Diabetes and Metabolism
The Diabetes and Metabolism Research Group is search is lead by Dr. Rafael Simó (Hirsch index:54), Head of the Endocrinology Department, Professor of Medicine & Endocrinology at UAB and current President of the European Association for the Study of Diabetes-Eye Complications. The group consists of 7 senior clinical investigators, 4 basic post-doctoral researchers, 4 pre-doc researchers, 3 laboratory technicians and one coordinator of clinical assays.
The group belongs to “CIBER” of Diabetes and Associated Metabolic Diseases (CIBERDEM. ISCIII) and has been recognized as consolidated group by the Generalitat de Catalunya (AQU/AGAUR).
Since 2014 this group has been qualified as outstanding in the evaluations performed by the ANEP, CIBERDEM and the external Scientific Advisory Board of VHIR.
The main lines of research are:
- Complications of diabetes (in particular diabetic retinopathy)
- Obesity and its co-morbidities
- Type 2 diabetes and cognitive impairment
- Thyroid diseases
- Hospital Nutrition.
Team
Publications
Regulatory T cell expansion prevents retinal degeneration in type 2 diabetes.
PMID: 39716335
Journal: Journal of Neuroinflammation
Year: 2024
Reference: J Neuroinflammation. 2024 Dec 23;21(1):328. doi: 10.1186/s12974-024-03323-0.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Guaita, Anna; Bogdanov, Patricia; de la Fuente, Alerie G; Deas-Just, Anna; Duarri, Anna; Garcia-Ramirez, Marta; Gomez-Sanchez, Jose A; Hernandez, Cristina; Llorian-Salvador, Maria; Perez-Martinez, Daniel et al.
DOI: 10.1186/s12974-024-03323-0
Ocular and Plasma Pharmacokinetics of Sitagliptin Eye Drops: Preclinical Data.
PMID: 39770421
Journal: Pharmaceuticals
Year: 2024
Reference: Pharmaceuticals (Basel). 2024 Nov 24;17(12):1579. doi: 10.3390/ph17121579.
Impact factor:
Publication type: Paper in international publication
Authors: Hernandez, Cristina; Letondor, Anne; Ramos, Hugo; Simo, Rafael et al.
DOI: 10.3390/ph17121579
Topical ocular administration of DPP-IV inhibitors: a new approach for treating diabetes-induced retinal neurodegeneration.
PMID: 37843198
Journal:
Year: 2024
Reference: Neural Regen Res. 2024 Apr;19(4):713-714. doi: 10.4103/1673-5374.353492.
Impact factor:
Publication type: Paper in international publication
Authors: Hernandez, Cristina; Simo, Rafael et al.
DOI: 10.4103/1673-5374.353492
Hyponatremia after COVID-19 is frequent in the first year and increases re-admissions.
PMID: 38182711
Journal: Scientific Reports
Year: 2024
Reference: Sci Rep. 2024 Jan 5;14(1):595. doi: 10.1038/s41598-023-50970-z.
Impact factor:
Publication type: Paper in international publication
Authors: Anderssen-Nordahl, Emilie; Biagetti, Betina; Campos-Varela, Isabel; Gonzalez-Sans, Didac; Miarons, Marta; Pilia, Maria Florencia; Puig-Perez, Albert; Sanchez-Montalva, Adrian; Simo, Rafael et al.
DOI: 10.1038/s41598-023-50970-z
Blocking hemopexin with specific antibodies: a new strategy for treating diabetic retinopathy.
PMID: 37722135
Journal: DIABETES
Year: 2023
Reference: Diabetes. 2023 Sep 18:db230027. doi: 10.2337/db23-0027.
Impact factor:
Publication type: Paper in international publication
Authors: Bogdanov, Patricia; Duarri, Anna; Garcia-Arumi, Jose; Garcia-Arumi, Jose; Hernandez, Cristina; Hernandez, Cristina; Huerta, Jordi; Isla-Magrane, Helena; Ramos, Hugo; Sabater, David et al.
DOI: 10.2337/db23-0027
Efficacy and safety of temozolomide in the treatment of aggressive pituitary neuroendocrine tumours in Spain.
PMID: 37720528
Journal: Frontiers in Endocrinology
Year: 2023
Reference: Front Endocrinol (Lausanne). 2023 Aug 31;14:1204206. doi: 10.3389/fendo.2023.1204206. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Araujo-Castro, Marta; Biagetti, Betina; Biagetti, Betina; Camara, Rosa; Fajardo, Carmen; Garcia-Centeno, Rogelio; Guerrero-Perez, Fernando; Hanzu, Felicia; Iglesias, Pedro; Lamas, Cristina et al.
DOI: 10.3389/fendo.2023.1204206
Structural and metabolic retinal changes associated with mild cognitive impairment in type 2 diabetes.
PMID: 37725903
Journal: DIABETES
Year: 2023
Reference: Diabetes. 2023 Sep 19:db230025. doi: 10.2337/db23-0025.
Impact factor:
Publication type: Paper in international publication
Authors: Biessels, Geert Jan; Cheung, Carol Y; Exalto, Lieza; Grauslund, Jakob; Lois, Noemi; Pedersen, Frederik N; Peto, Tunde; Pouwer, Frans; Simo, Rafael; Stokholm, Lonny et al.
