11;20(11). pii: ijms20112833. doi: 10.3390/ijms20112833.
Impact factor:
Publication type: Review in international publication
Authors: Villena, Josep A; Zamora, Monica et al.
DOI: 10.3390/ijms20112833

Analysis of the PD-1/PD-L1 axis in human autoimmune thyroid disease: Insights into pathogenesis and clues to immunotherapy associated thyroid autoimmunity.

PMID: 31182340
Journal: JOURNAL OF AUTOIMMUNITY
Year: 2019
Reference: J Autoimmun. 2019 Sep;103:102285. doi: 10.1016/j.jaut.2019.05.013. Epub 2019 Jun 8.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sierra, Daniel; Casteras, Anna; Colobran, Roger; Costa, Roser Ferrer; de Jesus Gil, Carmen; Gonzalez, Oscar; Iglesias-Felip, Carmela; Marin-Sanchez, Ana; Nuciforo, Paolo; Pujol-Borrell, Ricardo et al.
DOI: 10.1016/j.jaut.2019.05.013

Cytoskeletal transgelin 2 contributes to gender-dependent adipose tissue expandability and immune function.

PMID: 31145872
Journal: FASEB JOURNAL
Year: 2019
Reference: FASEB J. 2019 Aug;33(8):9656-9671. doi: 10.1096/fj.201900479R. Epub 2019 May 30.
Impact factor:
Publication type: Paper in international publication
Authors: Bosch, Fatima; Botas, Patricia; Burcelin, Remy; Buxo, Maria; Caballano-Infantes, Estefania; Castrillon-Rodriguez, Ignacio; Corella, Dolores; Delgado, Elias; Fernandez-Real, Jose M; Fruhbeck, Gema et al.
DOI: 10.1096/fj.201900479R

Diabetic Retinopathy in the Context of Patients with Diabetes.

PMID: 31129667
Journal: OPHTHALMIC RESEARCH
Year: 2019
Reference: Ophthalmic Res. 2019;62(4):211-217. doi: 10.1159/000499541. Epub 2019 May 24.
Impact factor:
Publication type: Review in international publication
Authors: Hernandez, Cristina; Simo, Rafael; Simo-Servat, Olga et al.
DOI: 10.1159/000499541

Pasireotide in acromegaly by aggressive tumors, description of four clinical cases.. Towards a personalized medicine.

PMID: 29371000
Journal: Endocrinologia, diabetes y nutricion
Year: 2018
Reference: Endocrinol Diabetes Nutr. 2018 Feb;65(2):130-132. doi: 10.1016/j.endinu.2017.12.001. Epub 2018 Jan 20.
Impact factor:
Publication type: Paper in national publication
Authors: Biagetti, Betina; Cordero, Esteban; Martinez Saez, Elena; Mesa, Jordi; Obiols, Gabriel et al.
DOI: 10.1016/j.endinu.2017.12.001

Response to oral sucrosomial iron supplementation in patients undergoing bariatric surgery. The BARI-FER study.

PMID: 29233512
Journal: Endocrinologia, diabetes y nutricion
Year: 2018
Reference: Endocrinol Diabetes Nutr. 2018 Jan;65(1):17-20. doi: 10.1016/j.endinu.2017.10.007. Epub 2017 Dec 7.
Impact factor:
Publication type: Paper in national publication
Authors: Balibrea, Jose Maria; Ciudin, Andreea; Hernandez, Cristina; Mesa, Jordi; Simo, Rafael; Simo-Servat, Olga; Vilallonga, Ramon et al.
DOI: 10.1016/j.endinu.2017.10.007

Insurance Appeals for Pediatric Reconstructive Surgery: A Micro Cost Analysis and How-to Guide.

PMID: 29389708
Journal: ANNALS OF PLASTIC SURGERY
Year: 2018
Reference: Ann Plast Surg. 2018 Mar;80(3):198-204. doi: 10.1097/SAP.0000000000001340.
Impact factor:
Publication type: Paper in international publication
Authors: Braun, Joseph L; Braun, Tara L; Hernandez, Cristina; Monson, Laura A et al.
DOI: 10.1097/SAP.0000000000001340

Clinical predictors of candidemia in medical non-neutropenic, non-ICU patients. The CaMed score.