DOI: 10.2337/db23-0025
Prolactin and Growth Hormone Signaling and Interlink Focused on the Mammosomatotroph Paradigm: A Comprehensive Review of the Literature.
PMID: 37762304
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2023
Reference: Int J Mol Sci. 2023 Sep 12;24(18):14002. doi: 10.3390/ijms241814002.
Impact factor:
Publication type: Review in international publication
Authors: Araujo-Castro, Marta; Biagetti, Betina; Biagetti, Betina; Marazuela, Monica; Puig-Domingo, Manel et al.
DOI: 10.3390/ijms241814002
Effect of Resveratrol Content in Red Wine on Circulating Sex Hormone-Binding Globulin: Lessons from a Pilot Clinical Trial.
PMID: 35751841
Journal: MOLECULAR NUTRITION & FOOD RESEARCH
Year: 2022
Reference: Mol Nutr Food Res. 2022 Aug;66(16):e2200125. doi: 10.1002/mnfr.202200125. Epub 2022 Jul 1.
Impact factor:
Publication type: Paper in international publication
Authors: Brianso-Llort, Laura; Hernandez, Cristina; Ramos-Perez, Lorena; Selva, David M; Simo, Rafael; Simo-Servat, Olga; Torres-Torronteras, Javier et al.
DOI: 10.1002/mnfr.202200125
When Sugar Reaches the Liver: Phenotypes of Patients with Diabetes and NAFLD.
PMID: 35743358
Journal: Journal of Clinical Medicine
Year: 2022
Reference: J Clin Med. 2022 Jun 8;11(12). pii: jcm11123286. doi: 10.3390/jcm11123286.
Impact factor:
Publication type: Review in international publication
Authors: Banares, Juan; Ciudin, Andreea; Ferrer, Roser; Gabriel-Medina, Pablo; Manzano-Nunez, Ramiro; Martinez Selva, David; Pericas, Juan M; Rivera-Esteban, Jesus; Rojano-Toimil, Alba et al.
DOI: 10.3390/jcm11123286
Clinical efficacy of a virtual reality tool for the treatment of obesity: study protocol of a randomised controlled trial.
PMID: 35732390
Journal: BMJ Open
Year: 2022
Reference: BMJ Open. 2022 Jun 22;12(6):e060822. doi: 10.1136/bmjopen-2022-060822.
Impact factor:
Publication type: Paper in international publication
Authors: Anastasiadou, Dimitra; Cano Porras, Desiderio; Ciudin, Andreea; Comas, Marta; Lusilla-Palacios, Pilar; Puig, Gemma Parramon; Ramos-Quiroga, Jose Antonio; Slater, Mel; Spanlang, Bernhard; Vazquez-De Sebastian, Julia et al.
DOI: 10.1136/bmjopen-2022-060822
Review of SGLT2i for the Treatment of Renal Complications: Experience in Patients with and Without T2D.
PMID: 35704167
Journal: Diabetes Therapy
Year: 2022
Reference: Diabetes Ther. 2022 Jul;13(Suppl 1):35-49. doi: 10.1007/s13300-022-01276-2. Epub 2022 Jun 15.
Impact factor:
Publication type: Review in international publication
Authors: Aparicio-Sanchez, Jose Juan; Gonzalez-Albarran, Olga; Morales, Cristobal; Perez-Maraver, Manuel; Simo, Rafael et al.
DOI: 10.1007/s13300-022-01276-2
The Panoramic View of Revisional Bariatric Surgery.
PMID: 34492201
Journal: Journal of Laparoendoscopic & Advanced Surgical Techniques
Year: 2021
Reference: J Laparoendosc Adv Surg Tech A. 2021 Sep 6. doi: 10.1089/lap.2021.0506.
Impact factor:
Publication type: Paper in international publication
Authors: Armengol, Manel; Caubet, Enric; Cirera de Tudela, Arturo; Ciudin, Andrea; Fort, Jose Manuel; Garcia Ruiz de Gordejuela, Amador; Gonzalez, Oscar; Palermo, Mariano; Rodriguez Luna, Maria Rita; Vilallonga, Ramon et al.
DOI: 10.1089/lap.2021.0506
Relationship of Central Obesity with the Incidence of Cognitive Impairment and Dementia from cohort studies involving 5,060,687 participants.
PMID: 34464646
Journal: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
Year: 2021
Reference: Neurosci Biobehav Rev. 2021 Nov;130:301-313. doi: 10.1016/j.neubiorev.2021.08.028. Epub 2021 Aug 28.
Impact factor:
Publication type: Review in international publication
Authors: Cardoso, Marly Augusto; Lu, Ming; Simo, Rafael; Stehouwer, Coen D A; Sun, Ran; Tang, Xingyao; Tian, Wei; Xin, Zhong; Yang, Jinkui; Zhang, Ping et al.
DOI: 10.1016/j.neubiorev.2021.08.028
Neurovascular Unit: A New Target for Treating Early Stages of Diabetic Retinopathy.
PMID: 34452281
Journal: Pharmaceutics
Year: 2021
Reference: Pharmaceutics. 2021 Aug 23;13(8). pii: pharmaceutics13081320. doi: 10.3390/pharmaceutics13081320.
Impact factor:
Publication type: Review in international publication
Authors: Bogdanov, Patricia; Hernandez, Cristina; Simo, Rafael; Simo-Servat, Olga et al.
DOI: 10.3390/pharmaceutics13081320
The Gaze Fixation Assessed by Microperimetry: A Useful Tool for the Monitoring of the Cognitive Function in Patients with Type 2 Diabetes.
PMID: 34442342
Journal: Journal of Personalized Medicine
Year: 2021
Reference: J Pers Med. 2021 Jul 22;11(8). pii: jpm11080698. doi: 10.3390/jpm11080698.
Impact factor:
Publication type: Paper in international publication
Authors: Castellano-Tejedor, Carmina; Ciudin, Andreea; Hernandez, Cristina; Ortiz-Zuniga, Angel Michael; Rojano-Toimil, Alba; Simo, Rafael; Simo-Servat, Olga; Vazquez-de Sebastian, Julia et al.
DOI: 10.3390/jpm11080698
Effect of Subcutaneous Insulin on Spirometric Maneuvers in Patients with Type 1 Diabetes: A Case-Control Study.
PMID: 32344939
Journal: Journal of Clinical Medicine
Year: 2020
Reference: J Clin Med. 2020 Apr 25;9(5). pii: jcm9051249. doi: 10.3390/jcm9051249.
Impact factor:
Publication type: Paper in international publication
Authors: Barbe, Ferran; Carmona, Paola; Dalmases, Mireia; Gonzalez, Jessica; Gutierrez-Carrasquilla, Liliana; Hernandez, Cristina; Hernandez, Marta; Lecube, Albert; Lopez-Cano, Carolina; Marti, Raquel et al.
DOI: 10.3390/jcm9051249
Alteration of the Mitochondrial Effects of Ceria Nanoparticles by Gold: An Approach for the Mitochondrial Modulation of Cells Based on Nanomedicine.
PMID: 32295053
Journal: Nanomaterials
Year: 2020
Reference: Nanomaterials (Basel). 2020 Apr 13;10(4). pii: nano10040744. doi: 10.3390/nano10040744.
Impact factor:
Publication type: Paper in international publication
Authors: Abasolo, Ibane; Aparicio-Gomez, Carolina; Garcia, Hermenegildo; Gutierrez-Carcedo, Patricia; Herance, Jose Raul; Navalon, Sergio; Setoain, Xavier; Simo, Rafael; Victor, Victor Manuel et al.
DOI: 10.3390/nano10040744
Diagnosis, treatment and follow-up of patients with acromegaly in a clinical practice setting in Spain: the ACROPRAXIS program Delphi survey.
PMID: 31823249
Journal: Pituitary
Year: 2020
Reference: Pituitary. 2020 Apr;23(2):129-139. doi: 10.1007/s11102-019-01012-3.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez Escola, Cristina; Bernabeu, Ignacio; Biagetti, Betina; de Miguel, Paz; de Pablos-Velasco, Pedro; Diez, Juan Jose; Fajardo, Carmen; Gonzalez, Natividad; Paja, Miguel; Valdes, Nuria et al.
DOI: 10.1007/s11102-019-01012-3
New Metrics to Assess Type 2 Diabetes After Bariatric Surgery: The "Time-Within-Remission Range".
PMID: 32283783
Journal: Journal of Clinical Medicine
Year: 2020
Reference: J Clin Med. 2020 Apr 9;9(4). pii: jcm9041070. doi: 10.3390/jcm9041070.
Impact factor:
Publication type: Paper in international publication
Authors: Abuin, Jose; Arrizabalaga, Cristina; Arteaga, Magdalena; Ballesteros-Pomar, Maria D; Bandres, Orosia; Botana, Manuel Antonio; Breton, Irene; Bueno, Marta; Caixas, Assumpta; Calanas, Alfonso et al.
DOI: 10.3390/jcm9041070
Topical Treatment With Brimonidine and Somatostatin Causes Retinal Vascular Dilation in Patients With Early Diabetic Retinopathy From the EUROCONDOR.
PMID: 31112610
Journal: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Year: 2019
Reference: Invest Ophthalmol Vis Sci. 2019 May 1;60(6):2257-2262. doi: 10.1167/iovs.18-26487.
Impact factor:
Publication type: Paper in international publication
Authors: Cunha-Vaz, Jose; Fernandez-Carneado, Jimena; Frydkjaer-Olsen, Ulrik; Grauslund, Jakob; Hernandez, Cristina; Peto, Tunde; Ponsati, Berta; Simo, Rafael et al.
DOI: 10.1167/iovs.18-26487
The MOPEAD project: Advancing patient engagement for the detection of "hidden" undiagnosed cases of Alzheimer's disease in the community.
PMID: 31076376
Journal: Alzheimers & Dementia
Year: 2019
Reference: Alzheimers Dement. 2019 Jun;15(6):828-839. doi: 10.1016/j.jalz.2019.02.003. Epub 2019 May 7.
Impact factor:
Publication type: Review in international publication
Authors: Alegret, Montse; Belger, Mark; Bintener, Christophe; Boada, Merce; Bonn, Jaka; Campo, Laura; Ciudad, Antonio; Ciudin, Andreea; Dumas, Annette; Ferreira, Daniel et al.