PMID: 30375125
Journal: INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
Year: 2018
Reference: Int J Clin Pract. 2018 Dec;72(12):e13275. doi: 10.1111/ijcp.13275. Epub 2018 Oct 30.
Impact factor:
Publication type: Paper in international publication
Authors: Cabo-Magadan, Rebeca; Cardozo, Cristina; Coronado-Alvarez, Nieves M; Duenas, Carlos; Hernandez, Cristina; Luna, Juan D; Mensa, Josep; Munoz-Medina, Leopoldo; Parra-Ruiz, Jorge; Portillo-Tunon, Vera et al.
DOI: 10.1111/ijcp.13275

Selective sentinel lymph node biopsy in papillary thyroid carcinoma in patients with no preoperative evidence of lymph node metastasis.

PMID: 28895542
Journal: Endocrinologia, diabetes y nutricion
Year: 2017
Reference: Endocrinol Diabetes Nutr. 2017 Oct;64(8):451-455. doi: 10.1016/j.endinu.2017.05.001. Epub 2017 Jun 29.
Impact factor:
Publication type: Paper in national publication
Authors: Castell, Joan; Caubet, Enric; Fort, Jose Manuel; Garcia-Burillo, Amparo; Gonzalez, Oscar; Iglesias, Carmela; Mesa, Jordi; Ramon Y Cajal, Santiago; Roca, Isabel; Serres, Xavier et al.
DOI: 10.1016/j.endinu.2017.05.001

Effects of Sotagliflozin Added to Insulin in Patients with Type 1 Diabetes.

PMID: 28899222
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2017
Reference: N Engl J Med. 2017 Dec 14;377(24):2337-2348. doi: 10.1056/NEJMoa1708337. Epub 2017 Sep 13.
Impact factor:
Publication type: Paper in international publication
Authors: Banks, Phillip; Buse, John B; Danne, Thomas; Davies, Melanie J; Fulcher, Gregory R; Garg, Satish K; Gesty-Palmer, Diane; Henry, Robert R; Kushner, Jake A; Lapuerta, Pablo et al.
DOI: 10.1056/NEJMoa1708337

Calcium dobesilate prevents the oxidative stress and inflammation induced by diabetes in the retina of db/db mice.

PMID: 28847447
Journal: JOURNAL OF DIABETES AND ITS COMPLICATIONS
Year: 2017
Reference: J Diabetes Complications. 2017 Oct;31(10):1481-1490. doi: 10.1016/j.jdiacomp.2017.07.009. Epub 2017 Jul 26.
Impact factor:
Publication type: Paper in international publication
Authors: Bogdanov, Patricia; Garcia-Ramirez, Marta; Hernandez, Cristina; Pasquali, Christian; Sampedro, Joel; Simo, Rafael; Simo-Servat, Olga; Sola-Adell, Cristina; Valeri, Marta et al.
DOI: 10.1016/j.jdiacomp.2017.07.009

Diabetic Retinopathy Phenotypes of Progression to Macular Edema: Pooled Analysis From Independent Longitudinal Studies of up to 2 Years' Duration.

PMID: 28785768
Journal: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Year: 2017
Reference: Invest Ophthalmol Vis Sci. 2017 May 1;58(6):BIO206-BIO210. doi: 10.1167/iovs.17-21780.
Impact factor:
Publication type: Paper in international publication
Authors: Costa, Miguel; Cunha-Vaz, Jose; Ribeiro, Luisa; Simo, Rafael et al.
DOI: 10.1167/iovs.17-21780

Effects of sardine-enriched diet on metabolic control, inflammation and gut microbiota in drug-naive patients with type 2 diabetes: a pilot randomized trial.

PMID: 27090218
Journal: Lipids in Health and Disease
Year: 2016
Reference: Lipids Health Dis. 2016 Apr 18;15(1):78. doi: 10.1186/s12944-016-0245-0.
Impact factor:
Publication type: Paper in international publication
Authors: Aranda, Gloria; Balfego, Mariona; Canivell, Silvia; Fontalba, Maria; Gomis, Ramon; Hanzu, Felicia A; Hernandez, Cristina; Linares, Francisca; Martinez-Medina, Margarita; Mur, Teresa et al.
DOI: 10.1186/s12944-016-0245-0

Correlation between Retinal Vessel Calibre and Neurodegeneration in Patients with Type 2 Diabetes Mellitus in the European Consortium for the Early Treatment of Diabetic Retinopathy (EUROCONDOR).