DOI: 10.1016/j.jalz.2019.02.003
Glucose Restriction Promotes Osteocyte Specification by Activating a PGC-1alpha-Dependent Transcriptional Program.
PMID: 31039455
Journal: iScience
Year: 2019
Reference: iScience. 2019 May 31;15:79-94. doi: 10.1016/j.isci.2019.04.015. Epub 2019 Apr 12.
Impact factor:
Publication type: Paper in international publication
Authors: Artigas, Natalia; Gama-Perez, Pau; Garcia-Roves, Pablo M; Pimenta-Lopes, Carolina; Rosa, Jose Luis; Sanchez-de-Diego, Cristina; Torrejon, Benjamin; Valer, Jose Antonio; Ventura, Francesc; Villena, Josep A et al.
DOI: 10.1016/j.isci.2019.04.015
DNA methylation in thyroid cancer.
PMID: 31035251
Journal: ENDOCRINE-RELATED CANCER
Year: 2019
Reference: Endocr Relat Cancer. 2019 Jul;26(7):R415-R439. doi: 10.1530/ERC-19-0093.
Impact factor:
Publication type: Review in international publication
Authors: Gil, Joan; Jorda, Mireia; Perez-Gonzalez, Beatriz; Zafon Llopis, Carles et al.
DOI: 10.1530/ERC-19-0093
Detection of serrated lesions in proximal colon by simulated sigmoidoscopy vs faecal immunochemical testing in a multicentre, pragmatic, randomised controlled trial.
PMID: 30574323
Journal: United European Gastroenterology Journal
Year: 2018
Reference: United European Gastroenterol J. 2018 Dec;6(10):1527-1537. doi: 10.1177/2050640618804722. Epub 2018 Sep 26.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Urturi, Cristina; Andreu, Montserrat; Balaguer, Francesc; Bessa, Xavier; Bujanda, Luis; Carballo, Fernando; Carot, Laura; Castells, Antoni; Cubiella, Joaquin; Hernandez, Cristina et al.
DOI: 10.1177/2050640618804722
Topical Administration of Bosentan Prevents Retinal Neurodegeneration in Experimental Diabetes.
PMID: 30428543
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2018
Reference: Int J Mol Sci. 2018 Nov 13;19(11). pii: ijms19113578. doi: 10.3390/ijms19113578.
Impact factor: 3.687
Publication type: Paper in international publication
Authors: Ramos, Hugo, Guerrero, Marta, Sune-Negre, Josep Maria, Tico, Josep Ramon, Montoro, Bruno, Duran, Vicente, Arias, Luis, Hernandez, Cristina, Simo, Rafael, Garcia-Ramirez, Marta et al.
DOI: 10.3390/ijms19113578
Effects of Liposomal Formulation of Citicoline in Experimental Diabetes-Induced Retinal Neurodegeneration.
PMID: 30127248
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2018
Reference: Int J Mol Sci. 2018 Aug 20;19(8). pii: ijms19082458. doi: 10.3390/ijms19082458.
Impact factor: 3.687
Publication type: Paper in international publication
Authors: Sampedro, Joel, Sola-Adell, Cristina, Simo-Servat, Olga, Russo, Carla, Varela-Sende, Luisa, Simo, Rafael, Hernandez, Cristina, Bogdanov, Patricia et al.
DOI: 10.3390/ijms19082458
Assessment of advanced glycation end-products as a biomarker of diabetic outcomes.
PMID: 30077632
Journal: Endocrinologia, diabetes y nutricion
Year: 2018
Reference: Endocrinol Diabetes Nutr. 2018 Nov;65(9):540-545. doi: 10.1016/j.endinu.2018.06.003. Epub 2018 Aug 2.
Impact factor: 0
Publication type: Paper in national publication
Authors: Simo-Servat, Olga, Planas, Alejandra, Ciudin, Andreea, Simo, Rafael, Hernandez, Cristina et al.
DOI: 10.1016/j.endinu.2018.06.003
Topical administration of DPP-IV inhibitors prevents retinal neurodegeneration in experimental diabetes.
PMID: 28779212
Journal: DIABETOLOGIA
Year: 2017
Reference: Diabetologia. 2017 Nov;60(11):2285-2298. doi: 10.1007/s00125-017-4388-y. Epub 2017 Aug 4.
Impact factor:
Publication type: Paper in international publication
Authors: Bogdanov, Patricia; Garcia-Ramirez, Marta; Genis, Xavier; Hernandez, Cristina; Sampedro, Joel; Simo, Rafael; Simo-Servat, Olga; Sola-Adell, Cristina; Valeri, Marta et al.
DOI: 10.1007/s00125-017-4388-y
Axitinib treatment in advanced RAI-resistant differentiated thyroid cancer (DTC) and refractory medullary thyroid cancer (MTC).
PMID: 28687563
Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY
Year: 2017
Reference: Eur J Endocrinol. 2017 Oct;177(4):309-317. doi: 10.1530/EJE-17-0243. Epub 2017 Jul 7.