PMID: 27054695
Journal: OPHTHALMIC RESEARCH
Year: 2016
Reference: Ophthalmic Res. 2016;56(1):10-6. doi: 10.1159/000444396. Epub 2016 Apr 8.
Impact factor:
Publication type: Paper in international publication
Authors: Cunha-Vaz, Jose; Frydkjaer-Olsen, Ulrik; Grauslund, Jakob; Peto, Tunde; Simo, Rafael; Soegaard Hansen, Rasmus et al.
DOI: 10.1159/000444396

The placebo effect in thyroid cancer: a meta-analysis.

PMID: 26764417
Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY
Year: 2016
Reference: Eur J Endocrinol. 2016 Apr;174(4):465-72. doi: 10.1530/EJE-15-1119. Epub 2016 Jan 13.
Impact factor:
Publication type: Paper in international publication
Authors: Galofre, Juan C; Guillen-Grima, Francisco; Llavero-Valero, Maria; Zafon, Carles et al.
DOI: 10.1530/EJE-15-1119

Gene expression profiling in hearts of diabetic mice uncovers a potential role of estrogen-related receptor gamma in diabetic cardiomyopathy.

PMID: 27062900
Journal: MOLECULAR AND CELLULAR ENDOCRINOLOGY
Year: 2016
Reference: Mol Cell Endocrinol. 2016 Jul 15;430:77-88. doi: 10.1016/j.mce.2016.04.004. Epub 2016 Apr 7.
Impact factor:
Publication type: Paper in international publication
Authors: Cases, Ildefonso; Feliu, Juan E; Garcia-Dorado, David; Hernandez, Cristina; Lasheras, Jaime; Pardo, Rosario; Poncelas, Marcos; Riu, Efren; Ruiz-Meana, Marisol; Simo, Rafael et al.
DOI: 10.1016/j.mce.2016.04.004

Obesity induced by high fat diet attenuates postinfarct myocardial remodeling and dysfunction in adult B6D2F1 mice.

PMID: 25953257
Journal: J MOL CELL CARDIOL
Year: 2015
Reference: J Mol Cell Cardiol. 2015 Jul;84:154-61. doi: 10.1016/j.yjmcc.2015.04.023. Epub 2015 May 5.
Impact factor:
Publication type: Paper in international publication
Authors: Baneras, Jordi; Garcia-Dorado, David; Inserte, Javier; Poncelas, Marcos; Rodriguez-Sinovas, Antonio; Simo, Rafael; Vilardosa, Ursula et al.
DOI: 10.1016/j.yjmcc.2015.04.023

Novel approaches for treating diabetic retinopathy based on recent pathogenic evidence.

PMID: 25936649
Journal: PROG RETIN EYE RES
Year: 2015
Reference: Prog Retin Eye Res. 2015 Sep;48:160-80. doi: 10.1016/j.preteyeres.2015.04.003. Epub 2015 Apr 30.
Impact factor:
Publication type: Paper in international publication
Authors: Hernandez, Cristina; Simo, Rafael et al.
DOI: 10.1016/j.preteyeres.2015.04.003

Non-traditional systemic treatments for diabetic retinopathy: an evidence-based review.

PMID: 25989912
Journal: CURR MED CHEM
Year: 2015
Reference: Curr Med Chem. 2015;22(21):2580-9.
Impact factor:
Publication type: Review in international publication
Authors: Ballarini, Stefania; Cunha-Vaz, Jose; Haller, Hermann; Ji, Linong; Simo, Rafael; Wong, Tien Y; Zimmet, Paul et al.
DOI:

Novel insights in SHBG regulation and clinical implications.

PMID: 26044465
Journal: TRENDS ENDOCRIN MET
Year: 2015
Reference: Trends Endocrinol Metab. 2015 Jul;26(7):376-83. doi: 10.1016/j.tem.2015.05.001. Epub 2015 Jun 1.
Impact factor:
Publication type: Paper in international publication
Authors: Barbosa-Desongles, Anna; Hernandez, Cristina; Saez-Lopez, Cristina; Selva, David M; Simo, Rafael et al.
DOI: 10.1016/j.tem.2015.05.001

Past and present in abdominal surgery management for Cushing's syndrome.