Impact factor:
Publication type: Paper in international publication
Authors: Aller, Javier; Bohn, Uriel; Capdevila, Jaume; Cillan, Elena; Duran, Manuel; Garcia-Adrian, Silvia; Gonzalez-Astorga, Beatriz; Grande, Enrique; Grau, Juan Jose; Lopez-Alfonso, Ana et al.
DOI: 10.1530/EJE-17-0243
Update on Diagnosis and Treatment of Diabetic Retinopathy: A Consensus Guideline of the Working Group of Ocular Health (Spanish Society of Diabetes and Spanish Vitreous and Retina Society).
PMID: 28695003
Journal: Journal of Ophthalmology
Year: 2017
Reference: J Ophthalmol. 2017;2017:8234186. doi: 10.1155/2017/8234186. Epub 2017 Jun 14.
Impact factor:
Publication type: Review in international publication
Authors: Corcostegui, Borja; Duran, Santiago; Gonzalez-Albarran, Maria Olga; Hernandez, Cristina; Ruiz-Moreno, Jose Maria; Salvador, Javier; Simo, Rafael; Udaondo, Patricia et al.
DOI: 10.1155/2017/8234186
Functional and Structural Findings of Neurodegeneration in Early Stages of Diabetic Retinopathy. Cross-sectional Analyses of Baseline Data of the EUROCONDOR project.
PMID: 28663190
Journal: DIABETES
Year: 2017
Reference: Diabetes. 2017 Sep;66(9):2503-2510. doi: 10.2337/db16-1453. Epub 2017 Jun 29.
Impact factor:
Publication type: Paper in international publication
Authors: Aldington Hnd, Stephen J; Bandello, Francesco; Costa, Miguel Angelo; Cunha-Vaz, Jose; Egan, Catherine; Frydkjaer-Olsen, Ulrik; Garcia-Arumi, Jose; Gibson, Jonathan; Grauslund DMSci, Jakob; Harding, Simon P et al.
DOI: 10.2337/db16-1453
Concordance study between one-step nucleic acid amplification and morphologic techniques to detect lymph node metastasis in papillary carcinoma of the thyroid.
PMID: 26614398
Journal: HUMAN PATHOLOGY
Year: 2016
Reference: Hum Pathol. 2016 Feb;48:132-41. doi: 10.1016/j.humpath.2015.09.020. Epub 2015 Oct 3.
Impact factor:
Publication type: Paper in international publication
Authors: Baena, Jose Antonio; Cuevas, Dolors; de Alava, Enrique; Del Carmen, Sofia; Franch-Arcas, Guzman; Gatius, Sonia; Gonzalez, Oscar; Iglesias, Carmela; Macias, Carmen Garcia; Martinez, Mercedes et al.
DOI: 10.1016/j.humpath.2015.09.020
Diabetic and dyslipidaemic morbidly obese exhibit more liver alterations compared with healthy morbidly obese.
PMID: 27051590
Journal: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
Year: 2016
Reference: BBA Clin. 2016 Jan 8;5:54-65. doi: 10.1016/j.bbacli.2015.12.002. eCollection 2016 Jun.
Impact factor:
Publication type: Paper in international publication
Authors: Baena-Fustegueras, Juan Antonio; Balibrea, Jose Maria; Caubet, Enric; Ferrer, Roser; Fort, Jose Manuel; Gonzalez, Oscar; Lecube, Albert; Pardina, Eva; Peinado-Onsurbe, Julia; Rossell, Joana et al.
DOI: 10.1016/j.bbacli.2015.12.002
Obesity Determines the Immunophenotypic Profile and Functional Characteristics of Human Mesenchymal Stem Cells From Adipose Tissue.
PMID: 26956208
Journal: Stem Cells Translational Medicine
Year: 2016
Reference: Stem Cells Transl Med. 2016 Apr;5(4):464-75. doi: 10.5966/sctm.2015-0161. Epub 2016 Mar 8.
Impact factor:
Publication type: Paper in international publication
Authors: Duran, Xevi; Ejarque, Miriam; Fernandez-Veledo, Sonia; Oliva-Olivera, W; Pachon-Pena, Gisela; Petriz, Jordi; Serena, Carolina; Simo, Rafael; Tinahones, Francisco J; Vendrell, Joan et al.
DOI: 10.5966/sctm.2015-0161
The progress in understanding and treatment of diabetic retinopathy.
PMID: 26297071
Journal: PROGRESS IN RETINAL AND EYE RESEARCH
Year: 2016
Reference: Prog Retin Eye Res. 2016 Mar;51:156-86. doi: 10.1016/j.preteyeres.2015.08.001. Epub 2015 Aug 18.
Impact factor:
Publication type: Review in international publication
Authors: Chen, Mei; Curtis, Tim M; Gardiner, Thomas A; Hammes, Hans-Peter; Jenkins, Alicia; Lois, Noemi; Lyons, Timothy J; McKay, Gareth J; Medina, Reinhold J; Simo, Rafael et al.
DOI: 10.1016/j.preteyeres.2015.08.001
Characterization of sleep breathing pattern in patients with type 2 diabetes: sweet sleep study.
PMID: 25760760
Journal: PLOS ONE
Year: 2015
Reference: PLoS One. 2015 Mar 11;10(3):e0119073. doi: 10.1371/journal.pone.0119073. eCollection 2015.