PMID: 26770719
Journal: SAGE open medicine
Year: 2014
Reference: SAGE Open Med. 2014 Mar 31;2:2050312114528905. doi: 10.1177/2050312114528905. eCollection 2014.
Impact factor: 0
Publication type: Paper in international publication
Authors: Vilallonga, Ramon, Zafon, Carles, Fort, Jose Manuel, Mesa, Jordi, Armengol, Manel et al.
DOI: 10.1177/2050312114528905

Glycemic control parameters in insulin-naive patients with uncontrolled type 2 diabetes referred to endocrinologists, and degree of implementation of the national Spanish consensus for the management of hyperglycemia.

PMID: 25260336
Journal: Endocrinologia y nutricion : organo de la Sociedad
Year: 2014
Reference: Endocrinol Nutr. 2014 Dec;61(10):541-7. doi: 10.1016/j.endonu.2014.06.004. Epub 2014 Sep 24.
Impact factor: 0
Publication type: Paper in national publication
Authors: Casal, Florentino, Dalama, Belen, Varillas, Francisco, Villarroel, Africa, Soto, Alfonso, Barbera, Gloria, Azriel, Sharona et al.
DOI: 10.1016/j.endonu.2014.06.004

Decreased lipases and fatty acid and glycerol transporter could explain reduced fat in diabetic morbidly obese.

PMID: 25132069
Journal: OBESITY FACTS
Year: 2014
Reference: Obesity (Silver Spring). 2014 Nov;22(11):2379-87. doi: 10.1002/oby.20861. Epub 2014 Aug 6.
Impact factor: 1.705
Publication type: Paper in international publication
Authors: Peinado-Onsurbe, Julia, Fort, Jose Manuel, Ferrer, Roser, Pardina, Eva, Rossell, Joana, Baena-Fustegueras, Juan Antonio, Lecube, Albert, Balibrea, Jose Maria, Caubet, Enric, Gonzalez, Oscar et al.
DOI: 10.1002/oby.20861

The db/db mouse: a useful model for the study of diabetic retinal neurodegeneration.

PMID: 24837086
Journal: PLOS ONE
Year: 2014
Reference: PLoS One. 2014 May 16;9(5):e97302. doi: 10.1371/journal.pone.0097302. eCollection 2014.
Impact factor: 3.534
Publication type: Paper in international publication
Authors: Bogdanov, Patricia, Corraliza, Lidia, A Villena, Josep, Carvalho, Andrea R, Garcia-Arumi, Jose, Ramos, David, Ruberte, Jesus, Simo, Rafael, Hernandez, Cristina et al.
DOI: 10.1371/journal.pone.0097302

Overexpression of Hemopexin in the Diabetic Eye: A new pathogenic candidate for diabetic macular edema.

PMID: 23620477
Journal: DIABETES CARE
Year: 2013
Reference: Diabetes Care. 2013 Sep;36(9):2815-21. doi: 10.2337/dc12-2634. Epub 2013 Apr 25.
Impact factor:
Publication type: Paper in international publication
Authors: Garcia-Ramirez, Marta; Hernandez, Cristina; Simo, Rafael et al.
DOI: 10.2337/dc12-2634

Topical administration of somatostatin prevents retinal neurodegeneration in experimental diabetes.

PMID: 23474487
Journal: DIABETES
Year: 2013
Reference: Diabetes. 2013 Jul;62(7):2569-78. doi: 10.2337/db12-0926. Epub 2013 Mar 8.
Impact factor:
Publication type: Paper in international publication
Authors: Corraliza, Lidia; Farrera-Sinfreu, Josep; Fernandez-Carneado, Jimena; Garcia-Ramirez, Marta; Gonzalez-Rodriguez, Agueda; Hernandez, Cristina; Martinez-Valverde, Angela; Ponsati, Berta; Simo, Rafael et al.
DOI: 10.2337/db12-0926

Internet of Things and bariatric surgery follow-up: Comparative study of standard and IoT follow-up.

PMID: 23470010
Journal: MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES
Year: 2013
Reference: Minim Invasive Ther Allied Technol. 2013 Sep;22(5):304-11. doi: 10.3109/13645706.2013.779282. Epub 2013 Mar 8.
Impact factor:
Publication type: Paper in international publication
Authors: Armengol, Manel; Boleko, Maria Angeles; Fort, Jose Manuel; Hidalgo, Marta; Lecube, Albert; Vilallonga, Ramon et al.
DOI: 10.3109/13645706.2013.779282

Molecular Implications of the PPARs in the Diabetic Eye.

PMID: 23431285
Journal: PPAR Research
Year: 2013
Reference: PPAR Res. 2013;2013:686525. doi: 10.1155/2013/686525. Epub 2013 Feb 4.
Impact factor:
Publication type: Paper in international publication
Authors: Ciudin, Andreea; Hernandez, Cristina; Simo, Rafael et al.
DOI: 10.1155/2013/686525

Non-invasive methods of glucose measurement: current status and future perspectives.

PMID: 22414058
Journal: Current diabetes reviews
Year: 2012
Reference: Curr Diabetes Rev. 2012 Jan 1;8(1):48-54.
Impact factor:
Publication type: Letter or abstract
Authors: Ciudin, Andreea; Hernandez, Cristina; Simo, Rafael et al.
DOI:

Arterial Stiffness Is Increased in Patients With Type 1 Diabetes Without Cardiovascular Disease: A potential role of low-grade inflammation.

PMID: 22357186
Journal: DIABETES CARE
Year: 2012
Reference: Diabetes Care. 2012 May;35(5):1083-9. doi: 10.2337/dc11-1475. Epub 2012 Feb 22.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.2337/dc11-1475

Prevention and Treatment of Diabetic Retinopathy: Evidence from Large, Randomized Trials. The Emerging role of Fenofibrate.

PMID: 21864248
Journal: Reviews on recent clinical trials
Year: 2012
Reference: Rev Recent Clin Trials. 2012 Feb 1;7(1):71-80.
Impact factor:
Publication type: Letter or abstract
Authors: ; et al.
DOI:

Pref-1 in brown adipose tissue: specific involvement in brown adipocyte differentiation and regulatory role of C/EBPdelta

PMID: 22324440
Journal: BIOCHEMICAL JOURNAL
Year: 2012
Reference: Biochem J. 2012 May 1;443(3):799-810. doi: 10.1042/BJ20111714.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; et al.
DOI: 10.1042/BJ20111714

Treatment of thyroid cancer with the new oral agents.

PMID: 21859897
Journal: ANNALS OF ONCOLOGY
Year: 2011
Reference: Ann Oncol. 2011 Oct;22(10):2343. Epub 2011 Aug 22.
Impact factor: 6.452
Publication type: Letter or abstract
Authors: Lucas-Martin, A, Menendez-Torre, E, Pereg, V, Perez-Corral, B, Santamaria, J, Riesco-Eizaguirre, G, Zafon, C, Donnay, S, Calleja, A, Escola, C A et al.
DOI: 10.1093/annonc/mdr409

Phagocytic activity is impaired in type 2 diabetes mellitus and increases after metabolic improvement.

PMID: 21876749
Journal: PLoS One
Year: 2011
Reference: PLoS One. 2011;6(8):e23366. Epub 2011 Aug 18.
Impact factor: 4.411
Publication type: Paper in international publication
Authors: Pachon, Gisela, Petriz, Jordi, Hernandez, Cristina, Simo, Rafael, Lecube, Albert et al.
DOI: 10.1371/journal.pone.0023366

Measuring Permeability in Human Retinal Epithelial Cells (ARPE-19): Implications for the Study of Diabetic Retinopathy.

PMID: 21874452
Journal: Methods in molecular biology
Year: 2011
Reference: Methods Mol Biol. 2011;763:179-94.
Impact factor:
Publication type: Letter or abstract
Authors: Garcia-Ramirez, Marta, Villarroel, Marta, Corraliza, Lidia, Hernandez, Cristina, Simo, Rafael et al.
DOI: 10.1007/978-1-61779-191-8_12

Capillary beta-hydroxybutyrate determination for monitoring diabetic ketoacidosis.

PMID: 21737365
Journal: Endocrinol Nutr
Year: 2011
Reference: Endocrinol Nutr. 2011 Aug-Sep;58(7):347-52. Epub 2011 Jul 6.
Impact factor:
Publication type: Letter or abstract
Authors: , , , , , , , , et al.
DOI: 10.1016/j.endonu.2011.05.003

The Relationships Between IGF-1 and CRP, NO, Leptin, and Adiponectin During Weight Loss in the Morbidly Obese.