Impact factor:
Publication type: Paper in international publication
Authors: Ciudin, Andreea; Hernandez, Cristina; Lecube, Albert; Romero, Odile; Sampol, Gabriel; Simo, Rafael et al.
DOI: 10.1371/journal.pone.0119073
New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond.
PMID: 25495651
Journal: FEBS J
Year: 2015
Reference: FEBS J. 2015 Feb;282(4):647-72. doi: 10.1111/febs.13175. Epub 2015 Jan 12.
Impact factor:
Publication type: Paper in international publication
Authors: Villena, Josep A et al.
DOI: 10.1111/febs.13175
RET Cys634Arg mutation confers a more aggressive multiple endocrine neoplasia type 2A phenotype than Cys634Tyr mutation.
PMID: 25515555
Journal: EUR J ENDOCRINOL
Year: 2015
Reference: Eur J Endocrinol. 2015 Mar;172(3):301-7. doi: 10.1530/EJE-14-0818. Epub 2014 Dec 16.
Impact factor:
Publication type: Paper in international publication
Authors: Alcazar, Victoria; CastaNo, Luis; Casteras, Anna; Forga Llenas, Lluis; Gaztambide, Sonia; Lamas, Cristina; Mesa, Jordi; Navarro, Elena; Tebar, Javier; Valdes, Nuria et al.
DOI: 10.1530/EJE-14-0818
Iodine Deficiency Is Higher in Morbid Obesity in Comparison with Late After Bariatric Surgery and Non-obese Women.
PMID: 24908244
Journal: OBES SURG
Year: 2015
Reference: Obes Surg. 2015 Jan;25(1):85-9. doi: 10.1007/s11695-014-1313-z.
Impact factor:
Publication type: Paper in international publication
Authors: Baena, Juan Antonio; Caubet, Enric; Fort, Jose Manuel; Gromaz, Adoracion; Lecube, Albert; Tortosa, Frederic; Zafon, Carles et al.
DOI: 10.1007/s11695-014-1313-z
Adiponectin Upregulates SHBG Production: Molecular Mechanisms and Potential Implications.
PMID: 24828613
Journal: ENDOCRINOLOGY
Year: 2014
Reference: Endocrinology. 2014 Aug;155(8):2820-30. doi: 10.1210/en.2014-1072. Epub 2014 May 14.
Impact factor: 4.644
Publication type: Paper in international publication
Authors: Simo, Rafael, Saez-Lopez, Cristina, Lecube, Albert, Hernandez, Cristina, Fort, Jose Manuel, Selva, David M et al.
DOI: 10.1210/en.2014-1072
Clinical challenges in the management of isolated GH deficiency type IA in adulthood.
PMID: 24683479
Journal: Endocrinology, diabetes & metabolism case reports
Year: 2014
Reference: Endocrinol Diabetes Metab Case Rep. 2014;2014:130057. doi: 10.1530/EDM-13-0057. Epub 2014 Feb 1.
Impact factor:
Publication type: Letter or abstract
Authors: Casteras, Anna, Kratzsch, Jurgen, Ferrandez, Angel, Zafon, Carles, Carrascosa, Antonio, Mesa, Jordi et al.
DOI: 10.1530/EDM-13-0057
Bariatric surgery in morbidly obese patients improves the atherogenic qualitative properties of the plasma lipoproteins.
PMID: 24674904
Journal: ATHEROSCLEROSIS
Year: 2014
Reference: Atherosclerosis. 2014 May;234(1):200-5. doi: 10.1016/j.atherosclerosis.2014.02.034. Epub 2014 Mar 14.
Impact factor: 3.971
Publication type: Paper in international publication
Authors: Julve, Josep, Pardina, Eva, Perez-Cuellar, Montserrat, Ferrer, Roser, Rossell, Joana, Baena-Fustegueras, Juan Antonio, Fort, Jose Manuel, Lecube, Albert, Blanco-Vaca, Francisco, Sanchez-Quesada, Jose Luis et al.
DOI: 10.1016/j.atherosclerosis.2014.02.034
Glycogen storage in the human retinal pigment epithelium: a comparative study of diabetic and non-diabetic donors.
PMID: 24458975
Journal: ACTA DIABETOL
Year: 2014
Reference: Acta Diabetol. 2014 Aug;51(4):543-52. doi: 10.1007/s00592-013-0549-8. Epub 2014 Jan 24.
Impact factor: 3.679
Publication type: Paper in international publication
Authors: Garcia-Ramirez, Marta, Garcia-Rocha, Mar, Saez-Lopez, Cristina, Valverde, Angela M, Guinovart, Joan J, Simo, Rafael, Hernandez, Cristina et al.
DOI: 10.1007/s00592-013-0549-8
Molecular Implications of the PPARs in the Diabetic Eye.
PMID: 23431285
Journal: PPAR Research
Year: 2013
Reference: PPAR Res. 2013;2013:686525. doi: 10.1155/2013/686525. Epub 2013 Feb 4.
Impact factor:
Publication type: Paper in international publication
Authors: Ciudin, Andreea; Hernandez, Cristina; Simo, Rafael et al.
DOI: 10.1155/2013/686525
Non-islet cell induced hypoglycemia by "big-IGF-2" in a patient with retroperitoneal solitary fibrous tumor and a papillary thyroid carcinoma: An unusual association.
PMID: 23333637
Journal: Endocrinologia y nutricion
Year: 2013
Reference: Endocrinol Nutr. 2013 Oct;60(8):483-4. doi: 10.1016/j.endonu.2012.10.004. Epub 2013 Jan 18.
Impact factor:
Publication type: Letter or abstract
Authors: Ciudin, Andreea; Hernandez, Cristina; Lecube, Albert; Mesa, Jordi; Simo, Rafael et al.
DOI: 10.1016/j.endonu.2012.10.004
Proapoptotic and survival signaling in the neuroretina at early stages of diabetic retinopathy.
PMID: 23335850
Journal: MOLECULAR VISION
Year: 2013
Reference: Mol Vis. 2013;19:47-53. Epub 2013 Jan 7.
Impact factor:
Publication type: Paper in international publication
Authors: Garcia-Ramirez, Marta; Gonzalez-Rodriguez, Agueda; Hernandez, Cristina; Miranda, Soledad; Simo, Rafael; Valverde, Angela M et al.
DOI:
[Abnormalities of carbohydrate metabolism in acromegaly].
PMID: 24012444
Journal: MEDICINA CLINICA
Year: 2013
Reference: Med Clin (Barc). 2013 Nov 16;141(10):442-6. doi: 10.1016/j.medcli.2013.05.035. Epub 2013 Sep 6.
Impact factor: 1.399
Publication type: Paper in national publication
Authors: Biagetti, Betina, Obiols, Gabriel, Valladares, Silvia, Arnez, Lorena, Dalama, Belen, Mesa, Jordi et al.
DOI: 10.1016/j.medcli.2013.05.035
Potential Role of Tumor Necrosis Factor-alpha in Downregulating Sex Hormone-Binding Globulin.
PMID: 22210320
Journal: DIABETES
Year: 2012
Reference: Diabetes. 2012 Feb;61(2):372-82. Epub 2011 Dec 30.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; et al.
DOI: 10.2337/db11-0727
Molecular Mechanism of TNFalpha-Induced Down-Regulation of SHBG Expression.
PMID: 22301786
Journal: MOLECULAR ENDOCRINOLOGY
Year: 2012
Reference: Mol Endocrinol. 2012 Mar;26(3):438-46. doi: 10.1210/me.2011-1321. Epub 2012 Feb 2.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; et al.
DOI: 10.1210/me.2011-1321
Proteomic analysis of cerebrospinal fluid from obese women with idiopathic intracranial hypertension: a new approach for identifying new candidates in the pathogenesis of obesity.
PMID: 22296024
Journal: JOURNAL OF NEUROENDOCRINOLOGY
Year: 2012
Reference: J Neuroendocrinol. 2012 Jun;24(6):944-52. doi: 10.1111/j.1365-2826.2012.02288.x.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; et al.
DOI: 10.1111/j.1365-2826.2012.02288.x
Diabetes is the main factor accounting for hypomagnesemia in obese subjects.
PMID: 22291997
Journal: PLoS One
Year: 2012
Reference: PLoS One. 2012;7(1):e30599. Epub 2012 Jan 24.
Impact factor:
Publication type: Paper in international publication
Authors: Baena-Fustegueras, Juan Antonio; Fort, Jose Manuel; Hernandez, Cristina; Lecube, Albert; Pelegri, Dolors; Simo, Rafael et al.
DOI: 10.1371/journal.pone.0030599
Erythropoietin protects retinal pigment epithelial cells against the increase of permeability induced by diabetic conditions: Essential role of JAK2/ PI3K signaling.
PMID: 21620963
Journal: CELLULAR SIGNALLING
Year: 2011
Reference: Cell Signal. 2011 Oct;23(10):1596-602. Epub 2011 May 19.
Impact factor: 4.243
Publication type: Paper in international publication
Authors: , , , , , , et al.
DOI: 10.1016/j.cellsig.2011.05.011
Successful treatment of the Dunningan-type familial partial lipodystrophy with Roux-en-Y Gastric Bypass.
PMID: 21521325
Journal: CLINICAL ENDOCRINOLOGY
Year: 2011
Reference: Clin Endocrinol (Oxf). 2011 Sep;75(3):403-4. doi: 10.1111/j.1365-2265.2011.04057.x.
Impact factor: 3.323
Publication type: Letter or abstract
Authors: , , , , , et al.
DOI: 10.1111/j.1365-2265.2011.04057.x
Isolated langerhans cell histiocytosis of the thyroid in an adult female: one-year followup.
PMID: 21461403
Journal: International Journal of Endocrinology
Year: 2011
Reference: Int J Endocrinol. 2011;2011:898302. Epub 2011 Mar 6.
Impact factor: 0.727
Publication type: Paper in international publication
Authors: Ruiz Marcellan, Mari Carmen, Vilallonga, Ramon, Ciudin, Andrea, Fort, Jose Manuel, Baena, Juan Antonio, Gonzalez, Oscar, Armengol, Manuel, Mesa, Jordi et al.
DOI: 10.1155/2011/898302
[Long term treatment with growth hormone deficiency in adults.]