PMID: 20195789
Journal: OBESITY SURGERY
Year: 2010
Reference: Obes Surg. 2010 May;20(5):623-32.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; et al.
DOI: 10.1007/s11695-010-0103-5

The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier-implications for the pathogenesis of diabetic retinopathy.

PMID: 20182540
Journal: JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
Year: 2010
Reference: J Biomed Biotechnol. 2010;2010:190724. Epub 2010 Feb 17.
Impact factor:
Publication type: Review in international publication
Authors: Corraliza, Lidia; Garcia-Ramirez, Marta; Hernandez, Cristina; Simo, Rafael; Villarroel, Marta et al.
DOI: 10.1155/2010/190724

Lipopolysaccharide-binding protein and soluble CD14 in the vitreous fluid of patients with proliferative diabetic retinopathy.

PMID: 20175275
Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Year: 2010
Reference: Retina. 2010 Feb;30(2):345-52.
Impact factor:
Publication type: Paper in international publication
Authors: Casado, Joan; Fernandez-Real, Jose Manuel; Garcia-Pascual, Luis; Garcia-Ramirez, Marta; Hernandez, Cristina; Ortega, Francisco; Simo, Rafael; Villarroel, Marta et al.
DOI:

Differences in the Form of Presentation between Papillary Microcarcinomas and Papillary Carcinomas of Larger Size.

PMID: 21209704
Journal: Journal of thyroid research
Year: 2010
Reference: J Thyroid Res. 2010 Dec 14;2011:639156.
Impact factor:
Publication type: Letter or abstract
Authors: Zafon, Carles, Baena, Juan Antonio, Castellvi, Josep, Obiols, Gabriel, Monroy, Gabriela, Mesa, Jordi et al.
DOI: 10.4061/2011/639156

High glucose concentration leads to differential expression of tight junction proteins in human retinal pigment epithelial cells.

PMID: 19627712
Journal: Endocrinol Nutr
Year: 2009
Reference: Endocrinol Nutr. 2009 Feb;56(2):53-8.
Impact factor:
Publication type: Letter or abstract
Authors: Corraliza, Lidia; Garcia-Ramirez, Marta; Hernandez, Cristina; Simo, Rafael; Villarroel, Marta et al.
DOI: 10.1016/S1575-0922(09)70552-2

Fat and aging: a tale of two tissues.

PMID: 20021402
Journal: Current aging science
Year: 2009
Reference: Curr Aging Sci. 2009 Jul;2(2):83-94. doi: 10.2174/1874609810902020083.
Impact factor: 0
Publication type: Paper in international publication
Authors: Zafon, Carles et al.
DOI: 10.2174/1874609810902020083

[The mitogen-activated protein kinase (MAPK) signaling pathway in papillary thyroid cancer. From the molecular bases to clinical practice].

PMID: 19627734
Journal: Endocrinol Nutr
Year: 2009
Reference: Endocrinol Nutr. 2009 Apr;56(4):176-86. doi: 10.1016/S1575-0922(09)70982-9. Epub 2009 Jun 11.
Impact factor: 0
Publication type: Review in national publication
Authors: Zafon, Carles, Obiols, Gabriel et al.
DOI: 10.1016/S1575-0922(09)70982-9

Increased expression and activity of hepatic lipase in the liver of morbidly obese adult patients in relation to lipid content.

PMID: 18972174
Journal: OBESITY SURGERY
Year: 2009
Reference: Obes Surg. 2009 Jul;19(7):894-904.
Impact factor: 2.913
Publication type: Paper in international publication
Authors: Peinado-Onsurbe, Julia, Vargas, Victor, Pardina, Eva, Baena-Fustegueras, Juan A, Catalan, Roberto, Galard, Rosa, Lecube, Albert, Fort, Jose M, Allende, Helena et al.
DOI: 10.1007/s11695-008-9739-9

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The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.

This investment from EIT Health in the project will enable D-Sight to progress in the clinical development of its groundbreaking treatment for the early stages of diabetic retinopathy.

This initiative of the ”la Caixa” Foundation offers the selected entrepreneurial scientists financial support and support through individual mentoring and training.