PMID: 21411111
Journal: MEDICINA CLINICA
Year: 2011
Reference: Med Clin (Barc). 2011 May 28;136(15):659-64. Epub 2011 Mar 15.
Impact factor: 1.413
Publication type: Paper in national publication
Authors: , , , et al.
DOI: 10.1016/j.medcli.2010.07.030
Iron in obesity. An ancient micronutrient for a modern disease.
PMID: 19619262
Journal: Obesity Reviews
Year: 2010
Reference: Obes Rev. 2010 Apr;11(4):322-8. Epub 2009 Jul 10.
Impact factor: 5.086
Publication type: Review in international publication
Authors: Zafon, C, Lecube, A, Simo, R et al.
DOI: 10.1111/j.1467-789X.2009.00638.x
Endoscopic Management of Drain Inclusion in the Gastric Pouch after Gastrojejunal Leakage after Laparoscopic Roux-en-Y Gastric Bypass for the Treatment of Morbid Obesity (LRYGBP).
PMID: 20634928
Journal: Diagnostic and therapeutic endoscopy
Year: 2010
Reference: Diagn Ther Endosc. 2010;2010:891345. Epub 2010 Jun 20.
Impact factor:
Publication type: Letter or abstract
Authors: Fort, Jose Manuel, Gonzalez, Oscar, Baena, Juan Antonio, Lecube, Albert, Salord, Jose, Armengol Carrasco, Manel, Armengol-Miro, Josep Ramon, Vilallonga, Ramon et al.
DOI: 10.1155/2010/891345
New pathogenic candidates for diabetic macular edema detected by proteomic analysis.
PMID: 20587712
Journal: DIABETES CARE
Year: 2010
Reference: Diabetes Care. 2010 Jul;33(7):e92.
Impact factor: 6.718
Publication type: Letter or abstract
Authors: Hernandez, Cristina, Garcia-Ramirez, Marta, Colome, Nuria, Villarroel, Marta, Corraliza, Lidia, Garcia-Pacual, Luis, Casado, Joan, Canals, Francesc, Simo, Rafael et al.
DOI: 10.2337/dc10-0232
Insulin resistance is related to impaired lung function in morbidly obese women: a case-control study.
PMID: 20882512
Journal: DIABETES-METABOLISM RESEARCH AND REVIEWS
Year: 2010
Reference: Diabetes Metab Res Rev. 2010 Nov;26(8):639-45. doi: 10.1002/dmrr.1131. Epub 2010 Sep 29.
Impact factor: 2.762
Publication type: Paper in international publication
Authors: , , , , , et al.
DOI: 10.1002/dmrr.1131
Lower zinc-alpha2-glycoprotein production by adipose tissue and liver in obese patients unrelated to insulin resistance.
PMID: 19622624
Journal: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Year: 2009
Reference: J Clin Endocrinol Metab. 2009 Nov;94(11):4499-507.
Impact factor: 6.325
Publication type: Paper in international publication
Authors: Selva, David M, Lecube, Albert, Hernandez, Cristina, Baena, Juan A, Fort, Jose M, Simo, Rafael et al.
DOI: 10.1210/jc.2009-0758
Gene expression of paired abdominal adipose AQP7 and liver AQP9 in patients with morbid obesity: relationship with glucose abnormalities.
PMID: 19615702
Journal: METABOLISM-CLINICAL AND EXPERIMENTAL
Year: 2009
Reference: Metabolism. 2009 Dec;58(12):1762-8.
Impact factor: 2.92
Publication type: Paper in international publication
Authors: Miranda, Merce, Ceperuelo-Mallafre, Victoria, Lecube, Albert, Hernandez, Cristina, Chacon, Matilde R, Gallart, Lluis, Baena-Fustegueras, Juan A, Simo, Rafael, Vendrell, Joan, Fort, Jose M et al.
DOI: 10.1016/j.metabol.2009.06.004
Normoalbuminuric type 1 diabetic patients with retinopathy have an impaired tubular response to desmopressin: its relationship with plasma endothelin-1.
PMID: 19293263
Journal: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Year: 2009
Reference: J Clin Endocrinol Metab. 2009 Jun;94(6):2060-5.
Impact factor: 6.325
Publication type: Paper in international publication
Authors: Corraliza, Lidia, Hernandez, Cristina, Rodriguez, Beatriz, Losada, Eladio, Simo, Rafael, Garcia-Ramirez, Marta et al.
DOI: 10.1210/jc.2008-2784
Diabetes is an independent risk factor for severe nocturnal hypoxemia in obese patients. A case-control study.
PMID: 19262746
Journal: PLoS One
Year: 2009
Reference: PLoS One. 2009;4(3):e4692.
Impact factor:
Publication type: Letter or abstract
Authors: Simo, Rafael, Lecube, Albert, Sampol, Gabriel, Lloberes, Patricia, Romero, Odile, Mesa, Jordi, Hernandez, Cristina et al.
DOI: 10.1371/journal.pone.0004692
News
The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.
This investment from EIT Health in the project will enable D-Sight to progress in the clinical development of its groundbreaking treatment for the early stages of diabetic retinopathy.
This initiative of the ”la Caixa” Foundation offers the selected entrepreneurial scientists financial support and support through individual mentoring and training.